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The map label for this gene is aceE [H]

Identifier: 73540997

GI number: 73540997

Start: 1395097

End: 1397784

Strand: Direct

Name: aceE [H]

Synonym: Reut_A1303

Alternate gene names: 73540997

Gene position: 1395097-1397784 (Clockwise)

Preceding gene: 73540994

Following gene: 73540998

Centisome position: 36.65

GC content: 64.1

Gene sequence:

>2688_bases
ATGTCCGCCGTACCCGAGCAGATTCTCGGCGCATCCAGCGCCAACGACGCCGATCCCCAGGAAACCCACGAATGGCTTGA
TGCTCTGCAAGGCGTCATCGCCGCAGAGGGCTCAGAACGCGCGGCCTTCCTGATCGACAAGCAAATCGAGTACGCACGCG
TGAATGGCGTTACGCAGCCGTTCCACGCCGAAACGCAGTACATCAACACGATCCCCGTCGAGCAGCAGGCACGTATTCCC
GGCGACCAGGATATCGAGCACCGCATCCGCTCGTACACGCGCTGGAACGCGATGGCGATGGTGCTGCGCGCCAACAAGCA
CACCAACGTCGGCGGCCACATCTCCTCGTTTGCCTCGGCGGCCACGCTGTATGACGTCGGCTACAACCACTTCTGGCGTG
CTCCGTCGGAACAGAGTGGTGGCGACCTGGTATTCGTGCAGGGCCACTCGGCGCCGGGCGTGTACTCGCGCGCATTCCTG
CTGGGCCGCCTGACCCCGGACCAGCTCGACAGCTTCCGCCAGGAAGTGGACGGCAAGGGCATTTCGTCGTACCCGCACCC
GTGGCTGATGCCGGACTTCTGGCAGTTCCCGACCGTGTCGATGGGCCTGGGCCCGATCATGGCCATCTACCAGGCCCGCT
TCATGAAGTACCTGGACAGCCGCGGCCTGGCCAAGGCCGGCGACCGCAAGGTCTGGGCCTTCCTCGGCGACGGCGAAACC
GACGAGCCGGAATCGCTGGGCGCGATCGGCATGGCCGGCCGCGAGAAGCTGGACAACCTGGTCTTCGTCATCAACTGCAA
CCTGCAGCGCCTGGACGGTCCGGTGCGCGGCAACGGCAAGATCATCCAGGAACTGGAGTCCGAATTCCGCGGTGCCGGCT
GGAACGTGATCAAGGTGGTGTGGGGCAGCAAGTGGGATTCCCTGCTGGCGCGCGACACCAAGGGCCTGCTGATGAAGCGC
ATGATGGATTGCGTGGACGGCGAGTACCAGACCATGAAGGCCAAGGACGGCGCTTACGTCCGCGAGCACTTCTTCAACTC
GCCTGAACTGAAGGCGATGGTTGCCGACTGGTCCGACGACGACATCTGGCGCCTGAACCGTGGCGGCCACGACCCGCACA
AGATCTACGCGGCCTACAAGGCTGCCAGCGAGCACAAGGGCCAGCCGACGCTGATCCTGGCCAAGACCATCAAGGGCTAT
GGCATGGGCGATGCCGGTCAGGCCATGAACGTGGCCCACCAGCAGAAGAAGATGCCGGTGGACGCGATCCGCAAGTTCCG
CGACCAGTTCAACCTTCCGGTGCCCGACGACAAGCTCGACGAAGTGCCGTACATCACCTTCCCCGAAGGCTCGAAGGAAC
TGGAATACATGCGCCAGGCGCGCATGAACCTGGGCGGCTACCTGCCGGCGCGCCGCCAAAAGGCCGAAGCGCTGCAGATC
CCGCAGCTGTCCGCGTTCGACGCGCTGCTGAAGGCCACCGGCGAAGGCCGCGAAGTGTCCACCACCATGGCCTTCGTGCG
TATCCTCAACACGCTGCTGAAAGACAAGCAGATCGGCAAGCACGTGGTGCCCATCGTGCCGGACGAGTCGCGTACCTTCG
GCATGGAAGGCCTGTTCCGTCAGGTCGGGATCTGGAACCAGGAAGGCCAGAAGTACGTCCCGGAAGACCATGACCAGCTC
ATGTTCTACAAGGAATCGCAGACTGGCCAGGTGCTGCAGGAAGGCATCAACGAAGCCGGCGCCATGTGCGACTGGATCGC
CGCCGCTACGTCGTACTCGACGCACGGCGTGCAGATGATCCCGTTCTACATCTACTACTCGATGTTCGGCATCCAGCGTA
TCGGCGACCTGTGCTGGGCGGCGGCCGACATGCGTTCGCGCGGCTTCCTGCTGGGCGGCACCGCCGGCCGGACCACGCTG
AACGGCGAAGGCCTGCAGCACGAAGACGGCCACTCGCACGTGTTCCACTCGGTGATCCCGAACTGCATCTCGTATGACCC
GACCTTCCAGTACGAACTGGCGGTGATCATGCAGGACGGCCTGCGCCGCATGTACGCCGAGCAGGAAGACGTCTACTACT
ACCTGACGGTGATGAACGAGAACTACGAGCATCCGGAAATGCCGGCTGGCGTAGAGCAGGACATTGTCAAGGGCATGTAC
CAGTTCCGCAAGGGCGTCGAGAACAGCAACGCGCCGCGCGTGCAGTTGCTGGGCTCGGGCACGATCTTCCGCGAGGTGAT
CGCCGCCGCCGAACTGCTCAAGAAGGACTGGGGCGTGGAATCGGACCTGTGGGGCTGCCCGAGCTTCACCGAGCTGGCCC
GCGAAGGCCAGGCCGCCGAGCGCTTCAACCTGCTGCACCCGGCCGAGCCCCAGCGCGAGTCGTTCGTCGCGCAGAAGCTC
AAGTCGGCGCGCGGTCCGGTCATTGCCTCGACCGACTATGTGCGTGCGTTTGCCGAACAGATCCGTCCGTTCGTGCCGCG
CCGCTATGTCGTGCTGGGCACCGACGGCTTCGGCCGCTCGGACACCCGCGAAAAGCTGCGTCACTTCTTCGAGGTGGATC
GCCACTGGGTCACGCTGGCCGCGCTGAAGGCGCTGGCCGACGAAGGCGCCATCAGCCGCGACAAGGTGGCTGAAGCGATC
AAGAAGTACAACCTCGATCCCAACAAGCCGAATCCGATGTCGGTCTGA

Upstream 100 bases:

>100_bases
AGGCGCTGCGGCGACGCATCCGCAAGTCATACCCCGTCACCCCAGGGGCCCGAATGCCAAAAGCCAGGGTCCCGGAGCAG
GAATTCACCAGGAGACAGTC

Downstream 100 bases:

>100_bases
CCGGCTTCCTGCACCAACCCCCGCAGTACGGCGACGCCGTGCCGCGGGCGCCCCGGAAATCCGGTGGCGCCTTGCGGCAC
AGCGGCGTGACAGAAGCGGG

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 895; Mature: 894

Protein sequence:

>895_residues
MSAVPEQILGASSANDADPQETHEWLDALQGVIAAEGSERAAFLIDKQIEYARVNGVTQPFHAETQYINTIPVEQQARIP
GDQDIEHRIRSYTRWNAMAMVLRANKHTNVGGHISSFASAATLYDVGYNHFWRAPSEQSGGDLVFVQGHSAPGVYSRAFL
LGRLTPDQLDSFRQEVDGKGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLDSRGLAKAGDRKVWAFLGDGET
DEPESLGAIGMAGREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWGSKWDSLLARDTKGLLMKR
MMDCVDGEYQTMKAKDGAYVREHFFNSPELKAMVADWSDDDIWRLNRGGHDPHKIYAAYKAASEHKGQPTLILAKTIKGY
GMGDAGQAMNVAHQQKKMPVDAIRKFRDQFNLPVPDDKLDEVPYITFPEGSKELEYMRQARMNLGGYLPARRQKAEALQI
PQLSAFDALLKATGEGREVSTTMAFVRILNTLLKDKQIGKHVVPIVPDESRTFGMEGLFRQVGIWNQEGQKYVPEDHDQL
MFYKESQTGQVLQEGINEAGAMCDWIAAATSYSTHGVQMIPFYIYYSMFGIQRIGDLCWAAADMRSRGFLLGGTAGRTTL
NGEGLQHEDGHSHVFHSVIPNCISYDPTFQYELAVIMQDGLRRMYAEQEDVYYYLTVMNENYEHPEMPAGVEQDIVKGMY
QFRKGVENSNAPRVQLLGSGTIFREVIAAAELLKKDWGVESDLWGCPSFTELAREGQAAERFNLLHPAEPQRESFVAQKL
KSARGPVIASTDYVRAFAEQIRPFVPRRYVVLGTDGFGRSDTREKLRHFFEVDRHWVTLAALKALADEGAISRDKVAEAI
KKYNLDPNKPNPMSV

Sequences:

>Translated_895_residues
MSAVPEQILGASSANDADPQETHEWLDALQGVIAAEGSERAAFLIDKQIEYARVNGVTQPFHAETQYINTIPVEQQARIP
GDQDIEHRIRSYTRWNAMAMVLRANKHTNVGGHISSFASAATLYDVGYNHFWRAPSEQSGGDLVFVQGHSAPGVYSRAFL
LGRLTPDQLDSFRQEVDGKGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLDSRGLAKAGDRKVWAFLGDGET
DEPESLGAIGMAGREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWGSKWDSLLARDTKGLLMKR
MMDCVDGEYQTMKAKDGAYVREHFFNSPELKAMVADWSDDDIWRLNRGGHDPHKIYAAYKAASEHKGQPTLILAKTIKGY
GMGDAGQAMNVAHQQKKMPVDAIRKFRDQFNLPVPDDKLDEVPYITFPEGSKELEYMRQARMNLGGYLPARRQKAEALQI
PQLSAFDALLKATGEGREVSTTMAFVRILNTLLKDKQIGKHVVPIVPDESRTFGMEGLFRQVGIWNQEGQKYVPEDHDQL
MFYKESQTGQVLQEGINEAGAMCDWIAAATSYSTHGVQMIPFYIYYSMFGIQRIGDLCWAAADMRSRGFLLGGTAGRTTL
NGEGLQHEDGHSHVFHSVIPNCISYDPTFQYELAVIMQDGLRRMYAEQEDVYYYLTVMNENYEHPEMPAGVEQDIVKGMY
QFRKGVENSNAPRVQLLGSGTIFREVIAAAELLKKDWGVESDLWGCPSFTELAREGQAAERFNLLHPAEPQRESFVAQKL
KSARGPVIASTDYVRAFAEQIRPFVPRRYVVLGTDGFGRSDTREKLRHFFEVDRHWVTLAALKALADEGAISRDKVAEAI
KKYNLDPNKPNPMSV
>Mature_894_residues
SAVPEQILGASSANDADPQETHEWLDALQGVIAAEGSERAAFLIDKQIEYARVNGVTQPFHAETQYINTIPVEQQARIPG
DQDIEHRIRSYTRWNAMAMVLRANKHTNVGGHISSFASAATLYDVGYNHFWRAPSEQSGGDLVFVQGHSAPGVYSRAFLL
GRLTPDQLDSFRQEVDGKGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLDSRGLAKAGDRKVWAFLGDGETD
EPESLGAIGMAGREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWGSKWDSLLARDTKGLLMKRM
MDCVDGEYQTMKAKDGAYVREHFFNSPELKAMVADWSDDDIWRLNRGGHDPHKIYAAYKAASEHKGQPTLILAKTIKGYG
MGDAGQAMNVAHQQKKMPVDAIRKFRDQFNLPVPDDKLDEVPYITFPEGSKELEYMRQARMNLGGYLPARRQKAEALQIP
QLSAFDALLKATGEGREVSTTMAFVRILNTLLKDKQIGKHVVPIVPDESRTFGMEGLFRQVGIWNQEGQKYVPEDHDQLM
FYKESQTGQVLQEGINEAGAMCDWIAAATSYSTHGVQMIPFYIYYSMFGIQRIGDLCWAAADMRSRGFLLGGTAGRTTLN
GEGLQHEDGHSHVFHSVIPNCISYDPTFQYELAVIMQDGLRRMYAEQEDVYYYLTVMNENYEHPEMPAGVEQDIVKGMYQ
FRKGVENSNAPRVQLLGSGTIFREVIAAAELLKKDWGVESDLWGCPSFTELAREGQAAERFNLLHPAEPQRESFVAQKLK
SARGPVIASTDYVRAFAEQIRPFVPRRYVVLGTDGFGRSDTREKLRHFFEVDRHWVTLAALKALADEGAISRDKVAEAIK
KYNLDPNKPNPMSV

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=884, Percent_Identity=62.10407239819, Blast_Score=1130, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 100518; Mature: 100387

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPEQILGASSANDADPQETHEWLDALQGVIAAEGSERAAFLIDKQIEYARVNGVTQP
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCCCC
FHAETQYINTIPVEQQARIPGDQDIEHRIRSYTRWNAMAMVLRANKHTNVGGHISSFASA
CCCCCHHEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHH
ATLYDVGYNHFWRAPSEQSGGDLVFVQGHSAPGVYSRAFLLGRLTPDQLDSFRQEVDGKG
HHHHHCCHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCC
ISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLDSRGLAKAGDRKVWAFLGDGET
CCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
DEPESLGAIGMAGREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVV
CCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEE
WGSKWDSLLARDTKGLLMKRMMDCVDGEYQTMKAKDGAYVREHFFNSPELKAMVADWSDD
ECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCCCEEEEECCCCC
DIWRLNRGGHDPHKIYAAYKAASEHKGQPTLILAKTIKGYGMGDAGQAMNVAHQQKKMPV
CEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCH
DAIRKFRDQFNLPVPDDKLDEVPYITFPEGSKELEYMRQARMNLGGYLPARRQKAEALQI
HHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
PQLSAFDALLKATGEGREVSTTMAFVRILNTLLKDKQIGKHVVPIVPDESRTFGMEGLFR
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
QVGIWNQEGQKYVPEDHDQLMFYKESQTGQVLQEGINEAGAMCDWIAAATSYSTHGVQMI
HHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
PFYIYYSMFGIQRIGDLCWAAADMRSRGFLLGGTAGRTTLNGEGLQHEDGHSHVFHSVIP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCCCCCCCCCHHHHHHHHH
NCISYDPTFQYELAVIMQDGLRRMYAEQEDVYYYLTVMNENYEHPEMPAGVEQDIVKGMY
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
QFRKGVENSNAPRVQLLGSGTIFREVIAAAELLKKDWGVESDLWGCPSFTELAREGQAAE
HHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHH
RFNLLHPAEPQRESFVAQKLKSARGPVIASTDYVRAFAEQIRPFVPRRYVVLGTDGFGRS
HHCCCCCCCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
DTREKLRHFFEVDRHWVTLAALKALADEGAISRDKVAEAIKKYNLDPNKPNPMSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SAVPEQILGASSANDADPQETHEWLDALQGVIAAEGSERAAFLIDKQIEYARVNGVTQP
CCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCCCC
FHAETQYINTIPVEQQARIPGDQDIEHRIRSYTRWNAMAMVLRANKHTNVGGHISSFASA
CCCCCHHEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHH
ATLYDVGYNHFWRAPSEQSGGDLVFVQGHSAPGVYSRAFLLGRLTPDQLDSFRQEVDGKG
HHHHHCCHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCC
ISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLDSRGLAKAGDRKVWAFLGDGET
CCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
DEPESLGAIGMAGREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVV
CCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEE
WGSKWDSLLARDTKGLLMKRMMDCVDGEYQTMKAKDGAYVREHFFNSPELKAMVADWSDD
ECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCCCEEEEECCCCC
DIWRLNRGGHDPHKIYAAYKAASEHKGQPTLILAKTIKGYGMGDAGQAMNVAHQQKKMPV
CEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCH
DAIRKFRDQFNLPVPDDKLDEVPYITFPEGSKELEYMRQARMNLGGYLPARRQKAEALQI
HHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
PQLSAFDALLKATGEGREVSTTMAFVRILNTLLKDKQIGKHVVPIVPDESRTFGMEGLFR
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
QVGIWNQEGQKYVPEDHDQLMFYKESQTGQVLQEGINEAGAMCDWIAAATSYSTHGVQMI
HHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
PFYIYYSMFGIQRIGDLCWAAADMRSRGFLLGGTAGRTTLNGEGLQHEDGHSHVFHSVIP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCCCCCCCCCHHHHHHHHH
NCISYDPTFQYELAVIMQDGLRRMYAEQEDVYYYLTVMNENYEHPEMPAGVEQDIVKGMY
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
QFRKGVENSNAPRVQLLGSGTIFREVIAAAELLKKDWGVESDLWGCPSFTELAREGQAAE
HHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHH
RFNLLHPAEPQRESFVAQKLKSARGPVIASTDYVRAFAEQIRPFVPRRYVVLGTDGFGRS
HHCCCCCCCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
DTREKLRHFFEVDRHWVTLAALKALADEGAISRDKVAEAIKKYNLDPNKPNPMSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]