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The map label for this gene is abcA [H]

Identifier: 73540423

GI number: 73540423

Start: 776022

End: 777416

Strand: Direct

Name: abcA [H]

Synonym: Reut_A0717

Alternate gene names: 73540423

Gene position: 776022-777416 (Clockwise)

Preceding gene: 73540422

Following gene: 73540424

Centisome position: 20.39

GC content: 57.13

Gene sequence:

>1395_bases
ATGTCCTCTGACTCCGTCATCCGCGTCAGCAATCTAGGCAAGCGGTACGAAATCTATGCGCAGCCCAAGGATCGCCTCAA
ACAAATGGTCATGCCGCGACTGAAGCGCATGATCGGCATGCATCCGCCCGAATATTTTCGCGAGTTCTGGGCGTTGCGTG
GCGTGAGCTTCGAAGTTCGCCGGGGCGAAACCGTTGCCATCATTGGCCAGAACGGCTCCGGAAAGTCGACATTGCTGCAG
TTGGTGTGCGGTACGCTGTTTCCGACCAATGGCGATATTCAGGTAAAGGGACGGATTGCCGCACTACTTGAACTCGGCGC
AGGATTTAATCCCGAATTCACCGGCGAGGAGAATATTTATCTGAGCGGCCTGCTTTATGGCATCTCGGAGGATGAGCTTC
GCAACCGCTTCGATTCTATCGTGGAATTTGCCGAAATCGGCGAATTCATCAGTCAGCCGGTCAAGACATACTCAAGCGGC
ATGTATGTGCGATTGGCATTTGCTATTGCCGCGCACGTGGATGCCGATATGCTCGTGGTGGATGAGGCATTGTCCGTGGG
CGACGTGCGGTTCACGCAGAAGTGCATGCGTTTTCTGCGCGAGTTCCAGAAGACGGGGACGCTGCTGTTCGTCAGCCACG
ATGTCGGCGCGGTGACCAGCCTTTGTTCGCGGGCGATTTGGCTGAACCAGGGCGTGCTGAAGATGGACGGCCCAGCAAAG
GAAACCGTGGAGGCCTATCTGGCGGAACAGCATGCGCTGGATCGTGGGCAACGTGGTGATGTGGTGCAGCTGGCCAAAGC
CCGAGAAAAAGTGGCTAAGCAGCCTGCGAAGGCCGCGAACCCGCCTGTGGTCGACGTCGTGGATCAGCGCTGGGAAGCCC
TGCGTGCCAATGGCTCGGGCACCCGCATCGAGGTCTTTGAGTTCATGCCGGATTCATCGGAGAGCGAGTTTGGCGCCCGA
GGCGCCACGATAGAACGCGTGGCATTGCGCAACGAGGCGGGTGAGGATTTGCCCATCGTGCAAGGTGGAGAACTGGTGGA
TCTGTACATCGAATCGCGTTCGCATCAAGCGTTGGCCGGCCTTATCTTTGGCTTCTATCTGAAAGATCGCCTGGGTCAAC
GCCTGTTTGGCGACAACACGTTCATGACCTACGCTGATCGCGAGGTTCGATCACAGGCCGGCGATACCCATATCGCGAGG
TTCCGATTCCGGATGCCAATCATGCCAGTCGGCGCTTATTCATTCGACGTCGCCATTGCGACCGGCAATCAGCACGATCA
CACGCAGCAACACTGGATCCACGACGCTCTTTCCATGCGTGCGGTTGACAGCACGATGCGGCATGGGCTTGTGGGAATTC
CGATGCTCGAAATCGCAATTTCTAAGGAAGGATAG

Upstream 100 bases:

>100_bases
AGTATTGATTGGATGGGCTGGGTTCTCTACCTGGTGATTGCCTATTGCGTTGCATGGCTTGGCCTGGTGTGGTTCCAGAA
GACGCGAAAGGGGTTTGCCG

Downstream 100 bases:

>100_bases
CCAGTGTTGGACTTTACGGGTGAGCGTTTCATTCCCACGGAAGGTGGCGTTGTTCACTACGAGCATATGCACCGTTATGC
TTGGTGTCTGCAGTTTGTGG

Product: ABC transporter related

Products: ADP; phosphate; arabinose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSSDSVIRVSNLGKRYEIYAQPKDRLKQMVMPRLKRMIGMHPPEYFREFWALRGVSFEVRRGETVAIIGQNGSGKSTLLQ
LVCGTLFPTNGDIQVKGRIAALLELGAGFNPEFTGEENIYLSGLLYGISEDELRNRFDSIVEFAEIGEFISQPVKTYSSG
MYVRLAFAIAAHVDADMLVVDEALSVGDVRFTQKCMRFLREFQKTGTLLFVSHDVGAVTSLCSRAIWLNQGVLKMDGPAK
ETVEAYLAEQHALDRGQRGDVVQLAKAREKVAKQPAKAANPPVVDVVDQRWEALRANGSGTRIEVFEFMPDSSESEFGAR
GATIERVALRNEAGEDLPIVQGGELVDLYIESRSHQALAGLIFGFYLKDRLGQRLFGDNTFMTYADREVRSQAGDTHIAR
FRFRMPIMPVGAYSFDVAIATGNQHDHTQQHWIHDALSMRAVDSTMRHGLVGIPMLEIAISKEG

Sequences:

>Translated_464_residues
MSSDSVIRVSNLGKRYEIYAQPKDRLKQMVMPRLKRMIGMHPPEYFREFWALRGVSFEVRRGETVAIIGQNGSGKSTLLQ
LVCGTLFPTNGDIQVKGRIAALLELGAGFNPEFTGEENIYLSGLLYGISEDELRNRFDSIVEFAEIGEFISQPVKTYSSG
MYVRLAFAIAAHVDADMLVVDEALSVGDVRFTQKCMRFLREFQKTGTLLFVSHDVGAVTSLCSRAIWLNQGVLKMDGPAK
ETVEAYLAEQHALDRGQRGDVVQLAKAREKVAKQPAKAANPPVVDVVDQRWEALRANGSGTRIEVFEFMPDSSESEFGAR
GATIERVALRNEAGEDLPIVQGGELVDLYIESRSHQALAGLIFGFYLKDRLGQRLFGDNTFMTYADREVRSQAGDTHIAR
FRFRMPIMPVGAYSFDVAIATGNQHDHTQQHWIHDALSMRAVDSTMRHGLVGIPMLEIAISKEG
>Mature_463_residues
SSDSVIRVSNLGKRYEIYAQPKDRLKQMVMPRLKRMIGMHPPEYFREFWALRGVSFEVRRGETVAIIGQNGSGKSTLLQL
VCGTLFPTNGDIQVKGRIAALLELGAGFNPEFTGEENIYLSGLLYGISEDELRNRFDSIVEFAEIGEFISQPVKTYSSGM
YVRLAFAIAAHVDADMLVVDEALSVGDVRFTQKCMRFLREFQKTGTLLFVSHDVGAVTSLCSRAIWLNQGVLKMDGPAKE
TVEAYLAEQHALDRGQRGDVVQLAKAREKVAKQPAKAANPPVVDVVDQRWEALRANGSGTRIEVFEFMPDSSESEFGARG
ATIERVALRNEAGEDLPIVQGGELVDLYIESRSHQALAGLIFGFYLKDRLGQRLFGDNTFMTYADREVRSQAGDTHIARF
RFRMPIMPVGAYSFDVAIATGNQHDHTQQHWIHDALSMRAVDSTMRHGLVGIPMLEIAISKEG

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=203, Percent_Identity=27.0935960591133, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI27477115, Length=245, Percent_Identity=25.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI27881501, Length=241, Percent_Identity=21.5767634854772, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI30795238, Length=241, Percent_Identity=21.5767634854772, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI27436953, Length=299, Percent_Identity=22.4080267558528, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI6005701, Length=197, Percent_Identity=27.4111675126904, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI90421313, Length=156, Percent_Identity=30.1282051282051, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1788210, Length=190, Percent_Identity=30.5263157894737, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786703, Length=205, Percent_Identity=30.2439024390244, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787758, Length=203, Percent_Identity=26.6009852216749, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1789891, Length=202, Percent_Identity=27.7227722772277, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788761, Length=265, Percent_Identity=23.3962264150943, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789873, Length=199, Percent_Identity=27.1356783919598, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48995001, Length=243, Percent_Identity=25.5144032921811, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082267, Length=205, Percent_Identity=25.3658536585366, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994943, Length=298, Percent_Identity=25.503355704698, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081709, Length=198, Percent_Identity=25.7575757575758, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786253, Length=199, Percent_Identity=28.1407035175879, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787712, Length=201, Percent_Identity=25.3731343283582, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786319, Length=216, Percent_Identity=24.537037037037, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87081834, Length=182, Percent_Identity=30.2197802197802, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1786398, Length=204, Percent_Identity=25.9803921568627, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17565586, Length=215, Percent_Identity=26.9767441860465, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71983523, Length=237, Percent_Identity=24.8945147679325, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=237, Percent_Identity=24.8945147679325, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=237, Percent_Identity=24.8945147679325, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321121, Length=191, Percent_Identity=27.7486910994764, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221500365, Length=325, Percent_Identity=27.0769230769231, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007184, Length=325, Percent_Identity=27.0769230769231, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 51660; Mature: 51529

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDSVIRVSNLGKRYEIYAQPKDRLKQMVMPRLKRMIGMHPPEYFREFWALRGVSFEVR
CCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEE
RGETVAIIGQNGSGKSTLLQLVCGTLFPTNGDIQVKGRIAALLELGAGFNPEFTGEENIY
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHCCCCCCCCCCCCCEE
LSGLLYGISEDELRNRFDSIVEFAEIGEFISQPVKTYSSGMYVRLAFAIAAHVDADMLVV
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCEEEE
DEALSVGDVRFTQKCMRFLREFQKTGTLLFVSHDVGAVTSLCSRAIWLNQGVLKMDGPAK
HHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCEEEECCCHH
ETVEAYLAEQHALDRGQRGDVVQLAKAREKVAKQPAKAANPPVVDVVDQRWEALRANGSG
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCC
TRIEVFEFMPDSSESEFGARGATIERVALRNEAGEDLPIVQGGELVDLYIESRSHQALAG
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEECCCCEEEEEEECCCHHHHHH
LIFGFYLKDRLGQRLFGDNTFMTYADREVRSQAGDTHIARFRFRMPIMPVGAYSFDVAIA
HHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCEEEEEEEECCCEECCCEEEEEEEE
TGNQHDHTQQHWIHDALSMRAVDSTMRHGLVGIPMLEIAISKEG
ECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
SSDSVIRVSNLGKRYEIYAQPKDRLKQMVMPRLKRMIGMHPPEYFREFWALRGVSFEVR
CCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEE
RGETVAIIGQNGSGKSTLLQLVCGTLFPTNGDIQVKGRIAALLELGAGFNPEFTGEENIY
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHCCCCCCCCCCCCCEE
LSGLLYGISEDELRNRFDSIVEFAEIGEFISQPVKTYSSGMYVRLAFAIAAHVDADMLVV
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCEEEE
DEALSVGDVRFTQKCMRFLREFQKTGTLLFVSHDVGAVTSLCSRAIWLNQGVLKMDGPAK
HHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCEEEECCCHH
ETVEAYLAEQHALDRGQRGDVVQLAKAREKVAKQPAKAANPPVVDVVDQRWEALRANGSG
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCC
TRIEVFEFMPDSSESEFGARGATIERVALRNEAGEDLPIVQGGELVDLYIESRSHQALAG
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEECCCCEEEEEEECCCHHHHHH
LIFGFYLKDRLGQRLFGDNTFMTYADREVRSQAGDTHIARFRFRMPIMPVGAYSFDVAIA
HHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCEEEEEEEECCCEECCCEEEEEEEE
TGNQHDHTQQHWIHDALSMRAVDSTMRHGLVGIPMLEIAISKEG
ECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arabinose [Periplasm]; H2O [C]

Specific reaction: ATP + arabinose [Periplasm] + H2O = ADP + phosphate + arabinose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]