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The map label for this gene is ychM [C]

Identifier: 73540396

GI number: 73540396

Start: 744202

End: 745953

Strand: Reverse

Name: ychM [C]

Synonym: Reut_A0690

Alternate gene names: 73540396

Gene position: 745953-744202 (Counterclockwise)

Preceding gene: 73540399

Following gene: 73540381

Centisome position: 19.6

GC content: 65.24

Gene sequence:

>1752_bases
GTGCCCGACCAACCCTATCGTCCATCAGCCGGAGAGGCATCGGAGGCCAGGCCCGCAAAGGGCTGGCTGCGCTGGCTGCC
CGGCGTGCAGACGCTGCGACAGTACGAGGCAGCATGGCTGCCTCGTGACGTGGCGGCCGGCCTCGTACTGACTACCATGC
TGGTGCCGGTCGGCATTGCCTATGCGGAGGCATCCGGCGTCCCTGGCATCTACGGCTTGTACGCCACCATCATTCCGCTG
CTGGCCTACGCGCTGTTCGGTCCCAGCCGGATACTGGTGCTGGGACCGGACTCGGCACTGGCCGCGCCGATCCTTGCCGT
GGTGATCCAGCTGTCGGCTGGCGATCCGGCCCGCGCGATCGCCGTGGCAAGCATGATGGCGGTGGTATCGGGCGCGGTCT
GTATCCTGGCCGGGCTGCTGCGCCTGGGGTTCGTTACCGAACTGCTGTCCAAGCCGATCCGATACGGCTACATGAATGGC
ATTGCATTGACCGTCCTGATCAGCCAGCTTCCAAAGTTGTTTGGCATCTCCATCGAGGACGCCGGACCCCTGCGGGAATT
GTGGGACCTGATCCAAGCGCTGGGAGACGGCAAGGCCAACTGGTACAGCGCGGCGGTCGGAGGCAGCGCGCTGGCCCTGA
TCCTGCTGCTAAAGCGCTTCGAACGCGTGCCGGGCATTCTGATCGCCGTGATCCTGGCGACACTGGCTGTCGCCTGGTTC
GGCCTGCAGGACCACGGTGTCAAAGTGCTGGGCAAGATGCCGCAGGGGCTGCCCGTCTTCCACTTGCCATGGCTGAGCGG
CGTGGATATCGCCAAGGTGGTAGCCGGCGGCTTCGCCGTCGCGATGGTGGCATTCGCCGACACCAGCGTGCTGTCGCGAA
CCTATGCGGCGCGAATGAAGCGACCGGTCGATCCCAATCAGGAAATGGTCGGGCTTGGCGCCGCCAATCTCGCAGCGGGG
CTGTTCCAGGGCTTTCCGATCAGCAGCAGCTCATCACGCACGCCGGTTGCGGAAGCGGCGGGCGCCAAAACCCAGCTCAC
GGGCGTGATCGGCGCGCTGGCCGTAGCCGCCCTGCTGCTGTTCGCGCCGAACCTGATGCGCTATCTGCCGAACAGCGCGC
TGGCGGCGGTGGTCATCGCCTCGGCGCTCGGGCTGTTCGAGTTCGCGGACCTGAGGCGGATCTTCCGCATCCAGCAATGG
GAGTTCTGGCTTTCGATGGCGTGCTTTGCCGGCGTCGCCGTGTTCGGTGCGATTCCGGGCATCGGCCTGGCCGTGGCCCT
GGCCGTGATTGAATTCCTGTGGGACGGCTGGCGCCCGCACTACGCCATTCTCGGGCGTGCTGACGGCGTGCGTGGCTATC
ACGACGTGGAGCGCTATCCGAACGCGCGACGCGTGCCCGGCCTGGTGCTGTTCCGCTGGGATGCGCCGCTGTTCTTTGCG
AACGCGGAGCTGTTCCAGACATGTGTCATGCAAGCCGTCGAAGGTTCACCCACCGAGGTGCGACGCGTGGTAGTGGCAGC
CGAGCCGGTGACCAGCGTCGATGTGACCTCGGCGGATATGCTGCGCGAACTCGACAAAACGCTGGACGAACGCGGCATCG
AATTGCACTTCGCCGAGATGAAGGACCCGGTCAAGGACAAGCTCAAGCGCTTCGAACTGTTTGACCACCTCGGGCAGGAT
GTCTTCCACCCGACGGTTGGCGCGGCGGTGGATGACTACCTGAGCGATCACAATGTGGACTGGAAGGCGTGA

Upstream 100 bases:

>100_bases
GGTGCCTTTGTCGCAAGTGCCATGCCCGCAAGCTGTGCGTCTTGCTATGCTGGGTATCGTCCACATCCGATTCACGACGT
ACGGCCAGGGGAGCAACCAC

Downstream 100 bases:

>100_bases
TGACGAAGCAGCGGCCGCATGCGTAAAAAACGCCGGCCTGCCATCTGGCAGGCCGGCGCATCGCTACGTCGGCAGTGGTC
GCGTGGTCGTGAATTTAGCT

Product: sulphate anion transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MPDQPYRPSAGEASEARPAKGWLRWLPGVQTLRQYEAAWLPRDVAAGLVLTTMLVPVGIAYAEASGVPGIYGLYATIIPL
LAYALFGPSRILVLGPDSALAAPILAVVIQLSAGDPARAIAVASMMAVVSGAVCILAGLLRLGFVTELLSKPIRYGYMNG
IALTVLISQLPKLFGISIEDAGPLRELWDLIQALGDGKANWYSAAVGGSALALILLLKRFERVPGILIAVILATLAVAWF
GLQDHGVKVLGKMPQGLPVFHLPWLSGVDIAKVVAGGFAVAMVAFADTSVLSRTYAARMKRPVDPNQEMVGLGAANLAAG
LFQGFPISSSSSRTPVAEAAGAKTQLTGVIGALAVAALLLFAPNLMRYLPNSALAAVVIASALGLFEFADLRRIFRIQQW
EFWLSMACFAGVAVFGAIPGIGLAVALAVIEFLWDGWRPHYAILGRADGVRGYHDVERYPNARRVPGLVLFRWDAPLFFA
NAELFQTCVMQAVEGSPTEVRRVVVAAEPVTSVDVTSADMLRELDKTLDERGIELHFAEMKDPVKDKLKRFELFDHLGQD
VFHPTVGAAVDDYLSDHNVDWKA

Sequences:

>Translated_583_residues
MPDQPYRPSAGEASEARPAKGWLRWLPGVQTLRQYEAAWLPRDVAAGLVLTTMLVPVGIAYAEASGVPGIYGLYATIIPL
LAYALFGPSRILVLGPDSALAAPILAVVIQLSAGDPARAIAVASMMAVVSGAVCILAGLLRLGFVTELLSKPIRYGYMNG
IALTVLISQLPKLFGISIEDAGPLRELWDLIQALGDGKANWYSAAVGGSALALILLLKRFERVPGILIAVILATLAVAWF
GLQDHGVKVLGKMPQGLPVFHLPWLSGVDIAKVVAGGFAVAMVAFADTSVLSRTYAARMKRPVDPNQEMVGLGAANLAAG
LFQGFPISSSSSRTPVAEAAGAKTQLTGVIGALAVAALLLFAPNLMRYLPNSALAAVVIASALGLFEFADLRRIFRIQQW
EFWLSMACFAGVAVFGAIPGIGLAVALAVIEFLWDGWRPHYAILGRADGVRGYHDVERYPNARRVPGLVLFRWDAPLFFA
NAELFQTCVMQAVEGSPTEVRRVVVAAEPVTSVDVTSADMLRELDKTLDERGIELHFAEMKDPVKDKLKRFELFDHLGQD
VFHPTVGAAVDDYLSDHNVDWKA
>Mature_582_residues
PDQPYRPSAGEASEARPAKGWLRWLPGVQTLRQYEAAWLPRDVAAGLVLTTMLVPVGIAYAEASGVPGIYGLYATIIPLL
AYALFGPSRILVLGPDSALAAPILAVVIQLSAGDPARAIAVASMMAVVSGAVCILAGLLRLGFVTELLSKPIRYGYMNGI
ALTVLISQLPKLFGISIEDAGPLRELWDLIQALGDGKANWYSAAVGGSALALILLLKRFERVPGILIAVILATLAVAWFG
LQDHGVKVLGKMPQGLPVFHLPWLSGVDIAKVVAGGFAVAMVAFADTSVLSRTYAARMKRPVDPNQEMVGLGAANLAAGL
FQGFPISSSSSRTPVAEAAGAKTQLTGVIGALAVAALLLFAPNLMRYLPNSALAAVVIASALGLFEFADLRRIFRIQQWE
FWLSMACFAGVAVFGAIPGIGLAVALAVIEFLWDGWRPHYAILGRADGVRGYHDVERYPNARRVPGLVLFRWDAPLFFAN
AELFQTCVMQAVEGSPTEVRRVVVAAEPVTSVDVTSADMLRELDKTLDERGIELHFAEMKDPVKDKLKRFELFDHLGQDV
FHPTVGAAVDDYLSDHNVDWKA

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=511, Percent_Identity=28.3757338551859, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI39752683, Length=511, Percent_Identity=28.3757338551859, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI94721259, Length=508, Percent_Identity=30.7086614173228, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI94721255, Length=508, Percent_Identity=30.511811023622, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI94721253, Length=508, Percent_Identity=30.511811023622, Blast_Score=203, Evalue=4e-52,
Organism=Homo sapiens, GI94721257, Length=508, Percent_Identity=30.7086614173228, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI4557535, Length=564, Percent_Identity=26.7730496453901, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI269784651, Length=510, Percent_Identity=26.6666666666667, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI4505697, Length=515, Percent_Identity=27.1844660194175, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI45827802, Length=460, Percent_Identity=28.9130434782609, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI100913030, Length=629, Percent_Identity=24.483306836248, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI47131207, Length=610, Percent_Identity=27.3770491803279, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI20336272, Length=610, Percent_Identity=27.3770491803279, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI262206105, Length=599, Percent_Identity=25.3756260434057, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI262206075, Length=599, Percent_Identity=25.3756260434057, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI262206069, Length=599, Percent_Identity=25.3756260434057, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI262206063, Length=599, Percent_Identity=25.3756260434057, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI16418413, Length=506, Percent_Identity=24.1106719367589, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI217272867, Length=506, Percent_Identity=24.1106719367589, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI16306483, Length=611, Percent_Identity=22.2585924713584, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI20336282, Length=607, Percent_Identity=22.2405271828666, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI65506789, Length=376, Percent_Identity=29.7872340425532, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI16418457, Length=495, Percent_Identity=21.8181818181818, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI301601599, Length=495, Percent_Identity=21.8181818181818, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI45827804, Length=266, Percent_Identity=28.1954887218045, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI301601602, Length=208, Percent_Identity=22.1153846153846, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081859, Length=569, Percent_Identity=25.8347978910369, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17562578, Length=633, Percent_Identity=27.172195892575, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI86564196, Length=618, Percent_Identity=26.0517799352751, Blast_Score=191, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17566848, Length=618, Percent_Identity=25.2427184466019, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17551690, Length=607, Percent_Identity=24.0527182866557, Blast_Score=166, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI86565215, Length=583, Percent_Identity=23.4991423670669, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI86564876, Length=396, Percent_Identity=25.2525252525253, Blast_Score=135, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI193203292, Length=542, Percent_Identity=24.9077490774908, Blast_Score=126, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI86565213, Length=273, Percent_Identity=26.3736263736264, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI86565209, Length=247, Percent_Identity=27.1255060728745, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI86565211, Length=247, Percent_Identity=27.1255060728745, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325260, Length=587, Percent_Identity=21.1243611584327, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6323121, Length=475, Percent_Identity=24.4210526315789, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6319771, Length=479, Percent_Identity=23.5908141962422, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24666186, Length=542, Percent_Identity=26.1992619926199, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24649801, Length=578, Percent_Identity=24.3944636678201, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI85815873, Length=560, Percent_Identity=25.8928571428571, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21358633, Length=613, Percent_Identity=23.9804241435563, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI19922482, Length=526, Percent_Identity=24.5247148288973, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24651449, Length=576, Percent_Identity=22.2222222222222, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24647160, Length=465, Percent_Identity=23.010752688172, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI21355087, Length=465, Percent_Identity=23.010752688172, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21358229, Length=587, Percent_Identity=21.6354344122658, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24663084, Length=606, Percent_Identity=21.6171617161716, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357695, Length=606, Percent_Identity=21.6171617161716, Blast_Score=97, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 62487; Mature: 62356

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDQPYRPSAGEASEARPAKGWLRWLPGVQTLRQYEAAWLPRDVAAGLVLTTMLVPVGIA
CCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
YAEASGVPGIYGLYATIIPLLAYALFGPSRILVLGPDSALAAPILAVVIQLSAGDPARAI
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHH
AVASMMAVVSGAVCILAGLLRLGFVTELLSKPIRYGYMNGIALTVLISQLPKLFGISIED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AGPLRELWDLIQALGDGKANWYSAAVGGSALALILLLKRFERVPGILIAVILATLAVAWF
CCCHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GLQDHGVKVLGKMPQGLPVFHLPWLSGVDIAKVVAGGFAVAMVAFADTSVLSRTYAARMK
CCCCCCHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPVDPNQEMVGLGAANLAAGLFQGFPISSSSSRTPVAEAAGAKTQLTGVIGALAVAALLL
CCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
FAPNLMRYLPNSALAAVVIASALGLFEFADLRRIFRIQQWEFWLSMACFAGVAVFGAIPG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IGLAVALAVIEFLWDGWRPHYAILGRADGVRGYHDVERYPNARRVPGLVLFRWDAPLFFA
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCEEEEEECCCEEEC
NAELFQTCVMQAVEGSPTEVRRVVVAAEPVTSVDVTSADMLRELDKTLDERGIELHFAEM
CHHHHHHHHHHHHCCCHHHHHEEHEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHH
KDPVKDKLKRFELFDHLGQDVFHPTVGAAVDDYLSDHNVDWKA
CCHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PDQPYRPSAGEASEARPAKGWLRWLPGVQTLRQYEAAWLPRDVAAGLVLTTMLVPVGIA
CCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
YAEASGVPGIYGLYATIIPLLAYALFGPSRILVLGPDSALAAPILAVVIQLSAGDPARAI
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHH
AVASMMAVVSGAVCILAGLLRLGFVTELLSKPIRYGYMNGIALTVLISQLPKLFGISIED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AGPLRELWDLIQALGDGKANWYSAAVGGSALALILLLKRFERVPGILIAVILATLAVAWF
CCCHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GLQDHGVKVLGKMPQGLPVFHLPWLSGVDIAKVVAGGFAVAMVAFADTSVLSRTYAARMK
CCCCCCHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPVDPNQEMVGLGAANLAAGLFQGFPISSSSSRTPVAEAAGAKTQLTGVIGALAVAALLL
CCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
FAPNLMRYLPNSALAAVVIASALGLFEFADLRRIFRIQQWEFWLSMACFAGVAVFGAIPG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IGLAVALAVIEFLWDGWRPHYAILGRADGVRGYHDVERYPNARRVPGLVLFRWDAPLFFA
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCEEEEEECCCEEEC
NAELFQTCVMQAVEGSPTEVRRVVVAAEPVTSVDVTSADMLRELDKTLDERGIELHFAEM
CHHHHHHHHHHHHCCCHHHHHEEHEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHH
KDPVKDKLKRFELFDHLGQDVFHPTVGAAVDDYLSDHNVDWKA
CCHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]