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The map label for this gene is ackA [H]

Identifier: 73540331

GI number: 73540331

Start: 672157

End: 673380

Strand: Reverse

Name: ackA [H]

Synonym: Reut_A0625

Alternate gene names: 73540331

Gene position: 673380-672157 (Counterclockwise)

Preceding gene: 73540332

Following gene: 73540328

Centisome position: 17.69

GC content: 68.79

Gene sequence:

>1224_bases
GTGAGTGCCACCCATCCCGTCGTCCTGGTCGTCAATGCCGGCTCTTCCAGCGTCAAGGTTTCCGTCTACACCGTGCCGGA
AGCCGCGCATGACAACGCAGATATCAACCCCGTACTGAGCGCGCACGGGCAGATCGAAAGCATCGGCGTCGCGCCGCGGC
TGCGCGCGAGCATGGCCGATGGCCATGTCGTCGCCGACGAATCGTTTCCCGTCGCGCAGGTCGCCGACCACGACGCAGCC
TTCCGCCTGATACGCCTGGTGCTGAGCGTGGGGCTGCGCGACAACCCGCCGGTCGCCATCGGCCACCGCGTGGTCCACGG
CGGCAGCGACTTCGCGCAGGCCGTGCGCATCGACGACGACGTGATCTCGCGCCTCGAGGCGCTGATCCCGCTGGCGCCGC
TGCACCAGCCCCATAACCTCACTGCGATCCGTGCGGTGCGCAAGGCCGCCCCTGACCTGCTGCAAGTCGCCTGTTTCGAC
ACGGCCTTCCATGCCGGGCACGACATGCTTGCCCAGTTGATAGCGCTGCCCTACGAGTACTACGAGCGGGGCATCCGGCG
CTACGGCTTCCACGGGCTGTCCTACGAGTACATCGCCCGGCGCCTGGGCCAGGTGGCACCTGACGTCGCCGCGGGCCGCG
TGATCGTGGCCCACCTGGGCAACGGCGCAAGCCTGTGCGCCATGCGCGATGGCCGCAGCGTGGAAAGCACCATGGGACTG
ACGGCGCTAGACGGCATGCCGATGGGCACGCGCTGCGGCTCCATCGACCCGGGCGCGGTGCTGTGGCTGGCGCAGCAGGG
CATGACCGCCGACGCGATCCAGACGATGTTGTATGGCGCTTCCGGCCTGAAGGGACTATCAGGGGTCAGCAGCGACATGC
GCGCGCTTCTGGCGAGCGAAGAGCCGCGCGCACGGCTCGCGGTGGACTTCTACGCCTACCGCGCGGCGCAGGAGATCGGC
AAGCTGGCCGTCACGCTCGGCGGCCTGGACACGCTGGTGTTCACCGCCGGCATCGGCGCCAATTCGCCGCCGGTGCGCGC
ACGCATCTGCGCACACCTGACGGACCTGTTCGGCATCAGCCTGGACAACGCGGCCAACAACGACAACAGCCAGCGCGTGA
GCAGCGACGCCAGCCGCGTGCCGGTGCTGGTGCTGCCCACCGACGAGGAAGGCATGATCGCGCTGAGCACCGCGCGCATC
CTGCGCGAAAGCGGCAAGCTGTAA

Upstream 100 bases:

>100_bases
GCTGCGCCATCGCGGTCCTGCTCGCGCATGCGCGCCGCAGCGCCGAAGCCGCCGTACCGGTCTGAGCTGCCCCCCCCACC
TTATGCGGAGTGCATCGAGC

Downstream 100 bases:

>100_bases
GGCCGGCGCGGCGCTCGCCGCGCGTCAGGCTTCCAGGTAGTGCGCGCGCAGCTGCTCCACGTCGACGTCCAGCCCGTCGC
GCAGGAAGCCATTCATGCTG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSATHPVVLVVNAGSSSVKVSVYTVPEAAHDNADINPVLSAHGQIESIGVAPRLRASMADGHVVADESFPVAQVADHDAA
FRLIRLVLSVGLRDNPPVAIGHRVVHGGSDFAQAVRIDDDVISRLEALIPLAPLHQPHNLTAIRAVRKAAPDLLQVACFD
TAFHAGHDMLAQLIALPYEYYERGIRRYGFHGLSYEYIARRLGQVAPDVAAGRVIVAHLGNGASLCAMRDGRSVESTMGL
TALDGMPMGTRCGSIDPGAVLWLAQQGMTADAIQTMLYGASGLKGLSGVSSDMRALLASEEPRARLAVDFYAYRAAQEIG
KLAVTLGGLDTLVFTAGIGANSPPVRARICAHLTDLFGISLDNAANNDNSQRVSSDASRVPVLVLPTDEEGMIALSTARI
LRESGKL

Sequences:

>Translated_407_residues
MSATHPVVLVVNAGSSSVKVSVYTVPEAAHDNADINPVLSAHGQIESIGVAPRLRASMADGHVVADESFPVAQVADHDAA
FRLIRLVLSVGLRDNPPVAIGHRVVHGGSDFAQAVRIDDDVISRLEALIPLAPLHQPHNLTAIRAVRKAAPDLLQVACFD
TAFHAGHDMLAQLIALPYEYYERGIRRYGFHGLSYEYIARRLGQVAPDVAAGRVIVAHLGNGASLCAMRDGRSVESTMGL
TALDGMPMGTRCGSIDPGAVLWLAQQGMTADAIQTMLYGASGLKGLSGVSSDMRALLASEEPRARLAVDFYAYRAAQEIG
KLAVTLGGLDTLVFTAGIGANSPPVRARICAHLTDLFGISLDNAANNDNSQRVSSDASRVPVLVLPTDEEGMIALSTARI
LRESGKL
>Mature_406_residues
SATHPVVLVVNAGSSSVKVSVYTVPEAAHDNADINPVLSAHGQIESIGVAPRLRASMADGHVVADESFPVAQVADHDAAF
RLIRLVLSVGLRDNPPVAIGHRVVHGGSDFAQAVRIDDDVISRLEALIPLAPLHQPHNLTAIRAVRKAAPDLLQVACFDT
AFHAGHDMLAQLIALPYEYYERGIRRYGFHGLSYEYIARRLGQVAPDVAAGRVIVAHLGNGASLCAMRDGRSVESTMGLT
ALDGMPMGTRCGSIDPGAVLWLAQQGMTADAIQTMLYGASGLKGLSGVSSDMRALLASEEPRARLAVDFYAYRAAQEIGK
LAVTLGGLDTLVFTAGIGANSPPVRARICAHLTDLFGISLDNAANNDNSQRVSSDASRVPVLVLPTDEEGMIALSTARIL
RESGKL

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=402, Percent_Identity=39.5522388059701, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1788633, Length=412, Percent_Identity=36.8932038834951, Blast_Score=207, Evalue=7e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43015; Mature: 42883

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATHPVVLVVNAGSSSVKVSVYTVPEAAHDNADINPVLSAHGQIESIGVAPRLRASMAD
CCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCHHHHCCCCEEECCCCHHHHHHCCC
GHVVADESFPVAQVADHDAAFRLIRLVLSVGLRDNPPVAIGHRVVHGGSDFAQAVRIDDD
CEEEECCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCEEECCEEEECCCHHHHHHCCCHH
VISRLEALIPLAPLHQPHNLTAIRAVRKAAPDLLQVACFDTAFHAGHDMLAQLIALPYEY
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
YERGIRRYGFHGLSYEYIARRLGQVAPDVAAGRVIVAHLGNGASLCAMRDGRSVESTMGL
HHHHHHHHCCCCCCHHHHHHHHHHCCCCHHCCCEEEEECCCCCEEEEECCCCCHHHHCCE
TALDGMPMGTRCGSIDPGAVLWLAQQGMTADAIQTMLYGASGLKGLSGVSSDMRALLASE
EEECCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCC
EPRARLAVDFYAYRAAQEIGKLAVTLGGLDTLVFTAGIGANSPPVRARICAHLTDLFGIS
CCCCEEEHHHHHHHHHHHHHHHEEECCCHHEEHEEECCCCCCCCHHHHHHHHHHHHHCCE
LDNAANNDNSQRVSSDASRVPVLVLPTDEEGMIALSTARILRESGKL
ECCCCCCCCHHHHCCCCCCCCEEEEECCCCCEEEHHHHHHHHHCCCC
>Mature Secondary Structure 
SATHPVVLVVNAGSSSVKVSVYTVPEAAHDNADINPVLSAHGQIESIGVAPRLRASMAD
CCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCHHHHCCCCEEECCCCHHHHHHCCC
GHVVADESFPVAQVADHDAAFRLIRLVLSVGLRDNPPVAIGHRVVHGGSDFAQAVRIDDD
CEEEECCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCEEECCEEEECCCHHHHHHCCCHH
VISRLEALIPLAPLHQPHNLTAIRAVRKAAPDLLQVACFDTAFHAGHDMLAQLIALPYEY
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
YERGIRRYGFHGLSYEYIARRLGQVAPDVAAGRVIVAHLGNGASLCAMRDGRSVESTMGL
HHHHHHHHCCCCCCHHHHHHHHHHCCCCHHCCCEEEEECCCCCEEEEECCCCCHHHHCCE
TALDGMPMGTRCGSIDPGAVLWLAQQGMTADAIQTMLYGASGLKGLSGVSSDMRALLASE
EEECCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCC
EPRARLAVDFYAYRAAQEIGKLAVTLGGLDTLVFTAGIGANSPPVRARICAHLTDLFGIS
CCCCEEEHHHHHHHHHHHHHHHEEECCCHHEEHEEECCCCCCCCHHHHHHHHHHHHHCCE
LDNAANNDNSQRVSSDASRVPVLVLPTDEEGMIALSTARILRESGKL
ECCCCCCCCHHHHCCCCCCCCEEEEECCCCCEEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA