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The map label for this gene is mdtA [H]

Identifier: 73540278

GI number: 73540278

Start: 624031

End: 625527

Strand: Reverse

Name: mdtA [H]

Synonym: Reut_A0572

Alternate gene names: 73540278

Gene position: 625527-624031 (Counterclockwise)

Preceding gene: 73540281

Following gene: 73540277

Centisome position: 16.43

GC content: 70.01

Gene sequence:

>1497_bases
ATGCCCAACCCCGAACAAGGCCAACAACAACCTATCCCGCCGTCCCGCCCGCCGGAGGTCCCCGGCCCGGCCGGTTCGCC
ACGGCGCAAGCTGATCGCCGCGGCCCTCGTCGTACTGCTTGCCGGCGGCGGCTGGTACTGGTACAGCCATCGCGGCGCCG
GTGCGGACGCACAGGGGACACAGGGCGCGCGCGGGCCCGGCGGGCCGGGGGGCGCAAGTGGCCCGGGCGCCGGTGGCCGC
GGCGGGCCGGGCGGCCCCGGTGCCCCGCGCTCACCGGTGGTCGTGTCCACGGTCGCGCAGCGCGACATGGACGTGACCCT
GAACGGCCTGGGCAACGTCACACCCGTGTCCAACGTCACCGTGCGCGCCCAGGTGTCGGGGCCGCTGCTCAAGGTGCTGT
TCAAGGAAGGCCAGATGGTCAAGGCCGGCGACGTGCTCGCGGAAATCGACCCGCGTCCGTTCCAGGCCGCGTTCGACCAG
GCCGTGGGCCAGCTCGCGCGCGACCAGGCGCTGCTGCAGAACGCACGGCTGGACCAGAAGCGCTACCGCACGCTGCTGCA
GCAGGATTCGATTTCCAGCCAGCAGGTCGATACGCAGGATGCGCTGGTGCGCCAGTATGAAGGCGTGGTCAAGACCGACC
AGGGCAATGTGGACAATGCGCGGTTGCAGCTCGGCTACACCAAGGTCGTGGCGCCGGTGTCGGGCCGCATCGGCCTGCGC
CAGGTGGATCCCGGCAATATCGTCAATACGTCGGATACCAACGGCATTGCGCTGATCACGCAAATCCAGCCGATTGCCGT
GCTCTACACCATTCCCGAGGACAGCCTGCCCGCTGTGCTGAAAAAGCTCAATTCGGGCGAGAAAATGCCGGTGCAGGCCT
GGGACCGCCAGATGCGCAACCAGCTTGGCGACGGCACGCTGCTGACCACCGACAACCAGATCGACACCACCACCGGCACG
GTCAAGATGAAGGCCATCTTCCCGAACGCCGACGGCATGCTGTTCCCTAACCAGTTCGTCAATGTGCGCACGCGCGTGGA
CACGCTCAAGGACGCGACCGTGATCCCGGTCGCGGCCGTGCAGCGCGGACAGCAAGGCACCTTCGTCTACGTCGTCGACG
ACAGCAGCAAGGTCAGGGTGCAGGTCGTCACGCTCGGTCCCAGCGACGGCAACCGTACCGCTGTGCTCAAGGGCGTGGAG
CCCGGCCAGCGCGTGGTAGTGGACGGCGCCGATCGCCTCAAGGAAGGCATGACCGTGGAAGCTGTGGACCCGGCCGCCCG
CGCGGCCCAACTCGTGCCGGCCAGCCAGCCGCGCGGGCGCGGACGCCGCCGCGATGGCGGCAGCTGGGGCGGCGCCAGCG
GCGCTCAAGGAGAACGTGGAGAGCGCGGCGCCAGCGCGCCGCAGGGTGAACATCGCCGCCAGCGCGAAGGTGCCGGGTCC
GGCGCCGATGCGAGCGGCGCCGCGGCCGAGGCTCCTGCTCCGCGCCGCCAGCCGTAA

Upstream 100 bases:

>100_bases
GGGCGAGTGCCGCACCTGATGCGGCATACTGCAGCATCGCCGCGCCCACGACGGCGCGAAGAACGCCGGCGCATTGCGCG
CCGCTTCCAGGATTCCGGAA

Downstream 100 bases:

>100_bases
GGAATCCGCATGAACCCGTCACGCCTCTTCATCGAGCGCCCGGTAGCCACGGCGCTGCTGATGCTGGCCATCCTGCTCTC
GGGGCTGGTGGCCTACCGGC

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MPNPEQGQQQPIPPSRPPEVPGPAGSPRRKLIAAALVVLLAGGGWYWYSHRGAGADAQGTQGARGPGGPGGASGPGAGGR
GGPGGPGAPRSPVVVSTVAQRDMDVTLNGLGNVTPVSNVTVRAQVSGPLLKVLFKEGQMVKAGDVLAEIDPRPFQAAFDQ
AVGQLARDQALLQNARLDQKRYRTLLQQDSISSQQVDTQDALVRQYEGVVKTDQGNVDNARLQLGYTKVVAPVSGRIGLR
QVDPGNIVNTSDTNGIALITQIQPIAVLYTIPEDSLPAVLKKLNSGEKMPVQAWDRQMRNQLGDGTLLTTDNQIDTTTGT
VKMKAIFPNADGMLFPNQFVNVRTRVDTLKDATVIPVAAVQRGQQGTFVYVVDDSSKVRVQVVTLGPSDGNRTAVLKGVE
PGQRVVVDGADRLKEGMTVEAVDPAARAAQLVPASQPRGRGRRRDGGSWGGASGAQGERGERGASAPQGEHRRQREGAGS
GADASGAAAEAPAPRRQP

Sequences:

>Translated_498_residues
MPNPEQGQQQPIPPSRPPEVPGPAGSPRRKLIAAALVVLLAGGGWYWYSHRGAGADAQGTQGARGPGGPGGASGPGAGGR
GGPGGPGAPRSPVVVSTVAQRDMDVTLNGLGNVTPVSNVTVRAQVSGPLLKVLFKEGQMVKAGDVLAEIDPRPFQAAFDQ
AVGQLARDQALLQNARLDQKRYRTLLQQDSISSQQVDTQDALVRQYEGVVKTDQGNVDNARLQLGYTKVVAPVSGRIGLR
QVDPGNIVNTSDTNGIALITQIQPIAVLYTIPEDSLPAVLKKLNSGEKMPVQAWDRQMRNQLGDGTLLTTDNQIDTTTGT
VKMKAIFPNADGMLFPNQFVNVRTRVDTLKDATVIPVAAVQRGQQGTFVYVVDDSSKVRVQVVTLGPSDGNRTAVLKGVE
PGQRVVVDGADRLKEGMTVEAVDPAARAAQLVPASQPRGRGRRRDGGSWGGASGAQGERGERGASAPQGEHRRQREGAGS
GADASGAAAEAPAPRRQP
>Mature_497_residues
PNPEQGQQQPIPPSRPPEVPGPAGSPRRKLIAAALVVLLAGGGWYWYSHRGAGADAQGTQGARGPGGPGGASGPGAGGRG
GPGGPGAPRSPVVVSTVAQRDMDVTLNGLGNVTPVSNVTVRAQVSGPLLKVLFKEGQMVKAGDVLAEIDPRPFQAAFDQA
VGQLARDQALLQNARLDQKRYRTLLQQDSISSQQVDTQDALVRQYEGVVKTDQGNVDNARLQLGYTKVVAPVSGRIGLRQ
VDPGNIVNTSDTNGIALITQIQPIAVLYTIPEDSLPAVLKKLNSGEKMPVQAWDRQMRNQLGDGTLLTTDNQIDTTTGTV
KMKAIFPNADGMLFPNQFVNVRTRVDTLKDATVIPVAAVQRGQQGTFVYVVDDSSKVRVQVVTLGPSDGNRTAVLKGVEP
GQRVVVDGADRLKEGMTVEAVDPAARAAQLVPASQPRGRGRRRDGGSWGGASGAQGERGERGASAPQGEHRRQREGAGSG
ADASGAAAEAPAPRRQP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=381, Percent_Identity=45.6692913385827, Blast_Score=330, Evalue=1e-91,
Organism=Escherichia coli, GI1786668, Length=350, Percent_Identity=34, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1789665, Length=342, Percent_Identity=32.7485380116959, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1789929, Length=326, Percent_Identity=28.2208588957055, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081951, Length=119, Percent_Identity=37.8151260504202, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 52124; Mature: 51993

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNPEQGQQQPIPPSRPPEVPGPAGSPRRKLIAAALVVLLAGGGWYWYSHRGAGADAQGT
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
QGARGPGGPGGASGPGAGGRGGPGGPGAPRSPVVVSTVAQRDMDVTLNGLGNVTPVSNVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCEEEECCCCCCCCCCCEE
VRAQVSGPLLKVLFKEGQMVKAGDVLAEIDPRPFQAAFDQAVGQLARDQALLQNARLDQK
EEEECCCHHHHHHHHCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
RYRTLLQQDSISSQQVDTQDALVRQYEGVVKTDQGNVDNARLQLGYTKVVAPVSGRIGLR
HHHHHHHHCCCCHHHCCHHHHHHHHHCCCEECCCCCCCCEEEEECEEEEEECCCCCCCEE
QVDPGNIVNTSDTNGIALITQIQPIAVLYTIPEDSLPAVLKKLNSGEKMPVQAWDRQMRN
ECCCCCEECCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
QLGDGTLLTTDNQIDTTTGTVKMKAIFPNADGMLFPNQFVNVRTRVDTLKDATVIPVAAV
HCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHH
QRGQQGTFVYVVDDSSKVRVQVVTLGPSDGNRTAVLKGVEPGQRVVVDGADRLKEGMTVE
CCCCCCCEEEEEECCCCEEEEEEEECCCCCCCEEEEECCCCCCEEEECCHHHHHCCCEEE
AVDPAARAAQLVPASQPRGRGRRRDGGSWGGASGAQGERGERGASAPQGEHRRQREGAGS
ECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
GADASGAAAEAPAPRRQP
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PNPEQGQQQPIPPSRPPEVPGPAGSPRRKLIAAALVVLLAGGGWYWYSHRGAGADAQGT
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
QGARGPGGPGGASGPGAGGRGGPGGPGAPRSPVVVSTVAQRDMDVTLNGLGNVTPVSNVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCEEEECCCCCCCCCCCEE
VRAQVSGPLLKVLFKEGQMVKAGDVLAEIDPRPFQAAFDQAVGQLARDQALLQNARLDQK
EEEECCCHHHHHHHHCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
RYRTLLQQDSISSQQVDTQDALVRQYEGVVKTDQGNVDNARLQLGYTKVVAPVSGRIGLR
HHHHHHHHCCCCHHHCCHHHHHHHHHCCCEECCCCCCCCEEEEECEEEEEECCCCCCCEE
QVDPGNIVNTSDTNGIALITQIQPIAVLYTIPEDSLPAVLKKLNSGEKMPVQAWDRQMRN
ECCCCCEECCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
QLGDGTLLTTDNQIDTTTGTVKMKAIFPNADGMLFPNQFVNVRTRVDTLKDATVIPVAAV
HCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHH
QRGQQGTFVYVVDDSSKVRVQVVTLGPSDGNRTAVLKGVEPGQRVVVDGADRLKEGMTVE
CCCCCCCEEEEEECCCCEEEEEEEECCCCCCCEEEEECCCCCCEEEECCHHHHHCCCEEE
AVDPAARAAQLVPASQPRGRGRRRDGGSWGGASGAQGERGERGASAPQGEHRRQREGAGS
ECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
GADASGAAAEAPAPRRQP
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA