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The map label for this gene is moaC

Identifier: 73540246

GI number: 73540246

Start: 586458

End: 586943

Strand: Reverse

Name: moaC

Synonym: Reut_A0540

Alternate gene names: 73540246

Gene position: 586943-586458 (Counterclockwise)

Preceding gene: 73540248

Following gene: 73540244

Centisome position: 15.42

GC content: 65.84

Gene sequence:

>486_bases
ATGACGCAGCTCACCCATTTCGATACCGCCGGACAGGCCCATATGGTCGACGTCGGCGACAAGGCCAGCACGCACCGCGT
GGCCGTGGCAACCGGCACCATCACGATGCTGCCCGACACGTTTGCGCTGGTGCGCGACGGCAACGCAAAGAAAGGCGACG
TGCTGGGCATCGCGCGGGTCGCGGCGATCATGGCAACCAAGCGCACCGCCGACCTGATCCCGCTATGCCACCCGATCGGG
CTGACCAAGGTCGCGGTGGACTTCGCGCTGGACGAGGCTGGCTCCAGCATTACCTGCACCGTCCGCACCGAAACGCGGGG
TCAGACCGGCGTGGAGATGGAGGCGCTGACGGGCGTGCAGGTCGCGCTGCTCACCATCTATGACATGTGCAAGGCGGTGG
ACCGCGGCATGGTGATGGGCAATGTGAAGCTGCTGGAGAAGCACGGCGGGAAGTCGGGGGATTGGGTTTCCACACCGGCC
GGCTAA

Upstream 100 bases:

>100_bases
GCCTGCGAAGCAATGGGGTCTTGGGCATGTTGCTATGATAGCGGCCTCCGCAACCCGTTCCCATCGGCGGTTGCACGCCC
TTGCCGTACAGGATCCAGCC

Downstream 100 bases:

>100_bases
TGGTTCCATAAGCCTGTGTCTGCCCGGGCCGGCGGCCACGGCGTCATCCCGGCGCATCAGAGGCAGCCAGCACAAGAACA
TCGACGTCCTGTTCCCGCGA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTQLTHFDTAGQAHMVDVGDKASTHRVAVATGTITMLPDTFALVRDGNAKKGDVLGIARVAAIMATKRTADLIPLCHPIG
LTKVAVDFALDEAGSSITCTVRTETRGQTGVEMEALTGVQVALLTIYDMCKAVDRGMVMGNVKLLEKHGGKSGDWVSTPA
G

Sequences:

>Translated_161_residues
MTQLTHFDTAGQAHMVDVGDKASTHRVAVATGTITMLPDTFALVRDGNAKKGDVLGIARVAAIMATKRTADLIPLCHPIG
LTKVAVDFALDEAGSSITCTVRTETRGQTGVEMEALTGVQVALLTIYDMCKAVDRGMVMGNVKLLEKHGGKSGDWVSTPA
G
>Mature_160_residues
TQLTHFDTAGQAHMVDVGDKASTHRVAVATGTITMLPDTFALVRDGNAKKGDVLGIARVAAIMATKRTADLIPLCHPIGL
TKVAVDFALDEAGSSITCTVRTETRGQTGVEMEALTGVQVALLTIYDMCKAVDRGMVMGNVKLLEKHGGKSGDWVSTPAG

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=54.1935483870968, Blast_Score=164, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=46.3087248322148, Blast_Score=139, Evalue=8e-34,
Organism=Drosophila melanogaster, GI28574490, Length=160, Percent_Identity=48.75, Blast_Score=142, Evalue=7e-35,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=51.0948905109489, Blast_Score=130, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_CUPPJ (Q475L1)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_294766.1
- ProteinModelPortal:   Q475L1
- SMR:   Q475L1
- GeneID:   3611088
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A0540
- NMPDR:   fig|264198.3.peg.1052
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK09364
- BioCyc:   REUT264198:REUT_A0540-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 16882; Mature: 16751

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLTHFDTAGQAHMVDVGDKASTHRVAVATGTITMLPDTFALVRDGNAKKGDVLGIARV
CCCCCCCCCCCCEEEEECCCCCCCCEEEEEECEEEECCCCEEEEECCCCCCCCHHHHHHH
AAIMATKRTADLIPLCHPIGLTKVAVDFALDEAGSSITCTVRTETRGQTGVEMEALTGVQ
HHHHHHCCCCCCCCCCCCCCCHHHHEEEHHHCCCCEEEEEEEECCCCCCCCEEEHHCCHH
VALLTIYDMCKAVDRGMVMGNVKLLEKHGGKSGDWVSTPAG
HHHHHHHHHHHHHHCCEEECCEEEEECCCCCCCCEECCCCC
>Mature Secondary Structure 
TQLTHFDTAGQAHMVDVGDKASTHRVAVATGTITMLPDTFALVRDGNAKKGDVLGIARV
CCCCCCCCCCCEEEEECCCCCCCCEEEEEECEEEECCCCEEEEECCCCCCCCHHHHHHH
AAIMATKRTADLIPLCHPIGLTKVAVDFALDEAGSSITCTVRTETRGQTGVEMEALTGVQ
HHHHHHCCCCCCCCCCCCCCCHHHHEEEHHHCCCCEEEEEEEECCCCCCCCEEEHHCCHH
VALLTIYDMCKAVDRGMVMGNVKLLEKHGGKSGDWVSTPAG
HHHHHHHHHHHHHHCCEEECCEEEEECCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA