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The map label for this gene is tctD [H]

Identifier: 73540232

GI number: 73540232

Start: 572611

End: 573300

Strand: Reverse

Name: tctD [H]

Synonym: Reut_A0526

Alternate gene names: 73540232

Gene position: 573300-572611 (Counterclockwise)

Preceding gene: 73540241

Following gene: 73540231

Centisome position: 15.06

GC content: 64.78

Gene sequence:

>690_bases
ATGCGCATTCTGATTGCCGAAGATGACGATGTGCTTGCCGACGGCCTGACGCGCTCGCTGCGTCACTCCGGCTATGCGGT
CGACCATGTCGCGAATGGCCTCGAGGCCGATTCCGCGCTGTCGACCCAGACTTTCGACCTGCTGATCCTGGATCTTGGCC
TGCCGCGCATGCCGGGTCTGGAAGTGCTCAAGCGCCTGCGCGCGCGCGGCGCCATGCTGCCGGTGCTGATCCTGACCGCT
GCCGACGGCGTCGATGAGCGCGTCAAGGGACTGGACCTCGGTGCTGACGACTATATGGCAAAACCGTTTGCGTTGTCCGA
ACTCGAAGCCCGGGTGCGCGCGCTGGTGCGCCGCGGCGCCGGCGGCGGCGCGACGCTGATGCGCCACGGGCCGCTCGCAT
TCGACCAGGTCGGTCGCATTGCCTATATGAACGAGCAGATGCTGGACTTGTCGGCACGCGAGGTCGGGCTGCTCGAGATC
CTCCTCACTCGCTGCGGGCGGCTGGTCTCCAAGGAACAGCTCGTGGACCATCTGTGCGAGTGGGGCGAAGAGGTCAGTAA
CAACGCGATCGAGGTCTACGTGCACCGGCTGCGCAAAAAGATCGAAGTTGGTGGCATCCGCATTGCCACGGTACGCGGGC
TTGGCTACTGCCTGGAGAAGTTCCAGCCAAGCGTGGCCGCGCATAGCTGA

Upstream 100 bases:

>100_bases
CGGAATGTGCGGGTACTGTATAAAAAAACAGTATGCTTGGCAAGCCCTGTCCGCATCGTTTGCGTGGCGACTGGCAATGC
CGGCCGTGGTGGAGACAACC

Downstream 100 bases:

>100_bases
CGCGCATCCGCAGCGCTTCCCGCCACGTTACCGAGCAGCCGATCACTCGACCGAATCCGCCCACACTTTGCCGAGATGAG
CTTGCTGCGACTGCCATGGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MRILIAEDDDVLADGLTRSLRHSGYAVDHVANGLEADSALSTQTFDLLILDLGLPRMPGLEVLKRLRARGAMLPVLILTA
ADGVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGAGGGATLMRHGPLAFDQVGRIAYMNEQMLDLSAREVGLLEI
LLTRCGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEVGGIRIATVRGLGYCLEKFQPSVAAHS

Sequences:

>Translated_229_residues
MRILIAEDDDVLADGLTRSLRHSGYAVDHVANGLEADSALSTQTFDLLILDLGLPRMPGLEVLKRLRARGAMLPVLILTA
ADGVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGAGGGATLMRHGPLAFDQVGRIAYMNEQMLDLSAREVGLLEI
LLTRCGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEVGGIRIATVRGLGYCLEKFQPSVAAHS
>Mature_229_residues
MRILIAEDDDVLADGLTRSLRHSGYAVDHVANGLEADSALSTQTFDLLILDLGLPRMPGLEVLKRLRARGAMLPVLILTA
ADGVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGAGGGATLMRHGPLAFDQVGRIAYMNEQMLDLSAREVGLLEI
LLTRCGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEVGGIRIATVRGLGYCLEKFQPSVAAHS

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=45.4128440366972, Blast_Score=183, Evalue=7e-48,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=44.0366972477064, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=36.6515837104072, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=38.7387387387387, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=35.4545454545455, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=34.841628959276, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=33.6244541484716, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=33.6322869955157, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=32.7354260089686, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=31.6742081447964, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=30.3030303030303, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=28.3261802575107, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=105, Percent_Identity=37.1428571428571, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=37.3913043478261, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=36.6336633663366, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=36.1111111111111, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=172, Percent_Identity=28.4883720930233, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=24.6753246753247, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=29.7520661157025, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25052; Mature: 25052

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIAEDDDVLADGLTRSLRHSGYAVDHVANGLEADSALSTQTFDLLILDLGLPRMPGL
CEEEEECCCCHHHHHHHHHHHHCCEEHHHHHCCCCCCHHCCHHHHHHEEEECCCCCCCCH
EVLKRLRARGAMLPVLILTAADGVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGA
HHHHHHHHCCCHHHHHEEECCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCC
GGGATLMRHGPLAFDQVGRIAYMNEQMLDLSAREVGLLEILLTRCGRLVSKEQLVDHLCE
CCCCHHHHCCCCCHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGEEVSNNAIEVYVHRLRKKIEVGGIRIATVRGLGYCLEKFQPSVAAHS
HHHHHCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRILIAEDDDVLADGLTRSLRHSGYAVDHVANGLEADSALSTQTFDLLILDLGLPRMPGL
CEEEEECCCCHHHHHHHHHHHHCCEEHHHHHCCCCCCHHCCHHHHHHEEEECCCCCCCCH
EVLKRLRARGAMLPVLILTAADGVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGA
HHHHHHHHCCCHHHHHEEECCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCC
GGGATLMRHGPLAFDQVGRIAYMNEQMLDLSAREVGLLEILLTRCGRLVSKEQLVDHLCE
CCCCHHHHCCCCCHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGEEVSNNAIEVYVHRLRKKIEVGGIRIATVRGLGYCLEKFQPSVAAHS
HHHHHCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]