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The map label for this gene is qseC [H]

Identifier: 73540231

GI number: 73540231

Start: 570982

End: 572535

Strand: Reverse

Name: qseC [H]

Synonym: Reut_A0525

Alternate gene names: 73540231

Gene position: 572535-570982 (Counterclockwise)

Preceding gene: 73540232

Following gene: 73540230

Centisome position: 15.04

GC content: 67.89

Gene sequence:

>1554_bases
ATGAGCTTGCTGCGACTGCCATGGCGACATCCGCCCGCAAAGGATCCCGTCCCTCCCCCCGGTGCCGCCACGCCGGACGA
CCCGGACGACCTGGCCGATGCTCTGCCCCACCTGGAGGAGAGCACCGGCCAACCTGCCCCGCGCTCGCTGTTCGGCGAGA
TCCTGGACTGGATGCTGGCGCCGCTGCTGCTGCTCTGGCCGATGAGCATCGCCGTCACGTATCTGGTGGCGAAATCCATC
GCCAACGGGCCGTTCGACCGCGCGCTGGAAGCCAGCGCCATCGTGCTATCGCAGCAGGTCCGCGAAGTGAACGGCCGCGT
CACGCTGCAGCTGCCGCTGTCGGCGCGCGAGATCCTGCGCGCGGACGAAACCGACAACATTTACTACCAGATCGTCGGCA
AGCGCGGTGAGTATGTGGCCGGCGACCACGACCTGCCACTGCCGTCCGAGGAGGACGAGGGCCATCCCGGCCTGGTATCG
CTGCGCGATGACCGCGTGTCGGGCAACGACGTGCGCGTGGCCTATACCTATATCGATCTCAAGAACGTAGGCGGCAACCA
GCCCGTGCTGGTGCAGGTGGCCGAGACCCTCGACAAGCGCGCGCGCCTGGCCAACGAAATCATCAAGGGCGTGATCCTGC
CGCAGTTCGTGATCCTGCCGCTGGCTGTGGTGCTCGTGTGGTTCGGGCTCTCGCGCGGACTGGCGCCGCTCACGGCGATC
CAGCAACGCATCCGCGCGCGCAATCCCGGCGACACCAGCCCCATCGACGAACGCGCGGCGCCGCAGGAAATCACGCCGCT
GGTCGCATCGTTCAACGAACTGCTCGCGCGGCTGGACCAGTCGGTGCAGACGCAGAAGCGCTTCATTGCCGATGCCGCGC
ACCAGATGAAAACGCCGCTGGCCGGACTGCGCATGCAGGCGGAACTGGCCCAGCGCGAACAGTCGCCCGAGGAATTGCGC
CGCTCGCTCGCGCAGATCGCCGGCAGTTCGGAACGCACGGCGCACCTGGTCACGCAATTGCTGTCGCTTGCGCGCATGGA
AAACCTGGCCGGCGCCGGCAGCATGGCGGCGCTGGACCTGGCCGCGCTCGCGCGCGAGGTCGTGAAGGACTGGCTGCCGC
GCGCCTGGGCCCGTCAGATCGACCTGGGACTCGATGCCGACGATCACCCGGTCATGGTGCAGGGCAACCGGCTGATGCTC
ACGGAAATGCTGAACAACCTGATCGATAACGCCATCCGCTATACGCCGATCGGCGGCCACGCCACCGTGCGCGTCACCTC
CGATGCCTTCGAGCCGTTCGCATATCTCGACGTGGAAGACACCGGCCCCGGGATTGCGGCGGCGGACCGCGAGCGCGTGA
TGGAACGTTTCTACCGCGTGCTCGGCACCAACACCGAAGGCAGCGGCCTGGGCCTGGCGATCGTGCGCGAGATCGTGCAG
CAGCACGGCGGTGAAGTCCGCATCGAGGACCACGTCTACCAGCAGGAGCCCCGGCTGGCCGGCGCGCGATTCCGCGTCAC
GCTGCGCCGTCCCGCACCGGAGGCATCAGCGTGA

Upstream 100 bases:

>100_bases
GCCAAGCGTGGCCGCGCATAGCTGACGCGCATCCGCAGCGCTTCCCGCCACGTTACCGAGCAGCCGATCACTCGACCGAA
TCCGCCCACACTTTGCCGAG

Downstream 100 bases:

>100_bases
GCGCGCATCCGCCCGTCGATCCGGCACTCAAACGCTCGTGGCAGCGCAACCGGCGCTGGATCTGCGCGCTGCTCGCGGTC
TGGTTCGTCGTGACCTTTGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MSLLRLPWRHPPAKDPVPPPGAATPDDPDDLADALPHLEESTGQPAPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKSI
ANGPFDRALEASAIVLSQQVREVNGRVTLQLPLSAREILRADETDNIYYQIVGKRGEYVAGDHDLPLPSEEDEGHPGLVS
LRDDRVSGNDVRVAYTYIDLKNVGGNQPVLVQVAETLDKRARLANEIIKGVILPQFVILPLAVVLVWFGLSRGLAPLTAI
QQRIRARNPGDTSPIDERAAPQEITPLVASFNELLARLDQSVQTQKRFIADAAHQMKTPLAGLRMQAELAQREQSPEELR
RSLAQIAGSSERTAHLVTQLLSLARMENLAGAGSMAALDLAALAREVVKDWLPRAWARQIDLGLDADDHPVMVQGNRLML
TEMLNNLIDNAIRYTPIGGHATVRVTSDAFEPFAYLDVEDTGPGIAAADRERVMERFYRVLGTNTEGSGLGLAIVREIVQ
QHGGEVRIEDHVYQQEPRLAGARFRVTLRRPAPEASA

Sequences:

>Translated_517_residues
MSLLRLPWRHPPAKDPVPPPGAATPDDPDDLADALPHLEESTGQPAPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKSI
ANGPFDRALEASAIVLSQQVREVNGRVTLQLPLSAREILRADETDNIYYQIVGKRGEYVAGDHDLPLPSEEDEGHPGLVS
LRDDRVSGNDVRVAYTYIDLKNVGGNQPVLVQVAETLDKRARLANEIIKGVILPQFVILPLAVVLVWFGLSRGLAPLTAI
QQRIRARNPGDTSPIDERAAPQEITPLVASFNELLARLDQSVQTQKRFIADAAHQMKTPLAGLRMQAELAQREQSPEELR
RSLAQIAGSSERTAHLVTQLLSLARMENLAGAGSMAALDLAALAREVVKDWLPRAWARQIDLGLDADDHPVMVQGNRLML
TEMLNNLIDNAIRYTPIGGHATVRVTSDAFEPFAYLDVEDTGPGIAAADRERVMERFYRVLGTNTEGSGLGLAIVREIVQ
QHGGEVRIEDHVYQQEPRLAGARFRVTLRRPAPEASA
>Mature_516_residues
SLLRLPWRHPPAKDPVPPPGAATPDDPDDLADALPHLEESTGQPAPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKSIA
NGPFDRALEASAIVLSQQVREVNGRVTLQLPLSAREILRADETDNIYYQIVGKRGEYVAGDHDLPLPSEEDEGHPGLVSL
RDDRVSGNDVRVAYTYIDLKNVGGNQPVLVQVAETLDKRARLANEIIKGVILPQFVILPLAVVLVWFGLSRGLAPLTAIQ
QRIRARNPGDTSPIDERAAPQEITPLVASFNELLARLDQSVQTQKRFIADAAHQMKTPLAGLRMQAELAQREQSPEELRR
SLAQIAGSSERTAHLVTQLLSLARMENLAGAGSMAALDLAALAREVVKDWLPRAWARQIDLGLDADDHPVMVQGNRLMLT
EMLNNLIDNAIRYTPIGGHATVRVTSDAFEPFAYLDVEDTGPGIAAADRERVMERFYRVLGTNTEGSGLGLAIVREIVQQ
HGGEVRIEDHVYQQEPRLAGARFRVTLRRPAPEASA

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=350, Percent_Identity=32.5714285714286, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1786783, Length=331, Percent_Identity=31.1178247734139, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1790551, Length=306, Percent_Identity=29.4117647058824, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=29.7297297297297, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=29.3617021276596, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1788279, Length=302, Percent_Identity=26.8211920529801, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790861, Length=314, Percent_Identity=28.343949044586, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=30.2521008403361, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=26.0330578512397, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787894, Length=314, Percent_Identity=28.9808917197452, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790436, Length=200, Percent_Identity=31.5, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787374, Length=297, Percent_Identity=27.6094276094276, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=26.2237762237762, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=290, Percent_Identity=26.551724137931, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI48994928, Length=244, Percent_Identity=23.7704918032787, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=30.2904564315353, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=219, Percent_Identity=25.1141552511416, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56773; Mature: 56641

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLRLPWRHPPAKDPVPPPGAATPDDPDDLADALPHLEESTGQPAPRSLFGEILDWMLA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
PLLLLWPMSIAVTYLVAKSIANGPFDRALEASAIVLSQQVREVNGRVTLQLPLSAREILR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHC
ADETDNIYYQIVGKRGEYVAGDHDLPLPSEEDEGHPGLVSLRDDRVSGNDVRVAYTYIDL
CCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEEE
KNVGGNQPVLVQVAETLDKRARLANEIIKGVILPQFVILPLAVVLVWFGLSRGLAPLTAI
ECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QQRIRARNPGDTSPIDERAAPQEITPLVASFNELLARLDQSVQTQKRFIADAAHQMKTPL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AGLRMQAELAQREQSPEELRRSLAQIAGSSERTAHLVTQLLSLARMENLAGAGSMAALDL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AALAREVVKDWLPRAWARQIDLGLDADDHPVMVQGNRLMLTEMLNNLIDNAIRYTPIGGH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEHHHHHHHHHHHHEEECCCCCC
ATVRVTSDAFEPFAYLDVEDTGPGIAAADRERVMERFYRVLGTNTEGSGLGLAIVREIVQ
EEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
QHGGEVRIEDHVYQQEPRLAGARFRVTLRRPAPEASA
HCCCEEEEHHHHHHCCCCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure 
SLLRLPWRHPPAKDPVPPPGAATPDDPDDLADALPHLEESTGQPAPRSLFGEILDWMLA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
PLLLLWPMSIAVTYLVAKSIANGPFDRALEASAIVLSQQVREVNGRVTLQLPLSAREILR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHC
ADETDNIYYQIVGKRGEYVAGDHDLPLPSEEDEGHPGLVSLRDDRVSGNDVRVAYTYIDL
CCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEEE
KNVGGNQPVLVQVAETLDKRARLANEIIKGVILPQFVILPLAVVLVWFGLSRGLAPLTAI
ECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QQRIRARNPGDTSPIDERAAPQEITPLVASFNELLARLDQSVQTQKRFIADAAHQMKTPL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AGLRMQAELAQREQSPEELRRSLAQIAGSSERTAHLVTQLLSLARMENLAGAGSMAALDL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AALAREVVKDWLPRAWARQIDLGLDADDHPVMVQGNRLMLTEMLNNLIDNAIRYTPIGGH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEHHHHHHHHHHHHEEECCCCCC
ATVRVTSDAFEPFAYLDVEDTGPGIAAADRERVMERFYRVLGTNTEGSGLGLAIVREIVQ
EEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
QHGGEVRIEDHVYQQEPRLAGARFRVTLRRPAPEASA
HCCCEEEEHHHHHHCCCCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]