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The map label for this gene is yhdG [H]

Identifier: 73539956

GI number: 73539956

Start: 277614

End: 279011

Strand: Direct

Name: yhdG [H]

Synonym: Reut_A0250

Alternate gene names: 73539956

Gene position: 277614-279011 (Clockwise)

Preceding gene: 73539955

Following gene: 73539958

Centisome position: 7.29

GC content: 63.52

Gene sequence:

>1398_bases
ATGAGTCTGTTCCGCACCAAGAATATCGACGCCATGCTCGCCGTGGCACACAACGACGGCCTGAAGAAGGTCCTCGGGCC
GATGGATCTCGTGATGATGGGCATCGGCGCCATCATCGGCACCGGCATTTTCGTGCTGACCGGGACCGGTGCCCTGACCG
CGGGGCCCGCACTTACCGTGTCATTCGTGATTGCCGCGATGGCCTGCGGTTTTGCCGCGCTGTGCTACGCGGAGTTCGCG
TCGGCCATTCCCGTCTCGGGTTCTATCTACACCTATAGCTATGCCACGCTCGGCGAGATCATCGCCTGGATGATCGGCTG
GGACCTGTTGCTCGAATACGGCCTCGCCACGTCAGCGGTGTCGGTGGGCTGGTCCGGCTATTTCCAGTCGCTGGTGTCCG
GATTCGGCGTGAAGTTGCCGGCCGCGCTGACCGCGGCGCCCGGTGCGGTGCCCGGTGTCGAGACCATGGTGAACTTGCCG
GCCGTGCTGATCATGCTGGCGATTACGTGGATCGTGTCGTACGGCGTGAAGGAATCGGCGCGGTTGAACAACGTGATGGT
GGCGATCAAGATCGGCGTGGTGCTGCTGTTCATCGCGGTCGGCGTATGGCACGTGAAGCCGGCCAACTGGGAGCCGTTCG
CGCCGTTCGGCATGACTGGCGTGTTCAATGCGGCGGCGCTCGTGTTCTTCGCTTTCATCGGCTTCGATGCCGTGACCTCG
GCCGCCGAAGAGGTACGCAATCCGAGCAAGGACTTGCCGATTGGCATCATCGGCTCGTTGGCCGTCTGCACGGTGCTCTA
CGTTGTCGTGGCCGCGATCATGACGGGCATCGTTCCGTTCGCCAAGTTCGCGGGCGTGGATCACCCCGTGTCGCTGGCGC
TGCAGTACGCGGGAAAGAACTGGGTGGCGGGCTTTGTCGATCTTGGTGCCATTCTCGGCATGACCACGGTGATCCTGGTG
ATGACCTACGGCCAGACCCGCATCATCTTCGCGATGTCGCGTGACGGCCTGCTGCCCGAGCGACTGTCATCGGTGCATCC
GGTGCATGCCACGCCATACTTCGCCACGTGGACCGTCGGCATCGTGTTTGCCGCGATTGCCGGCTTCGTGCCGCTCAATG
TGCTGGCGGAGTTGATCAACATCGGCACGCTGGCAGCATTCACACTGATCTCCATCGCCGTGCTGGTGCTGCGCCGCACG
CGCCCCGATCTGCCGCGTGCATTCCGCTGCCCTGGCGTGCCCGTGGTGCCGCTGCTGTCGGCCGGTTTCTGCCTGTTCCT
GATGGCGCATCTGCAGGCACTCACGTGGATCGCATTCCTGGTCTGGCTCGTGATCGGGCTGGCGATCTATTTCCTCTACG
CGCGGCGCAACGCCGTGCTGCATAACCACGGCGGCTGA

Upstream 100 bases:

>100_bases
AAATAGTGACCCGACGCGCACCCCCAAAAGAGTAAACTCCGACCCTTTCCAGAAAAGCCGAATCCCCTCCACAAGACGGG
CATTCGCAGGAGTTGCTCCG

Downstream 100 bases:

>100_bases
GCCCGCCGCTGGCCTAGCGTTTGGAGGCGGCCTCGCGCATGAACGCTACCGCGCGAGGCTCGTTGACATAGGCGGTGTTG
ACGCGGATCCATGCCGAGGT

Product: amino acid permease-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSLFRTKNIDAMLAVAHNDGLKKVLGPMDLVMMGIGAIIGTGIFVLTGTGALTAGPALTVSFVIAAMACGFAALCYAEFA
SAIPVSGSIYTYSYATLGEIIAWMIGWDLLLEYGLATSAVSVGWSGYFQSLVSGFGVKLPAALTAAPGAVPGVETMVNLP
AVLIMLAITWIVSYGVKESARLNNVMVAIKIGVVLLFIAVGVWHVKPANWEPFAPFGMTGVFNAAALVFFAFIGFDAVTS
AAEEVRNPSKDLPIGIIGSLAVCTVLYVVVAAIMTGIVPFAKFAGVDHPVSLALQYAGKNWVAGFVDLGAILGMTTVILV
MTYGQTRIIFAMSRDGLLPERLSSVHPVHATPYFATWTVGIVFAAIAGFVPLNVLAELINIGTLAAFTLISIAVLVLRRT
RPDLPRAFRCPGVPVVPLLSAGFCLFLMAHLQALTWIAFLVWLVIGLAIYFLYARRNAVLHNHGG

Sequences:

>Translated_465_residues
MSLFRTKNIDAMLAVAHNDGLKKVLGPMDLVMMGIGAIIGTGIFVLTGTGALTAGPALTVSFVIAAMACGFAALCYAEFA
SAIPVSGSIYTYSYATLGEIIAWMIGWDLLLEYGLATSAVSVGWSGYFQSLVSGFGVKLPAALTAAPGAVPGVETMVNLP
AVLIMLAITWIVSYGVKESARLNNVMVAIKIGVVLLFIAVGVWHVKPANWEPFAPFGMTGVFNAAALVFFAFIGFDAVTS
AAEEVRNPSKDLPIGIIGSLAVCTVLYVVVAAIMTGIVPFAKFAGVDHPVSLALQYAGKNWVAGFVDLGAILGMTTVILV
MTYGQTRIIFAMSRDGLLPERLSSVHPVHATPYFATWTVGIVFAAIAGFVPLNVLAELINIGTLAAFTLISIAVLVLRRT
RPDLPRAFRCPGVPVVPLLSAGFCLFLMAHLQALTWIAFLVWLVIGLAIYFLYARRNAVLHNHGG
>Mature_464_residues
SLFRTKNIDAMLAVAHNDGLKKVLGPMDLVMMGIGAIIGTGIFVLTGTGALTAGPALTVSFVIAAMACGFAALCYAEFAS
AIPVSGSIYTYSYATLGEIIAWMIGWDLLLEYGLATSAVSVGWSGYFQSLVSGFGVKLPAALTAAPGAVPGVETMVNLPA
VLIMLAITWIVSYGVKESARLNNVMVAIKIGVVLLFIAVGVWHVKPANWEPFAPFGMTGVFNAAALVFFAFIGFDAVTSA
AEEVRNPSKDLPIGIIGSLAVCTVLYVVVAAIMTGIVPFAKFAGVDHPVSLALQYAGKNWVAGFVDLGAILGMTTVILVM
TYGQTRIIFAMSRDGLLPERLSSVHPVHATPYFATWTVGIVFAAIAGFVPLNVLAELINIGTLAAFTLISIAVLVLRRTR
PDLPRAFRCPGVPVVPLLSAGFCLFLMAHLQALTWIAFLVWLVIGLAIYFLYARRNAVLHNHGG

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614003, Length=493, Percent_Identity=33.6713995943205, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI258614005, Length=493, Percent_Identity=33.6713995943205, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI258645169, Length=493, Percent_Identity=34.0770791075051, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI181337167, Length=408, Percent_Identity=36.2745098039216, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI4507047, Length=438, Percent_Identity=34.0182648401827, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI110347453, Length=389, Percent_Identity=34.9614395886889, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI114326544, Length=434, Percent_Identity=32.7188940092166, Blast_Score=205, Evalue=8e-53,
Organism=Homo sapiens, GI114326550, Length=434, Percent_Identity=32.7188940092166, Blast_Score=205, Evalue=8e-53,
Organism=Homo sapiens, GI186910308, Length=408, Percent_Identity=25.2450980392157, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI186910306, Length=408, Percent_Identity=25.2450980392157, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI186910304, Length=408, Percent_Identity=25.2450980392157, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI115648063, Length=408, Percent_Identity=24.0196078431373, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI115648022, Length=408, Percent_Identity=24.0196078431373, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7657683, Length=416, Percent_Identity=26.2019230769231, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI187423910, Length=470, Percent_Identity=25.531914893617, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI7657591, Length=470, Percent_Identity=25.531914893617, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI9790235, Length=296, Percent_Identity=26.6891891891892, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI33286428, Length=455, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI71979932, Length=450, Percent_Identity=27.1111111111111, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87081869, Length=476, Percent_Identity=25.8403361344538, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI87082023, Length=453, Percent_Identity=25.8278145695364, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786302, Length=472, Percent_Identity=22.2457627118644, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082250, Length=470, Percent_Identity=25.531914893617, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081915, Length=423, Percent_Identity=23.8770685579196, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786694, Length=442, Percent_Identity=25.7918552036199, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788480, Length=450, Percent_Identity=24.4444444444444, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789017, Length=454, Percent_Identity=24.0088105726872, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17532491, Length=412, Percent_Identity=34.2233009708738, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17533459, Length=411, Percent_Identity=31.6301703163017, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17531343, Length=392, Percent_Identity=31.8877551020408, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17568033, Length=416, Percent_Identity=25.7211538461538, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17537453, Length=373, Percent_Identity=23.0563002680965, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17540018, Length=415, Percent_Identity=24.578313253012, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319991, Length=347, Percent_Identity=27.0893371757925, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221512776, Length=417, Percent_Identity=35.4916067146283, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24666159, Length=417, Percent_Identity=35.4916067146283, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24668806, Length=434, Percent_Identity=34.5622119815668, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI21356285, Length=434, Percent_Identity=34.5622119815668, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24668802, Length=434, Percent_Identity=34.5622119815668, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24667468, Length=423, Percent_Identity=34.7517730496454, Blast_Score=238, Evalue=8e-63,
Organism=Drosophila melanogaster, GI161077963, Length=430, Percent_Identity=34.6511627906977, Blast_Score=202, Evalue=4e-52,
Organism=Drosophila melanogaster, GI281366235, Length=412, Percent_Identity=32.0388349514563, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI116007820, Length=412, Percent_Identity=32.0388349514563, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI116007818, Length=412, Percent_Identity=32.0388349514563, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI85725152, Length=412, Percent_Identity=32.0388349514563, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21357367, Length=406, Percent_Identity=27.3399014778325, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24651635, Length=409, Percent_Identity=26.161369193154, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24651633, Length=409, Percent_Identity=26.161369193154, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI221331183, Length=430, Percent_Identity=25.8139534883721, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17647653, Length=430, Percent_Identity=25.8139534883721, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24664379, Length=430, Percent_Identity=25.8139534883721, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI45550968, Length=424, Percent_Identity=25.9433962264151, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19921172, Length=424, Percent_Identity=25.9433962264151, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641993, Length=418, Percent_Identity=26.555023923445, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641995, Length=418, Percent_Identity=26.555023923445, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49132; Mature: 49001

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SLFRTKNIDAMLAVAHNDGLKKVLGPMDLVMMGIGAIIGTGIFVLTGTGALTAGPALTV
CCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]