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The map label for this gene is yfgC [C]

Identifier: 73539898

GI number: 73539898

Start: 216866

End: 217825

Strand: Direct

Name: yfgC [C]

Synonym: Reut_A0192

Alternate gene names: 73539898

Gene position: 216866-217825 (Clockwise)

Preceding gene: 73539896

Following gene: 73539901

Centisome position: 5.7

GC content: 65.83

Gene sequence:

>960_bases
ATGTCCCGCCACCTGCCAGGTGTTCCGCGTCCTGTCCTGTCCCGCATGGCCTGTGCGTTGTCCATGGGCGCGGCGATGAG
CATGGCGCCGTTGGCACTGGCCCAGGAGGACCCCGGACAGGAGGATGGCATCCGCTTGCAGCGTGGCGGATCGGCGGTGA
AAAACATCGTACCGGTCGAGGTGATCGAGCAGCAGGCCGCGCAGGAGTACGAGCAGATCAAGCAAGAAGCGATCGCCAAG
CATGCGCTCGCTGGCGACAGCAATGCGCAGCTGCAGCGCCTGCGTGCTATCGGCAAGCGGCTGCTGCCGGAGACCACGCG
CTGGAACGAACGCGCGCGCCAGTGGCAGTGGGAAATCAACCTGATTGGCTCGAAGCAGGTCAATGCGTTCTGCATGCCGG
GCGGCAAGATCGCGTTCTACACGGGCCTGCTCGAACAGCTCAAGCTGACCGACGATGAGATCGCCATGGCCATGGGCCAC
GAGATCGCACACGCGCTGCAGGAGCATGCGCGCGAGCGCGCGGCCAAGTCGGAGATTACCAACCTTGGCGCCAATGTCGT
GTCGCAGCTGTTCGGCTTCGGCAACCTCGGCAATATGGCGCTGGGCACGGGCGCGCATCTGCTGACGCTGCGCTTTTCGC
GTGCGGATGAAAGCGAGGCCGACCTGATCGGCATGGACATTGCCGCGCGCGCCGGCTACGACCCGCGCGCTGCCGTGACG
CTGTGGCAGAAGATGGCCAAGGTCACGCAGTCGGGCGCGGATTTCCTGTCCACGCACCCGTCGGGGCGTACCCGAATTGC
CGATCTCGAGAAGCACATGCCCGAGGTGCTGCCGCTCTACGCGCGCGCCATCAACACCACGGTGGACCGCCTGCCGCCGT
ATCGCGCCAATATGGCCAACCTTGGCGATGCACCCGTCGATGCCGGCGACGACGACCGGCAGCGGCCGCTCAAACGCTGA

Upstream 100 bases:

>100_bases
CCGCGCGGCTGCGCAGGCGCCGTGTATTATTGCATCACCCGTTTGCCCCCTCTGTCCAAGACTGCTCCCGGCTTTCCCTA
CTGCCCCCAAGGAACCGAAC

Downstream 100 bases:

>100_bases
TGATCCCGCAGAAAGTAAAAAAGCCGGCAATGCCGGCTTTTTTACTTGAGACCTTGAAACGCTCAGGCCTGCAGCCCGGT
CGCCTCGTCGGCGCCGACAT

Product: peptidase M48, Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSRHLPGVPRPVLSRMACALSMGAAMSMAPLALAQEDPGQEDGIRLQRGGSAVKNIVPVEVIEQQAAQEYEQIKQEAIAK
HALAGDSNAQLQRLRAIGKRLLPETTRWNERARQWQWEINLIGSKQVNAFCMPGGKIAFYTGLLEQLKLTDDEIAMAMGH
EIAHALQEHARERAAKSEITNLGANVVSQLFGFGNLGNMALGTGAHLLTLRFSRADESEADLIGMDIAARAGYDPRAAVT
LWQKMAKVTQSGADFLSTHPSGRTRIADLEKHMPEVLPLYARAINTTVDRLPPYRANMANLGDAPVDAGDDDRQRPLKR

Sequences:

>Translated_319_residues
MSRHLPGVPRPVLSRMACALSMGAAMSMAPLALAQEDPGQEDGIRLQRGGSAVKNIVPVEVIEQQAAQEYEQIKQEAIAK
HALAGDSNAQLQRLRAIGKRLLPETTRWNERARQWQWEINLIGSKQVNAFCMPGGKIAFYTGLLEQLKLTDDEIAMAMGH
EIAHALQEHARERAAKSEITNLGANVVSQLFGFGNLGNMALGTGAHLLTLRFSRADESEADLIGMDIAARAGYDPRAAVT
LWQKMAKVTQSGADFLSTHPSGRTRIADLEKHMPEVLPLYARAINTTVDRLPPYRANMANLGDAPVDAGDDDRQRPLKR
>Mature_318_residues
SRHLPGVPRPVLSRMACALSMGAAMSMAPLALAQEDPGQEDGIRLQRGGSAVKNIVPVEVIEQQAAQEYEQIKQEAIAKH
ALAGDSNAQLQRLRAIGKRLLPETTRWNERARQWQWEINLIGSKQVNAFCMPGGKIAFYTGLLEQLKLTDDEIAMAMGHE
IAHALQEHARERAAKSEITNLGANVVSQLFGFGNLGNMALGTGAHLLTLRFSRADESEADLIGMDIAARAGYDPRAAVTL
WQKMAKVTQSGADFLSTHPSGRTRIADLEKHMPEVLPLYARAINTTVDRLPPYRANMANLGDAPVDAGDDDRQRPLKR

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TPR repeat [H]

Homologues:

Organism=Homo sapiens, GI21686999, Length=180, Percent_Identity=31.6666666666667, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1788840, Length=207, Percent_Identity=27.0531400966184, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082185, Length=158, Percent_Identity=30.379746835443, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322940, Length=177, Percent_Identity=31.638418079096, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915
- InterPro:   IPR011716
- InterPro:   IPR011990 [H]

Pfam domain/function: PF01435 Peptidase_M48; PF07720 TPR_3 [H]

EC number: NA

Molecular weight: Translated: 34901; Mature: 34770

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRHLPGVPRPVLSRMACALSMGAAMSMAPLALAQEDPGQEDGIRLQRGGSAVKNIVPVE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCCHHH
VIEQQAAQEYEQIKQEAIAKHALAGDSNAQLQRLRAIGKRLLPETTRWNERARQWQWEIN
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEE
LIGSKQVNAFCMPGGKIAFYTGLLEQLKLTDDEIAMAMGHEIAHALQEHARERAAKSEIT
EECCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLGANVVSQLFGFGNLGNMALGTGAHLLTLRFSRADESEADLIGMDIAARAGYDPRAAVT
HHHHHHHHHHHCCCCCCCCHHCCCCEEEEEEECCCCCCCCCEECHHHHHHCCCCCHHHHH
LWQKMAKVTQSGADFLSTHPSGRTRIADLEKHMPEVLPLYARAINTTVDRLPPYRANMAN
HHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LGDAPVDAGDDDRQRPLKR
CCCCCCCCCCCHHCCCCCC
>Mature Secondary Structure 
SRHLPGVPRPVLSRMACALSMGAAMSMAPLALAQEDPGQEDGIRLQRGGSAVKNIVPVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCCHHH
VIEQQAAQEYEQIKQEAIAKHALAGDSNAQLQRLRAIGKRLLPETTRWNERARQWQWEIN
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEE
LIGSKQVNAFCMPGGKIAFYTGLLEQLKLTDDEIAMAMGHEIAHALQEHARERAAKSEIT
EECCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLGANVVSQLFGFGNLGNMALGTGAHLLTLRFSRADESEADLIGMDIAARAGYDPRAAVT
HHHHHHHHHHHCCCCCCCCHHCCCCEEEEEEECCCCCCCCCEECHHHHHHCCCCCHHHHH
LWQKMAKVTQSGADFLSTHPSGRTRIADLEKHMPEVLPLYARAINTTVDRLPPYRANMAN
HHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LGDAPVDAGDDDRQRPLKR
CCCCCCCCCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]