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The map label for this gene is metX [H]

Identifier: 73539892

GI number: 73539892

Start: 210827

End: 211999

Strand: Direct

Name: metX [H]

Synonym: Reut_A0186

Alternate gene names: 73539892

Gene position: 210827-211999 (Clockwise)

Preceding gene: 73539888

Following gene: 73539893

Centisome position: 5.54

GC content: 64.79

Gene sequence:

>1173_bases
ATGACAGATGTCGCCTTGCCGCCTGCCGCGCTCACGCTGCCGAACGATTCCGTCGGCGTCGTCACGCCGCAGCGTATGCA
TTTCCAGGAGCCGCTGAAGCTGCGCAACGGCTCGTCGATCGCCGGGTACGACCTGATGGTCGAGACCTACGGCACGCTCA
ACGCCGACCGCTCCAATGCCGTGCTGGTCTGCCACGCGCTGAACGCGTCGCACCATGTGGCGGGCGTCTATGCGGACGAT
CCGCGCGACGTGGGCTGGTGGGACAACATGGTCGGTCCCGGCAAGCCGCTCGACACCAACCGCTTCTTCGTCATCGGCGT
GAACAACCTGGGTTCGTGTTTCGGGTCCACGGGCCCGATGAGCACCAACCCTGCCACGGGCGAGCCTTATGGTGCGGCGT
TTCCCGTGGTGACCGTCGAGGACTGGGTCAACGCACAGGCGCGGGTGGCGGATGTGTTCGGCATCACGCAGTTCGCCGCG
GTGATGGGCGGCAGCCTGGGCGGCATGCAGGCGGTGGCCTGGAGCCTGATGTATCCGCAGCGGCTGCGCCACTGCATCGT
GGTCGCATCGACCCCCAAGCTTTCGGCGCAGAACATTGCGTTCAACGAGGTCGCGCGCAGCTCGATCCTGTCGGACCCGG
ATTTTCACGGCGGCAACTACTACGCGCATGGCGTGAAGCCAAAGCGCGGCCTGCGCGTGGCCCGCATGATCGGCCATATC
ACTTACCTGTCGGACGAGGACATGGCCGAGAAATTCGGCCGCGAGCTGAAGACCGAGGACATCCGCTTCTCGTTCGATGT
CGAGTTCCAGGTCGAGAGCTACCTGCGCTACCAGGGCGACAAGTTTGCCGAGTATTTCGACGCGAACACCTACCTGCTGA
TCACGCGCGCGCTCGACTATTTCGACCCGGCACTGGCCTATGGCGGCGACCTCACGCGCGCGATGGCGCAGACGCAGGCG
AGCTTCCTCGTCGCGAGCTTTACCACCGACTGGCGCTTTGCGCCGAACCGCAGCCGCGAACTGGTCAAGGCGCTGCTCGA
CAACAAGCGCCCGGTCTCGTACGCCGAGATTGACGCCCCGCACGGCCACGATGCATTCCTGCTCGACGATCCGCGCTACC
ACAACCTGATGCGCGCTTACTACGACCGCATTGCAGAGGAGATCGGCGCATGA

Upstream 100 bases:

>100_bases
CGCCGGCACGCGGAACACCGCGAATGCCCGACTTGGCTGCGACGCTTCACACGCACTGCCGGTCGGGTTTTTTTATGCCT
GCTTCGCGCGGGCCGATTCC

Downstream 100 bases:

>100_bases
ACGCCCTGGCCAATCCGAATATCCTCGCGCTGCGTCCGGACTTCCGCGCGATCGCTCGCTGGATCGAGCCTAATTCCACC
GTGCTCGACCTCGGCTGCGG

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MTDVALPPAALTLPNDSVGVVTPQRMHFQEPLKLRNGSSIAGYDLMVETYGTLNADRSNAVLVCHALNASHHVAGVYADD
PRDVGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPMSTNPATGEPYGAAFPVVTVEDWVNAQARVADVFGITQFAA
VMGGSLGGMQAVAWSLMYPQRLRHCIVVASTPKLSAQNIAFNEVARSSILSDPDFHGGNYYAHGVKPKRGLRVARMIGHI
TYLSDEDMAEKFGRELKTEDIRFSFDVEFQVESYLRYQGDKFAEYFDANTYLLITRALDYFDPALAYGGDLTRAMAQTQA
SFLVASFTTDWRFAPNRSRELVKALLDNKRPVSYAEIDAPHGHDAFLLDDPRYHNLMRAYYDRIAEEIGA

Sequences:

>Translated_390_residues
MTDVALPPAALTLPNDSVGVVTPQRMHFQEPLKLRNGSSIAGYDLMVETYGTLNADRSNAVLVCHALNASHHVAGVYADD
PRDVGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPMSTNPATGEPYGAAFPVVTVEDWVNAQARVADVFGITQFAA
VMGGSLGGMQAVAWSLMYPQRLRHCIVVASTPKLSAQNIAFNEVARSSILSDPDFHGGNYYAHGVKPKRGLRVARMIGHI
TYLSDEDMAEKFGRELKTEDIRFSFDVEFQVESYLRYQGDKFAEYFDANTYLLITRALDYFDPALAYGGDLTRAMAQTQA
SFLVASFTTDWRFAPNRSRELVKALLDNKRPVSYAEIDAPHGHDAFLLDDPRYHNLMRAYYDRIAEEIGA
>Mature_389_residues
TDVALPPAALTLPNDSVGVVTPQRMHFQEPLKLRNGSSIAGYDLMVETYGTLNADRSNAVLVCHALNASHHVAGVYADDP
RDVGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPMSTNPATGEPYGAAFPVVTVEDWVNAQARVADVFGITQFAAV
MGGSLGGMQAVAWSLMYPQRLRHCIVVASTPKLSAQNIAFNEVARSSILSDPDFHGGNYYAHGVKPKRGLRVARMIGHIT
YLSDEDMAEKFGRELKTEDIRFSFDVEFQVESYLRYQGDKFAEYFDANTYLLITRALDYFDPALAYGGDLTRAMAQTQAS
FLVASFTTDWRFAPNRSRELVKALLDNKRPVSYAEIDAPHGHDAFLLDDPRYHNLMRAYYDRIAEEIGA

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=241, Percent_Identity=35.6846473029046, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 43101; Mature: 42970

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVALPPAALTLPNDSVGVVTPQRMHFQEPLKLRNGSSIAGYDLMVETYGTLNADRSNA
CCCCCCCCCEEECCCCCCEEECCHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCCE
VLVCHALNASHHVAGVYADDPRDVGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPM
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCC
STNPATGEPYGAAFPVVTVEDWVNAQARVADVFGITQFAAVMGGSLGGMQAVAWSLMYPQ
CCCCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHH
RLRHCIVVASTPKLSAQNIAFNEVARSSILSDPDFHGGNYYAHGVKPKRGLRVARMIGHI
HCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHH
TYLSDEDMAEKFGRELKTEDIRFSFDVEFQVESYLRYQGDKFAEYFDANTYLLITRALDY
EECCCHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHCCCHHHHHHCCCCEEEEEHHHHH
FDPALAYGGDLTRAMAQTQASFLVASFTTDWRFAPNRSRELVKALLDNKRPVSYAEIDAP
HCHHHHCCCHHHHHHHHHHHHEEEEEECCCCEECCCHHHHHHHHHHCCCCCCCEEECCCC
HGHDAFLLDDPRYHNLMRAYYDRIAEEIGA
CCCCEEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDVALPPAALTLPNDSVGVVTPQRMHFQEPLKLRNGSSIAGYDLMVETYGTLNADRSNA
CCCCCCCCEEECCCCCCEEECCHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCCE
VLVCHALNASHHVAGVYADDPRDVGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPM
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCC
STNPATGEPYGAAFPVVTVEDWVNAQARVADVFGITQFAAVMGGSLGGMQAVAWSLMYPQ
CCCCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHH
RLRHCIVVASTPKLSAQNIAFNEVARSSILSDPDFHGGNYYAHGVKPKRGLRVARMIGHI
HCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHH
TYLSDEDMAEKFGRELKTEDIRFSFDVEFQVESYLRYQGDKFAEYFDANTYLLITRALDY
EECCCHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHCCCHHHHHHCCCCEEEEEHHHHH
FDPALAYGGDLTRAMAQTQASFLVASFTTDWRFAPNRSRELVKALLDNKRPVSYAEIDAP
HCHHHHCCCHHHHHHHHHHHHEEEEEECCCCEECCCHHHHHHHHHHCCCCCCCEEECCCC
HGHDAFLLDDPRYHNLMRAYYDRIAEEIGA
CCCCEEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA