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The map label for this gene is 73539867

Identifier: 73539867

GI number: 73539867

Start: 188156

End: 189358

Strand: Reverse

Name: 73539867

Synonym: Reut_A0161

Alternate gene names: NA

Gene position: 189358-188156 (Counterclockwise)

Preceding gene: 73539868

Following gene: 73539866

Centisome position: 4.97

GC content: 66.42

Gene sequence:

>1203_bases
ATGGCCGATCGCCTGCCCATCACCGTGCTGTCCGGATATACCGGTGCCGGCAAGACCACCTTGCTGCAGCACGTCCTTGC
TGCGACAGTCGGCAAGCGCGTGGGCGTGGCTGGCAGCCTCCAGCAGGCCGGCGAGCTCGCCGTCCGTGGCGGCTTCGACC
ATCTGCTGCTCGAGCCCGCAGGCACGGACGACCCGATGGCAATCGCCGAGGCCGTGCTGTTCGAGGATGAACATGGTGGC
AGGGCCACGCTGAGTCTCGACACGCTGGTGACGGTTGTCGATGCATCGACGTTCCTGCGCGACGTCAACGATGCCGAGTT
CCTGCACGGCAGCGACGATGTGCACGACAACGGGATCGAGGAAGACGACCGCACCGTGGTCGACGTGCTGATCGCCCAAG
TCGAGTTCGCCGACGTGATCGTGCTTAACAAGTCGGATCTCGTCGACGCGAGCGCGCTGGCGCAGCTGGAGGCGATCCTT
CGCGCGCTCAACCCGCGTGCGGACATTGTCGCGGCGAGCTTCGGCAAGATTGCTGCCGAACGCGTGCTCGGCACCGGCCG
GTTCGACTTCGAAGACACCGCAAGCGCCACGGGCTGGCTGGCCCTGCAGCGTGGCGAGACGCTGCCCGAAGCACACGGCA
TCAGCGGCTTCCTCTACCGCCGTCGCCGCCCCTTCCATCCCGCACGCTTTGCCGAGCTGATCCACACCGAGTGGATGCGC
GAGCATGGCAGCGTGCTGCGTTCCAAGGGCCTGTTCTGGCTGGCGAGCCGCATGGGCATCGCAGGCGACTGGGCACAGGC
CGGAGGCGTATGCCGTCCCGCTGCGGCTGGTGCGTGGTGGGCAGCTCTCGATGCTTCCGAATGGCCGACTGATGCAGCAG
ACCTCGCAGCGCTTGAAGCCGACATGCTGGACGAAGGACAGCCTGCCGCCTACGGCGACCGCCGCCAGGAAATCGCGCTG
ATCGGCGCAGACCTCGATCGCTCCGCACTGGAGGCTTGTCTCGATGCCTGCCTGCTGACCGATGCCGAGATGGCGGCCGG
GCCCGAAGCCTGGGCCGCGTATGCCGATCCGTTCCCGGCATGGGAAGACGCCTTCGACGACGAAGATCACGATCACGATC
ACGATCACGATCATGGTCGCCACCATGGCCATGACCACCACCACGGCGGCGACTGCGACTGTGGCCATCCGCATGATCAC
TGA

Upstream 100 bases:

>100_bases
CCTGCCGGCTGTCGGGCGAAGGGCCTTTCTGGTACAGTCGCAACTTTGTTGCAATAACAGGCGCATCTCACCGGGCGCCC
TCTTTCGCGTTCACATCGCC

Downstream 100 bases:

>100_bases
GATCGCCGGGCACTTCGCCCGCCTGCGCACACGTGGTCCAGGGCTGTGGATGGCCCTGTGGCTGGCGCTGAGCCTGCTGC
TCGCACAGCATGCGGGCCTG

Product: cobalamin synthesis protein/P47K:cobalamin synthesis CobW, C-terminal

Products: NA

Alternate protein names: P47K [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MADRLPITVLSGYTGAGKTTLLQHVLAATVGKRVGVAGSLQQAGELAVRGGFDHLLLEPAGTDDPMAIAEAVLFEDEHGG
RATLSLDTLVTVVDASTFLRDVNDAEFLHGSDDVHDNGIEEDDRTVVDVLIAQVEFADVIVLNKSDLVDASALAQLEAIL
RALNPRADIVAASFGKIAAERVLGTGRFDFEDTASATGWLALQRGETLPEAHGISGFLYRRRRPFHPARFAELIHTEWMR
EHGSVLRSKGLFWLASRMGIAGDWAQAGGVCRPAAAGAWWAALDASEWPTDAADLAALEADMLDEGQPAAYGDRRQEIAL
IGADLDRSALEACLDACLLTDAEMAAGPEAWAAYADPFPAWEDAFDDEDHDHDHDHDHGRHHGHDHHHGGDCDCGHPHDH

Sequences:

>Translated_400_residues
MADRLPITVLSGYTGAGKTTLLQHVLAATVGKRVGVAGSLQQAGELAVRGGFDHLLLEPAGTDDPMAIAEAVLFEDEHGG
RATLSLDTLVTVVDASTFLRDVNDAEFLHGSDDVHDNGIEEDDRTVVDVLIAQVEFADVIVLNKSDLVDASALAQLEAIL
RALNPRADIVAASFGKIAAERVLGTGRFDFEDTASATGWLALQRGETLPEAHGISGFLYRRRRPFHPARFAELIHTEWMR
EHGSVLRSKGLFWLASRMGIAGDWAQAGGVCRPAAAGAWWAALDASEWPTDAADLAALEADMLDEGQPAAYGDRRQEIAL
IGADLDRSALEACLDACLLTDAEMAAGPEAWAAYADPFPAWEDAFDDEDHDHDHDHDHGRHHGHDHHHGGDCDCGHPHDH
>Mature_399_residues
ADRLPITVLSGYTGAGKTTLLQHVLAATVGKRVGVAGSLQQAGELAVRGGFDHLLLEPAGTDDPMAIAEAVLFEDEHGGR
ATLSLDTLVTVVDASTFLRDVNDAEFLHGSDDVHDNGIEEDDRTVVDVLIAQVEFADVIVLNKSDLVDASALAQLEAILR
ALNPRADIVAASFGKIAAERVLGTGRFDFEDTASATGWLALQRGETLPEAHGISGFLYRRRRPFHPARFAELIHTEWMRE
HGSVLRSKGLFWLASRMGIAGDWAQAGGVCRPAAAGAWWAALDASEWPTDAADLAALEADMLDEGQPAAYGDRRQEIALI
GADLDRSALEACLDACLLTDAEMAAGPEAWAAYADPFPAWEDAFDDEDHDHDHDHDHGRHHGHDHHHGGDCDCGHPHDH

Specific function: The presence of P47K is critical for the expression of the nitrile hydratase genes. May stabilize or activate the nitrile hydratase proteins [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 43049; Mature: 42918

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRLPITVLSGYTGAGKTTLLQHVLAATVGKRVGVAGSLQQAGELAVRGGFDHLLLEPA
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCEEEECCC
GTDDPMAIAEAVLFEDEHGGRATLSLDTLVTVVDASTFLRDVNDAEFLHGSDDVHDNGIE
CCCCHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCC
EDDRTVVDVLIAQVEFADVIVLNKSDLVDASALAQLEAILRALNPRADIVAASFGKIAAE
CCHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RVLGTGRFDFEDTASATGWLALQRGETLPEAHGISGFLYRRRRPFHPARFAELIHTEWMR
HHHCCCCCCCCCCCCCCCEEEEECCCCCCHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHH
EHGSVLRSKGLFWLASRMGIAGDWAQAGGVCRPAAAGAWWAALDASEWPTDAADLAALEA
HHHHHHHHCCHHEEHHHCCCCCCHHHHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHH
DMLDEGQPAAYGDRRQEIALIGADLDRSALEACLDACLLTDAEMAAGPEAWAAYADPFPA
HHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCC
WEDAFDDEDHDHDHDHDHGRHHGHDHHHGGDCDCGHPHDH
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADRLPITVLSGYTGAGKTTLLQHVLAATVGKRVGVAGSLQQAGELAVRGGFDHLLLEPA
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCEEEECCC
GTDDPMAIAEAVLFEDEHGGRATLSLDTLVTVVDASTFLRDVNDAEFLHGSDDVHDNGIE
CCCCHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCC
EDDRTVVDVLIAQVEFADVIVLNKSDLVDASALAQLEAILRALNPRADIVAASFGKIAAE
CCHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RVLGTGRFDFEDTASATGWLALQRGETLPEAHGISGFLYRRRRPFHPARFAELIHTEWMR
HHHCCCCCCCCCCCCCCCEEEEECCCCCCHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHH
EHGSVLRSKGLFWLASRMGIAGDWAQAGGVCRPAAAGAWWAALDASEWPTDAADLAALEA
HHHHHHHHCCHHEEHHHCCCCCCHHHHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHH
DMLDEGQPAAYGDRRQEIALIGADLDRSALEACLDACLLTDAEMAAGPEAWAAYADPFPA
HHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCC
WEDAFDDEDHDHDHDHDHGRHHGHDHHHGGDCDCGHPHDH
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2013568 [H]