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The map label for this gene is hldE [H]

Identifier: 73539811

GI number: 73539811

Start: 131528

End: 132043

Strand: Reverse

Name: hldE [H]

Synonym: Reut_A0105

Alternate gene names: 73539811

Gene position: 132043-131528 (Counterclockwise)

Preceding gene: 73539812

Following gene: 73539807

Centisome position: 3.47

GC content: 66.09

Gene sequence:

>516_bases
ATGAGAAACCTGGCCCCAGACATGTCCGTACCCGCCTTCGAATCCAAACTGACCCCGCCCGACGACGTTGCCGCGCTGGC
GGCGCGCATTGCTACGCTGCCGCGCCCGCTGGTGTTTACCAATGGCGTCTTCGACATCCTGCACCGCGGCCACGCCACCT
ACCTGGCCCAGGCGCGCGAACTTGGCGCCAGCCTGGTCGTGGGCGTCAACAGCGACGCCTCGGTCAGGATGCTTGGCAAG
GGCGACGACCGCCCGCTGAACCATGAATCCGACCGCATGGCGCTGCTGGCCGCGCTGGCATCAGTCGACCTGGTGGCGAT
GTTCCGCGAGCAGACCCCGGTGGAGCTGATCCGCCAGGTGCGTCCCGATATCTATGTGAAAGGCGGCGACTACGACATCG
ACACGCTCGAAGAAACGCGCCTGGTGCGCAGCTGGGGCGGCACGGCGATTGCCATCCCGTTCCTGCACGACCGCTCGACC
ACCAAGCTGCTGACCAAGGTCAGGCAGCATGGCTGA

Upstream 100 bases:

>100_bases
GCGGCCACGATGCCGCTGCCGGCCAATGACGCGCTGCTGCCGCTGTTGCGCGCAGGCTGATCCGGCCGCAGCGTCGCCAA
GCCGGGGTACCATTCCGGGG

Downstream 100 bases:

>100_bases
GCGCCTTCAGGCGGCGCCGCAGGCCAGCAACGTTTCGGCGCCGTAGCGCTGCCGCATGTCATTGAGCCGGGCGCGCGCCG
CGTCGTCGGCGCCGCGCACG

Product: cytidyltransferase-like protein

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MRNLAPDMSVPAFESKLTPPDDVAALAARIATLPRPLVFTNGVFDILHRGHATYLAQARELGASLVVGVNSDASVRMLGK
GDDRPLNHESDRMALLAALASVDLVAMFREQTPVELIRQVRPDIYVKGGDYDIDTLEETRLVRSWGGTAIAIPFLHDRST
TKLLTKVRQHG

Sequences:

>Translated_171_residues
MRNLAPDMSVPAFESKLTPPDDVAALAARIATLPRPLVFTNGVFDILHRGHATYLAQARELGASLVVGVNSDASVRMLGK
GDDRPLNHESDRMALLAALASVDLVAMFREQTPVELIRQVRPDIYVKGGDYDIDTLEETRLVRSWGGTAIAIPFLHDRST
TKLLTKVRQHG
>Mature_171_residues
MRNLAPDMSVPAFESKLTPPDDVAALAARIATLPRPLVFTNGVFDILHRGHATYLAQARELGASLVVGVNSDASVRMLGK
GDDRPLNHESDRMALLAALASVDLVAMFREQTPVELIRQVRPDIYVKGGDYDIDTLEETRLVRSWGGTAIAIPFLHDRST
TKLLTKVRQHG

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=133, Percent_Identity=48.8721804511278, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011914
- InterPro:   IPR000943
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 18740; Mature: 18740

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNLAPDMSVPAFESKLTPPDDVAALAARIATLPRPLVFTNGVFDILHRGHATYLAQARE
CCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCHHHHHHHHH
LGASLVVGVNSDASVRMLGKGDDRPLNHESDRMALLAALASVDLVAMFREQTPVELIRQV
CCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
RPDIYVKGGDYDIDTLEETRLVRSWGGTAIAIPFLHDRSTTKLLTKVRQHG
CCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRNLAPDMSVPAFESKLTPPDDVAALAARIATLPRPLVFTNGVFDILHRGHATYLAQARE
CCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCHHHHHHHHH
LGASLVVGVNSDASVRMLGKGDDRPLNHESDRMALLAALASVDLVAMFREQTPVELIRQV
CCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
RPDIYVKGGDYDIDTLEETRLVRSWGGTAIAIPFLHDRSTTKLLTKVRQHG
CCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]