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The map label for this gene is regX3 [H]

Identifier: 73539766

GI number: 73539766

Start: 74665

End: 75372

Strand: Direct

Name: regX3 [H]

Synonym: Reut_A0060

Alternate gene names: 73539766

Gene position: 74665-75372 (Clockwise)

Preceding gene: 73539764

Following gene: 73539771

Centisome position: 1.96

GC content: 64.83

Gene sequence:

>708_bases
ATGGGAAAGACGATTGCCTCGCTGGAAGCCGATCCCGTCCACGCGGCGCTGATCCGCCGGATCGTCAATGAAGCCGGATA
CGAATGCGTGAGCTTCAGCCAGAGCCGACGCCTGTTGCTCGCCCTGCATGACACCGCGTTCGACTTGCTGCTGCTTGACT
GGGACATGCCCGGCATGTCCGGGCGCGAGGTACTGAACTGGTTACGCGGCAACCTGGACCGGCGCATCCCGGTGATGTTT
CTTTCGTCCCGCGATGCCGAAGCCGACATTGTCAGCGCGCTCGTCGCCGGCGCCGATGACTATATGGCCAAGCCGATCCG
CGCCGCCGAGCTGTCGGCACGAATCGGGGCGGTGCTGCGCCGATCCAGCCCTGACAACGTCGCGCGCAACGCGCCGCTGC
GCCTGGCCGGCTATGTGTTTGACTGCGCCGCGCGGCAGGTGACCTGCCACGGCCATCCAATCTGCCTGACGCCAAAGGAA
TTCGACCTGGCCGTGCTGTTGTTCCGCAATGAAGGGCGCATCGTCACGCGTGACCACATCATCGCCACGGTCTGGGGCCG
CGAGATCTCGCCGCTGTCACGCACCATCGATACGCATGTCTCGCGCGTGCGCAGCAAGCTGGGCCTGCATGCAAGGAATG
GACTCAGGCTGACGCCGGTCTATACGCATGGGTACCGGCTGGAGCTGGCGGAGAGTGAGGCGGCATGA

Upstream 100 bases:

>100_bases
ATTGTTGAAAGCTGGAATTCGATTTGAGGCCCATCCTATTCGGACGTCCCGGCTGGCGGTTTCTAATGCCCTCTCGCGCA
AACGCTGAGAGAGACAGACC

Downstream 100 bases:

>100_bases
AGACGTCCAGGTGGACCGGTTGGTCATCCTGCGTCTGCCAAATAAAAAAAGGCACCTGAAGGTGCCTTTCGCCAAACAAC
TGACTGATCGGGGAGCGATC

Product: response regulator receiver:transcriptional regulatory protein, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MGKTIASLEADPVHAALIRRIVNEAGYECVSFSQSRRLLLALHDTAFDLLLLDWDMPGMSGREVLNWLRGNLDRRIPVMF
LSSRDAEADIVSALVAGADDYMAKPIRAAELSARIGAVLRRSSPDNVARNAPLRLAGYVFDCAARQVTCHGHPICLTPKE
FDLAVLLFRNEGRIVTRDHIIATVWGREISPLSRTIDTHVSRVRSKLGLHARNGLRLTPVYTHGYRLELAESEAA

Sequences:

>Translated_235_residues
MGKTIASLEADPVHAALIRRIVNEAGYECVSFSQSRRLLLALHDTAFDLLLLDWDMPGMSGREVLNWLRGNLDRRIPVMF
LSSRDAEADIVSALVAGADDYMAKPIRAAELSARIGAVLRRSSPDNVARNAPLRLAGYVFDCAARQVTCHGHPICLTPKE
FDLAVLLFRNEGRIVTRDHIIATVWGREISPLSRTIDTHVSRVRSKLGLHARNGLRLTPVYTHGYRLELAESEAA
>Mature_234_residues
GKTIASLEADPVHAALIRRIVNEAGYECVSFSQSRRLLLALHDTAFDLLLLDWDMPGMSGREVLNWLRGNLDRRIPVMFL
SSRDAEADIVSALVAGADDYMAKPIRAAELSARIGAVLRRSSPDNVARNAPLRLAGYVFDCAARQVTCHGHPICLTPKEF
DLAVLLFRNEGRIVTRDHIIATVWGREISPLSRTIDTHVSRVRSKLGLHARNGLRLTPVYTHGYRLELAESEAA

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=206, Percent_Identity=35.9223300970874, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=32.1739130434783, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082012, Length=187, Percent_Identity=36.3636363636364, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1790860, Length=214, Percent_Identity=32.2429906542056, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367329, Length=157, Percent_Identity=36.3057324840764, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789809, Length=195, Percent_Identity=30.2564102564103, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790552, Length=183, Percent_Identity=31.6939890710383, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786784, Length=187, Percent_Identity=31.5508021390374, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786911, Length=194, Percent_Identity=32.9896907216495, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=29.3333333333333, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787375, Length=208, Percent_Identity=27.8846153846154, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787229, Length=214, Percent_Identity=27.1028037383178, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=24.8908296943231, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693140, Length=187, Percent_Identity=29.4117647058824, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26061; Mature: 25930

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKTIASLEADPVHAALIRRIVNEAGYECVSFSQSRRLLLALHDTAFDLLLLDWDMPGMS
CCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCEEEEEEECCCCCCC
GREVLNWLRGNLDRRIPVMFLSSRDAEADIVSALVAGADDYMAKPIRAAELSARIGAVLR
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHH
RSSPDNVARNAPLRLAGYVFDCAARQVTCHGHPICLTPKEFDLAVLLFRNEGRIVTRDHI
CCCCCCHHHCCCEEEEHHHHHHHCCEEEECCCEEEECCCCCCEEEEEEECCCCEEECCCE
IATVWGREISPLSRTIDTHVSRVRSKLGLHARNGLRLTPVYTHGYRLELAESEAA
EEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEECCCCCC
>Mature Secondary Structure 
GKTIASLEADPVHAALIRRIVNEAGYECVSFSQSRRLLLALHDTAFDLLLLDWDMPGMS
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCEEEEEEECCCCCCC
GREVLNWLRGNLDRRIPVMFLSSRDAEADIVSALVAGADDYMAKPIRAAELSARIGAVLR
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHH
RSSPDNVARNAPLRLAGYVFDCAARQVTCHGHPICLTPKEFDLAVLLFRNEGRIVTRDHI
CCCCCCHHHCCCEEEEHHHHHHHCCEEEECCCEEEECCCCCCEEEEEEECCCCEEECCCE
IATVWGREISPLSRTIDTHVSRVRSKLGLHARNGLRLTPVYTHGYRLELAESEAA
EEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA