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The map label for this gene is ycgM [C]

Identifier: 73539756

GI number: 73539756

Start: 64523

End: 65365

Strand: Direct

Name: ycgM [C]

Synonym: Reut_A0050

Alternate gene names: 73539756

Gene position: 64523-65365 (Clockwise)

Preceding gene: 73539755

Following gene: 73539757

Centisome position: 1.7

GC content: 67.5

Gene sequence:

>843_bases
ATGAAACTGGTAAGAACTGGCCAGCCCGGCGCCGAGCGCCCGGGCCTGATCGACGCGCAGGGCAAGGTACGCGACCTGTC
GGGCGTGGTGACCGACATCAATGCGGCGCAGCTCTCGCCGGAAGCGCTCGCGCGCCTGGCGCAGGTGGACGCCGGCAAGT
TGCCGGTCGTTGAGGGCGCGCGCTTTGGCGTGCCCTGGACCGGTATCGGCAAGATCATCGCGATTGGCCTGAACTATGCG
GACCACGCCGCCGAAGCCGGCATGCCGCTGCCCGCCGAGCCGATCGTCTTCCTGAAGGCCAACAGCTCGCTCAACGGCCC
GGACGACGACGTGATGCTGCCGCACGGTTCGCTGAAGTCCGACTGGGAAGTCGAGCTAGGCGTGGTGATCGGCACGACCG
CGCGCAATGTCACGCGCGAGGACGCGCTGAGCCACGTGGCGGGCTACTGCGTGGTCAACGATGTGTCGGAGCGCGAGTTC
CAGATCGAGCGTGGCGGCACCTGGGACAAGGGCAAGGGCTGCGACACGTTCTGTCCGGTCGGCCCGTGGCTGGTGACGCG
CGACGAAGTGCCTGACCCGCAGGCGCTTGGTCTGTGGCTGGAGGTCAATGGCGAGCGCGTACAGAAAGGCAGCACCTCGA
CCATGGTGTTCGACGTCGCCACGGTGGTCAGCTACGTCAGCCGCTTCATGACGCTGCAACCGGGCGACCTCATCGCCACG
GGTACGCCGCCGGGCGTGGGCATGGGCTTCAAGCCGCCGCGCTTCCTGAAGGCCGGCGACACGATGCGGCTCGGCATTGA
AGGGCTTGGCGTGCAGACGCAGAAGGTCGTCGCGTACGAGTGA

Upstream 100 bases:

>100_bases
GCCGGCATTCCGAGAACACCGCCAAAGAAGTGCTGACCGTGGTCGCGCGCTCGCTCGCAGGCGAGGCCGTCCGCCAAGCC
AATCCATCGAAGGGAAAACA

Downstream 100 bases:

>100_bases
TGTGCGCAGGGCGGGCGTACAAGGCGCCCGCCAAGGTTCCCCATCGAAACGCTTTTATACAAACCGTTGGGTTTCCATAC
AAAGCGTGCCATGAGAGCAA

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKLVRTGQPGAERPGLIDAQGKVRDLSGVVTDINAAQLSPEALARLAQVDAGKLPVVEGARFGVPWTGIGKIIAIGLNYA
DHAAEAGMPLPAEPIVFLKANSSLNGPDDDVMLPHGSLKSDWEVELGVVIGTTARNVTREDALSHVAGYCVVNDVSEREF
QIERGGTWDKGKGCDTFCPVGPWLVTRDEVPDPQALGLWLEVNGERVQKGSTSTMVFDVATVVSYVSRFMTLQPGDLIAT
GTPPGVGMGFKPPRFLKAGDTMRLGIEGLGVQTQKVVAYE

Sequences:

>Translated_280_residues
MKLVRTGQPGAERPGLIDAQGKVRDLSGVVTDINAAQLSPEALARLAQVDAGKLPVVEGARFGVPWTGIGKIIAIGLNYA
DHAAEAGMPLPAEPIVFLKANSSLNGPDDDVMLPHGSLKSDWEVELGVVIGTTARNVTREDALSHVAGYCVVNDVSEREF
QIERGGTWDKGKGCDTFCPVGPWLVTRDEVPDPQALGLWLEVNGERVQKGSTSTMVFDVATVVSYVSRFMTLQPGDLIAT
GTPPGVGMGFKPPRFLKAGDTMRLGIEGLGVQTQKVVAYE
>Mature_280_residues
MKLVRTGQPGAERPGLIDAQGKVRDLSGVVTDINAAQLSPEALARLAQVDAGKLPVVEGARFGVPWTGIGKIIAIGLNYA
DHAAEAGMPLPAEPIVFLKANSSLNGPDDDVMLPHGSLKSDWEVELGVVIGTTARNVTREDALSHVAGYCVVNDVSEREF
QIERGGTWDKGKGCDTFCPVGPWLVTRDEVPDPQALGLWLEVNGERVQKGSTSTMVFDVATVVSYVSRFMTLQPGDLIAT
GTPPGVGMGFKPPRFLKAGDTMRLGIEGLGVQTQKVVAYE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=230, Percent_Identity=50, Blast_Score=225, Evalue=3e-59,
Organism=Homo sapiens, GI40786394, Length=230, Percent_Identity=49.1304347826087, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI13654274, Length=220, Percent_Identity=37.7272727272727, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI215422413, Length=213, Percent_Identity=37.5586854460094, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI66348062, Length=213, Percent_Identity=37.5586854460094, Blast_Score=145, Evalue=6e-35,
Organism=Escherichia coli, GI1787428, Length=220, Percent_Identity=34.0909090909091, Blast_Score=134, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17557057, Length=199, Percent_Identity=35.678391959799, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324161, Length=213, Percent_Identity=30.9859154929577, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28572127, Length=288, Percent_Identity=42.3611111111111, Blast_Score=195, Evalue=3e-50,
Organism=Drosophila melanogaster, GI28571789, Length=211, Percent_Identity=41.7061611374408, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24663695, Length=280, Percent_Identity=33.2142857142857, Blast_Score=146, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 29748; Mature: 29748

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVRTGQPGAERPGLIDAQGKVRDLSGVVTDINAAQLSPEALARLAQVDAGKLPVVEGA
CCCEECCCCCCCCCCEECCCCCHHHHHHHEECCCHHHCCHHHHHHHHHCCCCCCCEECCC
RFGVPWTGIGKIIAIGLNYADHAAEAGMPLPAEPIVFLKANSSLNGPDDDVMLPHGSLKS
CCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCC
DWEVELGVVIGTTARNVTREDALSHVAGYCVVNDVSEREFQIERGGTWDKGKGCDTFCPV
CCEEEEEEEEECCCCCCHHHHHHHHHHCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCC
GPWLVTRDEVPDPQALGLWLEVNGERVQKGSTSTMVFDVATVVSYVSRFMTLQPGDLIAT
CCEEEECCCCCCCCCEEEEEEECCCEECCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEC
GTPPGVGMGFKPPRFLKAGDTMRLGIEGLGVQTQKVVAYE
CCCCCCCCCCCCCCCEECCCEEEEEEECCCCEEEEEEEEC
>Mature Secondary Structure
MKLVRTGQPGAERPGLIDAQGKVRDLSGVVTDINAAQLSPEALARLAQVDAGKLPVVEGA
CCCEECCCCCCCCCCEECCCCCHHHHHHHEECCCHHHCCHHHHHHHHHCCCCCCCEECCC
RFGVPWTGIGKIIAIGLNYADHAAEAGMPLPAEPIVFLKANSSLNGPDDDVMLPHGSLKS
CCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCC
DWEVELGVVIGTTARNVTREDALSHVAGYCVVNDVSEREFQIERGGTWDKGKGCDTFCPV
CCEEEEEEEEECCCCCCHHHHHHHHHHCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCC
GPWLVTRDEVPDPQALGLWLEVNGERVQKGSTSTMVFDVATVVSYVSRFMTLQPGDLIAT
CCEEEECCCCCCCCCEEEEEEECCCEECCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEC
GTPPGVGMGFKPPRFLKAGDTMRLGIEGLGVQTQKVVAYE
CCCCCCCCCCCCCCCEECCCEEEEEEECCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA