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The map label for this gene is dnaA [H]

Identifier: 161611268

GI number: 161611268

Start: 265

End: 2019

Strand: Direct

Name: dnaA [H]

Synonym: Reut_A0001

Alternate gene names: 161611268

Gene position: 265-2019 (Clockwise)

Preceding gene: NA

Following gene: 73539708

Centisome position: 0.01

GC content: 63.65

Gene sequence:

>1755_bases
ATGCAAGACTTCTGGCAGGCGGCAGCCGCGCAGCTCGAGCGCGAACTGACGCCGCAACAGTTCAAAACCTGGATCAAGCC
GTTGGCGCCCGTCGGTTTCGACGAAGAAGCGCTCACGCTGCGCATTGCTGCGCCGAACCGGTTCAAGCTGGATTGGGTCA
AGAGCCAGTTTTCGGGGCGTATTACTGCCCTTGCCTGCGAATATTGGGAAGCGCAGGTCAGTGTTCACTTTGTCCTGGAT
CCTGCTGCGTCGGGCCGTGCGGCTGCATACGCGCAACCGCCGGCCGGCGGCATGGGCGGTCAGCCGGGCATGATGCCGGG
CGGAGGTGCCGACGGTCACGCAGCACCGGGTACGGGTATGCAAGGCTATCCCGGCGGTCAGCCGATGGGGCAACCCATGG
GCCAGCAGTTCGCCCAACCTGGCATGCAGCCCGGCTATGGCGAGTACCAGTCCGCCCACGGCCAGGCCGGCTATCCGCCG
GCGCAGGCGCCCTACCCTGGCCGTCCGCTGCAAGGCGGCATGCGCCAGCAGCCGGCGCCGGGTGCGCAGCATGGCGTTGA
CATGGGCGAGATCGACGTAGTCCAGATGGATCCGTCCGAAGTGGCTGCCCGCTCCTACCGCATGCAGCCGCAGCAACCTC
CCATGCAGTCGGGTCCGATGGTGCAGCACCCCGGCCCCGGCGGGCCCGGTGCGCAGCCCGGCCAGCCGAGCCAGGCCAGC
GACACCGTGCACGAGCGTTCGCGCCTGAACCCGATCCTGACGTTCGACAACTTCGTCACCGGTAAGGCCAACCAGTTGGC
GCGTGCTGCCGCCATCCAGGTCGCCAACAACCCGGGCAAGTCCTACAACCCGCTATATCTCTATGGCGGCGTGGGCCTTG
GTAAGACTCACTTGATCCACGCCATCGGCAATTTCATGCTGATGGAGAACCCGCGCGCGCGCATCCGCTACATCCACGCC
GAACAATACGTGTCCGACGTGGTGAAGGCCTACCAGCGCAAGGCGTTCGACGAGTTCAAGCGCTACTACCACTCGCTCGA
CCTGCTGCTGATCGACGATATTCAATTCTTCTCCGGCAAGAACCGCACGCAGGAAGAATTCTTCTATGCGTTCGAAGCAC
TGATCGCCAACCGGGCGCAGGTGATCATCACCAGCGATACGTACCCGAAGGAGATCACCGGCATCGACGACCGCCTGATC
TCGCGTTTCGACTCCGGCCTGACCGTGGCCATCGAGCCGCCCGAGCTGGAAATGCGCGTGGCGATTCTGATGAAGAAGGC
CGCCGCCGAGAACGTGAGCGTGCCCGAGGAAGTCGCGTTCTTCGTCGCCAAGCACCTGCGTTCCAACGTGCGCGAGCTCG
AAGGCGCGCTGCGCAAGATCCTGGCGTTCAGCAACTTCCACGGCCGCGACATCACCATCGAAGTCACGCGTGAAGCGCTG
AAGGACCTGCTGACGGTGCAGAACCGCCAGATCTCGGTCGAGAACATCCAGAAGACCTGCGCGGATTTCTACAACATCAA
GGTCGCTGACATGTACTCGAAAAAGCGGCCTGCGAACATTGCAAGGCCGCGCCAGATCGCGATGTACCTGGCGAAGGAAC
TCACGCAGAAGAGCCTGCCGGAGATCGGCGAACTCTTCGGCGGGCGCGATCACACCACCGTGCTGCACGCGGTGCGAAAG
ATCGCCGACGAGCGGAGCAAGGACGCGCAGCTCAACCACGAACTGCACGTGCTGGAACAGACGCTCAAGGGTTGA

Upstream 100 bases:

>100_bases
CGCTGCCGGCGTTGCAGGCATGGGTACGGGGAGGGCCGGGCGGCGAGGCGCGACAGTAGCCGTGGCGCACCCTGGGGATG
CGCTAACTAAACAAAAAACA

Downstream 100 bases:

>100_bases
TCCGAGCAGCATCCCGACCCGGGAAACCGGGGCGGGCAAGTTTTGGAAAGGCCGGCCCGCGAGGCTGGCATACTGTAGGT
TCGGCGTCACTGGAGCGGTC

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MQDFWQAAAAQLERELTPQQFKTWIKPLAPVGFDEEALTLRIAAPNRFKLDWVKSQFSGRITALACEYWEAQVSVHFVLD
PAASGRAAAYAQPPAGGMGGQPGMMPGGGADGHAAPGTGMQGYPGGQPMGQPMGQQFAQPGMQPGYGEYQSAHGQAGYPP
AQAPYPGRPLQGGMRQQPAPGAQHGVDMGEIDVVQMDPSEVAARSYRMQPQQPPMQSGPMVQHPGPGGPGAQPGQPSQAS
DTVHERSRLNPILTFDNFVTGKANQLARAAAIQVANNPGKSYNPLYLYGGVGLGKTHLIHAIGNFMLMENPRARIRYIHA
EQYVSDVVKAYQRKAFDEFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEALIANRAQVIITSDTYPKEITGIDDRLI
SRFDSGLTVAIEPPELEMRVAILMKKAAAENVSVPEEVAFFVAKHLRSNVRELEGALRKILAFSNFHGRDITIEVTREAL
KDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRK
IADERSKDAQLNHELHVLEQTLKG

Sequences:

>Translated_584_residues
MQDFWQAAAAQLERELTPQQFKTWIKPLAPVGFDEEALTLRIAAPNRFKLDWVKSQFSGRITALACEYWEAQVSVHFVLD
PAASGRAAAYAQPPAGGMGGQPGMMPGGGADGHAAPGTGMQGYPGGQPMGQPMGQQFAQPGMQPGYGEYQSAHGQAGYPP
AQAPYPGRPLQGGMRQQPAPGAQHGVDMGEIDVVQMDPSEVAARSYRMQPQQPPMQSGPMVQHPGPGGPGAQPGQPSQAS
DTVHERSRLNPILTFDNFVTGKANQLARAAAIQVANNPGKSYNPLYLYGGVGLGKTHLIHAIGNFMLMENPRARIRYIHA
EQYVSDVVKAYQRKAFDEFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEALIANRAQVIITSDTYPKEITGIDDRLI
SRFDSGLTVAIEPPELEMRVAILMKKAAAENVSVPEEVAFFVAKHLRSNVRELEGALRKILAFSNFHGRDITIEVTREAL
KDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRK
IADERSKDAQLNHELHVLEQTLKG
>Mature_584_residues
MQDFWQAAAAQLERELTPQQFKTWIKPLAPVGFDEEALTLRIAAPNRFKLDWVKSQFSGRITALACEYWEAQVSVHFVLD
PAASGRAAAYAQPPAGGMGGQPGMMPGGGADGHAAPGTGMQGYPGGQPMGQPMGQQFAQPGMQPGYGEYQSAHGQAGYPP
AQAPYPGRPLQGGMRQQPAPGAQHGVDMGEIDVVQMDPSEVAARSYRMQPQQPPMQSGPMVQHPGPGGPGAQPGQPSQAS
DTVHERSRLNPILTFDNFVTGKANQLARAAAIQVANNPGKSYNPLYLYGGVGLGKTHLIHAIGNFMLMENPRARIRYIHA
EQYVSDVVKAYQRKAFDEFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEALIANRAQVIITSDTYPKEITGIDDRLI
SRFDSGLTVAIEPPELEMRVAILMKKAAAENVSVPEEVAFFVAKHLRSNVRELEGALRKILAFSNFHGRDITIEVTREAL
KDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRK
IADERSKDAQLNHELHVLEQTLKG

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=386, Percent_Identity=57.2538860103627, Blast_Score=441, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 64389; Mature: 64389

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDFWQAAAAQLERELTPQQFKTWIKPLAPVGFDEEALTLRIAAPNRFKLDWVKSQFSGR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEHHHHHHHHCCC
ITALACEYWEAQVSVHFVLDPAASGRAAAYAQPPAGGMGGQPGMMPGGGADGHAAPGTGM
EEEEEEEHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QGYPGGQPMGQPMGQQFAQPGMQPGYGEYQSAHGQAGYPPAQAPYPGRPLQGGMRQQPAP
CCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GAQHGVDMGEIDVVQMDPSEVAARSYRMQPQQPPMQSGPMVQHPGPGGPGAQPGQPSQAS
CHHHCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHH
DTVHERSRLNPILTFDNFVTGKANQLARAAAIQVANNPGKSYNPLYLYGGVGLGKTHLIH
HHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHEEECCCCCCCCCEEEECCCCCCHHHHHH
AIGNFMLMENPRARIRYIHAEQYVSDVVKAYQRKAFDEFKRYYHSLDLLLIDDIQFFSGK
HHHHHHEECCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCC
NRTQEEFFYAFEALIANRAQVIITSDTYPKEITGIDDRLISRFDSGLTVAIEPPELEMRV
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHCCCHHHHHHHHCCCCEEEECCCCHHHHH
AILMKKAAAENVSVPEEVAFFVAKHLRSNVRELEGALRKILAFSNFHGRDITIEVTREAL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHH
KDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLP
HHHHHHCCCCCCHHHHHHHHHHHHCCEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCH
EIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
HHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDFWQAAAAQLERELTPQQFKTWIKPLAPVGFDEEALTLRIAAPNRFKLDWVKSQFSGR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEHHHHHHHHCCC
ITALACEYWEAQVSVHFVLDPAASGRAAAYAQPPAGGMGGQPGMMPGGGADGHAAPGTGM
EEEEEEEHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QGYPGGQPMGQPMGQQFAQPGMQPGYGEYQSAHGQAGYPPAQAPYPGRPLQGGMRQQPAP
CCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GAQHGVDMGEIDVVQMDPSEVAARSYRMQPQQPPMQSGPMVQHPGPGGPGAQPGQPSQAS
CHHHCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHH
DTVHERSRLNPILTFDNFVTGKANQLARAAAIQVANNPGKSYNPLYLYGGVGLGKTHLIH
HHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHEEECCCCCCCCCEEEECCCCCCHHHHHH
AIGNFMLMENPRARIRYIHAEQYVSDVVKAYQRKAFDEFKRYYHSLDLLLIDDIQFFSGK
HHHHHHEECCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCC
NRTQEEFFYAFEALIANRAQVIITSDTYPKEITGIDDRLISRFDSGLTVAIEPPELEMRV
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHCCCHHHHHHHHCCCCEEEECCCCHHHHH
AILMKKAAAENVSVPEEVAFFVAKHLRSNVRELEGALRKILAFSNFHGRDITIEVTREAL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHH
KDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLP
HHHHHHCCCCCCHHHHHHHHHHHHCCEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCH
EIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
HHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA