| Definition | Streptococcus pyogenes MGAS5005 chromosome, complete genome. |
|---|---|
| Accession | NC_007297 |
| Length | 1,838,554 |
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The map label for this gene is pepXP [H]
Identifier: 71911390
GI number: 71911390
Start: 1537678
End: 1539960
Strand: Direct
Name: pepXP [H]
Synonym: M5005_Spy_1577
Alternate gene names: 71911390
Gene position: 1537678-1539960 (Clockwise)
Preceding gene: 71911389
Following gene: 71911392
Centisome position: 83.64
GC content: 39.86
Gene sequence:
>2283_bases ATGCGCTATAATCAATTTTCCTATATTCCAACTAGTCTAGAAAGAGCGGCTGAAGAATTAAAAGAATTGGGCTTTGATCT GGATCTGCAAAAAACTGCCAAAGCTAGCCTAGAAAGCTTTTTACGTAAACTCTTCTTCCACTACCCTGATAGTGATTATC CTTTAAGTCATCTAATCGCCAAAAATGACATGGACGCATTGAGCTTTTTTCAATCAGAGCAAGAGTTATCCAAAGAGGTT TTTGATTTACTGGCCCTGCAAGTCCTTGGCTTTATTCCTGGAGTTGATTTTACAGAGGCCGATGCTTTCCTTGATAAACT GGCCTTTCCTATCCACTTTGACGAAACAGAAATTATCAAGCATATCCACCACTTATTAGCGACCCGTTGTAAGTCTGGCA TGACCCTGATTGATGATTTGGTCAGCCAAGGAATGCTTACTATGGACAATGATTACCACTTCTTCAACGGTAAATCATTA GCTACCTTTGACACGTCACAGCTGATTCGAGAAGTTGTTTACGTTGAAGCACCTCTTGATACCGATCAAGATGGCCAACT TGATCTTATTAAGGTTAATATCATTCGTCCTCCATCTCAAAAACCATTACCAACTTTGATGACACCTAGTCCATACCATC AAGGTATCAATGAAGTAGCCAACGACAAAAAACTTTATCGTATGGAAAAAGAGTTAGTCGTTAAAAAAAGGAGACAAATC ACTGTCGAAGACAGGGATTTTATTCCTCTTGAGACACAGCCTTGCAAACTTCCTATAGGTCAAAATCTAGAAAGCTTTAG CTACATTAACTCCTATAGCCTCAACGATTATTTCCTCGCACGTGGGTTTGCTAATATCTATGTTTCAGGTGTGGGAACTG CTGGTTCCACTGGCTTTATGACGAGTGGAAACTATGCTCAAATTGAAAGCTTTAAAGCCGTTATTGATTGGCTAAATGGA AGAGCCACAGCCTACACCAGCCACTCAAAAACCCACCAAGTGAGAGCTGATTGGGCAAATGGTCTAGTTTGTACGACTGG AAAGTCCTACTTGGGAACTATGTCTACTGGTTTAGCCACTACAGGCGTAGACGGATTAGCCATGATTATTGCAGAATCAG CTATTTCTTCTTGGTACAACTACTACCGCGAAAATGGCTTAGTTTGTAGTCCTGGTGGCTATCCTGGAGAGGATCTAGAT GTCCTAACTGAGCTCACCTACTCGCGTAATTTATTGGCTGGCGATTATCTTCGCCATAATGATCGTTATCAAGAATTGCT AAACCAACAGTCTCAGGCGTTAGACCGACAATCTGGTGATTATAATCAATTTTGGCACGACCGCAATTACTTAAAAAATG CTCATCAAATAAAGTGTGATGTCGTTTATACTCATGGCTTACAAGACTGGAATGTCAAACCAAGACAGGTCTATGAGATT TTCAATGCGCTTCCTTCCACAATCAACAAGCACCTCTTTTTACATCAAGGTGAGCATGTTTACATGCATAATTGGCAATC CATTGATTTTCGCGAAAGCATGAATGCCCTTTTATGTCAAAAACTCTTAGGCCTAGCTAATGATTTTAGCCTTCCTGAAA TGATCTGGCAGGATAACACCTGCCCACAAAACTGGCAGGAGCGTAAAGTCTTTGGAACCTCAACCATCAAAGAGCTTGAC CTCGGTCAGGAACTGCTTTTAATTGATAATCACTATGGTGAAGATGAATTTAAAGCTTACGGTAAAGATTTCCGTGCGTT CAAAGCAGCTCTCTTTAAAGGCAAGGCCAATCAAGCCCTGATTGATATTTTACTGGAAGAGGACTTACCTATTAACGGTG AAATTGTCCTACAGTTAAAAGTGAAATCAAGTGAAAATAAAGGACTTCTATCTGCACAAATCCTTGACTATGGTAAGAAA AAACGCTTGGGCGATCTTCCTATTGCTCTCACCCAATCAAGTATTGACAATGGGCAAAATTTCTCTAGGGAACCCCTTAA AGAGCTACCATTTAGAGAAGATTCTTACCGTGTTATTTCGAAAGGTTTCATGAATTTACAAAATCGCAATAATTTGTCGT CAATTGAAACTATTCCTAATAATAAATGGATGACTGTTAGACTTCCTTTGCAACCAACCATCTATCATCTAGAAAAAGGA GATACCCTTCGAGTCATCTTATACACAACCGATTTTGAACATACTGTCCGTGACAACAGCAACTATGCTTTAACTATCGA TCTCAGTCAGTCTCAATTGATTGTGCCAATAGCATCAAATTAA
Upstream 100 bases:
>100_bases AAAAAACATCATTCGCATTGATAAACAACATATTATCATTACCAATCTTGATAAATTAAAAGATAATATCGTTTTCTAAG CCACTAGAAAGGAAACTCCT
Downstream 100 bases:
>100_bases CAAAGAAAAGTGCTTAGCAATATAACTAAGCACTTTTTTGTTAATTGGTCTTACTAATAGCAAACAGAAAACGATCGTCT TAGTTCATAAATTCCGAATC
Product: x-prolyl-dipeptidyl aminopeptidase
Products: NA
Alternate protein names: X-Pro dipeptidyl-peptidase; X-prolyl-dipeptidyl aminopeptidase; X-PDAP [H]
Number of amino acids: Translated: 760; Mature: 760
Protein sequence:
>760_residues MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEV FDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPPSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGNYAQIESFKAVIDWLNG RATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLD VLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI FNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELD LGQELLLIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKK KRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
Sequences:
>Translated_760_residues MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEV FDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPPSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGNYAQIESFKAVIDWLNG RATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLD VLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI FNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELD LGQELLLIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKK KRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN >Mature_760_residues MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEV FDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPPSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGNYAQIESFKAVIDWLNG RATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLD VLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI FNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELD LGQELLLIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKK KRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
Specific function: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S15 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008979 - InterPro: IPR013736 - InterPro: IPR008252 - InterPro: IPR000383 - InterPro: IPR015251 [H]
Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C; PF09168 PepX_N [H]
EC number: =3.4.14.11 [H]
Molecular weight: Translated: 86708; Mature: 86708
Theoretical pI: Translated: 5.42; Mature: 5.42
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKLFFHYPDSDYPLSHLIA CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH KNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIK CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCHHHHHH HIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSLATFDTSQLIREVVYVEAPLD HHHHHHHHHHHCCCHHHHHHHHCCCEEECCCEEEECCCEEEEECHHHHHHHHHEEECCCC TDQDGQLDLIKVNIIRPPSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI CCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCE TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFM EECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCCCCE TSGNYAQIESFKAVIDWLNGRATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLAT ECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEHHHHCCCEEEECCCHHHHHHHCCCHH TGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLAGDYLRHN CCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHCC DRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI HHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH FNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNT HHHHHHHHHCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCC CPQNWQERKVFGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRAFKAALFKGKANQAL CCCCHHHCEECCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH IDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQN HHHHHHCCCCCCCEEEEEEEEECCCCCCCEEHHHHHCCCCCCCCCCCEEEECCCCCCCCC FSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG CCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCEEEEECCC DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN CEEEEEEEECCCCHHHCCCCCEEEEEEECCCEEEEEECCC >Mature Secondary Structure MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKLFFHYPDSDYPLSHLIA CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH KNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIK CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCHHHHHH HIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSLATFDTSQLIREVVYVEAPLD HHHHHHHHHHHCCCHHHHHHHHCCCEEECCCEEEECCCEEEEECHHHHHHHHHEEECCCC TDQDGQLDLIKVNIIRPPSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI CCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCE TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFM EECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCCCCE TSGNYAQIESFKAVIDWLNGRATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLAT ECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEHHHHCCCEEEECCCHHHHHHHCCCHH TGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLAGDYLRHN CCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHCC DRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI HHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH FNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNT HHHHHHHHHCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCC CPQNWQERKVFGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRAFKAALFKGKANQAL CCCCHHHCEECCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH IDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQN HHHHHHCCCCCCCEEEEEEEEECCCCCCCEEHHHHHCCCCCCCCCCCEEEECCCCCCCCC FSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG CCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCEEEEECCC DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN CEEEEEEEECCCCHHHCCCCCEEEEEEECCCEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11296296 [H]