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The map label for this gene is spi [H]

Identifier: 71911378

GI number: 71911378

Start: 1523490

End: 1524083

Strand: Direct

Name: spi [H]

Synonym: M5005_Spy_1565

Alternate gene names: 71911378

Gene position: 1523490-1524083 (Clockwise)

Preceding gene: 71911377

Following gene: 71911379

Centisome position: 82.86

GC content: 36.7

Gene sequence:

>594_bases
ATGAAACAGTTTATTAAAGAATGGGGCCCATTCACTCTCTTTTTAATTCTCTTTGGTCTATCTCGTCTTTTTTTGTGGCA
GGCTGTTAAAGTAGACGGCCATTCTATGGACCCAACTCTAGCTCATGGCGAACGCCTTATCGTTTTTAATCAAGCTAGAA
TTGATCGCTTTGATATTGTAGTTGCTCAGGAAGAAGAAAACGGACAAAAGAAAGAAATCGTAAAAAGAGTTATTGGATTG
CCAGGCGATACCATTTCTTATAATGATGACACACTTTATATTAATGGTAAAAAAACAGTTGAGCCGTATTTGGCTGAGTA
TCTAAAACAATTTAAAAACGATAAACTCCAAAAAACTTACGCCTATAATACCCTATTCCAACAGTTAGCAGAAACATCTG
ATGCTTTTACAACTAATTCTGAGGGACAAACACGCTTTGAGATGAGTGTTCCAAAAGGAGAATACCTTCTTCTTGGTGAT
GATCGTATTGTTTCCAGGGATAGTCGCGAAGTTGGTAGTTTCAAAAAAGAAAACCTTATCGGTGAAGTGAAAGCTCGTTT
TTGGCCACTCAATAAAATGACCGTTTTTAATTAG

Upstream 100 bases:

>100_bases
TTAGCCGCTTATGGTATGTCTAGCTTAGAATATAGTGCTAAACTTCACTTCGCCAACACTCACAAAGCGCAAGCGCTTCT
CACTAAATAAAAGGAATCAT

Downstream 100 bases:

>100_bases
AAAAAACCTGCCTTTGGGCAGGTTTTCAGTTATCTTGTATAAATAGAAAGAGTTACTATGGAATACGTTTTTACAGGTAC
TGTTGATCGTATCATTTTTG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGERLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGL
PGDTISYNDDTLYINGKKTVEPYLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN

Sequences:

>Translated_197_residues
MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGERLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGL
PGDTISYNDDTLYINGKKTVEPYLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN
>Mature_197_residues
MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGERLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGL
PGDTISYNDDTLYINGKKTVEPYLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 22817; Mature: 22817

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGERLIVFNQARIDRFDIV
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEEEECCCCCEEEEE
VAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEPYLAEYLKQFKNDKLQKTY
EEECCCCCCHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHH
AYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGDDRIVSRDSREVGSFKKENLI
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEECCCCEECCCCHHHCCHHHHHHH
GEVKARFWPLNKMTVFN
HHHHHHEECCCCEEECC
>Mature Secondary Structure
MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGERLIVFNQARIDRFDIV
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEEEECCCCCEEEEE
VAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEPYLAEYLKQFKNDKLQKTY
EEECCCCCCHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHH
AYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGDDRIVSRDSREVGSFKKENLI
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEECCCCEECCCCHHHCCHHHHHHH
GEVKARFWPLNKMTVFN
HHHHHHEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272867; 11463916 [H]