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The map label for this gene is mlhB [H]

Identifier: 71911220

GI number: 71911220

Start: 1378067

End: 1379053

Strand: Direct

Name: mlhB [H]

Synonym: M5005_Spy_1407

Alternate gene names: 71911220

Gene position: 1378067-1379053 (Clockwise)

Preceding gene: 71911215

Following gene: 71911228

Centisome position: 74.95

GC content: 38.3

Gene sequence:

>987_bases
TTGAAACATCCTATTCGAAAAACACTTGTCACCTTAGGTCTATTACTGACCTTATGCCTGCCGACTCCAGTTGCAGCTAG
TTCTCGTTCTTGGAAGAGCTGGTTTATCGAGCAATATTTCTGGTTAAAACGTGACAAGAGTTACTATTCTAAACAAGATG
ACCCAAGCTTCCAAAGATACCTTGATGCCTGTCGTGAACAATCTGATAAACCTTATCAACTAGATACTAATTTAGTCAAT
GGTCCCCTTGTTCAAGAAAATCTTTATGGCATGCAGGTTTACTCTTGGAATGATAATGGAAAACCTGATCAAAAAACAAT
TATTTATCTTGCCGGTGGTTCTTATCTTAACAATCCAACGACATACCATATTAATATGTTAAAGACATTATCCACAAGTC
TTGACGCTAAAATTGTTTTACCCATTTATCCTAAAGCCCCACGTTATACCTATAACTATACTATGCCAAAATTGGTCAAT
CTTTACCAACACTATTACCATAAAAATCAGAATGTTTTCCTTATGGGAGATTCAGCAGGTGGAGGTTTAGCCTTAGGTCT
AGCTCATGCCCTACACAATGAATCAGTCCCTCAACCAAAGCAGCTCGTTCTTTTATCACCTTGGTTAGATGTTACTATGT
CACACCCAGAGATTCCAGAATACGAAGATGCTGATCCTATTCTATCTTCTTGGGGATTAAAACGAGTGGGAGAATTGTGG
GCCTACTCTGCTGATAATACCAACCATATTTATGTCAGTCCTAAAAATGGTCCGATCACTTATCTACCACCAATTACTTT
ATTTACTGGGACACGAGAGATCTTTTATCCTGATATTCGCGATTATGCCGCAAAACTGAAAGCCGCTAACCACAATATTA
CCTTTATTACCCAAGAAGGCATGAACCACGTTTACCCAATTTATCCTATCGAAGAGGCAAAAACAGCTCAATACCAAATC
ATTGATGCCATCAACAAAACTCCTTAA

Upstream 100 bases:

>100_bases
AAATAACTTTTCTCATTTTTCTATCCTTATATTGACAAATGAATCGTTTTTACTATAATATTATTGCAATAAAAATAACA
TTTACATTAAGGAGATACCC

Downstream 100 bases:

>100_bases
TGAGGGGAATAACTCCTACCTGCCACCAGTTAATCTGGTGTTTTTTTTGTAGTTTGCACCACAAAATAACAATTAAAAAG
AGCCCTATCATAATGATAAG

Product: esterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKHPIRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKRDKSYYSKQDDPSFQRYLDACREQSDKPYQLDTNLVN
GPLVQENLYGMQVYSWNDNGKPDQKTIIYLAGGSYLNNPTTYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVN
LYQHYYHKNQNVFLMGDSAGGGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEIPEYEDADPILSSWGLKRVGELW
AYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFYPDIRDYAAKLKAANHNITFITQEGMNHVYPIYPIEEAKTAQYQI
IDAINKTP

Sequences:

>Translated_328_residues
MKHPIRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKRDKSYYSKQDDPSFQRYLDACREQSDKPYQLDTNLVN
GPLVQENLYGMQVYSWNDNGKPDQKTIIYLAGGSYLNNPTTYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVN
LYQHYYHKNQNVFLMGDSAGGGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEIPEYEDADPILSSWGLKRVGELW
AYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFYPDIRDYAAKLKAANHNITFITQEGMNHVYPIYPIEEAKTAQYQI
IDAINKTP
>Mature_328_residues
MKHPIRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKRDKSYYSKQDDPSFQRYLDACREQSDKPYQLDTNLVN
GPLVQENLYGMQVYSWNDNGKPDQKTIIYLAGGSYLNNPTTYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVN
LYQHYYHKNQNVFLMGDSAGGGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEIPEYEDADPILSSWGLKRVGELW
AYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFYPDIRDYAAKLKAANHNITFITQEGMNHVYPIYPIEEAKTAQYQI
IDAINKTP

Specific function: Lactone hydrolase that is required for the degradation of monocyclic monoterpenes such as menthol and carvone. Catalyzes the ring opening of lactones formed during degradation of monocyclic monoterpenes. Can hydrolyze epsilon-caprolactone, the lactone der

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.83 [H]

Molecular weight: Translated: 37561; Mature: 37561

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHPIRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKRDKSYYSKQDDPSFQRY
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCHHHHHH
LDACREQSDKPYQLDTNLVNGPLVQENLYGMQVYSWNDNGKPDQKTIIYLAGGSYLNNPT
HHHHHHCCCCCEEEECCCCCCCEECCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCE
TYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVNLYQHYYHKNQNVFLMGDSAG
EEEEEEHHHHCCCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEEECCCC
GGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEIPEYEDADPILSSWGLKRVGELW
CCHHHHHHHHHHCCCCCCCCEEEEECCCHHEEECCCCCCCCCCCCHHHHHCCHHHHHHHH
AYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFYPDIRDYAAKLKAANHNITFITQEG
EECCCCCCEEEEECCCCCEEEECCEEEEECCCCEECCCHHHHHHHHHCCCCCEEEEEECC
MNHVYPIYPIEEAKTAQYQIIDAINKTP
CCCEEEEEECCCCCCHHHHEEHHHCCCC
>Mature Secondary Structure
MKHPIRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKRDKSYYSKQDDPSFQRY
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCHHHHHH
LDACREQSDKPYQLDTNLVNGPLVQENLYGMQVYSWNDNGKPDQKTIIYLAGGSYLNNPT
HHHHHHCCCCCEEEECCCCCCCEECCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCE
TYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVNLYQHYYHKNQNVFLMGDSAG
EEEEEEHHHHCCCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEEECCCC
GGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEIPEYEDADPILSSWGLKRVGELW
CCHHHHHHHHHHCCCCCCCCEEEEECCCHHEEECCCCCCCCCCCCHHHHHCCHHHHHHHH
AYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFYPDIRDYAAKLKAANHNITFITQEG
EECCCCCCEEEEECCCCCEEEECCEEEEECCCCEECCCHHHHHHHHHCCCCCEEEEEECC
MNHVYPIYPIEEAKTAQYQIIDAINKTP
CCCEEEEEECCCCCCHHHHEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA