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The map label for this gene is cynR [C]

Identifier: 71911156

GI number: 71911156

Start: 1310905

End: 1311801

Strand: Reverse

Name: cynR [C]

Synonym: M5005_Spy_1343

Alternate gene names: 71911156

Gene position: 1311801-1310905 (Counterclockwise)

Preceding gene: 71911163

Following gene: 71911155

Centisome position: 71.35

GC content: 37.12

Gene sequence:

>897_bases
TTGGATATTAAACAAATTCGTTATTTTATCGCAATCGTTGAAAATCATTTTAACTTGAGCCAGGCGGCGGAACTGTTGTA
TGTGTCGCAGCCGACACTTAGCATGATGATCAATGATTTTGAAAAAAGAGAAAATGTTAAGCTCTTCAAACGAAAAAGAG
GTCGTATTATTGGGTTAACCTATCTTGGTGATAATTATTATAAGGACGCTCAAAAGGTTCTCAGTCTCTATGATGACATG
TTTTTGAAATTGCATGATCACAGTAAAGGGTTAAAGGGAAGTATCAATATTGGTATTCCTCCTCTTATTTTATCAGTTGT
TTTCTCAGAAGTAATGCCAAAACTGATTTTAGAAAATCCGGGGATTCAATTCAATGTTAAGGAGATTGGTGCTTACCAAC
TAAAAAATGAACTACTCGTGGGAAATGTTGACGTCGCAGTCTTGTTATCCCCAACAGGCATCGCTGATAATTTGGTTGAG
ACTTATGAAATCCAGAGATCAGAATTATCTGTATGCCTGTCTCCACGCCATCGTTTAGCTTCCAAAAAAGTTATTCAGTG
GGAAGATTTAACAGATGAACAACTTGCCCTATTTGATCCTAGTTTCACGGTTCACCATTTAGTGCTTGAAGCTTGCGAGC
GTCACCAAGTCAGACCTAATATTATTTTGACGTCCTCTTCCTGGGATTTTATGCTTAATTCTACCAAGATTAATCACAAC
GTCTTAACTATTTGTCCCAAACCTATTACAGAATTATACCAATTAAAGGACATTAAGTGTATTCCAATGGAACGTCCCAT
TTCTTGGCGTGTTGTCTTAACACGCCTCCGGAAAAAAAGTTATTCTGAAATAGAAGCCTACATCATGGACGACTTGCTAC
AGTCTTTTTTTAAGTAG

Upstream 100 bases:

>100_bases
TTTTTTTGATAGAGTTGGCAATAGCATTTAACATCTACTTGTGTCATAATATAGGTAATTATACCGGAAAAAGCAATTGA
TAAGACAAGGAGAATCCTAT

Downstream 100 bases:

>100_bases
GGTTCTCAACCACTTGGCCCAAATGTTAATTTTTTTAAAAATGAATTGGAATTGTGTAAACGCTCAATTTATGATAAACT
AAGAGATGGCTTTCTATTAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRENVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDM
FLKLHDHSKGLKGSINIGIPPLILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
TYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFTVHHLVLEACERHQVRPNIILTSSSWDFMLNSTKINHN
VLTICPKPITELYQLKDIKCIPMERPISWRVVLTRLRKKSYSEIEAYIMDDLLQSFFK

Sequences:

>Translated_298_residues
MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRENVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDM
FLKLHDHSKGLKGSINIGIPPLILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
TYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFTVHHLVLEACERHQVRPNIILTSSSWDFMLNSTKINHN
VLTICPKPITELYQLKDIKCIPMERPISWRVVLTRLRKKSYSEIEAYIMDDLLQSFFK
>Mature_298_residues
MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRENVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDM
FLKLHDHSKGLKGSINIGIPPLILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
TYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFTVHHLVLEACERHQVRPNIILTSSSWDFMLNSTKINHN
VLTICPKPITELYQLKDIKCIPMERPISWRVVLTRLRKKSYSEIEAYIMDDLLQSFFK

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=283, Percent_Identity=25.4416961130742, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787530, Length=247, Percent_Identity=25.1012145748988, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787879, Length=204, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367136, Length=227, Percent_Identity=26.431718061674, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788887, Length=248, Percent_Identity=25, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789204, Length=232, Percent_Identity=25, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34441; Mature: 34441

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRENVKLFKRKRGRIIGLT
CCHHHHHHHHHHHHCCCCHHHHHHEEEECCCHHHHHHHHHHHHCCHHHHHHCCCCEEEEE
YLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIPPLILSVVFSEVMPKLILENP
EECCCHHHHHHHHHHHHHHHHEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCC
GIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVETYEIQRSELSVCLSPRHRLA
CCEEEHHHHCHHHHCCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEECCHHHHH
SKKVIQWEDLTDEQLALFDPSFTVHHLVLEACERHQVRPNIILTSSSWDFMLNSTKINHN
CCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECEEECCC
VLTICPKPITELYQLKDIKCIPMERPISWRVVLTRLRKKSYSEIEAYIMDDLLQSFFK
EEEECCCCHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRENVKLFKRKRGRIIGLT
CCHHHHHHHHHHHHCCCCHHHHHHEEEECCCHHHHHHHHHHHHCCHHHHHHCCCCEEEEE
YLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIPPLILSVVFSEVMPKLILENP
EECCCHHHHHHHHHHHHHHHHEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCC
GIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVETYEIQRSELSVCLSPRHRLA
CCEEEHHHHCHHHHCCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEECCHHHHH
SKKVIQWEDLTDEQLALFDPSFTVHHLVLEACERHQVRPNIILTSSSWDFMLNSTKINHN
CCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECEEECCC
VLTICPKPITELYQLKDIKCIPMERPISWRVVLTRLRKKSYSEIEAYIMDDLLQSFFK
EEEECCCCHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]