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The map label for this gene is mutT [C]

Identifier: 71911054

GI number: 71911054

Start: 1197325

End: 1197780

Strand: Direct

Name: mutT [C]

Synonym: M5005_Spy_1241

Alternate gene names: 71911054

Gene position: 1197325-1197780 (Clockwise)

Preceding gene: 71911053

Following gene: 71911055

Centisome position: 65.12

GC content: 39.25

Gene sequence:

>456_bases
ATGATGATTCCAACATTTGGACATAAAAATGCACATAAAGACTATGTCACACGTTACGGTGTCTATGCTATCATTCCCAA
TCACGAACAAACAAAAATTATTCTTGTTCAAGCTCCTAATGGTTCCTGGTTTTTACCTGGTGGTGAAATTGAAGCAGGTG
AAGGTCAGCTTCAGGCCCTAGAGCGTGAACTGATTGAAGAACTTGGTTTTTCTGCTACTATTGGTTCATATTACGGTCAG
GCAGATGAATATTTCTACTCTCGCCATCGTGATACCCACTTCTACCATCCTGCCTATCTTTATGAAGTAACTGCATTTCA
AGCCGTTTCTAAGCCCTTAGAAGATTTTAATAACTTAGGTTGGTTTTCTCCTATCGAGGCAATTGCTAAATTAAAACGAG
AGAGCCATCAATGGGGAGTCAAGGAATGGCAAAAAAAGCATCATTCTACTAACTAA

Upstream 100 bases:

>100_bases
GACTCTCTCTTTTTCTATCAATTTTTTATTAAACTAAACAAATTGATAAGAATAATTAGCAAAAATTTAGTATAATGAAG
AAAAAGGAAAGGTAAATAAA

Downstream 100 bases:

>100_bases
GGCTTTAAATTAGTGCTATAATAGGTACAGGAATACTAAGGAGGACATTTATGAGACTCATCAATACCACTAGCAGTCAC
CCAGAACTCATCAAAAATCA

Product: mutator protein (7,8-dihydro-8-oxoguanine-triphosphatase)

Products: CMP; diphosphate [C]

Alternate protein names: Mutator Protein; Mut/NUDIX Family Protein; NUDIX Family Hydrolase; 7 8-Dihydro-8-Oxoguanine-Triphosphatase; MutT/NUDIX Family Protein; MutT/NUDIX Hydrolase Family Protein; MutT/NUDIX Family NTP Pyrophosphohydrolase; MutT Family Hydrolase

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWFLPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQ
ADEYFYSRHRDTHFYHPAYLYEVTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN

Sequences:

>Translated_151_residues
MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWFLPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQ
ADEYFYSRHRDTHFYHPAYLYEVTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN
>Mature_151_residues
MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWFLPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQ
ADEYFYSRHRDTHFYHPAYLYEVTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN

Specific function: Specific For Pyrimidine Substrates. Acts On 5-Methyl- Dctp, Ctp And Dctp In Decreasing Order. [C]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 17461; Mature: 17461

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWFLPGGEIEAGEGQLQAL
CCCCCCCCCCCCHHHHHHCCEEEEECCCCCEEEEEEECCCCCEECCCCCCCCCCHHHHHH
ERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYEVTAFQAVSKPLEDFNNLG
HHHHHHHCCCCCCHHHHHCCHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCC
WFSPIEAIAKLKRESHQWGVKEWQKKHHSTN
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure
MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWFLPGGEIEAGEGQLQAL
CCCCCCCCCCCCHHHHHHCCEEEEECCCCCEEEEEEECCCCCEECCCCCCCCCCHHHHHH
ERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYEVTAFQAVSKPLEDFNNLG
HHHHHHHCCCCCCHHHHHCCHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCC
WFSPIEAIAKLKRESHQWGVKEWQKKHHSTN
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; H2O [C]

Specific reaction: CTP + H2O = CMP + diphosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA