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The map label for this gene is malC [H]

Identifier: 71910877

GI number: 71910877

Start: 1034561

End: 1035868

Strand: Reverse

Name: malC [H]

Synonym: M5005_Spy_1064

Alternate gene names: 71910877

Gene position: 1035868-1034561 (Counterclockwise)

Preceding gene: 71910878

Following gene: 71910876

Centisome position: 56.34

GC content: 38.91

Gene sequence:

>1308_bases
ATGGTAGAGAACCAAAGACAACAGAAGCCTAATAAAGCCATGTGGCTATCTGTTATCCCAGGTTTGGGACAACTATACAA
TAAACAAATCGTTAAAGGGGGAGTCTTATTAGTTGTTTTCTTCCTAGAGCTACTAGAAATTGTAGTTCTAGGAATTCCTG
CTTTAACAGGTCTTTACAGTCTTGGAAGTGTTCCAATGCAAGATCACTCCTTATTTATGTTAATTAAGGGGGCCATGCAA
TTAATTACTCTAGTCTTATTTGGTATTTTTCATTTGGTTGCTATGAGAGATGCTAAATTAGTTGCACATCAAATGAATGA
AGGCAAGAAGGTTCCGGTGACGGCTAAAGAGACCCTTGAAGCGATTTATGAAAAAGGATTTCCTTACTTGCTCATCATTC
CGGCTTATTTAGCAATGGCTTTCGCTATTATTTTTCCAGTTTTAGTGACCTTGCTGATTGCTTTTACCAATTACGATTTT
AGGCATATTCCTCCGTATCGTTTATTGGATTGGGTAGGGTTGAAGAATTTTCTTAATATCTTAGAATTAAGCACCTTCAA
AACAGCATTTACATCTGTTTTGTCATGGACGCTGATCTGGACATTAGCAGCGACAAGTCTTCAAATTGTTATTGGAATTG
CAACGGCTGTTATTGCTAATCAATCCTTTATCAGAGGAAAACGTCTCTTTGGTGTGATATTCTTGTTACCATGGGCTGTT
CCAGCATTTATCTCTATTATGAGTTTTGGTAATTTCTTTAATGATTCCATTGGGGCCATGAATGTTCAGGTTCTTCCTTT
CATCGAGAAATTCCTTCCTTTCGTTGACTTCGGAATTGTGTCCTGGAAGACAGACCCCTTCTGGACAAAAGTGGCTGTTA
TTATGGTGCAAGGTTGGCTAGGATTTCCCTATATCTATATTTTGGTATCAGGTATTTTACAGGCAATTCCAGCTGATTTA
TACGAAGCAGCAACCGTTGATGGTGCGACAGTCTTACAGAAATTCCGCCATATCACCATGCCAATGATTTTTGCGGTTGC
AGCACCAACCTTTATCTCTCAGTACACCTTTAACTTCAATAATTTCTCTATTATTTATCTGTTTAATAATGGGGGCCCTG
GTACTGTGGGGGGCGGAGCTGGGACAACTGATATTCTGATTTCTTGGATTTACAAGTTGACCACACAAACCTCGCCTCAG
TTTTCGATGGCGTCGGCAGTGACCTTAATCATCTCTGTAATAGTGATTTCGGTATCGTTGATTACCTTTAAGAAATTTAA
AGCTTTTGATATGGAGGAGAGATCATGA

Upstream 100 bases:

>100_bases
CACAAACCATTACTATAAAAAAATAAATTAGTCAGCTTAAAAGGAAGTTAGTATGATAAGGAGGATAACCTTAAATCATT
TATGAGAAGAGGAATAAAAA

Downstream 100 bases:

>100_bases
GAAAGACCTATGTTTCAATATCCATGAAACGCAAACGTTTCTTCACCCAATTATTGACTTATCTCTATCTAATCTCCTTA
GTGATCGTGATTTTATTCCC

Product: maltose transporter permease

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MVENQRQQKPNKAMWLSVIPGLGQLYNKQIVKGGVLLVVFFLELLEIVVLGIPALTGLYSLGSVPMQDHSLFMLIKGAMQ
LITLVLFGIFHLVAMRDAKLVAHQMNEGKKVPVTAKETLEAIYEKGFPYLLIIPAYLAMAFAIIFPVLVTLLIAFTNYDF
RHIPPYRLLDWVGLKNFLNILELSTFKTAFTSVLSWTLIWTLAATSLQIVIGIATAVIANQSFIRGKRLFGVIFLLPWAV
PAFISIMSFGNFFNDSIGAMNVQVLPFIEKFLPFVDFGIVSWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQAIPADL
YEAATVDGATVLQKFRHITMPMIFAVAAPTFISQYTFNFNNFSIIYLFNNGGPGTVGGGAGTTDILISWIYKLTTQTSPQ
FSMASAVTLIISVIVISVSLITFKKFKAFDMEERS

Sequences:

>Translated_435_residues
MVENQRQQKPNKAMWLSVIPGLGQLYNKQIVKGGVLLVVFFLELLEIVVLGIPALTGLYSLGSVPMQDHSLFMLIKGAMQ
LITLVLFGIFHLVAMRDAKLVAHQMNEGKKVPVTAKETLEAIYEKGFPYLLIIPAYLAMAFAIIFPVLVTLLIAFTNYDF
RHIPPYRLLDWVGLKNFLNILELSTFKTAFTSVLSWTLIWTLAATSLQIVIGIATAVIANQSFIRGKRLFGVIFLLPWAV
PAFISIMSFGNFFNDSIGAMNVQVLPFIEKFLPFVDFGIVSWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQAIPADL
YEAATVDGATVLQKFRHITMPMIFAVAAPTFISQYTFNFNNFSIIYLFNNGGPGTVGGGAGTTDILISWIYKLTTQTSPQ
FSMASAVTLIISVIVISVSLITFKKFKAFDMEERS
>Mature_435_residues
MVENQRQQKPNKAMWLSVIPGLGQLYNKQIVKGGVLLVVFFLELLEIVVLGIPALTGLYSLGSVPMQDHSLFMLIKGAMQ
LITLVLFGIFHLVAMRDAKLVAHQMNEGKKVPVTAKETLEAIYEKGFPYLLIIPAYLAMAFAIIFPVLVTLLIAFTNYDF
RHIPPYRLLDWVGLKNFLNILELSTFKTAFTSVLSWTLIWTLAATSLQIVIGIATAVIANQSFIRGKRLFGVIFLLPWAV
PAFISIMSFGNFFNDSIGAMNVQVLPFIEKFLPFVDFGIVSWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQAIPADL
YEAATVDGATVLQKFRHITMPMIFAVAAPTFISQYTFNFNNFSIIYLFNNGGPGTVGGGAGTTDILISWIYKLTTQTSPQ
FSMASAVTLIISVIVISVSLITFKKFKAFDMEERS

Specific function: Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790465, Length=278, Percent_Identity=33.8129496402878, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787570, Length=258, Percent_Identity=27.906976744186, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR007829 [H]

Pfam domain/function: PF00528 BPD_transp_1; PF05154 TM2 [H]

EC number: NA

Molecular weight: Translated: 48408; Mature: 48408

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCCCCC
>Mature Secondary Structure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HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8478935; 11463916 [H]