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The map label for this gene is citE [H]

Identifier: 71910719

GI number: 71910719

Start: 892320

End: 893177

Strand: Direct

Name: citE [H]

Synonym: M5005_Spy_0906

Alternate gene names: 71910719

Gene position: 892320-893177 (Clockwise)

Preceding gene: 71910718

Following gene: 71910720

Centisome position: 48.53

GC content: 42.89

Gene sequence:

>858_bases
GTGCCTGGTGCCAATGCAGCCATGCTTCGAGATGCTCCTTTATTTGGCGCTGATTCAATCATGTTTGACTTGGAAGATTC
TGTTTCACTCAAAGAAAAAGACACCTCTAGAGCTCTCGTTCATTTTGCGCTTAAAACTTTTGATTATTCAAGCGTTGAAA
CGGTTGTTCGTGTGAATGGTCTTGATTCTTGTGGGGCTTTAGACATCGAAGCTGTTGTTTTGGCAGGTGTCAACGTGATT
CGTCTTCCAAAAACAGAGACTGCTCAAGATATTATTGATGTGGAGGCTGTTATTGAACGTGTCGAACGCGAGAACAGCAT
TGAAGTTGGTCGCACACGTATGATGGCAGCCATTGAATCAGCCGAAGGTGTCCTAAATGCTCGTGAGATTGCCAAAGCTT
CTAAGCGCTTGATTGGTATTGCTCTTGGAGCAGAAGACTATGTCACGAATATGAAAACGCGTCGTTACCCAGATGGTCAA
GAATTATTCTTTGCTCGTAGCATGATTTTACACGCTGCTCGTGCTGCTGGAATTGCTGCCATTGATACTGTTTATTCTGA
TGTCAATAATACCGAAGGGTTCCAAAACGAAGTTCGCATGATCAAACAGTTAGGATTTGATGGTAAATCGGTCATCAACC
CTCGCCAAATTCCTCTGGTCAATGAGATTTATACCCCAACAAAAAAAGAAATTGACCATGCCAAACAAGTCATCTGGGCA
ATTCGTGAAGCTGAAAGCAAAGGCTCTGGCGTTATTTCCTTAAATGGAAAAATGGTTGATAAACCAATCGTTGAACGTGC
AGAACGTGTGATTGCCCTAGCAACAGCAGCAGGTGTTTTATCTGAGGAGGATATTTAA

Upstream 100 bases:

>100_bases
AAGCGAGAACCATCGCAGCTGTTCATCGCGCTGCTGGTATTGACCAATACGATTGGAAGGAGATTGACTCATGGAACGTT
TAAGAAGAACAATGATGTTT

Downstream 100 bases:

>100_bases
AGATGGTAACAAATAAACTCGGTAGAGATATTCCTCAACCATACGCCGACCAATACGGTGTCTTTGAAGGAGAACTCGCA
AATATCAAACAGTATGACGA

Product: citrate lyase beta chain/citryl-CoA lyase subunit

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKDTSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVI
RLPKTETAQDIIDVEAVIERVERENSIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTNMKTRRYPDGQ
ELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDGKSVINPRQIPLVNEIYTPTKKEIDHAKQVIWA
IREAESKGSGVISLNGKMVDKPIVERAERVIALATAAGVLSEEDI

Sequences:

>Translated_285_residues
MPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKDTSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVI
RLPKTETAQDIIDVEAVIERVERENSIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTNMKTRRYPDGQ
ELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDGKSVINPRQIPLVNEIYTPTKKEIDHAKQVIWA
IREAESKGSGVISLNGKMVDKPIVERAERVIALATAAGVLSEEDI
>Mature_284_residues
PGANAAMLRDAPLFGADSIMFDLEDSVSLKEKDTSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVIR
LPKTETAQDIIDVEAVIERVERENSIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTNMKTRRYPDGQE
LFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDGKSVINPRQIPLVNEIYTPTKKEIDHAKQVIWAI
REAESKGSGVISLNGKMVDKPIVERAERVIALATAAGVLSEEDI

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=287, Percent_Identity=27.1777003484321, Blast_Score=121, Evalue=8e-28,
Organism=Escherichia coli, GI87081764, Length=283, Percent_Identity=57.243816254417, Blast_Score=313, Evalue=8e-87,
Organism=Caenorhabditis elegans, GI17557458, Length=289, Percent_Identity=28.0276816608997, Blast_Score=130, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 31076; Mature: 30945

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKDTSRALVHFALKTFDYSSVETVVRVNG
CCCCCCCCEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHEEEECC
LDSCGALDIEAVVLAGVNVIRLPKTETAQDIIDVEAVIERVERENSIEVGRTRMMAAIES
CCCCCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AEGVLNAREIAKASKRLIGIALGAEDYVTNMKTRRYPDGQELFFARSMILHAARAAGIAA
HHHHHHHHHHHHHHHHHEEEEECCHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
IDTVYSDVNNTEGFQNEVRMIKQLGFDGKSVINPRQIPLVNEIYTPTKKEIDHAKQVIWA
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHH
IREAESKGSGVISLNGKMVDKPIVERAERVIALATAAGVLSEEDI
HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PGANAAMLRDAPLFGADSIMFDLEDSVSLKEKDTSRALVHFALKTFDYSSVETVVRVNG
CCCCCCCEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHEEEECC
LDSCGALDIEAVVLAGVNVIRLPKTETAQDIIDVEAVIERVERENSIEVGRTRMMAAIES
CCCCCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AEGVLNAREIAKASKRLIGIALGAEDYVTNMKTRRYPDGQELFFARSMILHAARAAGIAA
HHHHHHHHHHHHHHHHHEEEEECCHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
IDTVYSDVNNTEGFQNEVRMIKQLGFDGKSVINPRQIPLVNEIYTPTKKEIDHAKQVIWA
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHH
IREAESKGSGVISLNGKMVDKPIVERAERVIALATAAGVLSEEDI
HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457870 [H]