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The map label for this gene is ywlC [H]

Identifier: 71910678

GI number: 71910678

Start: 855073

End: 855663

Strand: Direct

Name: ywlC [H]

Synonym: M5005_Spy_0865

Alternate gene names: 71910678

Gene position: 855073-855663 (Clockwise)

Preceding gene: 71910677

Following gene: 71910679

Centisome position: 46.51

GC content: 37.73

Gene sequence:

>591_bases
ATGGAGTATCTAGCTAGTATCATTGAATCAGGTGATGCCCTTGTTTTACCAACAGAAACGGTTTATGGTCTTTTTGCCAA
GGCTTTAGATGAAAAAGCAGTAAATGCTGTTTATGACTTAAAACAAAGACCCCGAGATAAAGCAATGAACCTTAATGTGG
CTGATTTTAATAGTATCTTAGCCTTTTCAAAAGAACAGCCGAGATACCTCAAGAAATTATACCAAGCCTTTTTACCAGGT
CCGTTAACGATTATTTTAAAAGCTAATGACCAGGTTCCTTATTGGATTAATTCGGGACTTTCAACGGTTGGTTTTCGCTT
ACCCAGTCATCCAATTACCGCAGCTTTAATTCAAAAAACAGGCCCTTTAATTGGTCCTTCTGCAAACTTATCTGGCAAAG
CTAGTGGTCGAGTTTTTGATCATATTATGCAAGATTTTGACTTTCAAGTGTTTGGTTATGCAGATGATCCTTTTCTAACA
GGTAAGGATTCAACCATCTTAGACTTATCAGGTGAGCGTGCTGTGATTTTACGTCAAGGTGCTATCACCAAAGAAGAATT
ATTAGCTAACGTGCCTGAACTTCGCTTTTAA

Upstream 100 bases:

>100_bases
GCTGAAGGTATAAAAGATATGTTACAAGCCTATTTTCCTCAAAGACATATACGAGCCGTAACGGATATATTTGGCAAAGA
AAGGATGGTGGTTGTTGATT

Downstream 100 bases:

>100_bases
GAGAGGAGCCGCTTGGAATGTTGAGACCATTAAGTAAAACGGACTGTCCTATGCTACAAGAAATTAATGCCAAAGCCCTT
GGCTATTTAGTTTCGCTTGA

Product: SUA5 protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRPRDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPG
PLTIILKANDQVPYWINSGLSTVGFRLPSHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
GKDSTILDLSGERAVILRQGAITKEELLANVPELRF

Sequences:

>Translated_196_residues
MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRPRDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPG
PLTIILKANDQVPYWINSGLSTVGFRLPSHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
GKDSTILDLSGERAVILRQGAITKEELLANVPELRF
>Mature_196_residues
MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRPRDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPG
PLTIILKANDQVPYWINSGLSTVGFRLPSHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
GKDSTILDLSGERAVILRQGAITKEELLANVPELRF

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=143, Percent_Identity=29.3706293706294, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI87081864, Length=184, Percent_Identity=26.6304347826087, Blast_Score=68, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=182, Percent_Identity=30.2197802197802, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=207, Percent_Identity=32.3671497584541, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 21620; Mature: 21620

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRPRDKAMNLNVADFNSIL
CHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHH
AFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLSTVGFRLPSHPITAALIQKT
HCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCHHHHEECCCCCHHHHHHHHC
GPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLTGKDSTILDLSGERAVILRQG
CCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCEECCCCCEEEEECCCEEEEEECC
AITKEELLANVPELRF
CCCHHHHHHCCCCCCC
>Mature Secondary Structure
MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRPRDKAMNLNVADFNSIL
CHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHH
AFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLSTVGFRLPSHPITAALIQKT
HCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCHHHHEECCCCCHHHHHHHHC
GPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLTGKDSTILDLSGERAVILRQG
CCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCEECCCCCEEEEECCCEEEEEECC
AITKEELLANVPELRF
CCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]