| Definition | Streptococcus pyogenes MGAS5005 chromosome, complete genome. |
|---|---|
| Accession | NC_007297 |
| Length | 1,838,554 |
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The map label for this gene is ltaS1 [H]
Identifier: 71910435
GI number: 71910435
Start: 624041
End: 626212
Strand: Reverse
Name: ltaS1 [H]
Synonym: M5005_Spy_0622
Alternate gene names: 71910435
Gene position: 626212-624041 (Counterclockwise)
Preceding gene: 71910441
Following gene: 71910429
Centisome position: 34.06
GC content: 34.99
Gene sequence:
>2172_bases GTGAAGAAATTTAAAACACTTATCACAGGTTTTATCAACACAAGATTGGGTTTTATAATTACTCTACTCTTTTGTTACTG GATAAAGACCCTGTGGGCATATCATACAGACTTTTCACTAGATTTGGGAAATATATACCAAGTCTTTCTAACTATTATCA ATCCAATCCCACTAGCTTTTTTACTTTTGGGGGTTGCTCTTTACGTTAAGAATACCCGAGCCTTTTATATCTGTTCTTGG GTGGTTTATATTATCCTTAACATTCTCTTGATATCAAATTCTATATATTACCGAGAATTTTCAGACTTTATTACAGTGAG TGCCATGCTAGCTAGTAGTAAAGTCTCCGCTGGATTAGGGGACTCTGCTTTAAACCTTTTACGCATCTGGGATATTATCT ATATTCTTGATTTTATTATTCTAATTAGTTTATCTATCGCTAAAAAAATCAAAAATGATCAACGTCCTTTTAACAAGCGC GCAGCATTTGCCATCACCGCTTTATCTAGTCTATTGCTTTCTATTAATCTTTTTTTAGCAGAAATTGATCGTCCGGAACT ATTAACACGTGGCTTTTCAAATACTTATATTGTGAGAGCTTTAGGACTACCAGCGTTTACCCTCTATAGCGGCAATCAAA CCTATCAAGCTCAAAAAGAACGAAATGGAGCTACTGCAGAAGAATTAATTGATGTTAAAACTTATGTCAAAGGACATTAT GCAGCACCTGATCCTCAGTATTTTGGAATTGGAAAAGGCAAAAATATTATTGTTCTTCATTTAGAAAGCTTTCAACAATT CTTAATAGATTATAAACTAAAAGAAGGAGATAAAGAATATGAGGTAACGCCTTTTATCAACTCACTTTATCACTCAAATG CTACCTTAGCATTCCCTAACTTTTTTCATCAGGTTAAAGCAGGTAAAACTTCTGATGCTGAAACCATGATGGAGAATTCC TTATTTGGTTTAAATAGTGGTTCTTTTATGGTGAACTACGGTGGTGAAAATACACAATTTGCTACTCCAAGTATTTTAGC CCAAAAAGGTGGCTATACCAGCGCTGTCTTTCATGGTAACGTTGGAACTTTCTGGAATCGCAATAATGCTTATAAACAAT GGGGCTATAATTATTTTTTTGATTCTAGCTACTTCTCTAAACAAAATAGTAAGAACTCTTTTCAATATGGGTTAAATGAT AAGTACATGTTTAAGGATTCCATAAAATATCTTGAACAGATGCAACAACCTTTTTATACCAAGTTTATCACTGTGAGTAA TCACTATCCTTATACTAGTCTAAAAGGCGAAAGTAGTGAAGAAGGTTTTCCTTTAGCCAAAACAGACGATGAAACGATCA ATGGTTACTTTGCTACTGCCAATTATTTAGACGCTGCCCTTAAATCTTTTTTTGATTACTTGAAAGCCACTGGTTTGTAC GACAATTCTATTTTTGTTTTATATGGTGATCATTATGGTATTTCAAATTCTCGTAATTCTAGTCTTGCTCCACTTCTTGG TAAAGATTCTGAAACTTGGTCTGAATATGATAATGCTATGCTACAACGAGTCCCGTATATGATCCATATTCCAGGTTATA CGAATGGTAGTATCAAAGAAACCTTTGGCGGTGAAATCGATGCTCTTCCTACTTTACTCCACATACTTGGTATTGACACT AGTCAGTTTGTTCAATTAGGACAAGATTTATTATCACCTCAAAATAGCCAGATTGTGGCACAACGAACATCTGGGACTTA TATGACTCCTGAATACACTAACTATAGTGGACGTCTGTACAACACGCAAACAGGTTTAGAAATCACTAATCCCGATGAAA TGACTATAGCCAAAACTAAGGAAATTCGCTCTGCTGTTGCTCAACAACTAGCAGCTAGCGACGCTATTCAAACGGGTGAT CTCCTGCGCTTTGATACTCAAAATGGTCTAAAAGCTATTGATCCTAACCAGTTTATCTACACTAAGCAGTTAAAACAACT GAAAGATATTTCAGCAAAACTCGGATCAGAGTCAACAAGTTTATACAGTAAAAATGGTCATAAATCAACTCAGAAACTTT TTAAAGCACCATCTTACTTAGAACTAAATCCCGTAGAAGCTGACGCGGCAACTTCTGAACTAAAAGAGGATAACCCCAAA AATAAAGAATAA
Upstream 100 bases:
>100_bases ACTTACAACAAGCATTAGCTTCACATTTTTGGTATAATTTAATCTGAGATTTTATTTGGAGATGACATCTTTAGGAAAAA ACGATAAGGAAGTTGCTACT
Downstream 100 bases:
>100_bases TCAATTTAATGATCTGACTAGAAGCAAAATAATAATTTTGCTTCTTTTTTATTGGCGATATTCAAGTTTATCAGTAATCA AAATATGCTAATTAGACCTA
Product: phosphoglycerol transferase
Products: NA
Alternate protein names: LTA synthase 1; Polyglycerol phosphate synthase 1 [H]
Number of amino acids: Translated: 723; Mature: 723
Protein sequence:
>723_residues MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSW VVYIILNILLISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIAKKIKNDQRPFNKR AAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHY AAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENS LFGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKNSFQYGLND KYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGESSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLY DNSIFVLYGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLLHILGIDT SQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQTGD LLRFDTQNGLKAIDPNQFIYTKQLKQLKDISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNPK NKE
Sequences:
>Translated_723_residues MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSW VVYIILNILLISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIAKKIKNDQRPFNKR AAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHY AAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENS LFGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKNSFQYGLND KYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGESSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLY DNSIFVLYGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLLHILGIDT SQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQTGD LLRFDTQNGLKAIDPNQFIYTKQLKQLKDISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNPK NKE >Mature_723_residues MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSW VVYIILNILLISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIAKKIKNDQRPFNKR AAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHY AAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENS LFGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKNSFQYGLND KYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGESSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLY DNSIFVLYGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLLHILGIDT SQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQTGD LLRFDTQNGLKAIDPNQFIYTKQLKQLKDISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNPK NKE
Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate [H]
COG id: COG1368
COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
Gene ontology:
Cell location: Processed glycerol phosphate lipoteichoic acid synthase 1:Secreted. Note=The secretion into the extracellular medium is dependent on secA and ffh [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the LTA synthase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017849 - InterPro: IPR017850 - InterPro: IPR012160 - InterPro: IPR000917 [H]
Pfam domain/function: PF00884 Sulfatase [H]
EC number: NA
Molecular weight: Translated: 81572; Mature: 81572
Theoretical pI: Translated: 7.12; Mature: 7.12
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGNIYQVFLTIINPIPLAF CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH LLLGVALYVKNTRAFYICSWVVYIILNILLISNSIYYREFSDFITVSAMLASSKVSAGLG HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC DSALNLLRIWDIIYILDFIILISLSIAKKIKNDQRPFNKRAAFAITALSSLLLSINLFLA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH EIDRPELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHY HCCCHHHHHCCCCCCEEEEEECCCEEEEECCCCCEEHHHHCCCCCHHHHHHHHHHHCCCC AAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPN CCCCCCEEECCCCCCEEEEEHHHHHHHHHHHHHCCCCCCEEECHHHHHHHCCCCEEECHH FFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGN HHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCEEEEEECC VGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYT CCCCCCCCCCHHHCCCCEEECCHHHCCCCCCCCEEECCCCCEEHHHHHHHHHHHCCCCEE KFITVSNHYPYTSLKGESSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLY EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCC DNSIFVLYGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKE CCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHH TFGGEIDALPTLLHILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLY HCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCCCEEE NTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIY ECCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHH TKQLKQLKDISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNPK HHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHCCCCCEEECCCCCCHHHHHHHCCCCC NKE CCC >Mature Secondary Structure MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGNIYQVFLTIINPIPLAF CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH LLLGVALYVKNTRAFYICSWVVYIILNILLISNSIYYREFSDFITVSAMLASSKVSAGLG HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC DSALNLLRIWDIIYILDFIILISLSIAKKIKNDQRPFNKRAAFAITALSSLLLSINLFLA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH EIDRPELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHY HCCCHHHHHCCCCCCEEEEEECCCEEEEECCCCCEEHHHHCCCCCHHHHHHHHHHHCCCC AAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPN CCCCCCEEECCCCCCEEEEEHHHHHHHHHHHHHCCCCCCEEECHHHHHHHCCCCEEECHH FFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGN HHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCEEEEEECC VGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYT CCCCCCCCCCHHHCCCCEEECCHHHCCCCCCCCEEECCCCCEEHHHHHHHHHHHCCCCEE KFITVSNHYPYTSLKGESSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLY EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCC DNSIFVLYGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKE CCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHH TFGGEIDALPTLLHILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLY HCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCCCEEE NTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIY ECCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHH TKQLKQLKDISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNPK HHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHCCCCCEEECCCCCCHHHHHHHCCCCC NKE CCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9141694; 9384377; 10658653 [H]