Click here to switch to the map view.

The map label for this gene is lip2

Identifier: 71893486

GI number: 71893486

Start: 165262

End: 166059

Strand: Reverse

Name: lip2

Synonym: MHJ_0129

Alternate gene names: NA

Gene position: 166059-165262 (Counterclockwise)

Preceding gene: 71893502

Following gene: 71893483

Centisome position: 18.5

GC content: 26.32

Gene sequence:

>798_bases
TTAGATAATTGAAATTACCCTTTTGTAATTAACAGGAATCCCTTTAGCAAAATTCATATTGTTTTTTGTCATGGTTTTAA
TTCAAATCATAACGTATTTTCAAGCACAATTGACTCAATAAGTAAAAAAATCCCACTAAATTATTATAGTTTTACTCTCC
CTGGAAATAATTTAACACCAGCTAGCGAAGACCAACTTTATTTAGAATATTATGCGGATTTAACAGTTAGTTTTATTAAA
AAATTAAATTTAAAGGAGGTTATTTTAGTCGGACATTCGATGGGAGCAGCAATTGCAGCATTAATTTATAAAAGAATCCC
TAAAATGATAGTAAAAATTGTTTTTATTGCACCAATGAATAAGGCAAACTTACCCCTAAAAGATTTTTTTTATGAAAAAT
TTTTTCCAAAAACACCAGAAGAAATGCTTGAATTTATGCCAATTTATGAATATGACAAAGAAAAATATAAAGATCCTAAA
TATTTAAAATGAGCAAAAAGTCTCTATAATTACGAGTATTTTAATAATTTTAATATTGTTTCATTAGCACAAAATCTGCT
AAAAAATAATATGATGGACCAAATTGAGCAAGCCCTAAAATCAATAAAAATCCCAACACTTTTAGTTTTAGGTCAAAGAG
ATGGAATTGTATTACAGCAAGAGACAAAAACATATTTTGAGTCACTAATTCCAAAGGTTCAAACAGAGATAATTCCTAAA
ACAGGGCATTTAATTTATAGCGAAAATCCTGAATATTTTAATCAAATTTTTAGTGACTTTATAAAAAAAACACTATAA

Upstream 100 bases:

>100_bases
TTTAATGCTAAAAAAATTAGAATAATATTATATAATTAAAATAAAAAAAATTAAGAAAAAACAAGGAAATACAATGATAA
ATTCACAAAGTAATAACATT

Downstream 100 bases:

>100_bases
AAACAAGTGTTTTTTTATAAAGCAACTTCTAAGTTTTTAAATTTTTGAAAATTAAAAACTTGGTTTTAAAAACCAAATTT
TCTTATTTTAAAATAATTTA

Product: lipase-esterase

Products: diacylglycerol; carboxylate

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MDNWNYPFVINRNPFSKIHIVFCHGFNSNHNVFSSTIDSISKKIPLNYYSFTLPGNNLTPASEDQLYLEYYADLTVSFIK
KLNLKEVILVGHSMGAAIAALIYKRIPKMIVKIVFIAPMNKANLPLKDFFYEKFFPKTPEEMLEFMPIYEYDKEKYKDPK
YLKWAKSLYNYEYFNNFNIVSLAQNLLKNNMMDQIEQALKSIKIPTLLVLGQRDGIVLQQETKTYFESLIPKVQTEIIPK
TGHLIYSENPEYFNQIFSDFIKKTL

Sequences:

>Translated_265_residues
LDN*NYPFVINRNPFSKIHIVFCHGFNSNHNVFSSTIDSISKKIPLNYYSFTLPGNNLTPASEDQLYLEYYADLTVSFIK
KLNLKEVILVGHSMGAAIAALIYKRIPKMIVKIVFIAPMNKANLPLKDFFYEKFFPKTPEEMLEFMPIYEYDKEKYKDPK
YLK*AKSLYNYEYFNNFNIVSLAQNLLKNNMMDQIEQALKSIKIPTLLVLGQRDGIVLQQETKTYFESLIPKVQTEIIPK
TGHLIYSENPEYFNQIFSDFIKKTL
>Mature_265_residues
LDN*NYPFVINRNPFSKIHIVFCHGFNSNHNVFSSTIDSISKKIPLNYYSFTLPGNNLTPASEDQLYLEYYADLTVSFIK
KLNLKEVILVGHSMGAAIAALIYKRIPKMIVKIVFIAPMNKANLPLKDFFYEKFFPKTPEEMLEFMPIYEYDKEKYKDPK
YLK*AKSLYNYEYFNNFNIVSLAQNLLKNNMMDQIEQALKSIKIPTLLVLGQRDGIVLQQETKTYFESLIPKVQTEIIPK
TGHLIYSENPEYFNQIFSDFIKKTL

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

Organism=Homo sapiens, GI189027141, Length=274, Percent_Identity=24.0875912408759, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.1.1.3

Molecular weight: Translated: 30660; Mature: 30660

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
LDNNYPFVINRNPFSKIHIVFCHGFNSNHNVFSSTIDSISKKIPLNYYSFTLPGNNLTPA
CCCCCCEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
SEDQLYLEYYADLTVSFIKKLNLKEVILVGHSMGAAIAALIYKRIPKMIVKIVFIAPMNK
CCCCEEHHHHHHHHHHHHHHCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHEECCCC
ANLPLKDFFYEKFFPKTPEEMLEFMPIYEYDKEKYKDPKYLKAKSLYNYEYFNNFNIVSL
CCCCHHHHHHHHHCCCCHHHHHHHCCHHHCCHHHCCCCCHHHHHHHCCCHHHCCCCHHHH
AQNLLKNNMMDQIEQALKSIKIPTLLVLGQRDGIVLQQETKTYFESLIPKVQTEIIPKTG
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCC
HLIYSENPEYFNQIFSDFIKKTL
CEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: triacylglycerol; H2O

Specific reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7569993 [H]