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The map label for this gene is ung [H]

Identifier: 71893483

GI number: 71893483

Start: 163634

End: 164302

Strand: Reverse

Name: ung [H]

Synonym: MHJ_0126

Alternate gene names: 71893483

Gene position: 164302-163634 (Counterclockwise)

Preceding gene: 71893486

Following gene: 71893482

Centisome position: 18.31

GC content: 27.8

Gene sequence:

>669_bases
ATTTTTGAAAATGGAATCAAAACTAAGTTTGAAAGCTTTTTTTATAATGAGTCTAAAAAAGCATATTTTCAAAAATTAAT
GGAAAAACTCGATGAAGAATATGAAAAATATCAAGTTTTTCCAAATAAAAAAGCTTTATTTCGCGCAATTGAATTAACAA
ATTTTGCAACTCTAAAAATTGTTATTATTGGCCAGGATCCTTATCATAAAAAAGGTCAAGCCGATGGACTTGCTTTTTCA
ACAAGAACAAAAATTTTGCCCCCTTCACTTCGAAATTTATTTTTGGAGATAAAAAATGCCTACCCAAACTTTTCAAAAGA
AAACGGGAATCTTGAAAACTGGGCAAAACAAGGCGTTTTATTACTTAATCACGTTTTAACCGTGCGAAAATCCAGTCCCA
ATTCACATAAAAATATTGGATGGGAGGTTTTTAGTTCTAACTTAATCAACTTTATTGTAAAAAATAAAGTTGATATTGTT
TTTTTATTATTGGGTAAAAAAGCAAAATTAGCAGTTAAAAATATTAACCTTGAAAAGCAAAAAGTTTTTGCCTATTCACA
TCCTTCGCCTTTTAGTTTCGCCAAATCGCTTAAAAATTCTATGGTTTTCCGCAAAATTAACGATTTTTTAAAAGAAAAAA
AACGATTAGAAATTAATTGGAATTTATAA

Upstream 100 bases:

>100_bases
TTCAGATTTAAACCTTTTTGGTATGAGATGGTTTGAATAAACGCTAAAATTATAGCATTTTCTCTAAAAAAAGCAATAAA
AAAATTTTTTTCTTGCTATA

Downstream 100 bases:

>100_bases
AAAAAAGTGTATAATTTTCTAAATTATATCATAAAAGAAAGGATTTTTTAAATGTCAATATTAGAAAAAATGAAAAAATA
TTGCGACATTGATGGTATGT

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MFENGIKTKFESFFYNESKKAYFQKLMEKLDEEYEKYQVFPNKKALFRAIELTNFATLKIVIIGQDPYHKKGQADGLAFS
TRTKILPPSLRNLFLEIKNAYPNFSKENGNLENWAKQGVLLLNHVLTVRKSSPNSHKNIGWEVFSSNLINFIVKNKVDIV
FLLLGKKAKLAVKNINLEKQKVFAYSHPSPFSFAKSLKNSMVFRKINDFLKEKKRLEINWNL

Sequences:

>Translated_222_residues
MFENGIKTKFESFFYNESKKAYFQKLMEKLDEEYEKYQVFPNKKALFRAIELTNFATLKIVIIGQDPYHKKGQADGLAFS
TRTKILPPSLRNLFLEIKNAYPNFSKENGNLENWAKQGVLLLNHVLTVRKSSPNSHKNIGWEVFSSNLINFIVKNKVDIV
FLLLGKKAKLAVKNINLEKQKVFAYSHPSPFSFAKSLKNSMVFRKINDFLKEKKRLEINWNL
>Mature_222_residues
MFENGIKTKFESFFYNESKKAYFQKLMEKLDEEYEKYQVFPNKKALFRAIELTNFATLKIVIIGQDPYHKKGQADGLAFS
TRTKILPPSLRNLFLEIKNAYPNFSKENGNLENWAKQGVLLLNHVLTVRKSSPNSHKNIGWEVFSSNLINFIVKNKVDIV
FLLLGKKAKLAVKNINLEKQKVFAYSHPSPFSFAKSLKNSMVFRKINDFLKEKKRLEINWNL

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI6224979, Length=218, Percent_Identity=37.1559633027523, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI19718751, Length=218, Percent_Identity=37.1559633027523, Blast_Score=154, Evalue=4e-38,
Organism=Escherichia coli, GI1788934, Length=214, Percent_Identity=37.8504672897196, Blast_Score=163, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17556304, Length=208, Percent_Identity=39.9038461538462, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323620, Length=239, Percent_Identity=37.6569037656904, Blast_Score=144, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 25889; Mature: 25889

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENGIKTKFESFFYNESKKAYFQKLMEKLDEEYEKYQVFPNKKALFRAIELTNFATLKI
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEE
VIIGQDPYHKKGQADGLAFSTRTKILPPSLRNLFLEIKNAYPNFSKENGNLENWAKQGVL
EEECCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHH
LLNHVLTVRKSSPNSHKNIGWEVFSSNLINFIVKNKVDIVFLLLGKKAKLAVKNINLEKQ
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCHH
KVFAYSHPSPFSFAKSLKNSMVFRKINDFLKEKKRLEINWNL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC
>Mature Secondary Structure
MFENGIKTKFESFFYNESKKAYFQKLMEKLDEEYEKYQVFPNKKALFRAIELTNFATLKI
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEE
VIIGQDPYHKKGQADGLAFSTRTKILPPSLRNLFLEIKNAYPNFSKENGNLENWAKQGVL
EEECCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHH
LLNHVLTVRKSSPNSHKNIGWEVFSSNLINFIVKNKVDIVFLLLGKKAKLAVKNINLEKQ
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCHH
KVFAYSHPSPFSFAKSLKNSMVFRKINDFLKEKKRLEINWNL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA