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The map label for this gene is infC [H]

Identifier: 71893478

GI number: 71893478

Start: 158927

End: 159583

Strand: Reverse

Name: infC [H]

Synonym: MHJ_0121

Alternate gene names: 71893478

Gene position: 159583-158927 (Counterclockwise)

Preceding gene: 71893479

Following gene: 161611223

Centisome position: 17.78

GC content: 28.77

Gene sequence:

>657_bases
ATTTTGAATCACAGACCCCCTTTCCAGAAAAAACCATTACAAGACCACCAAATTAACGAAAATATACTTTTTCCCAACAT
TTTTTTAGTTGGAACTGATAATGAAAAAATTGGGAAAATCGCAACAAAAGAAGCAATTGAGTTAGCTAAATCCAAAGGTC
TTGATTTAGTTTTAATTTCGATTAAGGAAGTTAAAACTAAAGATAATCAAATTCAAAAAGTTCCAATTGCAAAAATTCTT
GACTATGGTAAATTTCGTTATGATATAAAAAAGAAAAAAAAAGAAGAAAAAGAAAAGCAATCTTTTACTAATAATCGTGA
AATTCGCGTTAGTTTTAATATAAATTTCCAGGATATATTAGTTAAATCGAAAAAAGCTCGTGAATTTATTCTTGATGGTG
ATCGTGTTAAAATTGCCCTTCGTTTCCGCGGTCGTGAAATTACTAGGGTTGATCAAGGCAGAAAAACACTTGATATCTTT
TATGATCAGTTAAAATATATTGCTAAAAAAAGTAAAGAAATTTCACAAAATGGAAACTTTTTAGTTATGCATCTTGAACG
TGATCGCAAAAAACTCCCAAAATTCATTTCAGCAAAACAACTAAAAGAATTACTCGAATACGAAAAACAAAAAAAAGAGG
AAGAAGAGAATGTCTAA

Upstream 100 bases:

>100_bases
AATTATTATTTTTTTGTCCAAAATTAAAATTAAATTCGTTTTTTAGTAAATTTTTTTAAAAAAAAATTTACTAAACGATC
TAAAATGGAGTAAAACTTAA

Downstream 100 bases:

>100_bases
AATCAAATTTAAAACAAAATCAGCATTAAAAAAAAGGATAAAAGTAACGGGAACAGGAAAAGTTAAACATGGCCATGCTT
ATCGTTCACATCTCGCTCAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MLNHRPPFQKKPLQDHQINENILFPNIFLVGTDNEKIGKIATKEAIELAKSKGLDLVLISIKEVKTKDNQIQKVPIAKIL
DYGKFRYDIKKKKKEEKEKQSFTNNREIRVSFNINFQDILVKSKKAREFILDGDRVKIALRFRGREITRVDQGRKTLDIF
YDQLKYIAKKSKEISQNGNFLVMHLERDRKKLPKFISAKQLKELLEYEKQKKEEEENV

Sequences:

>Translated_218_residues
MLNHRPPFQKKPLQDHQINENILFPNIFLVGTDNEKIGKIATKEAIELAKSKGLDLVLISIKEVKTKDNQIQKVPIAKIL
DYGKFRYDIKKKKKEEKEKQSFTNNREIRVSFNINFQDILVKSKKAREFILDGDRVKIALRFRGREITRVDQGRKTLDIF
YDQLKYIAKKSKEISQNGNFLVMHLERDRKKLPKFISAKQLKELLEYEKQKKEEEENV
>Mature_218_residues
MLNHRPPFQKKPLQDHQINENILFPNIFLVGTDNEKIGKIATKEAIELAKSKGLDLVLISIKEVKTKDNQIQKVPIAKIL
DYGKFRYDIKKKKKEEKEKQSFTNNREIRVSFNINFQDILVKSKKAREFILDGDRVKIALRFRGREITRVDQGRKTLDIF
YDQLKYIAKKSKEISQNGNFLVMHLERDRKKLPKFISAKQLKELLEYEKQKKEEEENV

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=153, Percent_Identity=34.640522875817, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 25801; Mature: 25801

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNHRPPFQKKPLQDHQINENILFPNIFLVGTDNEKIGKIATKEAIELAKSKGLDLVLIS
CCCCCCCCCCCCCCCCCCCCCEECCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEE
IKEVKTKDNQIQKVPIAKILDYGKFRYDIKKKKKEEKEKQSFTNNREIRVSFNINFQDIL
EEHHHCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHH
VKSKKAREFILDGDRVKIALRFRGREITRVDQGRKTLDIFYDQLKYIAKKSKEISQNGNF
HHHHHHHHHEECCCEEEEEEEECCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
LVMHLERDRKKLPKFISAKQLKELLEYEKQKKEEEENV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNHRPPFQKKPLQDHQINENILFPNIFLVGTDNEKIGKIATKEAIELAKSKGLDLVLIS
CCCCCCCCCCCCCCCCCCCCCEECCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEE
IKEVKTKDNQIQKVPIAKILDYGKFRYDIKKKKKEEKEKQSFTNNREIRVSFNINFQDIL
EEHHHCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHH
VKSKKAREFILDGDRVKIALRFRGREITRVDQGRKTLDIFYDQLKYIAKKSKEISQNGNF
HHHHHHHHHEECCCEEEEEEEECCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
LVMHLERDRKKLPKFISAKQLKELLEYEKQKKEEEENV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486291 [H]