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The map label for this gene is pgi

Identifier: 71892397

GI number: 71892397

Start: 787575

End: 789230

Strand: Reverse

Name: pgi

Synonym: BPEN_656

Alternate gene names: 71892397

Gene position: 789230-787575 (Counterclockwise)

Preceding gene: 71892398

Following gene: 71892395

Centisome position: 99.69

GC content: 31.04

Gene sequence:

>1656_bases
ATGAAAAATATAAATCCTAATCGTACACAAGCTTGGAAGCATCTCAAACAACATTTTGACGATATGAAGAGCACATCAAT
TAACGATTTGTTCAATCAAGACAAATATAGGTTTGCTCATTTCTCTAAAACATTTAATAATGAAATTTTAGTGGATTATT
CAAAAAACTTAATCACGAACGAAACTATTATTAAACTAATATCTTTGGCTATTGAATGTGATCTGATAGAAGCCATTTCA
GATATGTTTCATGGGGAAAAAATTAATTGTAGTGAAGATCGTGCTGTATTACACATAGCTTTAAGAAATATAAAAAATAC
GCCAATTTTAGTGGATGGATTCAACGTAATGCCACAAATAAATGCAGTACTAAATAAAATGAAACAATTTTGTAATCGGG
TTATTCAAGGTAATTGGACAGGTTACACGGATAAAATAATTACAGATATTGTTAATATAGGTATTGGCGGTTCCAATCTT
GGGCCTTATATGGTAACTGAAGCATTAAAGCCATATCGAAATCATTTAAATATGCATTTTGTCTCTAATATAGACGGCAC
ACACATTTTTGAGACATTAAAAAATTTAAATCCAGAAAATACACTATTTGTAATAGCATCAAAAACTTTTACTACGCAAG
AAACTATGACCAATGCGCTTAGTGCACGTAACTGGTTTTGTAAAGCTACTTCTGATGCACAACATATATCGAAGCATTTT
ATAGCATTATCCACAAATACCATAGCAGTGCGTAAATTTGGTATTGATCCATCAGAAAATATGTTTAAATTTTGGGATTG
GGTAGGCGGGCGTTATTCATTGTGGTCAGCAATTGGCTTACCGATAATGCTATCAGTAGGAGTGAGCAATTTTGAGTTAT
TGCTGACTGGAGCCCATGACATGGATATACATTTTTATAGCACACCGTTACATGAAAATCTACCAGTAATTCTAGCGCTT
ATTGGTATTTGGTACAATAATTTCTTTCAAGTTGAAACTGAAGCTATTTTTCCTTATGATCAATATATGCACCGTTTTAC
AGCATATTTACAGCAAGTAAATATGGAATCTAACGGAAAATGTGTAGATCGCAATGGATGCCCTATTACATATCAGACTG
GCCCTATTATATGGGGAGAACCTGGGACTAATGGACAACATTCATTTTATCAATTACTTCATCAAGGCACTAAAATGGTT
CCATGTGATTTTATTGCACCAGCAATTAGTCATAATCCTATATCTGATCATCATGAAAAATTAATATCAAATTTTTTTGC
TCAAACCAAAGCGTTGGCTTTTGGAAATACACATCTAACATCAATGCAAAAATATATACAATCTAAAAAAAATTACAAAC
ATGAACAATGTATAGTTCCTTTTAAGTTATGTAAAGGAAATAATCCTAGTAATTCTATTTTAGTTAAAAAAATTACTCCT
TATACTTTAGGAGCTTTGATTGCTTTATATGAACATAAAATATTTACACAAGGCATTATTTTTAATATTTATACTTTTGA
TCAATGGGGGGTAGAATTAGGAAAACAATTGGCTGACAGTATTTTACCAGAATTAAAATATGAAAGTATGATTTCTAAAA
ATCATGACAGTTCAACTTATGGTTTAATACATTGTTACAAATCCTGGTGTGGTTAA

Upstream 100 bases:

>100_bases
TTTATGTAGTAACCTGAATGAGTTATGGCGCGTTGAATAGTTTGTTTTAAATTTAATTTTTATTCACTTACTTTTGTGAT
AGAGCATAAGAAAATGAATT

Downstream 100 bases:

>100_bases
TGCAATTTTTTGATGTATAAAAAAGCTACATCAAATTGTGGTAGACGTGTGAAATAACATGTTTTGAGTAGTGTTTTTAT
TATATTCAAACATTCTATGA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MKNINPNRTQAWKHLKQHFDDMKSTSINDLFNQDKYRFAHFSKTFNNEILVDYSKNLITNETIIKLISLAIECDLIEAIS
DMFHGEKINCSEDRAVLHIALRNIKNTPILVDGFNVMPQINAVLNKMKQFCNRVIQGNWTGYTDKIITDIVNIGIGGSNL
GPYMVTEALKPYRNHLNMHFVSNIDGTHIFETLKNLNPENTLFVIASKTFTTQETMTNALSARNWFCKATSDAQHISKHF
IALSTNTIAVRKFGIDPSENMFKFWDWVGGRYSLWSAIGLPIMLSVGVSNFELLLTGAHDMDIHFYSTPLHENLPVILAL
IGIWYNNFFQVETEAIFPYDQYMHRFTAYLQQVNMESNGKCVDRNGCPITYQTGPIIWGEPGTNGQHSFYQLLHQGTKMV
PCDFIAPAISHNPISDHHEKLISNFFAQTKALAFGNTHLTSMQKYIQSKKNYKHEQCIVPFKLCKGNNPSNSILVKKITP
YTLGALIALYEHKIFTQGIIFNIYTFDQWGVELGKQLADSILPELKYESMISKNHDSSTYGLIHCYKSWCG

Sequences:

>Translated_551_residues
MKNINPNRTQAWKHLKQHFDDMKSTSINDLFNQDKYRFAHFSKTFNNEILVDYSKNLITNETIIKLISLAIECDLIEAIS
DMFHGEKINCSEDRAVLHIALRNIKNTPILVDGFNVMPQINAVLNKMKQFCNRVIQGNWTGYTDKIITDIVNIGIGGSNL
GPYMVTEALKPYRNHLNMHFVSNIDGTHIFETLKNLNPENTLFVIASKTFTTQETMTNALSARNWFCKATSDAQHISKHF
IALSTNTIAVRKFGIDPSENMFKFWDWVGGRYSLWSAIGLPIMLSVGVSNFELLLTGAHDMDIHFYSTPLHENLPVILAL
IGIWYNNFFQVETEAIFPYDQYMHRFTAYLQQVNMESNGKCVDRNGCPITYQTGPIIWGEPGTNGQHSFYQLLHQGTKMV
PCDFIAPAISHNPISDHHEKLISNFFAQTKALAFGNTHLTSMQKYIQSKKNYKHEQCIVPFKLCKGNNPSNSILVKKITP
YTLGALIALYEHKIFTQGIIFNIYTFDQWGVELGKQLADSILPELKYESMISKNHDSSTYGLIHCYKSWCG
>Mature_551_residues
MKNINPNRTQAWKHLKQHFDDMKSTSINDLFNQDKYRFAHFSKTFNNEILVDYSKNLITNETIIKLISLAIECDLIEAIS
DMFHGEKINCSEDRAVLHIALRNIKNTPILVDGFNVMPQINAVLNKMKQFCNRVIQGNWTGYTDKIITDIVNIGIGGSNL
GPYMVTEALKPYRNHLNMHFVSNIDGTHIFETLKNLNPENTLFVIASKTFTTQETMTNALSARNWFCKATSDAQHISKHF
IALSTNTIAVRKFGIDPSENMFKFWDWVGGRYSLWSAIGLPIMLSVGVSNFELLLTGAHDMDIHFYSTPLHENLPVILAL
IGIWYNNFFQVETEAIFPYDQYMHRFTAYLQQVNMESNGKCVDRNGCPITYQTGPIIWGEPGTNGQHSFYQLLHQGTKMV
PCDFIAPAISHNPISDHHEKLISNFFAQTKALAFGNTHLTSMQKYIQSKKNYKHEQCIVPFKLCKGNNPSNSILVKKITP
YTLGALIALYEHKIFTQGIIFNIYTFDQWGVELGKQLADSILPELKYESMISKNHDSSTYGLIHCYKSWCG

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

Organism=Homo sapiens, GI18201905, Length=547, Percent_Identity=57.4040219378428, Blast_Score=644, Evalue=0.0,
Organism=Homo sapiens, GI296080693, Length=547, Percent_Identity=53.9305301645338, Blast_Score=587, Evalue=1e-168,
Organism=Escherichia coli, GI1790457, Length=551, Percent_Identity=69.8729582577133, Blast_Score=820, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71996708, Length=552, Percent_Identity=54.8913043478261, Blast_Score=617, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI71996703, Length=540, Percent_Identity=55.9259259259259, Blast_Score=617, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6319673, Length=548, Percent_Identity=55.1094890510949, Blast_Score=589, Evalue=1e-169,
Organism=Drosophila melanogaster, GI24651916, Length=549, Percent_Identity=57.3770491803279, Blast_Score=629, Evalue=1e-180,
Organism=Drosophila melanogaster, GI24651914, Length=549, Percent_Identity=57.3770491803279, Blast_Score=629, Evalue=1e-180,
Organism=Drosophila melanogaster, GI17737445, Length=549, Percent_Identity=57.3770491803279, Blast_Score=629, Evalue=1e-180,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_BLOPB (Q491V0)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_278131.1
- ProteinModelPortal:   Q491V0
- SMR:   Q491V0
- STRING:   Q491V0
- GeneID:   3562733
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_656
- eggNOG:   COG0166
- HOGENOM:   HBG352954
- OMA:   GPKIVSQ
- ProtClustDB:   PRK00179
- BioCyc:   CBLO291272:BPEN_656-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189
- Gene3D:   G3DSA:1.10.1390.10
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 62901; Mature: 62901

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 356-356 ACT_SITE 387-387 ACT_SITE 515-515

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNINPNRTQAWKHLKQHFDDMKSTSINDLFNQDKYRFAHFSKTFNNEILVDYSKNLITN
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCH
ETIIKLISLAIECDLIEAISDMFHGEKINCSEDRAVLHIALRNIKNTPILVDGFNVMPQI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCHHH
NAVLNKMKQFCNRVIQGNWTGYTDKIITDIVNIGIGGSNLGPYMVTEALKPYRNHLNMHF
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEE
VSNIDGTHIFETLKNLNPENTLFVIASKTFTTQETMTNALSARNWFCKATSDAQHISKHF
ECCCCHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHE
IALSTNTIAVRKFGIDPSENMFKFWDWVGGRYSLWSAIGLPIMLSVGVSNFELLLTGAHD
EEEECCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHCCCEEEECCCCCEEEEEECCCC
MDIHFYSTPLHENLPVILALIGIWYNNFFQVETEAIFPYDQYMHRFTAYLQQVNMESNGK
CEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCC
CVDRNGCPITYQTGPIIWGEPGTNGQHSFYQLLHQGTKMVPCDFIAPAISHNPISDHHEK
EECCCCCEEEECCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHH
LISNFFAQTKALAFGNTHLTSMQKYIQSKKNYKHEQCIVPFKLCKGNNPSNSILVKKITP
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCEEEEECCC
YTLGALIALYEHKIFTQGIIFNIYTFDQWGVELGKQLADSILPELKYESMISKNHDSSTY
HHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GLIHCYKSWCG
HHHHHHHHHCC
>Mature Secondary Structure
MKNINPNRTQAWKHLKQHFDDMKSTSINDLFNQDKYRFAHFSKTFNNEILVDYSKNLITN
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCH
ETIIKLISLAIECDLIEAISDMFHGEKINCSEDRAVLHIALRNIKNTPILVDGFNVMPQI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCHHH
NAVLNKMKQFCNRVIQGNWTGYTDKIITDIVNIGIGGSNLGPYMVTEALKPYRNHLNMHF
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEE
VSNIDGTHIFETLKNLNPENTLFVIASKTFTTQETMTNALSARNWFCKATSDAQHISKHF
ECCCCHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHE
IALSTNTIAVRKFGIDPSENMFKFWDWVGGRYSLWSAIGLPIMLSVGVSNFELLLTGAHD
EEEECCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHCCCEEEECCCCCEEEEEECCCC
MDIHFYSTPLHENLPVILALIGIWYNNFFQVETEAIFPYDQYMHRFTAYLQQVNMESNGK
CEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCC
CVDRNGCPITYQTGPIIWGEPGTNGQHSFYQLLHQGTKMVPCDFIAPAISHNPISDHHEK
EECCCCCEEEECCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHH
LISNFFAQTKALAFGNTHLTSMQKYIQSKKNYKHEQCIVPFKLCKGNNPSNSILVKKITP
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCEEEEECCC
YTLGALIALYEHKIFTQGIIFNIYTFDQWGVELGKQLADSILPELKYESMISKNHDSSTY
HHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GLIHCYKSWCG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA