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The map label for this gene is ureC

Identifier: 71892295

GI number: 71892295

Start: 647273

End: 648976

Strand: Reverse

Name: ureC

Synonym: BPEN_542

Alternate gene names: 71892295

Gene position: 648976-647273 (Counterclockwise)

Preceding gene: 71892296

Following gene: 71892294

Centisome position: 81.98

GC content: 37.09

Gene sequence:

>1704_bases
ATGTTACTATCCAAGCATGATTATGCTTCTTTATTTGGACCAACTATTGGTGATTCTGTACGATTAGCAGATACTGAATT
GTGGATAAGAATAGAAAAAGATTTTACTGTGTATGGGGAAGAAGTAAAATTTGGGGGAGGTAAAGTTATACGAGATGGTA
TGGGTCAAGGACAAATGAGTAGTAAAGATTGTGTTGATTTAGTATTGACTAATGCAGTAATTCTTGATTACTGGGGAATA
ATAAAAGCAGATATTGGTATTAATAATGGTCGTATATCAGGTATTGGAAAAGCAGGAAATCCGGATGTACAGCCAAATGT
GACGATATCTATTGGCCCTGGAACAGAGATAATAGCAGCGGAAGGTAAAATTGTTACAGCTGGAGGAATTGACGCTCATG
TTCATTTTATTTGTCCTCAGCAAGTAGAAGAAGCATTGTGTTCCGGAATTACTACATTTATTGGAGGCGGTACTGGGCCG
GCAACAGGAAGTAATGCAACTACCTGTACTCCAGGGCCTTGGTTTATATCTCGTATGCTACAAGTAGCAGATACCTTGCC
TATTAATATTGGGGTTACCGGTAAAGGTAGTGCTTCTTTCCCTGATGCTTTAGAAGAGCAAATAATTGCAGGGGCGATTG
GTTTAAAGGTGCATGAAGATTGGGGTGCAACACCAGCTGCTATCGATTGTTGTTTAAATGTGGCTGATCGTTTTGATATT
CAGGTTTCTATGCATACTGATACTTTAAATGAATCAGGATTTGTTGAGGATACCTTATCTGCTATCAAAGGTAGAACAGT
GCATGCTTATCATACTGAGGGTGCAGGTGGAGGACATTCTCCAGATATTATACGTATGTGTGGATTTTCTAATGTGTTAC
CATCATCTACCAATCCTACTATGCCTTATACTGTTAATACAATAGATGAACATTTAGATATGATGATGATTTGTCATAAT
CTTAATCCTAATCTTCCTGAAGATATGGCATTTTCAGAGTCTAGAATTAGGAGGGAGACAATTGCAGCTGAAGATGTATT
ACATGATCTTGGAGCTTTATCTATGATTTCTTCTGATTCTCAAGCTATGGGACGAGTCGGAGAAGTGATTTTACGTACTT
GGCAGACAGCACATAAGATGAAACAACAGAGAGGTTCATTATTAGGTGATGCTACTAGATATGATGATAATGTTCGCGTA
AAACGGTACATTGCTAAATATACAATTAACCCAGCGATAACTCACGGAATTTCTCATGAAGTTGGTTCTGTTGAAATAGG
AAAATTGGCAGATTTAGTACTATGGTCTCCTGTTTTTTTTGGAGTTAAACCAGAGTTAATAATTAAAGGCGGTATGATTA
TCTCTTCTGTTATGGGAGATCCTAATGCTTCTATACCTACTCCTCAACCAGTACATTATCGGTTAATGTTCGGAGCACGT
GGTAAAGCAAAACATGCTACACGTATGACTTTTCTATCTCAAGTTGCTTATAATTCAGAATTAACAGATTATTTAAAGTT
GGTTAGTTTGATTGGTGAGGTGCGTCATTGCAGAAATATTCAAAAGAAGCATATGATTAATAATTCTTGGCAACCAGTTA
TTGAAGTAGATTCTCAAACTTACCAAGTACGTGCTAATGGAGAATTATTAACTTGCGAGCCTGCATCTGTATTACCAATG
TCACAACGTTATTTTCTTTTTTAA

Upstream 100 bases:

>100_bases
TTGAACCAGGACAGTTTAGGACCGTAGAACTTGTAAAATATGCAGGTGCATGTAAAATTTATGGGTTTTGTAAAGCCATT
ATGGGAAAGTTAGATTAGTT

Downstream 100 bases:

>100_bases
CGTGAAATATAATCACATGTGATATATATAAAGTGGATATTGTTTTTTTATTAAATGTTTTGAATAATTGTTTTTTGGTA
TGAGTGGGGGGGTAATAACA

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MLLSKHDYASLFGPTIGDSVRLADTELWIRIEKDFTVYGEEVKFGGGKVIRDGMGQGQMSSKDCVDLVLTNAVILDYWGI
IKADIGINNGRISGIGKAGNPDVQPNVTISIGPGTEIIAAEGKIVTAGGIDAHVHFICPQQVEEALCSGITTFIGGGTGP
ATGSNATTCTPGPWFISRMLQVADTLPINIGVTGKGSASFPDALEEQIIAGAIGLKVHEDWGATPAAIDCCLNVADRFDI
QVSMHTDTLNESGFVEDTLSAIKGRTVHAYHTEGAGGGHSPDIIRMCGFSNVLPSSTNPTMPYTVNTIDEHLDMMMICHN
LNPNLPEDMAFSESRIRRETIAAEDVLHDLGALSMISSDSQAMGRVGEVILRTWQTAHKMKQQRGSLLGDATRYDDNVRV
KRYIAKYTINPAITHGISHEVGSVEIGKLADLVLWSPVFFGVKPELIIKGGMIISSVMGDPNASIPTPQPVHYRLMFGAR
GKAKHATRMTFLSQVAYNSELTDYLKLVSLIGEVRHCRNIQKKHMINNSWQPVIEVDSQTYQVRANGELLTCEPASVLPM
SQRYFLF

Sequences:

>Translated_567_residues
MLLSKHDYASLFGPTIGDSVRLADTELWIRIEKDFTVYGEEVKFGGGKVIRDGMGQGQMSSKDCVDLVLTNAVILDYWGI
IKADIGINNGRISGIGKAGNPDVQPNVTISIGPGTEIIAAEGKIVTAGGIDAHVHFICPQQVEEALCSGITTFIGGGTGP
ATGSNATTCTPGPWFISRMLQVADTLPINIGVTGKGSASFPDALEEQIIAGAIGLKVHEDWGATPAAIDCCLNVADRFDI
QVSMHTDTLNESGFVEDTLSAIKGRTVHAYHTEGAGGGHSPDIIRMCGFSNVLPSSTNPTMPYTVNTIDEHLDMMMICHN
LNPNLPEDMAFSESRIRRETIAAEDVLHDLGALSMISSDSQAMGRVGEVILRTWQTAHKMKQQRGSLLGDATRYDDNVRV
KRYIAKYTINPAITHGISHEVGSVEIGKLADLVLWSPVFFGVKPELIIKGGMIISSVMGDPNASIPTPQPVHYRLMFGAR
GKAKHATRMTFLSQVAYNSELTDYLKLVSLIGEVRHCRNIQKKHMINNSWQPVIEVDSQTYQVRANGELLTCEPASVLPM
SQRYFLF
>Mature_567_residues
MLLSKHDYASLFGPTIGDSVRLADTELWIRIEKDFTVYGEEVKFGGGKVIRDGMGQGQMSSKDCVDLVLTNAVILDYWGI
IKADIGINNGRISGIGKAGNPDVQPNVTISIGPGTEIIAAEGKIVTAGGIDAHVHFICPQQVEEALCSGITTFIGGGTGP
ATGSNATTCTPGPWFISRMLQVADTLPINIGVTGKGSASFPDALEEQIIAGAIGLKVHEDWGATPAAIDCCLNVADRFDI
QVSMHTDTLNESGFVEDTLSAIKGRTVHAYHTEGAGGGHSPDIIRMCGFSNVLPSSTNPTMPYTVNTIDEHLDMMMICHN
LNPNLPEDMAFSESRIRRETIAAEDVLHDLGALSMISSDSQAMGRVGEVILRTWQTAHKMKQQRGSLLGDATRYDDNVRV
KRYIAKYTINPAITHGISHEVGSVEIGKLADLVLWSPVFFGVKPELIIKGGMIISSVMGDPNASIPTPQPVHYRLMFGAR
GKAKHATRMTFLSQVAYNSELTDYLKLVSLIGEVRHCRNIQKKHMINNSWQPVIEVDSQTYQVRANGELLTCEPASVLPM
SQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_BLOPB (Q492E9)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_278029.1
- ProteinModelPortal:   Q492E9
- SMR:   Q492E9
- STRING:   Q492E9
- GeneID:   3562879
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_542
- eggNOG:   COG0804
- HOGENOM:   HBG357507
- OMA:   TIHAFHT
- ProtClustDB:   PRK13207
- BioCyc:   CBLO291272:BPEN_542-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 61470; Mature: 61470

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 319-319 BINDING 218-218

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSKHDYASLFGPTIGDSVRLADTELWIRIEKDFTVYGEEVKFGGGKVIRDGMGQGQMS
CCCCCCCHHHHCCCCCCCCEEEECEEEEEEEECCEEEECCEEEECCCEEEECCCCCCCCC
SKDCVDLVLTNAVILDYWGIIKADIGINNGRISGIGKAGNPDVQPNVTISIGPGTEIIAA
CHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEECCCCCCCCCCCCEEEEECCCCEEEEE
EGKIVTAGGIDAHVHFICPQQVEEALCSGITTFIGGGTGPATGSNATTCTPGPWFISRML
CCEEEEECCCCEEEEEECHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
QVADTLPINIGVTGKGSASFPDALEEQIIAGAIGLKVHEDWGATPAAIDCCLNVADRFDI
HHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCEEE
QVSMHTDTLNESGFVEDTLSAIKGRTVHAYHTEGAGGGHSPDIIRMCGFSNVLPSSTNPT
EEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCC
MPYTVNTIDEHLDMMMICHNLNPNLPEDMAFSESRIRRETIAAEDVLHDLGALSMISSDS
CCEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QAMGRVGEVILRTWQTAHKMKQQRGSLLGDATRYDDNVRVKRYIAKYTINPAITHGISHE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEHHHEECCHHHHCCCCCC
VGSVEIGKLADLVLWSPVFFGVKPELIIKGGMIISSVMGDPNASIPTPQPVHYRLMFGAR
CCCEEHHHHHHHHHHHHHHHCCCCCEEEECCEEEEHHCCCCCCCCCCCCCEEEEEEECCC
GKAKHATRMTFLSQVAYNSELTDYLKLVSLIGEVRHCRNIQKKHMINNSWQPVIEVDSQT
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCE
YQVRANGELLTCEPASVLPMSQRYFLF
EEEEECCCEEEECCCCCCCCCCCEECC
>Mature Secondary Structure
MLLSKHDYASLFGPTIGDSVRLADTELWIRIEKDFTVYGEEVKFGGGKVIRDGMGQGQMS
CCCCCCCHHHHCCCCCCCCEEEECEEEEEEEECCEEEECCEEEECCCEEEECCCCCCCCC
SKDCVDLVLTNAVILDYWGIIKADIGINNGRISGIGKAGNPDVQPNVTISIGPGTEIIAA
CHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEECCCCCCCCCCCCEEEEECCCCEEEEE
EGKIVTAGGIDAHVHFICPQQVEEALCSGITTFIGGGTGPATGSNATTCTPGPWFISRML
CCEEEEECCCCEEEEEECHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
QVADTLPINIGVTGKGSASFPDALEEQIIAGAIGLKVHEDWGATPAAIDCCLNVADRFDI
HHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCEEE
QVSMHTDTLNESGFVEDTLSAIKGRTVHAYHTEGAGGGHSPDIIRMCGFSNVLPSSTNPT
EEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCC
MPYTVNTIDEHLDMMMICHNLNPNLPEDMAFSESRIRRETIAAEDVLHDLGALSMISSDS
CCEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QAMGRVGEVILRTWQTAHKMKQQRGSLLGDATRYDDNVRVKRYIAKYTINPAITHGISHE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEHHHEECCHHHHCCCCCC
VGSVEIGKLADLVLWSPVFFGVKPELIIKGGMIISSVMGDPNASIPTPQPVHYRLMFGAR
CCCEEHHHHHHHHHHHHHHHCCCCCEEEECCEEEEHHCCCCCCCCCCCCCEEEEEEECCC
GKAKHATRMTFLSQVAYNSELTDYLKLVSLIGEVRHCRNIQKKHMINNSWQPVIEVDSQT
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCE
YQVRANGELLTCEPASVLPMSQRYFLF
EEEEECCCEEEECCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA