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The map label for this gene is tdk

Identifier: 71892209

GI number: 71892209

Start: 529960

End: 530577

Strand: Reverse

Name: tdk

Synonym: BPEN_447

Alternate gene names: 71892209

Gene position: 530577-529960 (Counterclockwise)

Preceding gene: 71892218

Following gene: 71892207

Centisome position: 67.02

GC content: 29.45

Gene sequence:

>618_bases
ATGGCACAATTATATTTTTATTATTCCGCAATGAATGCTGGAAAAACTACCGCATTATTACAGTCTTCTTATAATTATCA
AGAAAGAGGAATGCGCACTGTGTTATATACTGCTGACATGAATTCTAGAGATAATAGATATAAACAAATTAAATCTCGTA
TTGGATTATATGCTTCTGCTAGAGTATTTAACATTAAAACTAATTTTTTTGATCAAGTAGTAACTATACATCAAAAGGAT
ATAATACATTGTGTGTTAGTGGATGAGTGTCATTTTCTCAACCGTAATCAAGTGATTGATTTAAGCAAAATAGTCGATGT
GTTAAATATTCCAGTATTATGTTATGGATTACGTACTGATTTTAGAGCTGATTTATTTTCAGGTAGTCTATGGTTATTAG
CATGGGCAGATAAATTAATCGAATTAAAAACTATTTGTTATTGTGGACGAAAGGCTAATAGAGTTCTTAGAATTGATGAT
CAAGGTTTAATAATTCGAGATGGAAATCAAATATTGGTTGGTGGTAATAATCGTTATGTTTCAGTGTGCCGCAAACATTT
TGTAGAACAATTAGAGTCACCATTATCTTTAACAAAACGTGTATATAAAAATAGATAA

Upstream 100 bases:

>100_bases
TATGGATTAAATAATTTTTAAACCTAATATTATCTATAATTTAAATTATATTTATGTTGCTAATAGTAAAATACTGTGAG
TCGAATAGGGTGTTAATTGT

Downstream 100 bases:

>100_bases
TAGTTTATTGAAGTTATGCATATGTTACTTTCTTTTAAATAAGATATATTTTTATGCACAATAAATTTTATATTCAAGTT
ATAAACTGATATGGATATTA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MAQLYFYYSAMNAGKTTALLQSSYNYQERGMRTVLYTADMNSRDNRYKQIKSRIGLYASARVFNIKTNFFDQVVTIHQKD
IIHCVLVDECHFLNRNQVIDLSKIVDVLNIPVLCYGLRTDFRADLFSGSLWLLAWADKLIELKTICYCGRKANRVLRIDD
QGLIIRDGNQILVGGNNRYVSVCRKHFVEQLESPLSLTKRVYKNR

Sequences:

>Translated_205_residues
MAQLYFYYSAMNAGKTTALLQSSYNYQERGMRTVLYTADMNSRDNRYKQIKSRIGLYASARVFNIKTNFFDQVVTIHQKD
IIHCVLVDECHFLNRNQVIDLSKIVDVLNIPVLCYGLRTDFRADLFSGSLWLLAWADKLIELKTICYCGRKANRVLRIDD
QGLIIRDGNQILVGGNNRYVSVCRKHFVEQLESPLSLTKRVYKNR
>Mature_204_residues
AQLYFYYSAMNAGKTTALLQSSYNYQERGMRTVLYTADMNSRDNRYKQIKSRIGLYASARVFNIKTNFFDQVVTIHQKDI
IHCVLVDECHFLNRNQVIDLSKIVDVLNIPVLCYGLRTDFRADLFSGSLWLLAWADKLIELKTICYCGRKANRVLRIDDQ
GLIIRDGNQILVGGNNRYVSVCRKHFVEQLESPLSLTKRVYKNR

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family

Homologues:

Organism=Escherichia coli, GI1787490, Length=192, Percent_Identity=64.5833333333333, Blast_Score=269, Evalue=8e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KITH_BLOPB (Q492N1)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277942.1
- ProteinModelPortal:   Q492N1
- SMR:   Q492N1
- STRING:   Q492N1
- GeneID:   3562656
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_447
- eggNOG:   COG1435
- HOGENOM:   HBG522108
- OMA:   FRYGAMN
- ProtClustDB:   PRK04296
- BioCyc:   CBLO291272:BPEN_447-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00124
- InterPro:   IPR001267
- InterPro:   IPR020634
- PANTHER:   PTHR11441
- PIRSF:   PIRSF035805

Pfam domain/function: PF00265 TK

EC number: =2.7.1.21

Molecular weight: Translated: 23820; Mature: 23689

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: ACT_SITE 89-89

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLYFYYSAMNAGKTTALLQSSYNYQERGMRTVLYTADMNSRDNRYKQIKSRIGLYASA
CCEEEEEEEECCCCCHHHHHHCCCCHHHCCCEEEEEEECCCCCHHHHHHHHHHHCEEEEE
RVFNIKTNFFDQVVTIHQKDIIHCVLVDECHFLNRNQVIDLSKIVDVLNIPVLCYGLRTD
EEEEEEHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECHHHHHHHHCCCEEEEECCCC
FRADLFSGSLWLLAWADKLIELKTICYCGRKANRVLRIDDQGLIIRDGNQILVGGNNRYV
CHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCEEEECCCCCHH
SVCRKHFVEQLESPLSLTKRVYKNR
HHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
AQLYFYYSAMNAGKTTALLQSSYNYQERGMRTVLYTADMNSRDNRYKQIKSRIGLYASA
CEEEEEEEECCCCCHHHHHHCCCCHHHCCCEEEEEEECCCCCHHHHHHHHHHHCEEEEE
RVFNIKTNFFDQVVTIHQKDIIHCVLVDECHFLNRNQVIDLSKIVDVLNIPVLCYGLRTD
EEEEEEHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECHHHHHHHHCCCEEEEECCCC
FRADLFSGSLWLLAWADKLIELKTICYCGRKANRVLRIDDQGLIIRDGNQILVGGNNRYV
CHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCEEEECCCCCHH
SVCRKHFVEQLESPLSLTKRVYKNR
HHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA