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The map label for this gene is fabA

Identifier: 71892194

GI number: 71892194

Start: 507833

End: 508351

Strand: Direct

Name: fabA

Synonym: BPEN_432

Alternate gene names: 71892194

Gene position: 507833-508351 (Clockwise)

Preceding gene: 71892193

Following gene: 71892195

Centisome position: 64.15

GC content: 32.95

Gene sequence:

>519_bases
ATGCTTAATAAACGTGAATACTATACAAAAGAAGATTTATTAGCTTCCAGCAGGGGTGAATTATTTGGAAAAAACGGACC
TACACTACCCGCTCCTAACATGCTGATGATGGATCGAGTAATAAAAATGACTAAAAATGGAGGAAATTATAATAAAGGAT
TTATAGAAGCAGAATTAGATATTCAATCAGATATGTGGTTTTTTAATTGTCATTTTATAAAAGATCCGGTTATGCCGGGA
TGTTTAGGATTGGATGCTATGTGGCAATTAGTAGGATTTTACCTCGGTTGGCTCGGAGGAGAAGGTAAAGGACGCGCTTT
AGGAGTAAAAGAGGTTAAATTTACTGGCCAAATCTTACCTACATCTAAAAAAGTTACTTATTTTATTCATTTTCGAAGAA
TCATCAACAGAAAACTAATTATGGGAATGGCTGATGGTGAAGTATCATGTGATGGAAAAATAATTTATACTGCAACTGAT
TTAAAAGTTGGATTATTTAAGAATTCTACAGTATTCTAA

Upstream 100 bases:

>100_bases
CATCATATACATATACACACGCGGAATATAATCAGATTTAACAATTTGATATTTTATATTGTACGAAATGAGCAAATATA
TTCATAAGATGAGATGTACT

Downstream 100 bases:

>100_bases
AATATTTAGATATAAAATATAAAAATATTTTTACGTATTAATGTACCTCTATTAACTAACTCCATCAAAATTTAACTTAT
TTCATATAAAAGACGCAACT

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MLNKREYYTKEDLLASSRGELFGKNGPTLPAPNMLMMDRVIKMTKNGGNYNKGFIEAELDIQSDMWFFNCHFIKDPVMPG
CLGLDAMWQLVGFYLGWLGGEGKGRALGVKEVKFTGQILPTSKKVTYFIHFRRIINRKLIMGMADGEVSCDGKIIYTATD
LKVGLFKNSTVF

Sequences:

>Translated_172_residues
MLNKREYYTKEDLLASSRGELFGKNGPTLPAPNMLMMDRVIKMTKNGGNYNKGFIEAELDIQSDMWFFNCHFIKDPVMPG
CLGLDAMWQLVGFYLGWLGGEGKGRALGVKEVKFTGQILPTSKKVTYFIHFRRIINRKLIMGMADGEVSCDGKIIYTATD
LKVGLFKNSTVF
>Mature_172_residues
MLNKREYYTKEDLLASSRGELFGKNGPTLPAPNMLMMDRVIKMTKNGGNYNKGFIEAELDIQSDMWFFNCHFIKDPVMPG
CLGLDAMWQLVGFYLGWLGGEGKGRALGVKEVKFTGQILPTSKKVTYFIHFRRIINRKLIMGMADGEVSCDGKIIYTATD
LKVGLFKNSTVF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily

Homologues:

Organism=Escherichia coli, GI1787187, Length=172, Percent_Identity=78.4883720930232, Blast_Score=297, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABA_BLOPB (Q492P4)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277927.1
- ProteinModelPortal:   Q492P4
- SMR:   Q492P4
- STRING:   Q492P4
- GeneID:   3562742
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_432
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   CHFKGDP
- ProtClustDB:   PRK05174
- BioCyc:   CBLO291272:BPEN_432-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00405
- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114
- PANTHER:   PTHR11712
- TIGRFAMs:   TIGR01749

Pfam domain/function: PF07977 FabA

EC number: =4.2.1.60

Molecular weight: Translated: 19409; Mature: 19409

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: ACT_SITE 71-71

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKREYYTKEDLLASSRGELFGKNGPTLPAPNMLMMDRVIKMTKNGGNYNKGFIEAELD
CCCCCCCCCHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEE
IQSDMWFFNCHFIKDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVKEVKFTGQILP
ECCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECEEEEEEECEECC
TSKKVTYFIHFRRIINRKLIMGMADGEVSCDGKIIYTATDLKVGLFKNSTVF
CCCCEEEEEHHHHHHCHHEEEEECCCCEECCCEEEEEECCEEEEEECCCCCC
>Mature Secondary Structure
MLNKREYYTKEDLLASSRGELFGKNGPTLPAPNMLMMDRVIKMTKNGGNYNKGFIEAELD
CCCCCCCCCHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEE
IQSDMWFFNCHFIKDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVKEVKFTGQILP
ECCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECEEEEEEECEECC
TSKKVTYFIHFRRIINRKLIMGMADGEVSCDGKIIYTATDLKVGLFKNSTVF
CCCCEEEEEHHHHHHCHHEEEEECCCCEECCCEEEEEECCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA