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The map label for this gene is serC

Identifier: 71892161

GI number: 71892161

Start: 463815

End: 464903

Strand: Reverse

Name: serC

Synonym: BPEN_394

Alternate gene names: 71892161

Gene position: 464903-463815 (Counterclockwise)

Preceding gene: 71892162

Following gene: 71892160

Centisome position: 58.73

GC content: 31.04

Gene sequence:

>1089_bases
ATGAATGAAGTATTCAATTTTAGCGCGGGTCCAGCAATGTTGCCGAAACAAGTTTTAAGGCAAGTTAAAGAAGAATTATA
TAGTTGGAATAATATGGGCGTCTCCGTCATAGAGATAAGTCATCGTAGTAAAGAATTTTTGCAATTAATGCAAGAAGCGA
AACAAGACATGCGTGATCTTCTTGATATTACAGAAAATTATGAAGTTTTATTTTGTCATGGTGGAGCGCGTGCACAATTT
TCTGCGATTCCTATGAATTTATTAAAAACATCTTCAGAAAGAGTTGATTATATAATAACTGGGTATTGGGCATACAACGC
AGCAATAGAAGCAAAAAAATATTGTGATCCACGTATAATTAATGTGGTCGGCGAAAAAAATGGACTACATAATATTCAAC
CTATATCTAAATGGGATGTTTCTGAAAATAGTCTGTATATTCATTATTGTCCTAATGAAACTATTGATGGAATCGCTGTA
TATGAAACTCCAAATTTTTCTGATAAAATAGTGGTAGCGGATTGTTCTTCAACTTTATTTTCGGGCCCACTGAATATAAA
CCGTTTTGGTATAATTTATGCTACGGCTCAAAAAAACATTGGCATATCTGGTTTGACTGTGATAATTATCAGAAAAGATT
TATTGAAAGAACCTTGTCTAGTAGTCCCGTCTATTTTAAATTATAAAATTTTAGCTGATAATTTCTCAATGTTTAATACG
CCTGTCACTATGTCCTGGTACGTTGCTAGTTTAATTTTTAAATGGTTGAAAAAACAAGGAGGCTTAAAGGAAATTAATAA
ACGTAATCAAGAAAAATCAGCTCTTTTATATGACGCTATTGATTCTAGTAATTTCTATTATAACAATATTAGTCTATCTA
ATCGTTCATACATGAACATCCCCTTTTTTTTAAAAAACAGTAAATTAAATGATCTTTTTTTAAAAGAATCAATATCTTTC
GGATTGCATGGTTTGAAAGGACATAAAGTAGTGGGGGGTATGCGCGCATCTTTATATAATGCCATGACATTAGAAGGTGT
AAAAAAATTAATTAGATTTATGAAATTATTTTCTGAAAAATATCGCTAA

Upstream 100 bases:

>100_bases
TACTTAAAATGATTTTATATTTTTAATTGTTGTTTTCAATAATAGTTCATTATGAAGGATACTGTTTTAATTAATTTAAT
TATTTATGATCGATCATTAT

Downstream 100 bases:

>100_bases
TTATATTCAATCGATTACATATGTTCATATGTTAAATAGTTAAATACAATCACATATTTTTATTGTAAATGGTATATTAT
GGGCTATTAATTTCAAAAAT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MNEVFNFSAGPAMLPKQVLRQVKEELYSWNNMGVSVIEISHRSKEFLQLMQEAKQDMRDLLDITENYEVLFCHGGARAQF
SAIPMNLLKTSSERVDYIITGYWAYNAAIEAKKYCDPRIINVVGEKNGLHNIQPISKWDVSENSLYIHYCPNETIDGIAV
YETPNFSDKIVVADCSSTLFSGPLNINRFGIIYATAQKNIGISGLTVIIIRKDLLKEPCLVVPSILNYKILADNFSMFNT
PVTMSWYVASLIFKWLKKQGGLKEINKRNQEKSALLYDAIDSSNFYYNNISLSNRSYMNIPFFLKNSKLNDLFLKESISF
GLHGLKGHKVVGGMRASLYNAMTLEGVKKLIRFMKLFSEKYR

Sequences:

>Translated_362_residues
MNEVFNFSAGPAMLPKQVLRQVKEELYSWNNMGVSVIEISHRSKEFLQLMQEAKQDMRDLLDITENYEVLFCHGGARAQF
SAIPMNLLKTSSERVDYIITGYWAYNAAIEAKKYCDPRIINVVGEKNGLHNIQPISKWDVSENSLYIHYCPNETIDGIAV
YETPNFSDKIVVADCSSTLFSGPLNINRFGIIYATAQKNIGISGLTVIIIRKDLLKEPCLVVPSILNYKILADNFSMFNT
PVTMSWYVASLIFKWLKKQGGLKEINKRNQEKSALLYDAIDSSNFYYNNISLSNRSYMNIPFFLKNSKLNDLFLKESISF
GLHGLKGHKVVGGMRASLYNAMTLEGVKKLIRFMKLFSEKYR
>Mature_362_residues
MNEVFNFSAGPAMLPKQVLRQVKEELYSWNNMGVSVIEISHRSKEFLQLMQEAKQDMRDLLDITENYEVLFCHGGARAQF
SAIPMNLLKTSSERVDYIITGYWAYNAAIEAKKYCDPRIINVVGEKNGLHNIQPISKWDVSENSLYIHYCPNETIDGIAV
YETPNFSDKIVVADCSSTLFSGPLNINRFGIIYATAQKNIGISGLTVIIIRKDLLKEPCLVVPSILNYKILADNFSMFNT
PVTMSWYVASLIFKWLKKQGGLKEINKRNQEKSALLYDAIDSSNFYYNNISLSNRSYMNIPFFLKNSKLNDLFLKESISF
GLHGLKGHKVVGGMRASLYNAMTLEGVKKLIRFMKLFSEKYR

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily

Homologues:

Organism=Homo sapiens, GI17402893, Length=367, Percent_Identity=41.6893732970027, Blast_Score=301, Evalue=6e-82,
Organism=Homo sapiens, GI10863955, Length=362, Percent_Identity=37.292817679558, Blast_Score=256, Evalue=3e-68,
Organism=Escherichia coli, GI1787136, Length=362, Percent_Identity=55.2486187845304, Blast_Score=451, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17506897, Length=360, Percent_Identity=41.9444444444444, Blast_Score=286, Evalue=8e-78,
Organism=Saccharomyces cerevisiae, GI6324758, Length=387, Percent_Identity=35.1421188630491, Blast_Score=232, Evalue=6e-62,
Organism=Drosophila melanogaster, GI21356589, Length=361, Percent_Identity=41.2742382271468, Blast_Score=287, Evalue=1e-77,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SERC_BLOPB (Q492S5)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277893.1
- HSSP:   Q59196
- ProteinModelPortal:   Q492S5
- SMR:   Q492S5
- STRING:   Q492S5
- GeneID:   3562759
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_394
- eggNOG:   COG1932
- HOGENOM:   HBG289982
- OMA:   TFAWYLA
- ProtClustDB:   PRK05355
- BioCyc:   CBLO291272:BPEN_394-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00160
- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000525
- TIGRFAMs:   TIGR01364

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.52

Molecular weight: Translated: 41296; Mature: 41296

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: BINDING 42-42 BINDING 103-103 BINDING 154-154 BINDING 174-174 BINDING 197-197

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVFNFSAGPAMLPKQVLRQVKEELYSWNNMGVSVIEISHRSKEFLQLMQEAKQDMRDL
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LDITENYEVLFCHGGARAQFSAIPMNLLKTSSERVDYIITGYWAYNAAIEAKKYCDPRII
HHHCCCCEEEEEECCCCCEEHHCCHHHHHCCCCCCCEEEEEEEEECEEECHHHCCCCEEE
NVVGEKNGLHNIQPISKWDVSENSLYIHYCPNETIDGIAVYETPNFSDKIVVADCSSTLF
EEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCEEEEECCCHHH
SGPLNINRFGIIYATAQKNIGISGLTVIIIRKDLLKEPCLVVPSILNYKILADNFSMFNT
CCCCCCCEEEEEEEEECCCCCCCCEEEEEEEHHHHCCCCHHHHHHHCEEEEECCCCCCCC
PVTMSWYVASLIFKWLKKQGGLKEINKRNQEKSALLYDAIDSSNFYYNNISLSNRSYMNI
CEEHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHEEEEEEECCCCEEEEEEEECCCCEEEC
PFFLKNSKLNDLFLKESISFGLHGLKGHKVVGGMRASLYNAMTLEGVKKLIRFMKLFSEK
EEEEECCCCCHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YR
CC
>Mature Secondary Structure
MNEVFNFSAGPAMLPKQVLRQVKEELYSWNNMGVSVIEISHRSKEFLQLMQEAKQDMRDL
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LDITENYEVLFCHGGARAQFSAIPMNLLKTSSERVDYIITGYWAYNAAIEAKKYCDPRII
HHHCCCCEEEEEECCCCCEEHHCCHHHHHCCCCCCCEEEEEEEEECEEECHHHCCCCEEE
NVVGEKNGLHNIQPISKWDVSENSLYIHYCPNETIDGIAVYETPNFSDKIVVADCSSTLF
EEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCEEEEECCCHHH
SGPLNINRFGIIYATAQKNIGISGLTVIIIRKDLLKEPCLVVPSILNYKILADNFSMFNT
CCCCCCCEEEEEEEEECCCCCCCCEEEEEEEHHHHCCCCHHHHHHHCEEEEECCCCCCCC
PVTMSWYVASLIFKWLKKQGGLKEINKRNQEKSALLYDAIDSSNFYYNNISLSNRSYMNI
CEEHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHEEEEEEECCCCEEEEEEEECCCCEEEC
PFFLKNSKLNDLFLKESISFGLHGLKGHKVVGGMRASLYNAMTLEGVKKLIRFMKLFSEK
EEEEECCCCCHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA