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The map label for this gene is sdhB [H]

Identifier: 71892108

GI number: 71892108

Start: 401891

End: 402637

Strand: Direct

Name: sdhB [H]

Synonym: BPEN_340

Alternate gene names: 71892108

Gene position: 401891-402637 (Clockwise)

Preceding gene: 71892107

Following gene: 71892109

Centisome position: 50.77

GC content: 32.8

Gene sequence:

>747_bases
ATGCAAATTAAATTTTCCATTTACCGTTATCATCCTGAAATTAGTAAAAATGCCTGCATGAAAAATTATACACTTAATTT
ATTACATGCAAAAAATATGACATTATTAGATGCCTTAATTAAATTGAAAGAACAAGATCCAACTTTAACATTTCGGCGTT
CTTGCAGAGAAGGGGTATGTGGTTCTGATGGAATGAATATTAATGGCACAAATAATCTGGCATGCATTACTTCATTGAAG
CAATTATATGATAGCAATCATCAAAATGCAATTGTAGTACGTCCATTATCTGGATTTCCAATAATTCGTGATTTAGTAGT
AGATATGAGTCAATTCTTTCTTCAGTATGAAAGAGTACAACCATTTTTAATACATGAGCGTTCCAATCAACAACCTCAAT
TTCTTCACGAACATTTACAATCTCCAGAAGAACGTTCTAAATTAGATGGATCGTATGAATGCATATTATGCGCATGTTGT
TCTAGTGCTTGCCCCTCTTTTTGGTGGAATCCAGATAAATTTATTGGCCCTGCTGGATTATTGACCTTATATCGCTTTTT
GATGGACAGCCGCGATACTAACGATCAAGAACGCTTGGAACTCTTACAAGATTCTTTTAGTATTTTTCGTTGTCATAACA
TTATGAATTGCGTTAGTGTGTGTCCTAAAAAGTTAAATCCAGCCAAGGCTATAGGTCATATTAAACGAATATTAGCAAAA
AATTTAATTGGCATACATAACATTTAA

Upstream 100 bases:

>100_bases
AAAAATGATATTATGATTCGTCGTAATGTGAATATGCAACCAAAATTTCGTTCTCCTTTTCCTCCGAAAACTCGTGTTTA
TTAAAAAATGGAGTTTAAAT

Downstream 100 bases:

>100_bases
GAGAACAACAATAATTATAAAACACAATTTAACACAATACACAAACAACAGTCCAAATAAAATGAAATATATCTATGCAT
GATTATAGTAACTAATAAAA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MQIKFSIYRYHPEISKNACMKNYTLNLLHAKNMTLLDALIKLKEQDPTLTFRRSCREGVCGSDGMNINGTNNLACITSLK
QLYDSNHQNAIVVRPLSGFPIIRDLVVDMSQFFLQYERVQPFLIHERSNQQPQFLHEHLQSPEERSKLDGSYECILCACC
SSACPSFWWNPDKFIGPAGLLTLYRFLMDSRDTNDQERLELLQDSFSIFRCHNIMNCVSVCPKKLNPAKAIGHIKRILAK
NLIGIHNI

Sequences:

>Translated_248_residues
MQIKFSIYRYHPEISKNACMKNYTLNLLHAKNMTLLDALIKLKEQDPTLTFRRSCREGVCGSDGMNINGTNNLACITSLK
QLYDSNHQNAIVVRPLSGFPIIRDLVVDMSQFFLQYERVQPFLIHERSNQQPQFLHEHLQSPEERSKLDGSYECILCACC
SSACPSFWWNPDKFIGPAGLLTLYRFLMDSRDTNDQERLELLQDSFSIFRCHNIMNCVSVCPKKLNPAKAIGHIKRILAK
NLIGIHNI
>Mature_248_residues
MQIKFSIYRYHPEISKNACMKNYTLNLLHAKNMTLLDALIKLKEQDPTLTFRRSCREGVCGSDGMNINGTNNLACITSLK
QLYDSNHQNAIVVRPLSGFPIIRDLVVDMSQFFLQYERVQPFLIHERSNQQPQFLHEHLQSPEERSKLDGSYECILCACC
SSACPSFWWNPDKFIGPAGLLTLYRFLMDSRDTNDQERLELLQDSFSIFRCHNIMNCVSVCPKKLNPAKAIGHIKRILAK
NLIGIHNI

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=238, Percent_Identity=51.6806722689076, Blast_Score=251, Evalue=4e-67,
Organism=Escherichia coli, GI1786943, Length=238, Percent_Identity=63.4453781512605, Blast_Score=330, Evalue=6e-92,
Organism=Escherichia coli, GI1790596, Length=242, Percent_Identity=34.7107438016529, Blast_Score=145, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17533915, Length=238, Percent_Identity=50.8403361344538, Blast_Score=239, Evalue=7e-64,
Organism=Saccharomyces cerevisiae, GI6322987, Length=237, Percent_Identity=50.210970464135, Blast_Score=232, Evalue=4e-62,
Organism=Drosophila melanogaster, GI17137106, Length=238, Percent_Identity=52.1008403361345, Blast_Score=261, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24643156, Length=235, Percent_Identity=49.3617021276596, Blast_Score=241, Evalue=4e-64,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 28510; Mature: 28510

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKFSIYRYHPEISKNACMKNYTLNLLHAKNMTLLDALIKLKEQDPTLTFRRSCREGVC
CEEEEEEEEECCCHHHHHHHHHCEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
GSDGMNINGTNNLACITSLKQLYDSNHQNAIVVRPLSGFPIIRDLVVDMSQFFLQYERVQ
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
PFLIHERSNQQPQFLHEHLQSPEERSKLDGSYECILCACCSSACPSFWWNPDKFIGPAGL
CEEEECCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHCCHHHH
LTLYRFLMDSRDTNDQERLELLQDSFSIFRCHNIMNCVSVCPKKLNPAKAIGHIKRILAK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
NLIGIHNI
HHHHCCCC
>Mature Secondary Structure
MQIKFSIYRYHPEISKNACMKNYTLNLLHAKNMTLLDALIKLKEQDPTLTFRRSCREGVC
CEEEEEEEEECCCHHHHHHHHHCEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
GSDGMNINGTNNLACITSLKQLYDSNHQNAIVVRPLSGFPIIRDLVVDMSQFFLQYERVQ
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
PFLIHERSNQQPQFLHEHLQSPEERSKLDGSYECILCACCSSACPSFWWNPDKFIGPAGL
CEEEECCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHCCHHHH
LTLYRFLMDSRDTNDQERLELLQDSFSIFRCHNIMNCVSVCPKKLNPAKAIGHIKRILAK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
NLIGIHNI
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]