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The map label for this gene is argB

Identifier: 68535918

GI number: 68535918

Start: 1004655

End: 1005608

Strand: Direct

Name: argB

Synonym: jk0843

Alternate gene names: 68535918

Gene position: 1004655-1005608 (Clockwise)

Preceding gene: 68535917

Following gene: 68535919

Centisome position: 40.8

GC content: 64.26

Gene sequence:

>954_bases
ATGAACCCGAAACATACCCCCATCGATACCACCGGGCTGACCCCCGAGATGCGCAGCCACGTGCTGGCAGAGGCCCTGCC
GTGGCTGCTGCACTACCGCGACAAGATCGTGGTGGTGAAGTACGGCGGCAACGCCATGATCGACGAAGACCTGAAGCGTG
CCTTCGCCGCCGACATGGTCTTCCTGCGTGCCATCGGTGCTCGCCCGGTCGTGGTGCACGGCGGCGGACCCCAGATCAAC
GAGATGCTGAAGACCGTCGGACTGGAAGGCGAGTTCAAGGGCGGCTTCCGTGTGACCACACCGGAGGTCATGGAGTACGT
CCGCATGGTGCTATTCGGCAAGGTCGGCCGCGAGCTGGTCGGGCTGATCAACGAGCACGGCCCCTATGCCGTCGGTGCCT
CGGGCGAGGATGCCGGCCTGTTTACCGCCTCCAAGCGCATGATCACCGTCGATGGGGAAGAGGTCGACTTGGGTCGGGTG
GGGCAGATCGAGCACGTTGACGCCGAAAGCCTGATCGACCTCATCGACGCCGGCCGCATCCCCGTCGTCTCCACGGTCGC
ACCGGATGACCAGGGGCGGATCTACAACATCAACGCAGACACCGCCGCCGGTGCGCTGGCAGGTGCCCTGGGCGCCGAGA
GGCTCGTGATGCTCACCAATGTCAAGGGCTTGTACACCGACTGGCCAAACAAGGAATCGCTGGTATCCAGCCTGACCCCG
GAGCAGCTTTCCGATCTGCTGCCCAACCTCGATTCCGGCATGGTGCCCAAGATGGAGGCCTGCCTGGACGCGCTGCGCAG
TGGCGTGCAGGCCGCGCACGTTATCGACGGCCGTATTCCGCACTCCGTAATCTTGGAGCTGATGACCACCGGCGGTATCG
GCACCATGATCTGCCCCGCGGGCTGGGAAGACATTGCCAGCCCCGACATCAACTATCGGGAGGACCTCCCATGA

Upstream 100 bases:

>100_bases
TCCTACGTGGAGATCAACTCGGAGTACTCCACCTAAGACTCTTGAGCCACCAGAGCCGCCTGAACCACCCCGCACAACGG
ACCAACCAGGAAAACCCCAG

Downstream 100 bases:

>100_bases
CCCAGAACCTAGAGAACGCAACCAACGACTGGCAGGGCCACTGGAACGCCGCGCTGTTCGAAACCTACGGCACCCCGCCG
CGCGAGCTGGTTTCTGGCCG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNPKHTPIDTTGLTPEMRSHVLAEALPWLLHYRDKIVVVKYGGNAMIDEDLKRAFAADMVFLRAIGARPVVVHGGGPQIN
EMLKTVGLEGEFKGGFRVTTPEVMEYVRMVLFGKVGRELVGLINEHGPYAVGASGEDAGLFTASKRMITVDGEEVDLGRV
GQIEHVDAESLIDLIDAGRIPVVSTVAPDDQGRIYNINADTAAGALAGALGAERLVMLTNVKGLYTDWPNKESLVSSLTP
EQLSDLLPNLDSGMVPKMEACLDALRSGVQAAHVIDGRIPHSVILELMTTGGIGTMICPAGWEDIASPDINYREDLP

Sequences:

>Translated_317_residues
MNPKHTPIDTTGLTPEMRSHVLAEALPWLLHYRDKIVVVKYGGNAMIDEDLKRAFAADMVFLRAIGARPVVVHGGGPQIN
EMLKTVGLEGEFKGGFRVTTPEVMEYVRMVLFGKVGRELVGLINEHGPYAVGASGEDAGLFTASKRMITVDGEEVDLGRV
GQIEHVDAESLIDLIDAGRIPVVSTVAPDDQGRIYNINADTAAGALAGALGAERLVMLTNVKGLYTDWPNKESLVSSLTP
EQLSDLLPNLDSGMVPKMEACLDALRSGVQAAHVIDGRIPHSVILELMTTGGIGTMICPAGWEDIASPDINYREDLP
>Mature_317_residues
MNPKHTPIDTTGLTPEMRSHVLAEALPWLLHYRDKIVVVKYGGNAMIDEDLKRAFAADMVFLRAIGARPVVVHGGGPQIN
EMLKTVGLEGEFKGGFRVTTPEVMEYVRMVLFGKVGRELVGLINEHGPYAVGASGEDAGLFTASKRMITVDGEEVDLGRV
GQIEHVDAESLIDLIDAGRIPVVSTVAPDDQGRIYNINADTAAGALAGALGAERLVMLTNVKGLYTDWPNKESLVSSLTP
EQLSDLLPNLDSGMVPKMEACLDALRSGVQAAHVIDGRIPHSVILELMTTGGIGTMICPAGWEDIASPDINYREDLP

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=296, Percent_Identity=26.0135135135135, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI145693208, Length=233, Percent_Identity=32.1888412017167, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320913, Length=272, Percent_Identity=31.25, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_CORJK (Q4JW02)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250623.1
- HSSP:   Q9HTN2
- ProteinModelPortal:   Q4JW02
- SMR:   Q4JW02
- STRING:   Q4JW02
- GeneID:   3432212
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0843
- NMPDR:   fig|306537.3.peg.2035
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   CJEI306537:JK0843-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 34062; Mature: 34062

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: BINDING 97-97 BINDING 196-196

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPKHTPIDTTGLTPEMRSHVLAEALPWLLHYRDKIVVVKYGGNAMIDEDLKRAFAADMV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHH
FLRAIGARPVVVHGGGPQINEMLKTVGLEGEFKGGFRVTTPEVMEYVRMVLFGKVGRELV
HHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
GLINEHGPYAVGASGEDAGLFTASKRMITVDGEEVDLGRVGQIEHVDAESLIDLIDAGRI
HHHHCCCCEEECCCCCCCCEEEECCEEEEECCCEECCCCCCCCCCCCHHHHHHHHHCCCC
PVVSTVAPDDQGRIYNINADTAAGALAGALGAERLVMLTNVKGLYTDWPNKESLVSSLTP
CEEEEECCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCEEECCCCCHHHHHHHCCH
EQLSDLLPNLDSGMVPKMEACLDALRSGVQAAHVIDGRIPHSVILELMTTGGIGTMICPA
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEHHHCCCCCHHHHHHHHHCCCCCEEECCC
GWEDIASPDINYREDLP
CCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNPKHTPIDTTGLTPEMRSHVLAEALPWLLHYRDKIVVVKYGGNAMIDEDLKRAFAADMV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHH
FLRAIGARPVVVHGGGPQINEMLKTVGLEGEFKGGFRVTTPEVMEYVRMVLFGKVGRELV
HHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
GLINEHGPYAVGASGEDAGLFTASKRMITVDGEEVDLGRVGQIEHVDAESLIDLIDAGRI
HHHHCCCCEEECCCCCCCCEEEECCEEEEECCCEECCCCCCCCCCCCHHHHHHHHHCCCC
PVVSTVAPDDQGRIYNINADTAAGALAGALGAERLVMLTNVKGLYTDWPNKESLVSSLTP
CEEEEECCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCEEECCCCCHHHHHHHCCH
EQLSDLLPNLDSGMVPKMEACLDALRSGVQAAHVIDGRIPHSVILELMTTGGIGTMICPA
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEHHHCCCCCHHHHHHHHHCCCCCEEECCC
GWEDIASPDINYREDLP
CCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA