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The map label for this gene is rnr [H]

Identifier: 68535745

GI number: 68535745

Start: 806830

End: 808308

Strand: Direct

Name: rnr [H]

Synonym: jk0670

Alternate gene names: 68535745

Gene position: 806830-808308 (Clockwise)

Preceding gene: 68535744

Following gene: 68535746

Centisome position: 32.76

GC content: 67.14

Gene sequence:

>1479_bases
ATGAAACTTTTCGCCGCCGAGCTGAACTTCCGAGACATCGCCGAAGAATTCAAGCTGCCGGAACGCTTCCCGGAAGACGT
TCACGCCGATGCGCTGCAGGCCACTGACCAGCACGCCGAGCAGCGCCGCGACCTGCGGGATGTTCCATTTGTGACGATCG
ACCCTGCGGGCTCGATGGATCTGGACCAGGCGGTGAACATTCAGGACGCGCCGGATGGTGGCGCGGGCGGCGCTGGCGCG
GGGAGTGCGGCCGGCGACGGCACGGCTCGGTGGCGCGTGCTGTACGCCATCGCGGACGTGGCGGCCTTCGTGGATCCGGC
GGGGCCGCTGATGGCGGAATCCCTGCAGCGCGGCCAGACGATGTATCTGCCGGACGAGCCGACCCGCCTGCACCCAGCAG
AACTATCCGAGGGCAGTGCCTCGCTACTGCCGGACCAGACTCGCCCCGCCGTGGTGTGGGATATTCTGCTGCGCGCCGAC
GGCGAGGTCGCGGATTTCACCGTGTACCGCGCGCTGATCCGCTCCGTGAAGCGCTTCGACTACACCGAGGTGGAGGCGGA
CATGCACGGCGGCACGCTGCACCCCGCCATCGCGCAGTTGCCGGAGGTTGGCCGTGCGCGCCAGCGCTCTGACCTGCGAC
GCAAGGCCATCAACCTGCGTTTGCCCTCGATCTCCTTGGAGCGCACCCAGGATGACGATGGCGCCGAGCGCTACGTGCTG
GGCATCGACGAACGCCAGGAGATGAACGACTTCAACTCCGAGCTGTCCCTACTGGCCGGCATGTGCGCCGGCGAGATGAT
GGTCCGCGCGGGCGTGGGCATCCTGCGCACCCTGCCGCCTGCCGGGGACAAGGAAATCGCCGCCTTCGACCACTCCGCGC
ACGCCTTGGGGTTCGATCGCTCCGGCCGCCCGATCGGTGAATTGCTCGCTGATGTTGACGCCTCCACGCCGCGTGGCATG
GCACTCATGCGCGACGCGCAAAGCCTTCTGCGCGGGGCGGGGTATCAGCAGTTCGGCCTGGCTGGCGGGAGTGCTGAGGC
GGACGCGGAGCCCAGCATCCACGCCGGCATCGGCGGCCACTACGCGCACGTTACTGCACCCCTGCGCCGACTGGTGGACC
GCTTCGCCACGGAAATCTGCCTGGCGATCGCCAGCTCCCAGCCCATCCCGGAGTGGGTGAACTCCAACGCCGACCAGGTG
CTCAGCACCATGAAGTCCAGCGGCCAGACGGCCAGCGCCGTCGACCGCGCCTGCCTGAATCTCACCGAGGCGGTCGTCCT
GCAACCGTGGGTGGGCCAGAACTTCAACGCGACGGTGCTCAATAGTGACGGCGGAGACAAGGCGAAAGTCCTGGTCGAGG
AGCCGCCCATCTTGACGACTTGTGTGGGCGGCCCAGACGAGGCGTCAACAGTTAAAGTAACCTTGATCGAAGCCGAACCC
GCAGCGCGAAAGGTACGTTTCGCCTGGCCGGCCGATTAG

Upstream 100 bases:

>100_bases
CGCTCGGTTGGTTACTCGGCTGGGCGTGGGTTTCCTGCGTGGCCGGGGCACTTGGCTGGGTGCGTGGCCGGGGCGGAGCG
GTTGTGCCACTCTTGGAGTC

Downstream 100 bases:

>100_bases
GCAGGGGGCTGTCCGGCGCGTGTGGTACACATGACTTTATGAGCGAAAATGATGCGCAGAAGTGGTACTACGACACGAAG
ACCGGCCAGGTGAGCCAGGG

Product: putative ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MKLFAAELNFRDIAEEFKLPERFPEDVHADALQATDQHAEQRRDLRDVPFVTIDPAGSMDLDQAVNIQDAPDGGAGGAGA
GSAAGDGTARWRVLYAIADVAAFVDPAGPLMAESLQRGQTMYLPDEPTRLHPAELSEGSASLLPDQTRPAVVWDILLRAD
GEVADFTVYRALIRSVKRFDYTEVEADMHGGTLHPAIAQLPEVGRARQRSDLRRKAINLRLPSISLERTQDDDGAERYVL
GIDERQEMNDFNSELSLLAGMCAGEMMVRAGVGILRTLPPAGDKEIAAFDHSAHALGFDRSGRPIGELLADVDASTPRGM
ALMRDAQSLLRGAGYQQFGLAGGSAEADAEPSIHAGIGGHYAHVTAPLRRLVDRFATEICLAIASSQPIPEWVNSNADQV
LSTMKSSGQTASAVDRACLNLTEAVVLQPWVGQNFNATVLNSDGGDKAKVLVEEPPILTTCVGGPDEASTVKVTLIEAEP
AARKVRFAWPAD

Sequences:

>Translated_492_residues
MKLFAAELNFRDIAEEFKLPERFPEDVHADALQATDQHAEQRRDLRDVPFVTIDPAGSMDLDQAVNIQDAPDGGAGGAGA
GSAAGDGTARWRVLYAIADVAAFVDPAGPLMAESLQRGQTMYLPDEPTRLHPAELSEGSASLLPDQTRPAVVWDILLRAD
GEVADFTVYRALIRSVKRFDYTEVEADMHGGTLHPAIAQLPEVGRARQRSDLRRKAINLRLPSISLERTQDDDGAERYVL
GIDERQEMNDFNSELSLLAGMCAGEMMVRAGVGILRTLPPAGDKEIAAFDHSAHALGFDRSGRPIGELLADVDASTPRGM
ALMRDAQSLLRGAGYQQFGLAGGSAEADAEPSIHAGIGGHYAHVTAPLRRLVDRFATEICLAIASSQPIPEWVNSNADQV
LSTMKSSGQTASAVDRACLNLTEAVVLQPWVGQNFNATVLNSDGGDKAKVLVEEPPILTTCVGGPDEASTVKVTLIEAEP
AARKVRFAWPAD
>Mature_492_residues
MKLFAAELNFRDIAEEFKLPERFPEDVHADALQATDQHAEQRRDLRDVPFVTIDPAGSMDLDQAVNIQDAPDGGAGGAGA
GSAAGDGTARWRVLYAIADVAAFVDPAGPLMAESLQRGQTMYLPDEPTRLHPAELSEGSASLLPDQTRPAVVWDILLRAD
GEVADFTVYRALIRSVKRFDYTEVEADMHGGTLHPAIAQLPEVGRARQRSDLRRKAINLRLPSISLERTQDDDGAERYVL
GIDERQEMNDFNSELSLLAGMCAGEMMVRAGVGILRTLPPAGDKEIAAFDHSAHALGFDRSGRPIGELLADVDASTPRGM
ALMRDAQSLLRGAGYQQFGLAGGSAEADAEPSIHAGIGGHYAHVTAPLRRLVDRFATEICLAIASSQPIPEWVNSNADQV
LSTMKSSGQTASAVDRACLNLTEAVVLQPWVGQNFNATVLNSDGGDKAKVLVEEPPILTTCVGGPDEASTVKVTLIEAEP
AARKVRFAWPAD

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI134288890, Length=361, Percent_Identity=24.0997229916898, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI87082383, Length=352, Percent_Identity=27.5568181818182, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17553506, Length=366, Percent_Identity=24.3169398907104, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324552, Length=378, Percent_Identity=25.1322751322751, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24649634, Length=352, Percent_Identity=25, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 52790; Mature: 52790

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFAAELNFRDIAEEFKLPERFPEDVHADALQATDQHAEQRRDLRDVPFVTIDPAGSMD
CCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
LDQAVNIQDAPDGGAGGAGAGSAAGDGTARWRVLYAIADVAAFVDPAGPLMAESLQRGQT
HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCE
MYLPDEPTRLHPAELSEGSASLLPDQTRPAVVWDILLRADGEVADFTVYRALIRSVKRFD
EECCCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
YTEVEADMHGGTLHPAIAQLPEVGRARQRSDLRRKAINLRLPSISLERTQDDDGAERYVL
CHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCCCCCCCEEEE
GIDERQEMNDFNSELSLLAGMCAGEMMVRAGVGILRTLPPAGDKEIAAFDHSAHALGFDR
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEECCCCCEECCCC
SGRPIGELLADVDASTPRGMALMRDAQSLLRGAGYQQFGLAGGSAEADAEPSIHAGIGGH
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCEECCCCCC
YAHVTAPLRRLVDRFATEICLAIASSQPIPEWVNSNADQVLSTMKSSGQTASAVDRACLN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
LTEAVVLQPWVGQNFNATVLNSDGGDKAKVLVEEPPILTTCVGGPDEASTVKVTLIEAEP
HHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEECCCEEEEECCCCCCCCEEEEEEEECCC
AARKVRFAWPAD
CCCEEEEECCCC
>Mature Secondary Structure
MKLFAAELNFRDIAEEFKLPERFPEDVHADALQATDQHAEQRRDLRDVPFVTIDPAGSMD
CCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
LDQAVNIQDAPDGGAGGAGAGSAAGDGTARWRVLYAIADVAAFVDPAGPLMAESLQRGQT
HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCE
MYLPDEPTRLHPAELSEGSASLLPDQTRPAVVWDILLRADGEVADFTVYRALIRSVKRFD
EECCCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
YTEVEADMHGGTLHPAIAQLPEVGRARQRSDLRRKAINLRLPSISLERTQDDDGAERYVL
CHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCCCCCCCEEEE
GIDERQEMNDFNSELSLLAGMCAGEMMVRAGVGILRTLPPAGDKEIAAFDHSAHALGFDR
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEECCCCCEECCCC
SGRPIGELLADVDASTPRGMALMRDAQSLLRGAGYQQFGLAGGSAEADAEPSIHAGIGGH
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCEECCCCCC
YAHVTAPLRRLVDRFATEICLAIASSQPIPEWVNSNADQVLSTMKSSGQTASAVDRACLN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
LTEAVVLQPWVGQNFNATVLNSDGGDKAKVLVEEPPILTTCVGGPDEASTVKVTLIEAEP
HHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEECCCEEEEECCCCCCCCEEEEEEEECCC
AARKVRFAWPAD
CCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]