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The map label for this gene is rnhA [C]

Identifier: 68535744

GI number: 68535744

Start: 804931

End: 806226

Strand: Direct

Name: rnhA [C]

Synonym: jk0669

Alternate gene names: 68535744

Gene position: 804931-806226 (Clockwise)

Preceding gene: 68535743

Following gene: 68535745

Centisome position: 32.69

GC content: 66.28

Gene sequence:

>1296_bases
ATGCGCTTAGACGTGGAATGCGACGGAGGATCCCGCGGTAACCCGGGCATCGCCGGTTGCGGAAGTTCGGTCCTGGAGGG
TGACCAGGAAGTAGCCGCACGCTGGGAGTTCATCGCCAAGGCTACGAATAATGTGGCGGAGTACCAGGGGCTCATCAATG
CTCTGGAGCTGGCCATCGAGGTGGCGAAGATACGTGGGGTGGCTGCCGGGGATCTGGAGATCCAGGTGCGCATGGATTCC
AAGCTCGTCGTCGAGCAAATGAGCGGCCGCTGGAAGATCAAGCACCCTGACATGAAGCCCCTGGCCGCGCGGGTCAAGGA
ACTTGAGGCCACCCTCGCCGCCGTCACCTACAACTGGGTGCCGCGCGCGCAGAACAAACGCGCTGACGAGCTGGCCAATC
GCGCCATGGATGATGGGGTTGGGGGCCGCTGGTTTGATGACGCCCTCTCGTTCCAACCCGCCGCCGACTCAGCCGAAGCC
GACGGGGATGCCGCGCCGGCACCTGCAGGGACTGCGGGCGCGGAGGCCACTGGTGCGGAGGCCGTGACCGATGCCGCGAG
CGCGCCGGAATGGCACCCCGGCGGGAAGCCGACCCGCCTGTGGGTGCTGCGGCACGGGCAGACGGAGATGAGCGTGAAGA
AGCAGTTCTCCGGGCTCTCCGACCCGGAGCTGACCTCCCACGGGCATGAGCAGGCTCGACGGGCCGCGGCCTACGTGGCC
GGACAGCTGGCAGGCGGCGCGGGTGGCAGCGCTGGCCCGGTGGCGATCTACAGCTCCCCGCTGAAGCGCACCCGCCAGAC
CGCGGAGGCCGTGGCTGAGGCACTTGCCACCTCTCCCCGCGTTCACGTGACCGAGGCCCTGATCGAAATGAACTTCGGAG
ACTGGGAAGGCCGCACCTTCGCCGAGGTCATGGATGAATTCCCGCTCGAGCACGACGCCTGCTTCTGGGATAGCTCCGCC
GCCCCCAGCGGAGGTGAAAGTCCCGACGACGTGCTCGCCCGCGTCCGCCCCTTCCTCCGCGACGTGGCTCGCAACCACCC
CGGCGAGGACGTCGTGCTGGTCAGCCACGTCACGCCCATCAAATCCATCCTGCGTCACGCCCTCTGCGCAAGCGGTGCAC
TGTACCGCACGCTGCACCTGGATCTGGCAGGCTTGAGCGTCATCGAAATCTTCCCGGATGGCTCGAATGGTTCCGGGGGA
GAAGTGGGCGTCAATAACAAGGGCAGCAACAAAGACAGCGCTGTGGTGCGAAGGGTCAACGATACGCACTTCCTCGATGG
AGAAACCGTGCGCTAG

Upstream 100 bases:

>100_bases
GGCAGAGGACGGTTCCGGGGTAGTGCCGCGATGCCCTGAATGCAATGTCTTGCTACTGCGATAGAGTGACCTGAAGACGA
CAAGATGAGGGTGATGAGTG

Downstream 100 bases:

>100_bases
AGTTAAGCCTTGTCGAGACGGCCGGGCGATCGCGGCGCACGGAACCACCCTGTACACGGGGCAGGCCGGGCGCGGAGGAA
AGTCCGGACTCCACAGGGCA

Product: bifunctional RNase H/acid phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MRLDVECDGGSRGNPGIAGCGSSVLEGDQEVAARWEFIAKATNNVAEYQGLINALELAIEVAKIRGVAAGDLEIQVRMDS
KLVVEQMSGRWKIKHPDMKPLAARVKELEATLAAVTYNWVPRAQNKRADELANRAMDDGVGGRWFDDALSFQPAADSAEA
DGDAAPAPAGTAGAEATGAEAVTDAASAPEWHPGGKPTRLWVLRHGQTEMSVKKQFSGLSDPELTSHGHEQARRAAAYVA
GQLAGGAGGSAGPVAIYSSPLKRTRQTAEAVAEALATSPRVHVTEALIEMNFGDWEGRTFAEVMDEFPLEHDACFWDSSA
APSGGESPDDVLARVRPFLRDVARNHPGEDVVLVSHVTPIKSILRHALCASGALYRTLHLDLAGLSVIEIFPDGSNGSGG
EVGVNNKGSNKDSAVVRRVNDTHFLDGETVR

Sequences:

>Translated_431_residues
MRLDVECDGGSRGNPGIAGCGSSVLEGDQEVAARWEFIAKATNNVAEYQGLINALELAIEVAKIRGVAAGDLEIQVRMDS
KLVVEQMSGRWKIKHPDMKPLAARVKELEATLAAVTYNWVPRAQNKRADELANRAMDDGVGGRWFDDALSFQPAADSAEA
DGDAAPAPAGTAGAEATGAEAVTDAASAPEWHPGGKPTRLWVLRHGQTEMSVKKQFSGLSDPELTSHGHEQARRAAAYVA
GQLAGGAGGSAGPVAIYSSPLKRTRQTAEAVAEALATSPRVHVTEALIEMNFGDWEGRTFAEVMDEFPLEHDACFWDSSA
APSGGESPDDVLARVRPFLRDVARNHPGEDVVLVSHVTPIKSILRHALCASGALYRTLHLDLAGLSVIEIFPDGSNGSGG
EVGVNNKGSNKDSAVVRRVNDTHFLDGETVR
>Mature_431_residues
MRLDVECDGGSRGNPGIAGCGSSVLEGDQEVAARWEFIAKATNNVAEYQGLINALELAIEVAKIRGVAAGDLEIQVRMDS
KLVVEQMSGRWKIKHPDMKPLAARVKELEATLAAVTYNWVPRAQNKRADELANRAMDDGVGGRWFDDALSFQPAADSAEA
DGDAAPAPAGTAGAEATGAEAVTDAASAPEWHPGGKPTRLWVLRHGQTEMSVKKQFSGLSDPELTSHGHEQARRAAAYVA
GQLAGGAGGSAGPVAIYSSPLKRTRQTAEAVAEALATSPRVHVTEALIEMNFGDWEGRTFAEVMDEFPLEHDACFWDSSA
APSGGESPDDVLARVRPFLRDVARNHPGEDVVLVSHVTPIKSILRHALCASGALYRTLHLDLAGLSVIEIFPDGSNGSGG
EVGVNNKGSNKDSAVVRRVNDTHFLDGETVR

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR012337
- InterPro:   IPR014636
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00300 PGAM; PF00075 RnaseH [H]

EC number: 3.1.3.73 [C]

Molecular weight: Translated: 45712; Mature: 45712

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDVECDGGSRGNPGIAGCGSSVLEGDQEVAARWEFIAKATNNVAEYQGLINALELAIE
CEEEEECCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAKIRGVAAGDLEIQVRMDSKLVVEQMSGRWKIKHPDMKPLAARVKELEATLAAVTYNWV
HHHHCCEEECCEEEEEEECCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCC
PRAQNKRADELANRAMDDGVGGRWFDDALSFQPAADSAEADGDAAPAPAGTAGAEATGAE
CCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AVTDAASAPEWHPGGKPTRLWVLRHGQTEMSVKKQFSGLSDPELTSHGHEQARRAAAYVA
HHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHH
GQLAGGAGGSAGPVAIYSSPLKRTRQTAEAVAEALATSPRVHVTEALIEMNFGDWEGRTF
HHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHH
AEVMDEFPLEHDACFWDSSAAPSGGESPDDVLARVRPFLRDVARNHPGEDVVLVSHVTPI
HHHHHHCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHH
KSILRHALCASGALYRTLHLDLAGLSVIEIFPDGSNGSGGEVGVNNKGSNKDSAVVRRVN
HHHHHHHHHHCCHHHEEEEHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHEECC
DTHFLDGETVR
CCEECCCCCCC
>Mature Secondary Structure
MRLDVECDGGSRGNPGIAGCGSSVLEGDQEVAARWEFIAKATNNVAEYQGLINALELAIE
CEEEEECCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAKIRGVAAGDLEIQVRMDSKLVVEQMSGRWKIKHPDMKPLAARVKELEATLAAVTYNWV
HHHHCCEEECCEEEEEEECCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCC
PRAQNKRADELANRAMDDGVGGRWFDDALSFQPAADSAEADGDAAPAPAGTAGAEATGAE
CCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AVTDAASAPEWHPGGKPTRLWVLRHGQTEMSVKKQFSGLSDPELTSHGHEQARRAAAYVA
HHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHH
GQLAGGAGGSAGPVAIYSSPLKRTRQTAEAVAEALATSPRVHVTEALIEMNFGDWEGRTF
HHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHH
AEVMDEFPLEHDACFWDSSAAPSGGESPDDVLARVRPFLRDVARNHPGEDVVLVSHVTPI
HHHHHHCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHH
KSILRHALCASGALYRTLHLDLAGLSVIEIFPDGSNGSGGEVGVNNKGSNKDSAVVRRVN
HHHHHHHHHHCCHHHEEEEHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHEECC
DTHFLDGETVR
CCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]