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The map label for this gene is acoR [H]

Identifier: 66767026

GI number: 66767026

Start: 826159

End: 828201

Strand: Reverse

Name: acoR [H]

Synonym: XC_0689

Alternate gene names: 66767026

Gene position: 828201-826159 (Counterclockwise)

Preceding gene: 66767027

Following gene: 66767025

Centisome position: 16.09

GC content: 68.28

Gene sequence:

>2043_bases
ATGCGGTTTGAGCATGGGCCCGGTTTGTGTCTCTACTGGCGCCTCGCGCCCTTCGAGGAACGCTGGCCCATGTCCGAGCC
GAGCGTTGTGGCCAGCACCTCCATCGTCCTGCCGGAGATCGAGCCGGAACTGCTCCAGCAGATCCGCCGGCTGCGCGATA
TCGCGCCGCTGGCGGCTCCGCTGTCGCGTTCCTGGCGTCGCTGCCTGGAGGACTACGCCTTGTTGCCGGAGGCGCTGCCG
GACCCGATGGTGCATGACGCCCTGCATGTGCGCGAGCGCCAGCAACGCCTGGGCGATGTCCTGCGGATCGCCCGGGTGGA
GATGGAAAACCTCTACGAGCAGATCGCCGGCAGCGGCTATGCGGTGATCTTTGCCGACGCCGACGCCACCGTGCTGCACA
GCGTGCACGACCCTACCCTGCTGCGCGAATTCCGCCAGGTGGGCCTGTTTGCCGGCGCCAGCTGGGCGGAGCGCCATCAG
GGCACCAACGGGCTGGGCACCTGCGCGGCCGAGCGCACCGCGGTGAGCGTGCACCGCGGCGAGCATTACCTGACCCGGCA
CCTGCCGCTGTCGTGCTGCAGCGCGCCGATCCTGGACGCGCACGGCGGGCTGCTGGCGGTGCTGGATGCCTCCACCCCCA
ATGCCCAGGACGGCAAGCAGATCCAGCGCCATACCGTGGCGCTGGTGAGCATGTCGGCGGCGCAGATCTCGCGCTCGCAC
TTCCTCAACCAGTTCGGTCACGCCTTCATCCTGCGCTTCCACAGCCGCCCGGAGTTCGCCGGCCTGCTGCATGAAGCACT
GATCGCCATCGGTGCCGATGGCCGCGTGCTGGCCGTGAACGAGGCGGTGCTGGAGCAGCTGGGCAAGCTGGACCGCAGCC
AGCTGGTGGGCCGCGACATCTCGCAGGTGATGCAGCTGGACTTCGACACCATCGAGCACCGCGCCGGCAGCGATGCCGGC
ACCTTGTGGTCGATCCGTTGCGCCTGCCACGGCCGCCGCTTCTATGCGCTGGTGCGGCCGCCGCGTGCGCGCCCGGCGCT
GCCGGCAGTGGGCGGGCCGGCACAGCCGGCCACGGAAACCGAATTGAATCCTGGCGAGCATGTCGGTTCGGATCCGCGCA
TGCGCCACAACCTGGCCAATGCGCTGAAACTGGCGGCGCACCGCGTCTCCATCCTGCTGCGCGGCGACACCGGCACCGGC
AAGGAGGAGTTTGCCAAGGCCGTGCACCGCGGTTCGCCCTGGGCAAGCGGCGCGTTTGTGGCGATCAACTGCGCGGCCAT
TCCCGAGGCGCTGATCGAAAGCGAATTGTTCGGCTATGCGCGCGGCGCATTTACCGACGCCGCGCGCGAAGGCCGCCACG
GCAAGTTGCTGCAGGCCAGCGGCGGCACCTTGTTTCTGGATGAAATCGGCGACATGCCGCTGCCGTTGCAAAGCCGCCTG
CTGCGTGTGCTGGAAGAACAATGCGTTACCCCACTCGGCAGCGAGCGTGCGGTGCCGCTGGAGTTGCACGTGATCAGCGC
CAGCCACCGAGACCTGGCCCAGCGCGTCTCCGCGGGCGAGTTTCGCGAAGACCTGTATTACCGACTCAACGGCGTGGTGC
TGCATCTGCCGCCCTTGCGCGAGCGCAGCGACAAGGCCGAGTTGATCCGCACCCTGCTGCGCGAAGAGAACAACGAGCGC
GGTGTCCGCATCAGCGAAGAGGCCATGCACAAACTGCTCAGCTACGCGTGGCCCGGCAATCTGCGCCAGCTGCGCAACGT
GCTGCGCACCGCCGCGGTGCTGTGCAGCGATGCGGTGATTCGCCTGCCCAACCTGCCGCAGGAAATCGTCGATGCCGGCA
GTGCGCCGTGCCTGGTCGATGGCCGCGCCGTGGCCGCCGACGACATGCCCGGGCGCGTGGCGCTGGACCAGGCCGAGCGC
CTGGTCCTGCAGCAGCAGCTCGAACGACACCGTTGGAATGTCAGCCGCACCGCTGACGCGCTGGGCATCAGCCGCAATAC
GCTGTATCGCAAGCTGCGCAAGCATGGGTTGGAAACGGGGTGA

Upstream 100 bases:

>100_bases
GTGCAAACCGCCGTTGCGCGCGTCATCCCACCGCGCCAGCCGTGGTCCGGCCCGCCATACCGCAGCAGGCATTGCGTCAC
CGCCGTCGCGCTTTGCTGCG

Downstream 100 bases:

>100_bases
CTGAGCGGCGGGGATTGGTGATTGGGGATTGGGGATTCGTCAAAGCCAAGGCAGTGGCTTTGCGCTGACATTTAGAGCGA
TCAACACAATTATTTCTTGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MRFEHGPGLCLYWRLAPFEERWPMSEPSVVASTSIVLPEIEPELLQQIRRLRDIAPLAAPLSRSWRRCLEDYALLPEALP
DPMVHDALHVRERQQRLGDVLRIARVEMENLYEQIAGSGYAVIFADADATVLHSVHDPTLLREFRQVGLFAGASWAERHQ
GTNGLGTCAAERTAVSVHRGEHYLTRHLPLSCCSAPILDAHGGLLAVLDASTPNAQDGKQIQRHTVALVSMSAAQISRSH
FLNQFGHAFILRFHSRPEFAGLLHEALIAIGADGRVLAVNEAVLEQLGKLDRSQLVGRDISQVMQLDFDTIEHRAGSDAG
TLWSIRCACHGRRFYALVRPPRARPALPAVGGPAQPATETELNPGEHVGSDPRMRHNLANALKLAAHRVSILLRGDTGTG
KEEFAKAVHRGSPWASGAFVAINCAAIPEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQSRL
LRVLEEQCVTPLGSERAVPLELHVISASHRDLAQRVSAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENNER
GVRISEEAMHKLLSYAWPGNLRQLRNVLRTAAVLCSDAVIRLPNLPQEIVDAGSAPCLVDGRAVAADDMPGRVALDQAER
LVLQQQLERHRWNVSRTADALGISRNTLYRKLRKHGLETG

Sequences:

>Translated_680_residues
MRFEHGPGLCLYWRLAPFEERWPMSEPSVVASTSIVLPEIEPELLQQIRRLRDIAPLAAPLSRSWRRCLEDYALLPEALP
DPMVHDALHVRERQQRLGDVLRIARVEMENLYEQIAGSGYAVIFADADATVLHSVHDPTLLREFRQVGLFAGASWAERHQ
GTNGLGTCAAERTAVSVHRGEHYLTRHLPLSCCSAPILDAHGGLLAVLDASTPNAQDGKQIQRHTVALVSMSAAQISRSH
FLNQFGHAFILRFHSRPEFAGLLHEALIAIGADGRVLAVNEAVLEQLGKLDRSQLVGRDISQVMQLDFDTIEHRAGSDAG
TLWSIRCACHGRRFYALVRPPRARPALPAVGGPAQPATETELNPGEHVGSDPRMRHNLANALKLAAHRVSILLRGDTGTG
KEEFAKAVHRGSPWASGAFVAINCAAIPEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQSRL
LRVLEEQCVTPLGSERAVPLELHVISASHRDLAQRVSAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENNER
GVRISEEAMHKLLSYAWPGNLRQLRNVLRTAAVLCSDAVIRLPNLPQEIVDAGSAPCLVDGRAVAADDMPGRVALDQAER
LVLQQQLERHRWNVSRTADALGISRNTLYRKLRKHGLETG
>Mature_680_residues
MRFEHGPGLCLYWRLAPFEERWPMSEPSVVASTSIVLPEIEPELLQQIRRLRDIAPLAAPLSRSWRRCLEDYALLPEALP
DPMVHDALHVRERQQRLGDVLRIARVEMENLYEQIAGSGYAVIFADADATVLHSVHDPTLLREFRQVGLFAGASWAERHQ
GTNGLGTCAAERTAVSVHRGEHYLTRHLPLSCCSAPILDAHGGLLAVLDASTPNAQDGKQIQRHTVALVSMSAAQISRSH
FLNQFGHAFILRFHSRPEFAGLLHEALIAIGADGRVLAVNEAVLEQLGKLDRSQLVGRDISQVMQLDFDTIEHRAGSDAG
TLWSIRCACHGRRFYALVRPPRARPALPAVGGPAQPATETELNPGEHVGSDPRMRHNLANALKLAAHRVSILLRGDTGTG
KEEFAKAVHRGSPWASGAFVAINCAAIPEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQSRL
LRVLEEQCVTPLGSERAVPLELHVISASHRDLAQRVSAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENNER
GVRISEEAMHKLLSYAWPGNLRQLRNVLRTAAVLCSDAVIRLPNLPQEIVDAGSAPCLVDGRAVAADDMPGRVALDQAER
LVLQQQLERHRWNVSRTADALGISRNTLYRKLRKHGLETG

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=316, Percent_Identity=44.9367088607595, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1789233, Length=436, Percent_Identity=34.6330275229358, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI1788550, Length=330, Percent_Identity=38.1818181818182, Blast_Score=222, Evalue=8e-59,
Organism=Escherichia coli, GI1790299, Length=330, Percent_Identity=40.6060606060606, Blast_Score=213, Evalue=5e-56,
Organism=Escherichia coli, GI1790437, Length=311, Percent_Identity=40.1929260450161, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1786524, Length=329, Percent_Identity=41.0334346504559, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87082117, Length=329, Percent_Identity=37.9939209726444, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1787583, Length=318, Percent_Identity=38.0503144654088, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1789087, Length=321, Percent_Identity=36.7601246105919, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI87082152, Length=252, Percent_Identity=40.8730158730159, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI87081858, Length=663, Percent_Identity=24.73604826546, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI87081872, Length=299, Percent_Identity=34.7826086956522, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1789828, Length=234, Percent_Identity=38.8888888888889, Blast_Score=138, Evalue=1e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 75093; Mature: 75093

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFEHGPGLCLYWRLAPFEERWPMSEPSVVASTSIVLPEIEPELLQQIRRLRDIAPLAAP
CCCCCCCCEEEEEEECCCHHCCCCCCCCEEEECEEECCCCCHHHHHHHHHHHHHHHHHHH
LSRSWRRCLEDYALLPEALPDPMVHDALHVRERQQRLGDVLRIARVEMENLYEQIAGSGY
HHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
AVIFADADATVLHSVHDPTLLREFRQVGLFAGASWAERHQGTNGLGTCAAERTAVSVHRG
EEEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHCC
EHYLTRHLPLSCCSAPILDAHGGLLAVLDASTPNAQDGKQIQRHTVALVSMSAAQISRSH
CHHHHHCCCHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FLNQFGHAFILRFHSRPEFAGLLHEALIAIGADGRVLAVNEAVLEQLGKLDRSQLVGRDI
HHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCHHHHHHHHH
SQVMQLDFDTIEHRAGSDAGTLWSIRCACHGRRFYALVRPPRARPALPAVGGPAQPATET
HHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
ELNPGEHVGSDPRMRHNLANALKLAAHRVSILLRGDTGTGKEEFAKAVHRGSPWASGAFV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEE
AINCAAIPEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQSRL
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEHHCCCCCCCCHHHHH
LRVLEEQCVTPLGSERAVPLELHVISASHRDLAQRVSAGEFREDLYYRLNGVVLHLPPLR
HHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
ERSDKAELIRTLLREENNERGVRISEEAMHKLLSYAWPGNLRQLRNVLRTAAVLCSDAVI
CCCCHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RLPNLPQEIVDAGSAPCLVDGRAVAADDMPGRVALDQAERLVLQQQLERHRWNVSRTADA
CCCCCCHHHHCCCCCCEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
LGISRNTLYRKLRKHGLETG
HCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRFEHGPGLCLYWRLAPFEERWPMSEPSVVASTSIVLPEIEPELLQQIRRLRDIAPLAAP
CCCCCCCCEEEEEEECCCHHCCCCCCCCEEEECEEECCCCCHHHHHHHHHHHHHHHHHHH
LSRSWRRCLEDYALLPEALPDPMVHDALHVRERQQRLGDVLRIARVEMENLYEQIAGSGY
HHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
AVIFADADATVLHSVHDPTLLREFRQVGLFAGASWAERHQGTNGLGTCAAERTAVSVHRG
EEEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHCC
EHYLTRHLPLSCCSAPILDAHGGLLAVLDASTPNAQDGKQIQRHTVALVSMSAAQISRSH
CHHHHHCCCHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FLNQFGHAFILRFHSRPEFAGLLHEALIAIGADGRVLAVNEAVLEQLGKLDRSQLVGRDI
HHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCHHHHHHHHH
SQVMQLDFDTIEHRAGSDAGTLWSIRCACHGRRFYALVRPPRARPALPAVGGPAQPATET
HHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
ELNPGEHVGSDPRMRHNLANALKLAAHRVSILLRGDTGTGKEEFAKAVHRGSPWASGAFV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEE
AINCAAIPEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQSRL
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEHHCCCCCCCCHHHHH
LRVLEEQCVTPLGSERAVPLELHVISASHRDLAQRVSAGEFREDLYYRLNGVVLHLPPLR
HHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
ERSDKAELIRTLLREENNERGVRISEEAMHKLLSYAWPGNLRQLRNVLRTAAVLCSDAVI
CCCCHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RLPNLPQEIVDAGSAPCLVDGRAVAADDMPGRVALDQAERLVLQQQLERHRWNVSRTADA
CCCCCCHHHHCCCCCCEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
LGISRNTLYRKLRKHGLETG
HCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]