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The map label for this gene is dsbD [H]

Identifier: 66766870

GI number: 66766870

Start: 626891

End: 629197

Strand: Reverse

Name: dsbD [H]

Synonym: XC_0531

Alternate gene names: 66766870

Gene position: 629197-626891 (Counterclockwise)

Preceding gene: 66766871

Following gene: 66766869

Centisome position: 12.22

GC content: 71.0

Gene sequence:

>2307_bases
ATGAAGTCCCTGTCCCGCTGGATCGCCCGCTGCGCCGTACTGGTCGCGCCCCTGTTCGTCGCCTTGCCGCTGCTGCTGAC
CGCGCCAGCGGCGCAGGCGGTTACCGAGGCAGACCTGCTGCCGGTGGACCAGGCCTTCGCACTGAGCGCCAAGGCCGATG
GACGTGACCGCATCGCGCTGACCTGGAAGATCGCCCCGGGTTACTACCTGTACCGGCATCGCATCAGCGTCAAATCCGGC
CAGGGCTTCACTGCCGGTGCGCTGGATCTGCCTGAAGGCGAGAGCAAGCACGACGAATTCTTCGGCCAGGTGCAGACCTA
CCGCACCGCGCTGCAGGCCAGCCTGGCCGGCAAGGCCGCGCCCGGCCAGCGCAGCGCGATCCTGCAGGTGCAATACCAGG
GCTGCGCCGATGCCGGCGTGTGCTACCCGCCGCAACGCCGCGAACTGCGCGTGGACCTGCCCGACGCGCCAACCACCGCT
CCGCCGCGCGAAAGCCTGGGCGCCCTGGTGCCGCGCGGCCCCAGTGGCGCACGGCTGTTCGGCGCGCCCGGCCAGACTGC
CGGCGTGGACGCCCTGCCGCTGCCGGCCGACCAGGCCTTCAACTTCGAGGCGATCGTCGGCGACGGCAACAGCCTGCTGC
TGCGTTTCACCCCGGCCCCCGGCTACTACCTCTACCGCGACCGCACCTCGCTGTCGCTGGAAGGCACCAGCGACATCCGC
ACCGGCCTGCCGCGGTGGCCGCAGGGCCGCACCCACCGCGACGAGCACTTCGGCGATGTGGTGGTGTATTTCGACCAGGC
CGAAGTCACCCTGCCGCTGCTGCGCGACCGCCCCGATCCGGCCCGCGTGACGCTGGTGGCCACCTTCCAGGGCTGTCAGT
CCGATGGCATCTGCTACCCGCCGATGACCCGGCGCGTGCGCCTGGACCTGCCGGCCGGCACGGTGTCGCCGCACAACCAG
GCCACTGCCACCCCGCTGCTGATCTCGCCGCTGTCGGCCGGTGAAGTGGCCGCCGAGCGCGCCGCCCCAGGGCCGCCTGC
GGATGCCGCACCCGGCCCCGACGCAACGGCCGGCAACCCGGAGCGCAGCCGCCCACCGCACCTGGAGCGCAACCTGCTCG
CCATCCTGCTGCTGGCGCTGGCCGGCGGGCTGGTGTTGAACCTGATGCCCTGCGTGCTGCCGATCCTGTCGCTGAAGGTG
CTGGGCCTGGCCCACAGCGGCGAGAGCCGCAACCACGCGCGCAGCCACGCCATCTGGTATTCGCTGGGCGTGCTGGTGTC
CTTCGCTGCGATCGGCGGGCTGGTGATCGGCCTGCGCGCTGCCGGCCAGGCTGCCGGCTGGGGCTTCCAGCTGCAGCAGC
CGTGGTTCGTGGCCGCGTTGGCCTACCTGATGTTCGCGGTGGGCCTGAGCCTGTCGGGCGTGTTCACGCTGGGCAGCAAC
CTGGGCGGCATCGGCCAATCGCTGGCTGCGCGCAACGGGCCGCTGGGCGACTTCTTTACCGGCGTGCTGGCCTGCGTGGT
CGCCAGCCCGTGCATTGCACCGTTCATGGGCACCGCGCTGGCGTATGCGTTCACCGCGCCTGCGCCGCTGGCGATGCTGG
TGTTCCTGACCCTGGGCCTGGGCCTGGCGCTGCCGTTCCTGCTGATCGGCTTCATCCCCTCGCTGGCCCGGCGGCTGCCC
ACGCCCGGCGCCTGGATGGAGACGCTCAAGCAGGTGCTGGCCTTCCCGATGTACCTCACCGCGATCTGGCTGCTGTGGGT
GCTGGGCAAGCAGCGTGGCGTGGATGCGCTGGCGCTGATGCTGGTCGGCGCCACCTTGCTGGCGCTGGGCCTGTGGTGGT
TCGAACGCAGCCGCTGGAACAGCCATCGCCTGGGCATGGGCCTGGCCGCGGCGATGCTGGTGCTGGCGATCGTGCCGGTG
GTGGCGGTCACCCGCCTCAGCCTGCCGCGTGCCACCGCCACCGAAGGCAGCGTCACCTACACCCCCGAGTTGCTGGACCG
CCTGCGCGCAGACAACCGCGTGGTGTTCGTCAACATGACCGCCGACTGGTGCGTGACCTGCAAGGCCAACGAAAAGAACG
TGCTGAGCAGCACCGACTTCCGCGACGCGTTGCGCCGCGTGGATGCGGTCTACATGAAGGGCGACTGGACCAACGTCGAC
CCGAAGATCAGCGCCTTCCTCGACCAGCACCAGGCAGTCGGCGTGCCGCTGTACGTGGTCTACGGCCCGGGCGCACCGCC
GGCGGTACTGCCCACCGTGCTCACCGGCGCCATCACCGAAGATGCGCTGCTGCGCGCAGCGCGCTGA

Upstream 100 bases:

>100_bases
CCTACGACGTGCCCGAAGCCATTGCCGTGCAGGCCAGCGCCGGCCTGCCGGCCTACCTGGACTGGGTGCGTGCCGAAACC
CGCAAGGAATCCTGACGTTC

Downstream 100 bases:

>100_bases
GGCCCAGCCAATCAGTACTGACTGCCGCGGCGCGCTGGCATGGCGCGTTCCGGTGACCGGCTGAGGGCAATGGCGTCATT
ACGTGTGAGCGGCCGCAAGA

Product: c-type cytochrome biogenesis protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 768; Mature: 768

Protein sequence:

>768_residues
MKSLSRWIARCAVLVAPLFVALPLLLTAPAAQAVTEADLLPVDQAFALSAKADGRDRIALTWKIAPGYYLYRHRISVKSG
QGFTAGALDLPEGESKHDEFFGQVQTYRTALQASLAGKAAPGQRSAILQVQYQGCADAGVCYPPQRRELRVDLPDAPTTA
PPRESLGALVPRGPSGARLFGAPGQTAGVDALPLPADQAFNFEAIVGDGNSLLLRFTPAPGYYLYRDRTSLSLEGTSDIR
TGLPRWPQGRTHRDEHFGDVVVYFDQAEVTLPLLRDRPDPARVTLVATFQGCQSDGICYPPMTRRVRLDLPAGTVSPHNQ
ATATPLLISPLSAGEVAAERAAPGPPADAAPGPDATAGNPERSRPPHLERNLLAILLLALAGGLVLNLMPCVLPILSLKV
LGLAHSGESRNHARSHAIWYSLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFTLGSN
LGGIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPAPLAMLVFLTLGLGLALPFLLIGFIPSLARRLP
TPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALMLVGATLLALGLWWFERSRWNSHRLGMGLAAAMLVLAIVPV
VAVTRLSLPRATATEGSVTYTPELLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSTDFRDALRRVDAVYMKGDWTNVD
PKISAFLDQHQAVGVPLYVVYGPGAPPAVLPTVLTGAITEDALLRAAR

Sequences:

>Translated_768_residues
MKSLSRWIARCAVLVAPLFVALPLLLTAPAAQAVTEADLLPVDQAFALSAKADGRDRIALTWKIAPGYYLYRHRISVKSG
QGFTAGALDLPEGESKHDEFFGQVQTYRTALQASLAGKAAPGQRSAILQVQYQGCADAGVCYPPQRRELRVDLPDAPTTA
PPRESLGALVPRGPSGARLFGAPGQTAGVDALPLPADQAFNFEAIVGDGNSLLLRFTPAPGYYLYRDRTSLSLEGTSDIR
TGLPRWPQGRTHRDEHFGDVVVYFDQAEVTLPLLRDRPDPARVTLVATFQGCQSDGICYPPMTRRVRLDLPAGTVSPHNQ
ATATPLLISPLSAGEVAAERAAPGPPADAAPGPDATAGNPERSRPPHLERNLLAILLLALAGGLVLNLMPCVLPILSLKV
LGLAHSGESRNHARSHAIWYSLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFTLGSN
LGGIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPAPLAMLVFLTLGLGLALPFLLIGFIPSLARRLP
TPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALMLVGATLLALGLWWFERSRWNSHRLGMGLAAAMLVLAIVPV
VAVTRLSLPRATATEGSVTYTPELLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSTDFRDALRRVDAVYMKGDWTNVD
PKISAFLDQHQAVGVPLYVVYGPGAPPAVLPTVLTGAITEDALLRAAR
>Mature_768_residues
MKSLSRWIARCAVLVAPLFVALPLLLTAPAAQAVTEADLLPVDQAFALSAKADGRDRIALTWKIAPGYYLYRHRISVKSG
QGFTAGALDLPEGESKHDEFFGQVQTYRTALQASLAGKAAPGQRSAILQVQYQGCADAGVCYPPQRRELRVDLPDAPTTA
PPRESLGALVPRGPSGARLFGAPGQTAGVDALPLPADQAFNFEAIVGDGNSLLLRFTPAPGYYLYRDRTSLSLEGTSDIR
TGLPRWPQGRTHRDEHFGDVVVYFDQAEVTLPLLRDRPDPARVTLVATFQGCQSDGICYPPMTRRVRLDLPAGTVSPHNQ
ATATPLLISPLSAGEVAAERAAPGPPADAAPGPDATAGNPERSRPPHLERNLLAILLLALAGGLVLNLMPCVLPILSLKV
LGLAHSGESRNHARSHAIWYSLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFTLGSN
LGGIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPAPLAMLVFLTLGLGLALPFLLIGFIPSLARRLP
TPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALMLVGATLLALGLWWFERSRWNSHRLGMGLAAAMLVLAIVPV
VAVTRLSLPRATATEGSVTYTPELLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSTDFRDALRRVDAVYMKGDWTNVD
PKISAFLDQHQAVGVPLYVVYGPGAPPAVLPTVLTGAITEDALLRAAR

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=586, Percent_Identity=29.1808873720137, Blast_Score=149, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 81818; Mature: 81818

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLSRWIARCAVLVAPLFVALPLLLTAPAAQAVTEADLLPVDQAFALSAKADGRDRIAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHEEECCCCCCCEEEE
TWKIAPGYYLYRHRISVKSGQGFTAGALDLPEGESKHDEFFGQVQTYRTALQASLAGKAA
EEEECCCEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PGQRSAILQVQYQGCADAGVCYPPQRRELRVDLPDAPTTAPPRESLGALVPRGPSGARLF
CCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCEEE
GAPGQTAGVDALPLPADQAFNFEAIVGDGNSLLLRFTPAPGYYLYRDRTSLSLEGTSDIR
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCEEEEECCCEEEECCCHHHH
TGLPRWPQGRTHRDEHFGDVVVYFDQAEVTLPLLRDRPDPARVTLVATFQGCQSDGICYP
HCCCCCCCCCCCCCCCCCCEEEEECCCCEEEHHHHCCCCCCEEEEEEEECCCCCCCEECC
PMTRRVRLDLPAGTVSPHNQATATPLLISPLSAGEVAAERAAPGPPADAAPGPDATAGNP
CCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
ERSRPPHLERNLLAILLLALAGGLVLNLMPCVLPILSLKVLGLAHSGESRNHARSHAIWY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
SLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFTLGSN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCC
LGGIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPAPLAMLVFLTLGL
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GLALPFLLIGFIPSLARRLPTPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALM
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LVGATLLALGLWWFERSRWNSHRLGMGLAAAMLVLAIVPVVAVTRLSLPRATATEGSVTY
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
TPELLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSTDFRDALRRVDAVYMKGDWTNVD
CHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHEEEEECCCCCCC
PKISAFLDQHQAVGVPLYVVYGPGAPPAVLPTVLTGAITEDALLRAAR
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSLSRWIARCAVLVAPLFVALPLLLTAPAAQAVTEADLLPVDQAFALSAKADGRDRIAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHEEECCCCCCCEEEE
TWKIAPGYYLYRHRISVKSGQGFTAGALDLPEGESKHDEFFGQVQTYRTALQASLAGKAA
EEEECCCEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PGQRSAILQVQYQGCADAGVCYPPQRRELRVDLPDAPTTAPPRESLGALVPRGPSGARLF
CCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCEEE
GAPGQTAGVDALPLPADQAFNFEAIVGDGNSLLLRFTPAPGYYLYRDRTSLSLEGTSDIR
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCEEEEECCCEEEECCCHHHH
TGLPRWPQGRTHRDEHFGDVVVYFDQAEVTLPLLRDRPDPARVTLVATFQGCQSDGICYP
HCCCCCCCCCCCCCCCCCCEEEEECCCCEEEHHHHCCCCCCEEEEEEEECCCCCCCEECC
PMTRRVRLDLPAGTVSPHNQATATPLLISPLSAGEVAAERAAPGPPADAAPGPDATAGNP
CCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
ERSRPPHLERNLLAILLLALAGGLVLNLMPCVLPILSLKVLGLAHSGESRNHARSHAIWY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
SLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFTLGSN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCC
LGGIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPAPLAMLVFLTLGL
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GLALPFLLIGFIPSLARRLPTPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALM
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LVGATLLALGLWWFERSRWNSHRLGMGLAAAMLVLAIVPVVAVTRLSLPRATATEGSVTY
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
TPELLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSTDFRDALRRVDAVYMKGDWTNVD
CHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHEEEEECCCCCCC
PKISAFLDQHQAVGVPLYVVYGPGAPPAVLPTVLTGAITEDALLRAAR
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA