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The map label for this gene is aspC [H]

Identifier: 66766449

GI number: 66766449

Start: 117835

End: 119037

Strand: Reverse

Name: aspC [H]

Synonym: XC_0100

Alternate gene names: 66766449

Gene position: 119037-117835 (Counterclockwise)

Preceding gene: 66766455

Following gene: 66766448

Centisome position: 2.31

GC content: 67.33

Gene sequence:

>1203_bases
GTGTCCTTCTTTGCAAATGTAGAACAGGTTCCAGGCGACCCCATCCTGGGCCTGACCGAGGCCTACAACGCCGACAGCCG
CCCCAACAAGGTCAATCTGGGTGTTGGCATCTATTACGACGAAAACGGGCGCATCCCGCTGTTGCGTGCCGTGCAGAAGA
TCGAGCAGCAGCTCGCGCTGGATGCCAAACCGCGCGGCTACCTGCCCATCGACGGCCTGGCCGCCTACGACAAGGCCACC
CAGGAGCTGCTGTTCGGCGCCGAGTCGGCGCTGGTGGCCTCCGGCCGCGTGGCGACCTCGCAGACCGTTGGCGGCAGCGG
TGCGCTGCGCGTGGGCGCGGACCTGCTCAAGAAGCTGCTGCCCACCTCCACCATCGCCATCAGCAACCCCAGCTGGGAAA
ACCACCGCGCGGTGTTCGGCGCGGCCGGCTTCGAGGTGGTGGATTACACCTATTTCGATGCCGCCAGCCACGGGCTGAAC
TTCGACGGCATGCTGGCCGACCTGGCCAAGCTGGAGCCGGGCACGGTGGTGCTGCTGCATGCCTGCTGCCACAACCCCAC
CGGTGCCGACCTCAGCCGCGAGCAGTGGAAGCAGCTGGCCGGCCTGTTGAAAGAACGCAACCTGTTCCCGTTCGTGGACA
TCGCCTACCAGGGCTTCGACAAGGGCATCGAGGCCGATGCGTACGCGGTGCGCCTGCTGGCGGCCGAAGGCATCGACACC
TACGTGGTGGCGAGCTCGTACTCCAAGTCGTTCTCGCTGTATGGCGAGCGCGTGGGCGCGCTGTCGGTGGTCTCGGCCAC
GGCCGCCGAAGCCAAGGCGGTGCAGTCGCAGGTCAAGCGCATCATCCGCACGATCTACTCCAGCCCGTCCACGCACGGCG
CCGCCCTGGTGGCCGGCGTGCTGACCAGCCCGGAGCTGCGCGATGTGTGGGAGCAGGAACTCACCGAAATGCGCGAGCGC
ATCCACGCGTTGCGTGCCGGCCTGGTCGCCAAGCTGGCCGCGCTGGGCGCACCGGAGTTCGAGTTCATCCAGCGCCAGGC
CGGCATGTTTTCGTACTCGGGCCTGACCAAGTCGCAGGTGGACCGCCTGCGTGACGAGTTCGCGATCTATGCGGTCGGCA
CCGGCCGCATCTGCGTGGCCGCGCTGAGCCAGCGCAATCTGGACTACGTGGCCCAGGCCGTGGCCACGGTCAGCCGCGGC
TGA

Upstream 100 bases:

>100_bases
GCTACCCCGCGCCGTGCCCTGTTAGGATGAGGCGGTTTGGCCGTGCCGCGGCCCGACGCCCGGCAGTATCCCCACCTTCC
GTCCTCCAGCGAGTCATGCC

Downstream 100 bases:

>100_bases
TCCTGCGCCGCAGCTTGCGCGATGAAGAGCCGGGAGCGCTGACGCCTCCCGGCTTTTTTGTGGGCGACGCGCGCTGCGAT
AGGCGCGCAAAGATGCAAAG

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSFFANVEQVPGDPILGLTEAYNADSRPNKVNLGVGIYYDENGRIPLLRAVQKIEQQLALDAKPRGYLPIDGLAAYDKAT
QELLFGAESALVASGRVATSQTVGGSGALRVGADLLKKLLPTSTIAISNPSWENHRAVFGAAGFEVVDYTYFDAASHGLN
FDGMLADLAKLEPGTVVLLHACCHNPTGADLSREQWKQLAGLLKERNLFPFVDIAYQGFDKGIEADAYAVRLLAAEGIDT
YVVASSYSKSFSLYGERVGALSVVSATAAEAKAVQSQVKRIIRTIYSSPSTHGAALVAGVLTSPELRDVWEQELTEMRER
IHALRAGLVAKLAALGAPEFEFIQRQAGMFSYSGLTKSQVDRLRDEFAIYAVGTGRICVAALSQRNLDYVAQAVATVSRG

Sequences:

>Translated_400_residues
MSFFANVEQVPGDPILGLTEAYNADSRPNKVNLGVGIYYDENGRIPLLRAVQKIEQQLALDAKPRGYLPIDGLAAYDKAT
QELLFGAESALVASGRVATSQTVGGSGALRVGADLLKKLLPTSTIAISNPSWENHRAVFGAAGFEVVDYTYFDAASHGLN
FDGMLADLAKLEPGTVVLLHACCHNPTGADLSREQWKQLAGLLKERNLFPFVDIAYQGFDKGIEADAYAVRLLAAEGIDT
YVVASSYSKSFSLYGERVGALSVVSATAAEAKAVQSQVKRIIRTIYSSPSTHGAALVAGVLTSPELRDVWEQELTEMRER
IHALRAGLVAKLAALGAPEFEFIQRQAGMFSYSGLTKSQVDRLRDEFAIYAVGTGRICVAALSQRNLDYVAQAVATVSRG
>Mature_399_residues
SFFANVEQVPGDPILGLTEAYNADSRPNKVNLGVGIYYDENGRIPLLRAVQKIEQQLALDAKPRGYLPIDGLAAYDKATQ
ELLFGAESALVASGRVATSQTVGGSGALRVGADLLKKLLPTSTIAISNPSWENHRAVFGAAGFEVVDYTYFDAASHGLNF
DGMLADLAKLEPGTVVLLHACCHNPTGADLSREQWKQLAGLLKERNLFPFVDIAYQGFDKGIEADAYAVRLLAAEGIDTY
VVASSYSKSFSLYGERVGALSVVSATAAEAKAVQSQVKRIIRTIYSSPSTHGAALVAGVLTSPELRDVWEQELTEMRERI
HALRAGLVAKLAALGAPEFEFIQRQAGMFSYSGLTKSQVDRLRDEFAIYAVGTGRICVAALSQRNLDYVAQAVATVSRG

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=400, Percent_Identity=44, Blast_Score=349, Evalue=3e-96,
Organism=Homo sapiens, GI4504067, Length=402, Percent_Identity=42.7860696517413, Blast_Score=317, Evalue=9e-87,
Organism=Homo sapiens, GI117414139, Length=381, Percent_Identity=28.8713910761155, Blast_Score=172, Evalue=6e-43,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=48.7373737373737, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1790488, Length=400, Percent_Identity=49.75, Blast_Score=389, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71981858, Length=402, Percent_Identity=41.044776119403, Blast_Score=341, Evalue=5e-94,
Organism=Caenorhabditis elegans, GI25147133, Length=400, Percent_Identity=41.75, Blast_Score=330, Evalue=5e-91,
Organism=Caenorhabditis elegans, GI17569539, Length=403, Percent_Identity=40.4466501240695, Blast_Score=307, Evalue=7e-84,
Organism=Caenorhabditis elegans, GI17569537, Length=404, Percent_Identity=32.4257425742574, Blast_Score=214, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=42.2535211267606, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17550384, Length=271, Percent_Identity=37.2693726937269, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6323055, Length=408, Percent_Identity=36.7647058823529, Blast_Score=285, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6322743, Length=438, Percent_Identity=32.8767123287671, Blast_Score=240, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24654046, Length=404, Percent_Identity=43.0693069306931, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI19922362, Length=398, Percent_Identity=43.4673366834171, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24580972, Length=401, Percent_Identity=39.4014962593516, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24580970, Length=401, Percent_Identity=39.4014962593516, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI19920542, Length=392, Percent_Identity=39.7959183673469, Blast_Score=307, Evalue=9e-84,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42984; Mature: 42853

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFANVEQVPGDPILGLTEAYNADSRPNKVNLGVGIYYDENGRIPLLRAVQKIEQQLAL
CCCCCCHHHCCCCCCCCCHHHCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHC
DAKPRGYLPIDGLAAYDKATQELLFGAESALVASGRVATSQTVGGSGALRVGADLLKKLL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHC
PTSTIAISNPSWENHRAVFGAAGFEVVDYTYFDAASHGLNFDGMLADLAKLEPGTVVLLH
CCCEEEECCCCCCCCCEEEECCCCEEEEEEEHHHHHCCCCCCHHHHHHHHCCCCCEEEEE
ACCHNPTGADLSREQWKQLAGLLKERNLFPFVDIAYQGFDKGIEADAYAVRLLAAEGIDT
EHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCE
YVVASSYSKSFSLYGERVGALSVVSATAAEAKAVQSQVKRIIRTIYSSPSTHGAALVAGV
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LTSPELRDVWEQELTEMRERIHALRAGLVAKLAALGAPEFEFIQRQAGMFSYSGLTKSQV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHH
DRLRDEFAIYAVGTGRICVAALSQRNLDYVAQAVATVSRG
HHHHHCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFFANVEQVPGDPILGLTEAYNADSRPNKVNLGVGIYYDENGRIPLLRAVQKIEQQLAL
CCCCCHHHCCCCCCCCCHHHCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHC
DAKPRGYLPIDGLAAYDKATQELLFGAESALVASGRVATSQTVGGSGALRVGADLLKKLL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHC
PTSTIAISNPSWENHRAVFGAAGFEVVDYTYFDAASHGLNFDGMLADLAKLEPGTVVLLH
CCCEEEECCCCCCCCCEEEECCCCEEEEEEEHHHHHCCCCCCHHHHHHHHCCCCCEEEEE
ACCHNPTGADLSREQWKQLAGLLKERNLFPFVDIAYQGFDKGIEADAYAVRLLAAEGIDT
EHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCE
YVVASSYSKSFSLYGERVGALSVVSATAAEAKAVQSQVKRIIRTIYSSPSTHGAALVAGV
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LTSPELRDVWEQELTEMRERIHALRAGLVAKLAALGAPEFEFIQRQAGMFSYSGLTKSQV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHH
DRLRDEFAIYAVGTGRICVAALSQRNLDYVAQAVATVSRG
HHHHHCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]