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The map label for this gene is glsA [H]

Identifier: 66045532

GI number: 66045532

Start: 2663686

End: 2664594

Strand: Direct

Name: glsA [H]

Synonym: Psyr_2292

Alternate gene names: 66045532

Gene position: 2663686-2664594 (Clockwise)

Preceding gene: 66045531

Following gene: 66045533

Centisome position: 43.71

GC content: 61.06

Gene sequence:

>909_bases
ATGCAAGACCTGCTGAACGAAATCCTCGACGAAGTAAGACCCTTGCTTGGTCAGGGCAAGGTTGCCGATTACATCCCGGC
ACTGGGCGAGGTCCGGCCTGATCAACTGGGCATCGCGGTGTACGGCAACGATGGCCAGGTGTTCAGCGCCGGCGACGCCG
AAACGGCGTTTTCGATACAGAGCATTTCCAAGGTGTTCAGCCTGGTGCAAGCCATCAATCACTCGGGCGAGGAGATCTGG
CAGCGCCTCGGGCACGAGCCTTCCGGCCAGCCGTTCAACTCGCTGGTGCAGCTCGAATTCGAGCAGGGCAGGCCACGCAA
CCCGTTCATCAATGCCGGTGCGCTGGTGATCTGCGACATCAATCAGGCGCGGTTTGCAGCACCGTCGCTGTCGATGCGCG
ACTTCGTTCGACGCCTGTGCGGCAATCGGGCGATCACTTCCGACTCCAAAGTCGCCGACTCCGAATACCAGCACCGTTCG
CGCAATGCCGCGGCGGCCTATCTGATGAAGTCCTTCGACAATTTCCACGGCGATGTGGAAGACGTGCTGCGCAGCTACTT
CCACCATTGTGCGCTGAGCATGAACTGCATCGATCTGGCCAAGGCATTCGGCTTCCTGGCGCATCAGGGCTTTTGCGCGC
ACAGCGGCGAGCAGGTCCTCACTGCGCGTCAGGCCACCCAGGTCAACTCGATCATGGCCACCAGCGGCTTGTACGACGAG
GCCGGCAACTTCGCTTATCGCGTAGGCCTGCCGGGCAAGAGCGGGGTTGGCGGTGGTATCGTTGCGATCGTGCCCGAGCG
TGCTTCAGTCTGTGTGTGGTCCCCGGAGTTGAACGCAGCGGGCAATTCCCTTGTCGGTATGGCTGCGCTGGAAAAACTCA
GCGCGAGGGTCGACTGGTCGGTCTTTTGA

Upstream 100 bases:

>100_bases
GAGCGTAATGACACCGACTACAGGACCTGAGCCTGCAACGCAGTGATGCGAGGCGCTTGAGGTTGGTGTAGTGTGCGCAG
CCAAAACAAGGGGCGCACAC

Downstream 100 bases:

>100_bases
GGTAAAAAGCCTTCTGAAGTGAACCGCGCGTCGAAGCGCGAACCAGACAGGAGTCATGGATTGAATAGAAGGCTATGCAA
ATCGCTCATGCTGAGCGTCG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MQDLLNEILDEVRPLLGQGKVADYIPALGEVRPDQLGIAVYGNDGQVFSAGDAETAFSIQSISKVFSLVQAINHSGEEIW
QRLGHEPSGQPFNSLVQLEFEQGRPRNPFINAGALVICDINQARFAAPSLSMRDFVRRLCGNRAITSDSKVADSEYQHRS
RNAAAAYLMKSFDNFHGDVEDVLRSYFHHCALSMNCIDLAKAFGFLAHQGFCAHSGEQVLTARQATQVNSIMATSGLYDE
AGNFAYRVGLPGKSGVGGGIVAIVPERASVCVWSPELNAAGNSLVGMAALEKLSARVDWSVF

Sequences:

>Translated_302_residues
MQDLLNEILDEVRPLLGQGKVADYIPALGEVRPDQLGIAVYGNDGQVFSAGDAETAFSIQSISKVFSLVQAINHSGEEIW
QRLGHEPSGQPFNSLVQLEFEQGRPRNPFINAGALVICDINQARFAAPSLSMRDFVRRLCGNRAITSDSKVADSEYQHRS
RNAAAAYLMKSFDNFHGDVEDVLRSYFHHCALSMNCIDLAKAFGFLAHQGFCAHSGEQVLTARQATQVNSIMATSGLYDE
AGNFAYRVGLPGKSGVGGGIVAIVPERASVCVWSPELNAAGNSLVGMAALEKLSARVDWSVF
>Mature_302_residues
MQDLLNEILDEVRPLLGQGKVADYIPALGEVRPDQLGIAVYGNDGQVFSAGDAETAFSIQSISKVFSLVQAINHSGEEIW
QRLGHEPSGQPFNSLVQLEFEQGRPRNPFINAGALVICDINQARFAAPSLSMRDFVRRLCGNRAITSDSKVADSEYQHRS
RNAAAAYLMKSFDNFHGDVEDVLRSYFHHCALSMNCIDLAKAFGFLAHQGFCAHSGEQVLTARQATQVNSIMATSGLYDE
AGNFAYRVGLPGKSGVGGGIVAIVPERASVCVWSPELNAAGNSLVGMAALEKLSARVDWSVF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=274, Percent_Identity=37.5912408759124, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI20336214, Length=297, Percent_Identity=33.6700336700337, Blast_Score=150, Evalue=1e-36,
Organism=Escherichia coli, GI1787804, Length=300, Percent_Identity=62, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1786693, Length=290, Percent_Identity=36.551724137931, Blast_Score=171, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17507019, Length=302, Percent_Identity=34.4370860927152, Blast_Score=168, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI193204073, Length=300, Percent_Identity=33.6666666666667, Blast_Score=162, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI193204075, Length=302, Percent_Identity=33.4437086092715, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17532727, Length=306, Percent_Identity=33.0065359477124, Blast_Score=161, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=35.0877192982456, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=35.0877192982456, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=35.0877192982456, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=35.0877192982456, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=35.0877192982456, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=35.0877192982456, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=35.0877192982456, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=35.0877192982456, Blast_Score=173, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 32683; Mature: 32683

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLLNEILDEVRPLLGQGKVADYIPALGEVRPDQLGIAVYGNDGQVFSAGDAETAFSIQ
CHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCCHHHHHHH
SISKVFSLVQAINHSGEEIWQRLGHEPSGQPFNSLVQLEFEQGRPRNPFINAGALVICDI
HHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHEEEEECCCCCCCCCCCCCEEEEEEC
NQARFAAPSLSMRDFVRRLCGNRAITSDSKVADSEYQHRSRNAAAAYLMKSFDNFHGDVE
CHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DVLRSYFHHCALSMNCIDLAKAFGFLAHQGFCAHSGEQVLTARQATQVNSIMATSGLYDE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
AGNFAYRVGLPGKSGVGGGIVAIVPERASVCVWSPELNAAGNSLVGMAALEKLSARVDWS
CCCEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCC
VF
CC
>Mature Secondary Structure
MQDLLNEILDEVRPLLGQGKVADYIPALGEVRPDQLGIAVYGNDGQVFSAGDAETAFSIQ
CHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCCHHHHHHH
SISKVFSLVQAINHSGEEIWQRLGHEPSGQPFNSLVQLEFEQGRPRNPFINAGALVICDI
HHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHEEEEECCCCCCCCCCCCCEEEEEEC
NQARFAAPSLSMRDFVRRLCGNRAITSDSKVADSEYQHRSRNAAAAYLMKSFDNFHGDVE
CHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DVLRSYFHHCALSMNCIDLAKAFGFLAHQGFCAHSGEQVLTARQATQVNSIMATSGLYDE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
AGNFAYRVGLPGKSGVGGGIVAIVPERASVCVWSPELNAAGNSLVGMAALEKLSARVDWS
CCCEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCC
VF
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA