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The map label for this gene is mcp4 [H]

Identifier: 66045481

GI number: 66045481

Start: 2605380

End: 2607176

Strand: Direct

Name: mcp4 [H]

Synonym: Psyr_2241

Alternate gene names: 66045481

Gene position: 2605380-2607176 (Clockwise)

Preceding gene: 66045480

Following gene: 66045482

Centisome position: 42.76

GC content: 57.6

Gene sequence:

>1797_bases
ATGCAGACGTTAAAGGCTTTGTACGAGTCAGTTGAAAAGCAGTTTTTCAACACGCTGACCAAGAAGCTATCAAGCCTTTT
CCTGCTGGTCCTGGTCAGCGCCTTGCTGTATTGGGTGGCGCTGAATATTCGTTCCGACATCATGCTGCAATTGCGCGGCA
CACAAACGGACCCGGCCGCGCTGGGCGTGATCCAGAGTCAGCTCGATCTGCTGAGCAATGCGATTTTGCTGAGCACGCTG
TTCACGCTGGTCATGGTCAGCTTCATGGTCTGGTATTTCCGCCACCTGATCGTGCGCCCGGTGATGTCCATGACCCGTGC
GCTCGAAGAGGTCGCCAGCGGTGAAGGTGATCTGTCGAGGGATCTGCCGTTGCTCACTCACGATGAAATTCGCGGGCTGG
CCAGTACCTGCAATCTCTTTCTGGCCAAACAGCGTGAGATCATCAGCAGCATTCAGGGGCTGACGGTACAGATTGCCGTC
GAGTCGGCGCGTTCGCTGAAGAACATCAGTGATTCCAGCGACAGCGCGACCGATCAGGCCCGCTTCGCCAGAGAAGTGAT
GGACCAGAGCAACATGGCAGTGGGCAGCATCGAGGATGTCTCGCAGCAGACTCAGGGCATTTCCAGCACCACCGCGCAGA
ACCTGAGCATGGCGCGCGACTCTTACGCCGAATTGCTGGAAGTGACCGGAAACATCAGCCAGATATCCAGCAGCCTGAAT
GAGTTCGGTGGGCTGGTCTCCGGCTTGAATGAGCGTTCATCAAGCATCAAGTCGATTGTCGGGCTTATTCAGCAGATTTC
TTCGCAAACCAACCTGTTGGCGCTCAATGCGGCCATCGAAGCGGCGCGGGCGGGGGAGAGTGGTCGAGGTTTCGCGGTGG
TGGCCGACGAAGTACGCACGCTGGCGCAAAACGTCAGTAAAGCCACTGACGACATCTCGCGCAACATCGACGCCATGCTT
CAGGAAGTCAGCTCCACACACGAACAGACCATTCAGATCAGCCAAAGCGCCCGCGAAACCCAGCTGGTGGTGGAGCGTGC
GTCCGGCCATTTCGAAAGCATGATCGGCGATTTCGAGTCGACCAACGACAAGCTCGCCGACATCGCGGCGCACATTCAGC
AGTTTGCCTCTACAAACACGGGGATCAATGAACGGGTAACGCGGATTTATTCCGATAGCCAGGCCATCGACCAGCGCATG
CAGCACTCCGCGACGGCCACCCGGGATCTGTCCAGTGTGGCCGAGCAGGTGCAGGCGTTGCTGGGGCGATTTGTGCTTGG
GCATGGCGAACTGGATGCGGCGATTACTCGCGCCAGTCAGTGCCGTGACATTCTGCAAGTCCGCCTGGCCGAGCTGCACA
AGCAGGGTGTCAATCTGTTCGATCAGAGTTACAAGCTGATTCCGGGCACAGACCCCAAACAATACACGACCGGTTACACC
GAGCGTTTTGCGCAAATCTGCCAGGAAGAATGCGACAAGCTGACCAAGGGCACACGCGGCGGCAAGGTCACCTTCATCGT
CGACAGCAAAGGCTATTGCCCGGTCAATAACAGCTGGGTATCGCAAAAACCTACCGGCAATCGCGAAGTCGACCTGCCGG
TGTGCCGCAACAAACGCATGTTCTCCGACCCGATCGGCCTGCGTGCCGCAGGCAACAAGCAGCGTTTTCTGTTGCAGACT
TACTTGCGCGATACCGGCGAGATCATGACCGAAATCGATGTGCCGTTCTTTTTCGAGGGGCGCCACTGGGGCAACTTGCG
GATGGGCTTCGATGCCGCGCTGCTGCTGGGGAAATAA

Upstream 100 bases:

>100_bases
AAGTTTTTCCGCCTGCGCTGAAGGCGAACGCATTAAAGCTTTGGTAGCGACAGACGTTAACCATCGCACCGGAATCACCC
TTGTACCCAGGAGCAGCAAA

Downstream 100 bases:

>100_bases
GCCGGGGCGCGACGTGCGCGCCCGATGCTCGATGCCGACCCACAGTAACATCGCCTAACCCGTTTCATGTACCCATGGCA
GAACGCATGCAGGCTGGCCT

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MQTLKALYESVEKQFFNTLTKKLSSLFLLVLVSALLYWVALNIRSDIMLQLRGTQTDPAALGVIQSQLDLLSNAILLSTL
FTLVMVSFMVWYFRHLIVRPVMSMTRALEEVASGEGDLSRDLPLLTHDEIRGLASTCNLFLAKQREIISSIQGLTVQIAV
ESARSLKNISDSSDSATDQARFAREVMDQSNMAVGSIEDVSQQTQGISSTTAQNLSMARDSYAELLEVTGNISQISSSLN
EFGGLVSGLNERSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAML
QEVSSTHEQTIQISQSARETQLVVERASGHFESMIGDFESTNDKLADIAAHIQQFASTNTGINERVTRIYSDSQAIDQRM
QHSATATRDLSSVAEQVQALLGRFVLGHGELDAAITRASQCRDILQVRLAELHKQGVNLFDQSYKLIPGTDPKQYTTGYT
ERFAQICQEECDKLTKGTRGGKVTFIVDSKGYCPVNNSWVSQKPTGNREVDLPVCRNKRMFSDPIGLRAAGNKQRFLLQT
YLRDTGEIMTEIDVPFFFEGRHWGNLRMGFDAALLLGK

Sequences:

>Translated_598_residues
MQTLKALYESVEKQFFNTLTKKLSSLFLLVLVSALLYWVALNIRSDIMLQLRGTQTDPAALGVIQSQLDLLSNAILLSTL
FTLVMVSFMVWYFRHLIVRPVMSMTRALEEVASGEGDLSRDLPLLTHDEIRGLASTCNLFLAKQREIISSIQGLTVQIAV
ESARSLKNISDSSDSATDQARFAREVMDQSNMAVGSIEDVSQQTQGISSTTAQNLSMARDSYAELLEVTGNISQISSSLN
EFGGLVSGLNERSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAML
QEVSSTHEQTIQISQSARETQLVVERASGHFESMIGDFESTNDKLADIAAHIQQFASTNTGINERVTRIYSDSQAIDQRM
QHSATATRDLSSVAEQVQALLGRFVLGHGELDAAITRASQCRDILQVRLAELHKQGVNLFDQSYKLIPGTDPKQYTTGYT
ERFAQICQEECDKLTKGTRGGKVTFIVDSKGYCPVNNSWVSQKPTGNREVDLPVCRNKRMFSDPIGLRAAGNKQRFLLQT
YLRDTGEIMTEIDVPFFFEGRHWGNLRMGFDAALLLGK
>Mature_598_residues
MQTLKALYESVEKQFFNTLTKKLSSLFLLVLVSALLYWVALNIRSDIMLQLRGTQTDPAALGVIQSQLDLLSNAILLSTL
FTLVMVSFMVWYFRHLIVRPVMSMTRALEEVASGEGDLSRDLPLLTHDEIRGLASTCNLFLAKQREIISSIQGLTVQIAV
ESARSLKNISDSSDSATDQARFAREVMDQSNMAVGSIEDVSQQTQGISSTTAQNLSMARDSYAELLEVTGNISQISSSLN
EFGGLVSGLNERSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEVRTLAQNVSKATDDISRNIDAML
QEVSSTHEQTIQISQSARETQLVVERASGHFESMIGDFESTNDKLADIAAHIQQFASTNTGINERVTRIYSDSQAIDQRM
QHSATATRDLSSVAEQVQALLGRFVLGHGELDAAITRASQCRDILQVRLAELHKQGVNLFDQSYKLIPGTDPKQYTTGYT
ERFAQICQEECDKLTKGTRGGKVTFIVDSKGYCPVNNSWVSQKPTGNREVDLPVCRNKRMFSDPIGLRAAGNKQRFLLQT
YLRDTGEIMTEIDVPFFFEGRHWGNLRMGFDAALLLGK

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=376, Percent_Identity=24.7340425531915, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI2367378, Length=295, Percent_Identity=25.7627118644068, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787690, Length=245, Percent_Identity=31.0204081632653, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789453, Length=244, Percent_Identity=30.327868852459, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788195, Length=279, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 65879; Mature: 65879

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLKALYESVEKQFFNTLTKKLSSLFLLVLVSALLYWVALNIRSDIMLQLRGTQTDPAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
LGVIQSQLDLLSNAILLSTLFTLVMVSFMVWYFRHLIVRPVMSMTRALEEVASGEGDLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DLPLLTHDEIRGLASTCNLFLAKQREIISSIQGLTVQIAVESARSLKNISDSSDSATDQA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCCCCHHHHH
RFAREVMDQSNMAVGSIEDVSQQTQGISSTTAQNLSMARDSYAELLEVTGNISQISSSLN
HHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EFGGLVSGLNERSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEVRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHH
LAQNVSKATDDISRNIDAMLQEVSSTHEQTIQISQSARETQLVVERASGHFESMIGDFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHC
TNDKLADIAAHIQQFASTNTGINERVTRIYSDSQAIDQRMQHSATATRDLSSVAEQVQAL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGRFVLGHGELDAAITRASQCRDILQVRLAELHKQGVNLFDQSYKLIPGTDPKQYTTGYT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHCCCHH
ERFAQICQEECDKLTKGTRGGKVTFIVDSKGYCPVNNSWVSQKPTGNREVDLPVCRNKRM
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
FSDPIGLRAAGNKQRFLLQTYLRDTGEIMTEIDVPFFFEGRHWGNLRMGFDAALLLGK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEECCHHHHHCCC
>Mature Secondary Structure
MQTLKALYESVEKQFFNTLTKKLSSLFLLVLVSALLYWVALNIRSDIMLQLRGTQTDPAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
LGVIQSQLDLLSNAILLSTLFTLVMVSFMVWYFRHLIVRPVMSMTRALEEVASGEGDLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DLPLLTHDEIRGLASTCNLFLAKQREIISSIQGLTVQIAVESARSLKNISDSSDSATDQA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCCCCHHHHH
RFAREVMDQSNMAVGSIEDVSQQTQGISSTTAQNLSMARDSYAELLEVTGNISQISSSLN
HHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EFGGLVSGLNERSSSIKSIVGLIQQISSQTNLLALNAAIEAARAGESGRGFAVVADEVRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHH
LAQNVSKATDDISRNIDAMLQEVSSTHEQTIQISQSARETQLVVERASGHFESMIGDFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHC
TNDKLADIAAHIQQFASTNTGINERVTRIYSDSQAIDQRMQHSATATRDLSSVAEQVQAL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGRFVLGHGELDAAITRASQCRDILQVRLAELHKQGVNLFDQSYKLIPGTDPKQYTTGYT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHCCCHH
ERFAQICQEECDKLTKGTRGGKVTFIVDSKGYCPVNNSWVSQKPTGNREVDLPVCRNKRM
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
FSDPIGLRAAGNKQRFLLQTYLRDTGEIMTEIDVPFFFEGRHWGNLRMGFDAALLLGK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]