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The map label for this gene is ppsA [H]

Identifier: 66045330

GI number: 66045330

Start: 2437628

End: 2440003

Strand: Direct

Name: ppsA [H]

Synonym: Psyr_2090

Alternate gene names: 66045330

Gene position: 2437628-2440003 (Clockwise)

Preceding gene: 66045328

Following gene: 66045331

Centisome position: 40.0

GC content: 61.66

Gene sequence:

>2376_bases
TTGGTAGAGTACGTAGTTTCCCTCGATAAGCTCGGCGTCCATGATGTAGAGCACGTGGGGGGCAAAAACTCGTCCCTCGG
CGAGATGATCAGCAACCTCGCAGGTGCTGGTGTTTCGGTGCCCGGCGGCTTCGCGACTACCGCCCAGGCTTACCGTGACT
TTCTCGAGCTCAGCGGCCTGAACGAGCAGATCCATGCGGCGCTGGACGCCCTTGATGTCGATGACGTCAACGCGCTGGCC
CGCACGGGTGCGCAGATTCGTCAGTGGATCATGGAAGCCGAGTTCCCCGAGCAGCTCAACGCCCAGATCCGTACTGCGTT
TGCCGAGCTCTCTGCCGGTAACCCGAACCTGGCCGTGGCCGTGCGCTCCTCCGCAACGGCCGAAGATTTGCCGGATGCGT
CGTTCGCCGGCCAGCAGGAGACCTTCCTGAACATCCGCGGCGTCGAGAACGTGATCCGCGCGGCCAAGGAAGTCTTCGCT
TCACTGTTCAACGACCGTGCGATTTCCTACCGCGTACACCAGGGCTTCGACCACAAGCTGGTCGCGCTGTCTGCGGGTGT
GCAGCGCATGGTGCGCTCCGAAACCGGTACGGCCGGTGTCATGTTCACCCTCGACACCGAGTCCGGTTTCCGCGATGTGG
TGTTCATCACCGGTGCCTACGGTCTGGGCGAGACGGTCGTGCAGGGCGCCGTCAACCCCGACGAATTCTACGTGCACAAG
GACACGCTGGCGGCTGGTCGCCCGGCGATCCTGCGTCGCAATCTGGGCAGCAAGGCGATCAAGATGATTTACGGCGAAGA
AGCCAAGGCCGGTCGTTCGGTCAAGGTGATCGACGTCGAGCCTGCCGATCGTGCACGTTTCTGTCTGAGCGATGCCGAAG
TGTCCGAACTGGCCAAACAGGCGATGATCATCGAGAAGCACTACAAGTGCCCGATGGACATCGAGTGGGCCAAGGACGGT
GACGACGGCAAGCTGTACATCGTCCAGGCACGTCCGGAAACGGTGAAGAGCCGTGCGTCGGCTAACGTCATGGAACGCTA
TCTGCTCAAGGAGACCGGCAAGGTGCTGGTCGAAGGCCGTGCCATCGGTCAGCGCATCGGCGCGGGCAAGGTGCGTATCA
TCAAGGACGTGTCCGAGATGGACAAGGTCCAGCCCGGTGACGTGCTGGTGTCGGACATGACCGACCCGGACTGGGAACCG
GTGATGAAGCGTGCCAGCGCAATCGTCACCAACCGTGGCGGTCGTACCTGCCACGCCGCGATCATCGCCCGTGAGCTGGG
CATCCCGGCAGTGGTCGGCTGCGGCAACGCCACGCATACCCTTCAGGATGGCCAGGGTGTCACGGTTTCCTGTGCAGAGG
GCGACACCGGTTATATCTTCGAAGGCGAGCTGGGCTTCGACATCAAGACCAACTCGGTCGATGCCATGCCTGATCTGCCG
TTCAAGATCATGATGAACGTCGGCAACCCGGACCGTGCCTTTGATTTCGCCCAGTTGCCCAATGCCGGTGTCGGCCTGGC
GCGTCTGGAGTTCATTATCAACCGCATGATCGGCGTGCACCCCAAGGCGCTGCTCAACTATTCGGTGTTGCCACCGGAAA
TCAAGGAAAGCGTCGACAAGCGCATCGCCGGTTACGACGATCCGGTCGGTTTCTATGTCGACAAGCTGGTCGAGGGCATC
AGCACTCTGGCCGCCGCGTTCACGCCGAAAAAAGTCATCGTGCGCCTCTCGGACTTCAAGTCCAACGAGTACGCGAACCT
GATCGGCGGCAAGCTCTACGAGCCCGAAGAAGAAAACCCGATGCTGGGCTTCCGCGGTGCGTCGCGCTATATCAGCGAGA
ACTTCCGTGACTGCTTCGAGCTGGAGTGCCGTGCGCTCAAGCGTGTGCGCGAGGAGATGGGCCTGACCAACGTCGAGATC
ATGGTGCCGTTCGTCCGCACCCTGGGCGAGGCGAGCCAGGTGATCGATCTGCTGGCCGCCAACGGCCTGAAGCGTGGCGA
AAACGGCCTGCGCATCATCATGATGTGCGAGCTGCCGTCCAACGCGATTCTGGCGGAAGAGTTCCTCGAGTATTTCGACG
GCTTCTCCATCGGCTCCAACGACCTGACTCAGCTGACGCTCGGTCTCGACCGTGACTCCGGTGTGATCGCTCACCTGTTC
GACGAGCGTAACCCGGCGGTCAAGAAGCTGCTGTCCAACGCCATTCAGGCGTGCAACAAGGCCGGCAAGTACATCGGCAT
CTGCGGGCAGGGGCCTTCCGATCACCCGGATCTGGCGCGCTGGCTGATGGATCAGGGCATCGAGAGTGTCTCGCTCAACC
CTGATTCGGTACTGGAGACCTGGTTCTTCCTCGCCGAGGCACAGGCGCCTGTCTGA

Upstream 100 bases:

>100_bases
CGATCTGTACGTCCGGGCAGACACGCCTGAAGCCACACCGCATGTGGCGCAGGTGAATGAGCTTTTCCCAACAACAAACA
CAGTTAGTGGAGAGATCACC

Downstream 100 bases:

>100_bases
CAGGCGGTGGCTCGCCTGAGGCGCATTCCTCGCAACACCGGGCTGCCGTGTGACGCGAACGCGGCCTGAGCCGTCATGTG
GTTCAGGTGTTTGAATGAGG

Product: phosphoenolpyruvate synthase

Products: NA

Alternate protein names: PEP synthase; Pyruvate, water dikinase [H]

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MVEYVVSLDKLGVHDVEHVGGKNSSLGEMISNLAGAGVSVPGGFATTAQAYRDFLELSGLNEQIHAALDALDVDDVNALA
RTGAQIRQWIMEAEFPEQLNAQIRTAFAELSAGNPNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFA
SLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHK
DTLAAGRPAILRRNLGSKAIKMIYGEEAKAGRSVKVIDVEPADRARFCLSDAEVSELAKQAMIIEKHYKCPMDIEWAKDG
DDGKLYIVQARPETVKSRASANVMERYLLKETGKVLVEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEP
VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVSCAEGDTGYIFEGELGFDIKTNSVDAMPDLP
FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYSVLPPEIKESVDKRIAGYDDPVGFYVDKLVEGI
STLAAAFTPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISENFRDCFELECRALKRVREEMGLTNVEI
MVPFVRTLGEASQVIDLLAANGLKRGENGLRIIMMCELPSNAILAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGVIAHLF
DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLARWLMDQGIESVSLNPDSVLETWFFLAEAQAPV

Sequences:

>Translated_791_residues
MVEYVVSLDKLGVHDVEHVGGKNSSLGEMISNLAGAGVSVPGGFATTAQAYRDFLELSGLNEQIHAALDALDVDDVNALA
RTGAQIRQWIMEAEFPEQLNAQIRTAFAELSAGNPNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFA
SLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHK
DTLAAGRPAILRRNLGSKAIKMIYGEEAKAGRSVKVIDVEPADRARFCLSDAEVSELAKQAMIIEKHYKCPMDIEWAKDG
DDGKLYIVQARPETVKSRASANVMERYLLKETGKVLVEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEP
VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVSCAEGDTGYIFEGELGFDIKTNSVDAMPDLP
FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYSVLPPEIKESVDKRIAGYDDPVGFYVDKLVEGI
STLAAAFTPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISENFRDCFELECRALKRVREEMGLTNVEI
MVPFVRTLGEASQVIDLLAANGLKRGENGLRIIMMCELPSNAILAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGVIAHLF
DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLARWLMDQGIESVSLNPDSVLETWFFLAEAQAPV
>Mature_791_residues
MVEYVVSLDKLGVHDVEHVGGKNSSLGEMISNLAGAGVSVPGGFATTAQAYRDFLELSGLNEQIHAALDALDVDDVNALA
RTGAQIRQWIMEAEFPEQLNAQIRTAFAELSAGNPNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFA
SLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHK
DTLAAGRPAILRRNLGSKAIKMIYGEEAKAGRSVKVIDVEPADRARFCLSDAEVSELAKQAMIIEKHYKCPMDIEWAKDG
DDGKLYIVQARPETVKSRASANVMERYLLKETGKVLVEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEP
VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVSCAEGDTGYIFEGELGFDIKTNSVDAMPDLP
FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYSVLPPEIKESVDKRIAGYDDPVGFYVDKLVEGI
STLAAAFTPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISENFRDCFELECRALKRVREEMGLTNVEI
MVPFVRTLGEASQVIDLLAANGLKRGENGLRIIMMCELPSNAILAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGVIAHLF
DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLARWLMDQGIESVSLNPDSVLETWFFLAEAQAPV

Specific function: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=782, Percent_Identity=68.925831202046, Blast_Score=1144, Evalue=0.0,
Organism=Escherichia coli, GI1788756, Length=479, Percent_Identity=26.0960334029228, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788726, Length=191, Percent_Identity=31.413612565445, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI48994992, Length=190, Percent_Identity=33.1578947368421, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1789193, Length=403, Percent_Identity=25.8064516129032, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17564524, Length=329, Percent_Identity=25.8358662613982, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR006319
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.2 [H]

Molecular weight: Translated: 86083; Mature: 86083

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEYVVSLDKLGVHDVEHVGGKNSSLGEMISNLAGAGVSVPGGFATTAQAYRDFLELSGL
CCCEEEEHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
NEQIHAALDALDVDDVNALARTGAQIRQWIMEAEFPEQLNAQIRTAFAELSAGNPNLAVA
CHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEE
VRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFASLFNDRAISYRVHQGFDHKL
EECCCCHHCCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
VALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHK
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHCCCCCCCEEEEC
DTLAAGRPAILRRNLGSKAIKMIYGEEAKAGRSVKVIDVEPADRARFCLSDAEVSELAKQ
CHHCCCCHHHHHHCCCHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHCHHHHHHHHHH
AMIIEKHYKCPMDIEWAKDGDDGKLYIVQARPETVKSRASANVMERYLLKETGKVLVEGR
HHHHHHHCCCCCCCEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECH
AIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAA
HHHHHCCCCCEEEEHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHH
IIARELGIPAVVGCGNATHTLQDGQGVTVSCAEGDTGYIFEGELGFDIKTNSVDAMPDLP
HHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCEEECCCCCCCCCCC
FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYSVLPPEIKESVDK
CEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHH
RIAGYDDPVGFYVDKLVEGISTLAAAFTPKKVIVRLSDFKSNEYANLIGGKLYEPEEENP
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCHHHHHCCCCCCCCCCCC
MLGFRGASRYISENFRDCFELECRALKRVREEMGLTNVEIMVPFVRTLGEASQVIDLLAA
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHH
NGLKRGENGLRIIMMCELPSNAILAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGVIAHLF
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEC
DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLARWLMDQGIESVSLNPDSVLET
CCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCEECCCHHHHHHH
WFFLAEAQAPV
HHHHHHCCCCC
>Mature Secondary Structure
MVEYVVSLDKLGVHDVEHVGGKNSSLGEMISNLAGAGVSVPGGFATTAQAYRDFLELSGL
CCCEEEEHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
NEQIHAALDALDVDDVNALARTGAQIRQWIMEAEFPEQLNAQIRTAFAELSAGNPNLAVA
CHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEE
VRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFASLFNDRAISYRVHQGFDHKL
EECCCCHHCCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
VALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHK
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHCCCCCCCEEEEC
DTLAAGRPAILRRNLGSKAIKMIYGEEAKAGRSVKVIDVEPADRARFCLSDAEVSELAKQ
CHHCCCCHHHHHHCCCHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHCHHHHHHHHHH
AMIIEKHYKCPMDIEWAKDGDDGKLYIVQARPETVKSRASANVMERYLLKETGKVLVEGR
HHHHHHHCCCCCCCEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECH
AIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAA
HHHHHCCCCCEEEEHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHH
IIARELGIPAVVGCGNATHTLQDGQGVTVSCAEGDTGYIFEGELGFDIKTNSVDAMPDLP
HHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCEEECCCCCCCCCCC
FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYSVLPPEIKESVDK
CEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHH
RIAGYDDPVGFYVDKLVEGISTLAAAFTPKKVIVRLSDFKSNEYANLIGGKLYEPEEENP
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCHHHHHCCCCCCCCCCCC
MLGFRGASRYISENFRDCFELECRALKRVREEMGLTNVEIMVPFVRTLGEASQVIDLLAA
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHH
NGLKRGENGLRIIMMCELPSNAILAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGVIAHLF
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEC
DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLARWLMDQGIESVSLNPDSVLET
CCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCEECCCHHHHHHH
WFFLAEAQAPV
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1310524; 9097039; 9278503 [H]