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The map label for this gene is kdpE [H]

Identifier: 66045291

GI number: 66045291

Start: 2397247

End: 2397939

Strand: Direct

Name: kdpE [H]

Synonym: Psyr_2051

Alternate gene names: 66045291

Gene position: 2397247-2397939 (Clockwise)

Preceding gene: 66045290

Following gene: 66045292

Centisome position: 39.34

GC content: 63.06

Gene sequence:

>693_bases
TTGAGCCAGGCGACCACCATTCTGGTCATCGACGACGAGCCGCAGATTCGCAAGTTCCTGCGCATCAGTCTGGCGTCGCA
GGGTTACAAGGTGCTGGAAGCCGCCACGGGCGCCGAGGGTCTGACTCAGGCTGCCTTGAATAAACCGGATTTGCTGGTGC
TCGACCTTGGGCTGCCGGACATGGACGGTCAGCAGGTGCTGAGCGAGTTTCGCGAGTGGTCGGCGGTGCCGGTGCTGGTG
CTTTCGGTGCGCGCCAGTGAGGCACAGAAAGTCCAGGCGCTGGACGCCGGCGCCAACGACTACGTGACCAAGCCGTTTGG
CATTCAGGAGTTTCTGGCCCGGGTCAGGGCGCTGCTCAGGCAGGCGTCGGGCAGCGATAAGCCCGAATCTGCGCTTGAGT
TCGGGCCGCTCACCGTCGACCTCGCCTATCGGCGCGTGCTGCTCGACGGTCTCGAAGTGGCGCTGACCCGCAAGGAATAC
GCGGTGCTGGCGCAGTTGGCGCGGCATCCCGGGCGGGTCATTACCCAGCAGCAATTGCTCAAGGATATCTGGGGGCCTAC
GCACACCGAAGACAGTCACTATCTGCGTATCGTGGTGGGGCATTTGCGGCAGAAGCTGGCAGATGATCCGACCGCTCCGC
GGTTCATCCTCACCGAGCCTGGAATAGGGTATCGTCTGCTCGCTGATCACTAG

Upstream 100 bases:

>100_bases
GACGGCTTTCGGTCGAGGAGGGTATTGATGGGCTGGGTACGCGCATCACGCTGTTTCTGCCGCTGCAGGCGCAGCCGGAT
GTGGAACTGGAGGAGTCCGC

Downstream 100 bases:

>100_bases
ATGAAAAAAGCGAGCAGAGCCCCGTGCTGCGGCACTTTTACTGCCGCGCACCGTCAAAGCCGCACACTCCCTGTTCTCTC
TTGAGGTAACACCCGCATGA

Product: response regulator receiver:transcriptional regulatory protein, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSQATTILVIDDEPQIRKFLRISLASQGYKVLEAATGAEGLTQAALNKPDLLVLDLGLPDMDGQQVLSEFREWSAVPVLV
LSVRASEAQKVQALDAGANDYVTKPFGIQEFLARVRALLRQASGSDKPESALEFGPLTVDLAYRRVLLDGLEVALTRKEY
AVLAQLARHPGRVITQQQLLKDIWGPTHTEDSHYLRIVVGHLRQKLADDPTAPRFILTEPGIGYRLLADH

Sequences:

>Translated_230_residues
MSQATTILVIDDEPQIRKFLRISLASQGYKVLEAATGAEGLTQAALNKPDLLVLDLGLPDMDGQQVLSEFREWSAVPVLV
LSVRASEAQKVQALDAGANDYVTKPFGIQEFLARVRALLRQASGSDKPESALEFGPLTVDLAYRRVLLDGLEVALTRKEY
AVLAQLARHPGRVITQQQLLKDIWGPTHTEDSHYLRIVVGHLRQKLADDPTAPRFILTEPGIGYRLLADH
>Mature_229_residues
SQATTILVIDDEPQIRKFLRISLASQGYKVLEAATGAEGLTQAALNKPDLLVLDLGLPDMDGQQVLSEFREWSAVPVLVL
SVRASEAQKVQALDAGANDYVTKPFGIQEFLARVRALLRQASGSDKPESALEFGPLTVDLAYRRVLLDGLEVALTRKEYA
VLAQLARHPGRVITQQQLLKDIWGPTHTEDSHYLRIVVGHLRQKLADDPTAPRFILTEPGIGYRLLADH

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=52.0179372197309, Blast_Score=236, Evalue=8e-64,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=36.4864864864865, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=34.9775784753363, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=33.0316742081448, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1789809, Length=238, Percent_Identity=30.2521008403361, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=33.9285714285714, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=36.036036036036, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=32.7510917030568, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=28.6324786324786, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=34.9137931034483, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=30.2631578947368, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=30.3030303030303, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=29.1304347826087, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=28.8702928870293, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=35.7142857142857, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1790299, Length=137, Percent_Identity=31.3868613138686, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788905, Length=100, Percent_Identity=37, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788713, Length=107, Percent_Identity=31.7757009345794, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25369; Mature: 25238

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQATTILVIDDEPQIRKFLRISLASQGYKVLEAATGAEGLTQAALNKPDLLVLDLGLPD
CCCCEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCC
MDGQQVLSEFREWSAVPVLVLSVRASEAQKVQALDAGANDYVTKPFGIQEFLARVRALLR
CCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
QASGSDKPESALEFGPLTVDLAYRRVLLDGLEVALTRKEYAVLAQLARHPGRVITQQQLL
HHCCCCCCCHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KDIWGPTHTEDSHYLRIVVGHLRQKLADDPTAPRFILTEPGIGYRLLADH
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCC
>Mature Secondary Structure 
SQATTILVIDDEPQIRKFLRISLASQGYKVLEAATGAEGLTQAALNKPDLLVLDLGLPD
CCCEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCC
MDGQQVLSEFREWSAVPVLVLSVRASEAQKVQALDAGANDYVTKPFGIQEFLARVRALLR
CCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
QASGSDKPESALEFGPLTVDLAYRRVLLDGLEVALTRKEYAVLAQLARHPGRVITQQQLL
HHCCCCCCCHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KDIWGPTHTEDSHYLRIVVGHLRQKLADDPTAPRFILTEPGIGYRLLADH
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]