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The map label for this gene is mcpB [H]

Identifier: 66044551

GI number: 66044551

Start: 1478451

End: 1480073

Strand: Direct

Name: mcpB [H]

Synonym: Psyr_1303

Alternate gene names: 66044551

Gene position: 1478451-1480073 (Clockwise)

Preceding gene: 66044549

Following gene: 66044552

Centisome position: 24.26

GC content: 61.31

Gene sequence:

>1623_bases
GTGAAGAACTGGACCTTGCGCCAACGGATTCTGGCGAGTTTCGCCGTCATCATCGCAATCATGTTACTGATGGTCGTTGT
ATCTTATTCACGGTTGTTGTCCATCGAGTCCAGCGAGGAAGATGTGCGGCTTGATGCGTTGCCCGGCGTCTACTACAGCA
CCCTGGTGCGCAGTGCCTGGGGCGAGAGTTACATCCGCACGCTGGAGCTGATTGCCGAAGGGCAGGGGCGGCCGCTGACC
AAGCAGGAACGAGACCAGTTTCAGGGCTTTGACGAAAACCTGCAGGCACAGATGGACGGCTACAAGAAGTCCATCTTCGA
TGATACGGACAGAGACAGCTTCGCGCTTTTCGAAAAGCGCCGCGAGGCCTATTCGCGCATGCTCGCCGATGTTCACGCCA
AGTACGATCGCGGCGACTACGCAGGCGCGCGCGCCGAGTTCTATGGCGAAGTCAACCCGGTCTGGCTCGCGGGCCGCAAG
CAGCTCAATGATCTTATCGTGGCCAACAAACAGCTGGCGGATCAGGCCACCACCAATATCGTCAATGCCGTGCTGGCTGC
CAAGATCAGCATGGTGCTCTCTCTGCTGATCGCGGTCATGGCCGCAGCGGCCTGCGGGCTGTTGTTGATGCGTTCGATCA
TGGCACCGATGCAACTGATCGTGCGGATCCTGGACGTCATGCGTACCGGCGACCTGAGCACCCGCTTGAGCCTGTCCCGC
AAGGACGAGTTCAATGCCGTCGAGACCGGCTTCAACGACATGGTCACCGAGCTCACCGCGCTGGTTGCGCAGGCGCAGCG
CTCTTCGGTACAGGTCACCACATCGGTGACGGAAATCGCTGCAACGTCCCGCCAGCAGCAGGCTACCGCCACCGAGACCG
CTGCAACCACCACCGAGATCGGCGCCACATCGCGGGAAATTGCCGCCACCTCGCGGGATCTGGTGCGGACCATGACCGAA
GTCACCTCGGCGGCAGACCAGGCGTCGGTGCTCGCCGGCTCCGGCCAGCAGGGCCTGGCACGCATGGAAGACACCATGCA
TCAGGTGATGGGCGCTGCCAATCTGGTCAACGCCAAGCTGGCGATCCTCAACGAGAAGGCCGGCAACATCAATCAGGTCG
TCGTCACTATCGTCAAGGTCGCCGACCAGACCAACCTGCTGTCGCTCAATGCCGCCATCGAGGCCGAGAAGGCCGGTGAG
TACGGTCGCGGGTTTGCAGTGGTTGCCACCGAGGTCCGTCGCCTCGCCGACCAGACGGCTGTCGCCACTTATGACATCGA
GCAAATGGTGCGTGAAATCCAGTCGGCGGTGTCTGCTGGGGTGATGGGCATGGACAAGTTTTCCGAAGAGGTGCGCCGCG
GCATGTTCGAGGTCACGCAGGTCGGCGAGCAATTGTCGCAGATCATCCATCAGGTTCAGGCGTTGGCACCCCGTGTGCTG
ATGGTCAACGAAGGCATGCAGGCCCAGGCCACCGGCGCCGAACAGATCAACCAGGCGCTGGTGCAACTGGCGGATGCCAG
CAGCCAGACCGTCGAATCACTGCGTCAAGCCAGTTTCGCCATCGACGAATTGAGTCAGGTCGCGGTCGGGCTGCGCAGTG
GCGTTTCGCGTTTCAAGGTCTGA

Upstream 100 bases:

>100_bases
AACGTTTGACGGCTGGGCTATACTCACGCCGTTTGGACCGTTCGTCGGTCCGCTTCTTGAACACGGCCCGACGCCGTCGT
TGAACTCTTGAGGGCTGACT

Downstream 100 bases:

>100_bases
AGGATCAATGAGTGATCAATCGCCGAGGCGCAATGGCCCGCCACTGACCGCCAGCAAGCTCTTTCTGCTGTTTTGCATAG
GCGAAGACCGCTATGCACTG

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MKNWTLRQRILASFAVIIAIMLLMVVVSYSRLLSIESSEEDVRLDALPGVYYSTLVRSAWGESYIRTLELIAEGQGRPLT
KQERDQFQGFDENLQAQMDGYKKSIFDDTDRDSFALFEKRREAYSRMLADVHAKYDRGDYAGARAEFYGEVNPVWLAGRK
QLNDLIVANKQLADQATTNIVNAVLAAKISMVLSLLIAVMAAAACGLLLMRSIMAPMQLIVRILDVMRTGDLSTRLSLSR
KDEFNAVETGFNDMVTELTALVAQAQRSSVQVTTSVTEIAATSRQQQATATETAATTTEIGATSREIAATSRDLVRTMTE
VTSAADQASVLAGSGQQGLARMEDTMHQVMGAANLVNAKLAILNEKAGNINQVVVTIVKVADQTNLLSLNAAIEAEKAGE
YGRGFAVVATEVRRLADQTAVATYDIEQMVREIQSAVSAGVMGMDKFSEEVRRGMFEVTQVGEQLSQIIHQVQALAPRVL
MVNEGMQAQATGAEQINQALVQLADASSQTVESLRQASFAIDELSQVAVGLRSGVSRFKV

Sequences:

>Translated_540_residues
MKNWTLRQRILASFAVIIAIMLLMVVVSYSRLLSIESSEEDVRLDALPGVYYSTLVRSAWGESYIRTLELIAEGQGRPLT
KQERDQFQGFDENLQAQMDGYKKSIFDDTDRDSFALFEKRREAYSRMLADVHAKYDRGDYAGARAEFYGEVNPVWLAGRK
QLNDLIVANKQLADQATTNIVNAVLAAKISMVLSLLIAVMAAAACGLLLMRSIMAPMQLIVRILDVMRTGDLSTRLSLSR
KDEFNAVETGFNDMVTELTALVAQAQRSSVQVTTSVTEIAATSRQQQATATETAATTTEIGATSREIAATSRDLVRTMTE
VTSAADQASVLAGSGQQGLARMEDTMHQVMGAANLVNAKLAILNEKAGNINQVVVTIVKVADQTNLLSLNAAIEAEKAGE
YGRGFAVVATEVRRLADQTAVATYDIEQMVREIQSAVSAGVMGMDKFSEEVRRGMFEVTQVGEQLSQIIHQVQALAPRVL
MVNEGMQAQATGAEQINQALVQLADASSQTVESLRQASFAIDELSQVAVGLRSGVSRFKV
>Mature_540_residues
MKNWTLRQRILASFAVIIAIMLLMVVVSYSRLLSIESSEEDVRLDALPGVYYSTLVRSAWGESYIRTLELIAEGQGRPLT
KQERDQFQGFDENLQAQMDGYKKSIFDDTDRDSFALFEKRREAYSRMLADVHAKYDRGDYAGARAEFYGEVNPVWLAGRK
QLNDLIVANKQLADQATTNIVNAVLAAKISMVLSLLIAVMAAAACGLLLMRSIMAPMQLIVRILDVMRTGDLSTRLSLSR
KDEFNAVETGFNDMVTELTALVAQAQRSSVQVTTSVTEIAATSRQQQATATETAATTTEIGATSREIAATSRDLVRTMTE
VTSAADQASVLAGSGQQGLARMEDTMHQVMGAANLVNAKLAILNEKAGNINQVVVTIVKVADQTNLLSLNAAIEAEKAGE
YGRGFAVVATEVRRLADQTAVATYDIEQMVREIQSAVSAGVMGMDKFSEEVRRGMFEVTQVGEQLSQIIHQVQALAPRVL
MVNEGMQAQATGAEQINQALVQLADASSQTVESLRQASFAIDELSQVAVGLRSGVSRFKV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=353, Percent_Identity=25.7790368271955, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788194, Length=356, Percent_Identity=26.9662921348315, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788195, Length=267, Percent_Identity=29.2134831460674, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI2367378, Length=379, Percent_Identity=27.7044854881267, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789453, Length=367, Percent_Identity=23.1607629427793, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 58830; Mature: 58830

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNWTLRQRILASFAVIIAIMLLMVVVSYSRLLSIESSEEDVRLDALPGVYYSTLVRSAW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHH
GESYIRTLELIAEGQGRPLTKQERDQFQGFDENLQAQMDGYKKSIFDDTDRDSFALFEKR
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
REAYSRMLADVHAKYDRGDYAGARAEFYGEVNPVWLAGRKQLNDLIVANKQLADQATTNI
HHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
VNAVLAAKISMVLSLLIAVMAAAACGLLLMRSIMAPMQLIVRILDVMRTGDLSTRLSLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
KDEFNAVETGFNDMVTELTALVAQAQRSSVQVTTSVTEIAATSRQQQATATETAATTTEI
CCCCHHHHCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GATSREIAATSRDLVRTMTEVTSAADQASVLAGSGQQGLARMEDTMHQVMGAANLVNAKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AILNEKAGNINQVVVTIVKVADQTNLLSLNAAIEAEKAGEYGRGFAVVATEVRRLADQTA
HEEECCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VATYDIEQMVREIQSAVSAGVMGMDKFSEEVRRGMFEVTQVGEQLSQIIHQVQALAPRVL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
MVNEGMQAQATGAEQINQALVQLADASSQTVESLRQASFAIDELSQVAVGLRSGVSRFKV
EECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNWTLRQRILASFAVIIAIMLLMVVVSYSRLLSIESSEEDVRLDALPGVYYSTLVRSAW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHH
GESYIRTLELIAEGQGRPLTKQERDQFQGFDENLQAQMDGYKKSIFDDTDRDSFALFEKR
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
REAYSRMLADVHAKYDRGDYAGARAEFYGEVNPVWLAGRKQLNDLIVANKQLADQATTNI
HHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
VNAVLAAKISMVLSLLIAVMAAAACGLLLMRSIMAPMQLIVRILDVMRTGDLSTRLSLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
KDEFNAVETGFNDMVTELTALVAQAQRSSVQVTTSVTEIAATSRQQQATATETAATTTEI
CCCCHHHHCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GATSREIAATSRDLVRTMTEVTSAADQASVLAGSGQQGLARMEDTMHQVMGAANLVNAKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AILNEKAGNINQVVVTIVKVADQTNLLSLNAAIEAEKAGEYGRGFAVVATEVRRLADQTA
HEEECCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VATYDIEQMVREIQSAVSAGVMGMDKFSEEVRRGMFEVTQVGEQLSQIIHQVQALAPRVL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
MVNEGMQAQATGAEQINQALVQLADASSQTVESLRQASFAIDELSQVAVGLRSGVSRFKV
EECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]