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The map label for this gene is lspA [H]

Identifier: 66043976

GI number: 66043976

Start: 816344

End: 816850

Strand: Direct

Name: lspA [H]

Synonym: Psyr_0711

Alternate gene names: 66043976

Gene position: 816344-816850 (Clockwise)

Preceding gene: 66043975

Following gene: 66043977

Centisome position: 13.4

GC content: 60.95

Gene sequence:

>507_bases
ATGCCTAACGCCTCGTTTGGCCGTCTGGCCTGGCTGTGGTTGAGCGTGCTGGTTCTGGTCATTGACCAGGCCAGCAAGTA
TTACTTCGAGAACGCGTTGAGCCTGTATCAGCAGATCATCGTGATTCCCGACCTGTTCAGCTGGACCCTGGCCTACAACA
CCGGTGCCGCCTTCAGTTTTCTGGCCGACGGTGCCGGCTGGCAGCGCTGGCTGTTCGCCCTGATCGCGGTGGTGGTCAGC
GCCGTGCTGGTCGTCTGGCTCAAACGCCTGGGTCGTGACGACACGTGGCTGGCCGTTGCACTGGCGCTGGTGCTGGGCGG
CGCACTGGGCAACCTCTACGACCGTATCGTGCTGGGCCACGTGATCGACTTCATCCTGGTTCACTGGCAGAACCGCTGGT
ACTTCCCTGCATTCAACGTCGCGGACAGTGCGATCAGCGTCGGCGCAGTCATGCTGGCGCTGGACATGTTCAAGAGCAAG
AAAACCGGAGAGACCGTCAATGACTGA

Upstream 100 bases:

>100_bases
TGCTGGCATCACCGCGAGGATGTAGGGGTCAACCCCGAGCATCCGGAAATCTGCGGTCGTTGCGTAGACAACATCAGCGG
TGCAGGCGAGGTCCGTCACT

Downstream 100 bases:

>100_bases
GCAATCTTCGACTCAAGGCTCGTCTGACGAGCTGCGCATCGGTCAGAACACGCAGGTCACTCTGCACTTCGCCCTGCGTC
TGGAAAACGGCGATACCGTC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MPNASFGRLAWLWLSVLVLVIDQASKYYFENALSLYQQIIVIPDLFSWTLAYNTGAAFSFLADGAGWQRWLFALIAVVVS
AVLVVWLKRLGRDDTWLAVALALVLGGALGNLYDRIVLGHVIDFILVHWQNRWYFPAFNVADSAISVGAVMLALDMFKSK
KTGETVND

Sequences:

>Translated_168_residues
MPNASFGRLAWLWLSVLVLVIDQASKYYFENALSLYQQIIVIPDLFSWTLAYNTGAAFSFLADGAGWQRWLFALIAVVVS
AVLVVWLKRLGRDDTWLAVALALVLGGALGNLYDRIVLGHVIDFILVHWQNRWYFPAFNVADSAISVGAVMLALDMFKSK
KTGETVND
>Mature_167_residues
PNASFGRLAWLWLSVLVLVIDQASKYYFENALSLYQQIIVIPDLFSWTLAYNTGAAFSFLADGAGWQRWLFALIAVVVSA
VLVVWLKRLGRDDTWLAVALALVLGGALGNLYDRIVLGHVIDFILVHWQNRWYFPAFNVADSAISVGAVMLALDMFKSKK
TGETVND

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=156, Percent_Identity=44.2307692307692, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18758; Mature: 18627

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNASFGRLAWLWLSVLVLVIDQASKYYFENALSLYQQIIVIPDLFSWTLAYNTGAAFSF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LADGAGWQRWLFALIAVVVSAVLVVWLKRLGRDDTWLAVALALVLGGALGNLYDRIVLGH
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VIDFILVHWQNRWYFPAFNVADSAISVGAVMLALDMFKSKKTGETVND
HHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PNASFGRLAWLWLSVLVLVIDQASKYYFENALSLYQQIIVIPDLFSWTLAYNTGAAFSF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LADGAGWQRWLFALIAVVVSAVLVVWLKRLGRDDTWLAVALALVLGGALGNLYDRIVLGH
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VIDFILVHWQNRWYFPAFNVADSAISVGAVMLALDMFKSKKTGETVND
HHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA