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The map label for this gene is insO2 [H]

Identifier: 66043919

GI number: 66043919

Start: 740007

End: 740789

Strand: Direct

Name: insO2 [H]

Synonym: Psyr_0652

Alternate gene names: 66043919

Gene position: 740007-740789 (Clockwise)

Preceding gene: 66043918

Following gene: 66043923

Centisome position: 12.14

GC content: 55.17

Gene sequence:

>783_bases
ATGAACCGCAGCCGGTATTACGACTATCTGAAGCAGCGGGATCGAGTTGATCCCGACAGAGAACGGCTCAAGGTCGAGGC
GATTCAATTGCACACTCAAAGTCGCCGATCAATGGGAGCTCGCAGTTTGTCAGCGGCCTTGAAAGCCCGGGGTGAGCAGG
TTGGCAGGTTTTTGGCTGGTCGTCTGATGGCCGAGGCGGGTTTGCAAAGCTGTCAGCGTCGACCGAGGCCTTATCGGCAT
AGCGTCGTGCAATCCCGATTCGCCGAGAATTTGCTGGAACGCCAATTTGAAGTATCAGCCCCCAATCAGGTCTGGTGCGG
AGATATAACGTATATCTGGGCTGGTACGCGCTGGGTATATCTGGCGGCTGTGCTTGACCTGTACGCCAGGCGGATAGTGG
GTTGGGCGATTTCCAGCACACCAGACTCAACGTTGACTTGCAAGGCGCTGGCATTGGCTCATGAAGCTCGAGGAAAGCCA
CACAAGGTCATGTTTCACTCCGACCAAGGCTGCCAGTACAGTAGCGAGATGTTCCGCACTAAACTTGAGTCGCTCGGTAT
GCAGCAGAGCATGAGCCGTCGCGGAAACTGCTGGGACAATGCCCCGATGGAACGCTTTTTCGGCAGCCTGAAGTCCGAAT
GGATACCGAAAAAGGGCTATCGGAACGAGGAGGAAGCACGCCCTGATGTGCTTCGTTACGTAATCCATCACTACAATCAG
GTCAGGCTGCACAGCTACAACGAATACCGCACGCCAGTGGATCAGGAAAAAATGGCGGCGTAG

Upstream 100 bases:

>100_bases
AGGCTACCGCTCTCTTGATGTCCGATTCCCTCGATCGGTGATTCTGATCGAGAAGTTGAGTGAGCGTTTTACTGTGACTG
ACTTGTGCCGTGTGTTTGGA

Downstream 100 bases:

>100_bases
CTTCTATAACTGTGTCCGGAATCAGTTGACCAGATCACAGGCGCGCTGTTTTCGGAGCCTGTACGGGCCCTTTCGCGAGC
AAGCTCGCTCCCACAGGGAG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MNRSRYYDYLKQRDRVDPDRERLKVEAIQLHTQSRRSMGARSLSAALKARGEQVGRFLAGRLMAEAGLQSCQRRPRPYRH
SVVQSRFAENLLERQFEVSAPNQVWCGDITYIWAGTRWVYLAAVLDLYARRIVGWAISSTPDSTLTCKALALAHEARGKP
HKVMFHSDQGCQYSSEMFRTKLESLGMQQSMSRRGNCWDNAPMERFFGSLKSEWIPKKGYRNEEEARPDVLRYVIHHYNQ
VRLHSYNEYRTPVDQEKMAA

Sequences:

>Translated_260_residues
MNRSRYYDYLKQRDRVDPDRERLKVEAIQLHTQSRRSMGARSLSAALKARGEQVGRFLAGRLMAEAGLQSCQRRPRPYRH
SVVQSRFAENLLERQFEVSAPNQVWCGDITYIWAGTRWVYLAAVLDLYARRIVGWAISSTPDSTLTCKALALAHEARGKP
HKVMFHSDQGCQYSSEMFRTKLESLGMQQSMSRRGNCWDNAPMERFFGSLKSEWIPKKGYRNEEEARPDVLRYVIHHYNQ
VRLHSYNEYRTPVDQEKMAA
>Mature_260_residues
MNRSRYYDYLKQRDRVDPDRERLKVEAIQLHTQSRRSMGARSLSAALKARGEQVGRFLAGRLMAEAGLQSCQRRPRPYRH
SVVQSRFAENLLERQFEVSAPNQVWCGDITYIWAGTRWVYLAAVLDLYARRIVGWAISSTPDSTLTCKALALAHEARGKP
HKVMFHSDQGCQYSSEMFRTKLESLGMQQSMSRRGNCWDNAPMERFFGSLKSEWIPKKGYRNEEEARPDVLRYVIHHYNQ
VRLHSYNEYRTPVDQEKMAA

Specific function: Involved in the transposition of the insertion sequence IS911B [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=179, Percent_Identity=36.8715083798883, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI1788405, Length=254, Percent_Identity=34.251968503937, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1787263, Length=254, Percent_Identity=34.251968503937, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1786753, Length=254, Percent_Identity=34.251968503937, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1786570, Length=254, Percent_Identity=34.251968503937, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1786490, Length=254, Percent_Identity=34.251968503937, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1789981, Length=255, Percent_Identity=32.156862745098, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 30326; Mature: 30326

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSRYYDYLKQRDRVDPDRERLKVEAIQLHTQSRRSMGARSLSAALKARGEQVGRFLAG
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLMAEAGLQSCQRRPRPYRHSVVQSRFAENLLERQFEVSAPNQVWCGDITYIWAGTRWVY
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEEEEECCHHHHH
LAAVLDLYARRIVGWAISSTPDSTLTCKALALAHEARGKPHKVMFHSDQGCQYSSEMFRT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
KLESLGMQQSMSRRGNCWDNAPMERFFGSLKSEWIPKKGYRNEEEARPDVLRYVIHHYNQ
HHHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHCCH
VRLHSYNEYRTPVDQEKMAA
HEECCCHHHCCCCCHHHCCC
>Mature Secondary Structure
MNRSRYYDYLKQRDRVDPDRERLKVEAIQLHTQSRRSMGARSLSAALKARGEQVGRFLAG
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLMAEAGLQSCQRRPRPYRHSVVQSRFAENLLERQFEVSAPNQVWCGDITYIWAGTRWVY
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEEEEECCHHHHH
LAAVLDLYARRIVGWAISSTPDSTLTCKALALAHEARGKPHKVMFHSDQGCQYSSEMFRT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
KLESLGMQQSMSRRGNCWDNAPMERFFGSLKSEWIPKKGYRNEEEARPDVLRYVIHHYNQ
HHHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHCCH
VRLHSYNEYRTPVDQEKMAA
HEECCCHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]