The gene/protein map for NC_007005 is currently unavailable.
Definition Pseudomonas syringae pv. syringae B728a, complete genome.
Accession NC_007005
Length 6,093,698

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The map label for this gene is sdh [H]

Identifier: 66043869

GI number: 66043869

Start: 691538

End: 692302

Strand: Direct

Name: sdh [H]

Synonym: Psyr_0602

Alternate gene names: 66043869

Gene position: 691538-692302 (Clockwise)

Preceding gene: 66043868

Following gene: 66043877

Centisome position: 11.35

GC content: 61.96

Gene sequence:

>765_bases
ATGACTTCCACTGTATTCATCACGGGCGCCACTTCCGGTTTTGGCGAGGCGTGTGCCCGTCGTTTCGCCGAGGCGGGCTG
GTCGCTGGTGCTGACCGGTCGACGCAAGGACCGCCTGGATACCTTGAGCGCCGAGCTGTCGAAGCAGACCAAGGTGCATA
CGCTGGTGCTGGATGTACGTGACCGCAAGGCGATGGAGAGCGCCATCGCAGGTTTGCCTGAAGAGTTCGGCAGCATTCGC
GGGCTGATCAACAATGCCGGTCTGGCGCTGGGAATCGATCCTGCGCCCAAGTGCGATCTGGATGACTGGGACACCATGAT
CGACACCAACGTCAAAGGTCTGGTGTACACCACGCGTCTGCTGCTGCCGCGTCTGATCGCGCACGGTCGCGGCGCGAGCA
TCGTCAACCTGGGTTCGGTCGCCGGTAACTACCCGTATCTGGGCGGCAACGTCTACGGTGGCACCAAGGCCTTTGTCGGG
CAGTTCTCGCTGAACCTGCGCAACGACCTGATCGGCACCGGCGTGCGCGTCACCAACCTTGAGCCGGGGCTGTGCGAGAG
CGAGTTTTCGCTGGTGCGTTTCGGCGGTGATCAGGCCAAGTACGACGCCACCTACGCAGGTGCCGAGCCGATTCAGCCTC
AGGACATCGCCGACACCATCTTCTGGATCATGAACACACCCGCGCACGTCAACATCAACAGCCTGGAACTGATGCCTGTC
AGCCAGACCTGGGCCGGCTTTGCGATTGATCGCAACCGCGGTTGA

Upstream 100 bases:

>100_bases
TCGGTTGTTGCATCGATGTCCCGCTGACGGGCATTCTGCTGCCCTTGCCAGAAACTTATTAACAGGCAGCGCTGTTTTTG
CGCCATGTCAGGAGAATGAA

Downstream 100 bases:

>100_bases
TTGATTGCTGATCGGGCCGCGCAGCTGCGGCCCGATCAGCTGTCTGCGGGTGTTGGCGGCGGGAATGCACTGACGAAGCG
ATTTTCGACGAAATCTGCCA

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTSTVFITGATSGFGEACARRFAEAGWSLVLTGRRKDRLDTLSAELSKQTKVHTLVLDVRDRKAMESAIAGLPEEFGSIR
GLINNAGLALGIDPAPKCDLDDWDTMIDTNVKGLVYTTRLLLPRLIAHGRGASIVNLGSVAGNYPYLGGNVYGGTKAFVG
QFSLNLRNDLIGTGVRVTNLEPGLCESEFSLVRFGGDQAKYDATYAGAEPIQPQDIADTIFWIMNTPAHVNINSLELMPV
SQTWAGFAIDRNRG

Sequences:

>Translated_254_residues
MTSTVFITGATSGFGEACARRFAEAGWSLVLTGRRKDRLDTLSAELSKQTKVHTLVLDVRDRKAMESAIAGLPEEFGSIR
GLINNAGLALGIDPAPKCDLDDWDTMIDTNVKGLVYTTRLLLPRLIAHGRGASIVNLGSVAGNYPYLGGNVYGGTKAFVG
QFSLNLRNDLIGTGVRVTNLEPGLCESEFSLVRFGGDQAKYDATYAGAEPIQPQDIADTIFWIMNTPAHVNINSLELMPV
SQTWAGFAIDRNRG
>Mature_253_residues
TSTVFITGATSGFGEACARRFAEAGWSLVLTGRRKDRLDTLSAELSKQTKVHTLVLDVRDRKAMESAIAGLPEEFGSIRG
LINNAGLALGIDPAPKCDLDDWDTMIDTNVKGLVYTTRLLLPRLIAHGRGASIVNLGSVAGNYPYLGGNVYGGTKAFVGQ
FSLNLRNDLIGTGVRVTNLEPGLCESEFSLVRFGGDQAKYDATYAGAEPIQPQDIADTIFWIMNTPAHVNINSLELMPVS
QTWAGFAIDRNRG

Specific function: Catalyzes the oxidation of the hydroxyl group of serine to form 2-aminomalonate semialdehyde which is spontaneously converted into 2-aminoacetaldehyde and CO(2). Also acts on D- serine, L-glycerate, D-glycerate and 2-methyl-DL-serine. Does not act on O-me

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=27.8225806451613, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI20149619, Length=227, Percent_Identity=33.4801762114537, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI7705855, Length=198, Percent_Identity=31.3131313131313, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI40548397, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI214010158, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI214010156, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI22758144, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI150247226, Length=181, Percent_Identity=33.7016574585635, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI7706318, Length=207, Percent_Identity=31.4009661835749, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI22507405, Length=181, Percent_Identity=30.939226519337, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI19743808, Length=181, Percent_Identity=30.939226519337, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI19923817, Length=234, Percent_Identity=21.3675213675214, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI5031737, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI32483357, Length=186, Percent_Identity=28.494623655914, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI10190704, Length=224, Percent_Identity=29.0178571428571, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=27.6041666666667, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI50726952, Length=183, Percent_Identity=31.6939890710383, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787820, Length=248, Percent_Identity=53.2258064516129, Blast_Score=271, Evalue=4e-74,
Organism=Escherichia coli, GI87082100, Length=190, Percent_Identity=34.2105263157895, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=26.4462809917355, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI87082160, Length=195, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788459, Length=187, Percent_Identity=24.5989304812834, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=230, Percent_Identity=28.695652173913, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=229, Percent_Identity=27.9475982532751, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=244, Percent_Identity=29.0983606557377, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=241, Percent_Identity=28.6307053941909, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=245, Percent_Identity=29.3877551020408, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=242, Percent_Identity=29.7520661157025, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=193, Percent_Identity=31.0880829015544, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=226, Percent_Identity=26.5486725663717, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=241, Percent_Identity=29.045643153527, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=238, Percent_Identity=27.3109243697479, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=240, Percent_Identity=28.75, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=205, Percent_Identity=31.7073170731707, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=237, Percent_Identity=28.6919831223629, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=239, Percent_Identity=29.2887029288703, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=188, Percent_Identity=29.2553191489362, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=192, Percent_Identity=28.125, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=239, Percent_Identity=27.1966527196653, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=243, Percent_Identity=27.1604938271605, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115534660, Length=182, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=201, Percent_Identity=27.8606965174129, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=202, Percent_Identity=27.7227722772277, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=240, Percent_Identity=27.5, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=36.9918699186992, Blast_Score=159, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=26.0204081632653, Blast_Score=75, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6319635, Length=204, Percent_Identity=27.4509803921569, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007236, Length=249, Percent_Identity=28.1124497991968, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI23397609, Length=182, Percent_Identity=34.6153846153846, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24643142, Length=194, Percent_Identity=31.4432989690722, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28571387, Length=250, Percent_Identity=28.4, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24644339, Length=233, Percent_Identity=29.1845493562232, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640442, Length=216, Percent_Identity=29.1666666666667, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24663911, Length=248, Percent_Identity=25.8064516129032, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641388, Length=257, Percent_Identity=27.6264591439689, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21357041, Length=235, Percent_Identity=28.936170212766, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI116007234, Length=250, Percent_Identity=27.6, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641232, Length=251, Percent_Identity=26.2948207171315, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355319, Length=198, Percent_Identity=30.8080808080808, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281364494, Length=250, Percent_Identity=24.8, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24648693, Length=248, Percent_Identity=26.6129032258064, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355889, Length=248, Percent_Identity=26.6129032258064, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=233, Percent_Identity=27.8969957081545, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21358495, Length=224, Percent_Identity=26.7857142857143, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24648944, Length=239, Percent_Identity=25.9414225941423, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584748, Length=182, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161076933, Length=182, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007238, Length=183, Percent_Identity=29.5081967213115, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574402, Length=195, Percent_Identity=29.7435897435897, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584744, Length=195, Percent_Identity=29.7435897435897, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17737361, Length=189, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.276 [H]

Molecular weight: Translated: 27382; Mature: 27251

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTSTVFITGATSGFGEACARRFAEAGWSLVLTGRRKDRLDTLSAELSKQTKVHTLVLDVR
CCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECH
DRKAMESAIAGLPEEFGSIRGLINNAGLALGIDPAPKCDLDDWDTMIDTNVKGLVYTTRL
HHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHCCCCCHHHHHHHH
LLPRLIAHGRGASIVNLGSVAGNYPYLGGNVYGGTKAFVGQFSLNLRNDLIGTGVRVTNL
HHHHHHHCCCCCCEEEECCCCCCCCCCCCEECCCHHHEEEEEEECCCCCCCCCCEEEECC
EPGLCESEFSLVRFGGDQAKYDATYAGAEPIQPQDIADTIFWIMNTPAHVNINSLELMPV
CCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHEECCCCEEEECCEEEEEC
SQTWAGFAIDRNRG
CCCCCCEEEECCCC
>Mature Secondary Structure 
TSTVFITGATSGFGEACARRFAEAGWSLVLTGRRKDRLDTLSAELSKQTKVHTLVLDVR
CCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECH
DRKAMESAIAGLPEEFGSIRGLINNAGLALGIDPAPKCDLDDWDTMIDTNVKGLVYTTRL
HHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHCCCCCHHHHHHHH
LLPRLIAHGRGASIVNLGSVAGNYPYLGGNVYGGTKAFVGQFSLNLRNDLIGTGVRVTNL
HHHHHHHCCCCCCEEEECCCCCCCCCCCCEECCCHHHEEEEEEECCCCCCCCCCEEEECC
EPGLCESEFSLVRFGGDQAKYDATYAGAEPIQPQDIADTIFWIMNTPAHVNINSLELMPV
CCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHEECCCCEEEECCEEEEEC
SQTWAGFAIDRNRG
CCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]