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The map label for this gene is motA [H]

Identifier: 66043828

GI number: 66043828

Start: 637990

End: 638841

Strand: Direct

Name: motA [H]

Synonym: Psyr_0561

Alternate gene names: 66043828

Gene position: 637990-638841 (Clockwise)

Preceding gene: 66043824

Following gene: 66043829

Centisome position: 10.47

GC content: 58.1

Gene sequence:

>852_bases
ATGGCTAAAATCATCGGCATCATTGTCGTTCTCGCAAGTGTCATCGGCGGATATGTGCTGTCCCATGGCAAGGTCATGGC
GCTGTTCCAACCGTACGAGGTCTTGATTATCGGCGGTGCTGCACTGGGCGCGTTCCTCCAGGCCAACCCAGGCTACATGT
TCATGCACGTGTTCAAGAAGTCGCTGAAGATGTTCGGTACGCGCTTCACACATGCCTATTACCTTGAAGTGCTGGGGCTG
GTCTACGAAATCCTCAACAAGAGCCGCCGTGAAGGCATGATGGCGATCGAAGGGGATATCGAAGACGCTGCCTCCAGCCC
GATCTTCGCCAAATACCCGGGTGTCCTCAAGGATGAGCGCATGACTGCGTACATCTGCGATTACCTGCGCATCATGTCGT
CCGGCAACATGGCTCCTCACGAGCTGGAAGGTCTGTTCGACATGGAGCTGCTGAGCATGAAAGAAGACCTCGAGCATCCA
TCCCACGCCATTACCGGTATCGCCGACGGTATGCCCGGCTTCGGTATCGTGGCTGCGGTACTGGGTATCGTGGTGACCAT
GGCGTCGCTGGGTTCGGGCGACAAGGCAGCGATCGGCATGCACGTAGGTGCGGCGCTGGTCGGTACGTTCTTCGGTATTC
TCGCGGCTTACGGTTTCTTCGGTCCTCTGGCCACCAGCCTTGCGCATGATGCCAAGGAAGAAATGAACGTCTACGAGAGC
ATCAAGGCGTCGCTGGTGGCCTCGGCCTCCGGCATGCCGCCTTCGCTGGCTGTCGAATTCGGCCGCAAGGTTCTCTATCC
GCTGCATCGCCCCAGCTTCAGCGAGCTGGAACAAGCGGTTCGCGGTCGCTAA

Upstream 100 bases:

>100_bases
AACTGGCTATAGTCTGGCCCAGTTAGGCCGATAAGGAGAAGAAGAGATTCAACAACTTCCGGACTGTCCCTGAACCCGAC
TCAGTAAAGTATTTTTTCCT

Downstream 100 bases:

>100_bases
GTCATGGAAAATAATCAGCCGATTATCATCAAGCGCGTAAAGCGCTTTGGTGGCGGACATCACGGCGGTGCCTGGAAGAT
CGCATTTGCCGACTTCGCGA

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MAKIIGIIVVLASVIGGYVLSHGKVMALFQPYEVLIIGGAALGAFLQANPGYMFMHVFKKSLKMFGTRFTHAYYLEVLGL
VYEILNKSRREGMMAIEGDIEDAASSPIFAKYPGVLKDERMTAYICDYLRIMSSGNMAPHELEGLFDMELLSMKEDLEHP
SHAITGIADGMPGFGIVAAVLGIVVTMASLGSGDKAAIGMHVGAALVGTFFGILAAYGFFGPLATSLAHDAKEEMNVYES
IKASLVASASGMPPSLAVEFGRKVLYPLHRPSFSELEQAVRGR

Sequences:

>Translated_283_residues
MAKIIGIIVVLASVIGGYVLSHGKVMALFQPYEVLIIGGAALGAFLQANPGYMFMHVFKKSLKMFGTRFTHAYYLEVLGL
VYEILNKSRREGMMAIEGDIEDAASSPIFAKYPGVLKDERMTAYICDYLRIMSSGNMAPHELEGLFDMELLSMKEDLEHP
SHAITGIADGMPGFGIVAAVLGIVVTMASLGSGDKAAIGMHVGAALVGTFFGILAAYGFFGPLATSLAHDAKEEMNVYES
IKASLVASASGMPPSLAVEFGRKVLYPLHRPSFSELEQAVRGR
>Mature_282_residues
AKIIGIIVVLASVIGGYVLSHGKVMALFQPYEVLIIGGAALGAFLQANPGYMFMHVFKKSLKMFGTRFTHAYYLEVLGLV
YEILNKSRREGMMAIEGDIEDAASSPIFAKYPGVLKDERMTAYICDYLRIMSSGNMAPHELEGLFDMELLSMKEDLEHPS
HAITGIADGMPGFGIVAAVLGIVVTMASLGSGDKAAIGMHVGAALVGTFFGILAAYGFFGPLATSLAHDAKEEMNVYESI
KASLVASASGMPPSLAVEFGRKVLYPLHRPSFSELEQAVRGR

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=284, Percent_Identity=42.6056338028169, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30380; Mature: 30249

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIIGIIVVLASVIGGYVLSHGKVMALFQPYEVLIIGGAALGAFLQANPGYMFMHVFKK
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECHHHHHHHHHCCCCHHHHHHHHH
SLKMFGTRFTHAYYLEVLGLVYEILNKSRREGMMAIEGDIEDAASSPIFAKYPGVLKDER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHCCCCEECCCCCCCCCH
MTAYICDYLRIMSSGNMAPHELEGLFDMELLSMKEDLEHPSHAITGIADGMPGFGIVAAV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHH
LGIVVTMASLGSGDKAAIGMHVGAALVGTFFGILAAYGFFGPLATSLAHDAKEEMNVYES
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKASLVASASGMPPSLAVEFGRKVLYPLHRPSFSELEQAVRGR
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
AKIIGIIVVLASVIGGYVLSHGKVMALFQPYEVLIIGGAALGAFLQANPGYMFMHVFKK
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECHHHHHHHHHCCCCHHHHHHHHH
SLKMFGTRFTHAYYLEVLGLVYEILNKSRREGMMAIEGDIEDAASSPIFAKYPGVLKDER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHCCCCEECCCCCCCCCH
MTAYICDYLRIMSSGNMAPHELEGLFDMELLSMKEDLEHPSHAITGIADGMPGFGIVAAV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHH
LGIVVTMASLGSGDKAAIGMHVGAALVGTFFGILAAYGFFGPLATSLAHDAKEEMNVYES
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKASLVASASGMPPSLAVEFGRKVLYPLHRPSFSELEQAVRGR
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]