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The map label for this gene is serB [H]

Identifier: 66043824

GI number: 66043824

Start: 631007

End: 632263

Strand: Direct

Name: serB [H]

Synonym: Psyr_0557

Alternate gene names: 66043824

Gene position: 631007-632263 (Clockwise)

Preceding gene: 66043822

Following gene: 66043828

Centisome position: 10.36

GC content: 60.14

Gene sequence:

>1257_bases
ATGTGGTTAGAATGCGTTTTTTTTCCACTGCGGGGGTGCGCCTTGCGCGAAATCGTCCTGATTAACATCACCGGTGTCGA
CCGTCCCGGTCTCACTGCAGCCATCACCGGCGTCCTCGCCCAAGGTGGCGTGAACATTCTCGATATTGGTCAGGCGGTGA
TCCATGACACCCTGTCGTTCGGCATCCTGGTTGAAATTCCGGATACTGTGCAGGGATCCTCGGTGCTCAAGGACATCCTG
TTCACCGCCTACGAACTGGATCAGCAAGTCCGTTTCACTGCGGTGTCCGAAACCGACTATCAACACTGGGTCGAAGGTCA
GGGCAAGGCGCGCCACATCGTTACGCTGCTGACCCGCAAAGTCACGGCCGAGCAATTGCAGCGCGTCAGCGCCATCACTG
CCAGGTACGGGCTGAATATCGATCAGATCGACCGGTTGTCCGGTCGCATGCCGCTCGACACCCCGGCTGACAAGGGCAAG
GGCTGCATCGAGTTCACCGTGCGCGGCGAGCCCGCCGACCCGAAAGCCATGCAGGCCGAATTTCTCGCGGTCGCCCAGGA
TCTCGACGTCGATATCGCGTTCCAGCAGGACTCGCTGTTCCGCCGCAACCGGCGCCTGGCGGTGTTCGACATGGACTCGA
CCCTCATCGAGGCCGAAGTCATCGACGAACTGGCCAAGGCCGCAGGCGTCGGCGAGCAGGTTTCCGAGATTACCGAACGT
GCCATGCGCGGCGAACTGGATTTCAGCGAAAGCTTCAAGGAACGTCTGGCTTTGCTCAAGGGCCTAGACGTGAGTGTGCT
GGATGAAATCGGCGCGTCCCTGCGTTTGACCGAAGGTGCTGAAACACTGTTCTCCGAGCTCAAGCGGCTGGGTTACAAGA
CGGCGATTCTGTCGGGAGGCTTCACCTATTTTGCCAAGCAGCTGCAAGCAAAGCTGGGCATTGATTATGTCTTCGCCAAT
GAGCTGGAAGTGGTTGACGGCAAGGTGACCGGCGTAGCGGTCGAGCCGATCGTCAATGCGCAGCGCAAGGCCGATCTGTT
GCGCGAACTGGCCCACAAGGAAGGGTTGAGCCTGGAGCAGACCATCGCGGTCGGCGACGGTGCCAATGACCTGCCGATGC
TGGCGATTGCCGGGCTGGGTGTAGCGTTTCGCGCCAAGCCATTGGTCAAGCAATCGGCCAAACAGGCCATTTCGACGCTG
GGGCTCGATGGCGTGCTGTATCTGCTGGGCTTGCGCGACCGCGAGGGAAAGCGCTGA

Upstream 100 bases:

>100_bases
GGGCCGGTTCACAGAGCACGGCTCTTTCGGTGAAGTTGTCGCGCAGTATAACGAGCGACCCAGTGGCGGCAAAGCGCTGC
CTGTGCCCGGTGGTCACTGA

Downstream 100 bases:

>100_bases
CGCTCAGGCCGTCGTGGTCTGCTCCTGATGGCGAGGGGCAATCGCGACGGCTGTCGCAATGATCGCTACAGCGTGCCCCA
CAAGGAATCGAATTCCTGAT

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MWLECVFFPLRGCALREIVLINITGVDRPGLTAAITGVLAQGGVNILDIGQAVIHDTLSFGILVEIPDTVQGSSVLKDIL
FTAYELDQQVRFTAVSETDYQHWVEGQGKARHIVTLLTRKVTAEQLQRVSAITARYGLNIDQIDRLSGRMPLDTPADKGK
GCIEFTVRGEPADPKAMQAEFLAVAQDLDVDIAFQQDSLFRRNRRLAVFDMDSTLIEAEVIDELAKAAGVGEQVSEITER
AMRGELDFSESFKERLALLKGLDVSVLDEIGASLRLTEGAETLFSELKRLGYKTAILSGGFTYFAKQLQAKLGIDYVFAN
ELEVVDGKVTGVAVEPIVNAQRKADLLRELAHKEGLSLEQTIAVGDGANDLPMLAIAGLGVAFRAKPLVKQSAKQAISTL
GLDGVLYLLGLRDREGKR

Sequences:

>Translated_418_residues
MWLECVFFPLRGCALREIVLINITGVDRPGLTAAITGVLAQGGVNILDIGQAVIHDTLSFGILVEIPDTVQGSSVLKDIL
FTAYELDQQVRFTAVSETDYQHWVEGQGKARHIVTLLTRKVTAEQLQRVSAITARYGLNIDQIDRLSGRMPLDTPADKGK
GCIEFTVRGEPADPKAMQAEFLAVAQDLDVDIAFQQDSLFRRNRRLAVFDMDSTLIEAEVIDELAKAAGVGEQVSEITER
AMRGELDFSESFKERLALLKGLDVSVLDEIGASLRLTEGAETLFSELKRLGYKTAILSGGFTYFAKQLQAKLGIDYVFAN
ELEVVDGKVTGVAVEPIVNAQRKADLLRELAHKEGLSLEQTIAVGDGANDLPMLAIAGLGVAFRAKPLVKQSAKQAISTL
GLDGVLYLLGLRDREGKR
>Mature_418_residues
MWLECVFFPLRGCALREIVLINITGVDRPGLTAAITGVLAQGGVNILDIGQAVIHDTLSFGILVEIPDTVQGSSVLKDIL
FTAYELDQQVRFTAVSETDYQHWVEGQGKARHIVTLLTRKVTAEQLQRVSAITARYGLNIDQIDRLSGRMPLDTPADKGK
GCIEFTVRGEPADPKAMQAEFLAVAQDLDVDIAFQQDSLFRRNRRLAVFDMDSTLIEAEVIDELAKAAGVGEQVSEITER
AMRGELDFSESFKERLALLKGLDVSVLDEIGASLRLTEGAETLFSELKRLGYKTAILSGGFTYFAKQLQAKLGIDYVFAN
ELEVVDGKVTGVAVEPIVNAQRKADLLRELAHKEGLSLEQTIAVGDGANDLPMLAIAGLGVAFRAKPLVKQSAKQAISTL
GLDGVLYLLGLRDREGKR

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=199, Percent_Identity=34.6733668341709, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1790849, Length=226, Percent_Identity=49.1150442477876, Blast_Score=203, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6321647, Length=229, Percent_Identity=47.5982532751092, Blast_Score=200, Evalue=4e-52,
Organism=Drosophila melanogaster, GI24661601, Length=185, Percent_Identity=30.8108108108108, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 45559; Mature: 45559

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLECVFFPLRGCALREIVLINITGVDRPGLTAAITGVLAQGGVNILDIGQAVIHDTLSF
CCEEEEEEHHCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GILVEIPDTVQGSSVLKDILFTAYELDQQVRFTAVSETDYQHWVEGQGKARHIVTLLTRK
CEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCCHHHHHHHHHHH
VTAEQLQRVSAITARYGLNIDQIDRLSGRMPLDTPADKGKGCIEFTVRGEPADPKAMQAE
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
FLAVAQDLDVDIAFQQDSLFRRNRRLAVFDMDSTLIEAEVIDELAKAAGVGEQVSEITER
HHHHHHCCCEEEEECCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
AMRGELDFSESFKERLALLKGLDVSVLDEIGASLRLTEGAETLFSELKRLGYKTAILSGG
HHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCHHHHHHHHHHCCCHHHHHCCC
FTYFAKQLQAKLGIDYVFANELEVVDGKVTGVAVEPIVNAQRKADLLRELAHKEGLSLEQ
HHHHHHHHHHHHCCEEEEECCEEEECCEEEEEEECHHHCHHHHHHHHHHHHHHCCCCHHH
TIAVGDGANDLPMLAIAGLGVAFRAKPLVKQSAKQAISTLGLDGVLYLLGLRDREGKR
EEEECCCCCCCHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHEECCCCCCCC
>Mature Secondary Structure
MWLECVFFPLRGCALREIVLINITGVDRPGLTAAITGVLAQGGVNILDIGQAVIHDTLSF
CCEEEEEEHHCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GILVEIPDTVQGSSVLKDILFTAYELDQQVRFTAVSETDYQHWVEGQGKARHIVTLLTRK
CEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCCHHHHHHHHHHH
VTAEQLQRVSAITARYGLNIDQIDRLSGRMPLDTPADKGKGCIEFTVRGEPADPKAMQAE
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
FLAVAQDLDVDIAFQQDSLFRRNRRLAVFDMDSTLIEAEVIDELAKAAGVGEQVSEITER
HHHHHHCCCEEEEECCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
AMRGELDFSESFKERLALLKGLDVSVLDEIGASLRLTEGAETLFSELKRLGYKTAILSGG
HHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCHHHHHHHHHHCCCHHHHHCCC
FTYFAKQLQAKLGIDYVFANELEVVDGKVTGVAVEPIVNAQRKADLLRELAHKEGLSLEQ
HHHHHHHHHHHHCCEEEEECCEEEECCEEEEEEECHHHCHHHHHHHHHHHHHHCCCCHHH
TIAVGDGANDLPMLAIAGLGVAFRAKPLVKQSAKQAISTLGLDGVLYLLGLRDREGKR
EEEECCCCCCCHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA